Clinical TrialsVERITAC-2 will evaluate vepdegestrant (vepdeg) monotherapy in 2L+ ER+/HER2- breast cancer vs a fulvestrant control arm, with the potential to show activity in ESR1 WT patients who are still endocrine sensitive.
Market PotentialVepdeg palbo combination data sets precedent for the rest of combination studies given the wide compatibility of vepdeg with different inhibitors.
Safety And EfficacyThe 'full dose' of both agents demonstrated a manageable safety profile, suggesting there were no drug-drug interactions observed.