EfficacyNex-z showed positive results in serum TTR reduction, NT-proBNP, troponin, 6MWT, and other cardiac assessments which continues to signal an efficacy profile in-line with competitor treatments.
Long-term EffectivenessNex-z one-time treatment resulted in a significant reduction of serum TTR, which was durable to 24 months, indicating long-term effectiveness.
Patient OutcomeFirst time data on disease biomarkers indicated stabilization and/or improvement in NT-proBNP, Troponin I, and 6MWT, with 83% of NYHA class I/II patients and 47% of NYHA class III patients showing no worsening in any marker at month 12.