tiprankstipranks
Trending News
More News >
BioInvent International AB (SE:BINV)
:BINV

BioInvent International AB (BINV) AI Stock Analysis

Compare
2 Followers

Top Page

SE:BINV

BioInvent International AB

(BINV)

Select Model
Select Model
Select Model
Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
kr23.00
▼(-24.09% Downside)
Action:ReiteratedDate:03/01/26
The score is weighed down primarily by weak financial performance (large losses and ongoing cash burn) and bearish technicals (price below key moving averages with negative MACD). The main support comes from constructive earnings-call clinical momentum and partnerships with clear upcoming catalysts, partially offset by the near-term funding runway risk.
Positive Factors
Low Financial Leverage
Very low debt-to-equity provides durable financial flexibility for a development-stage biotech, reducing bankruptcy risk and enabling continued R&D spend or opportunistic partnerships without immediate refinancing pressure over the next 2-6 months.
Very High Gross Margin
Extremely high gross margin indicates the company captures strong economics on recognized revenue (collaborations, milestone receipts), supporting scalable profitability if operating leverage improves and clinical programs translate into commercial or recurring partner revenues.
Secured Near-Term Funding Runway
A confirmed cash buffer through Q1 2027 materially reduces near-term dilution risk and supports continued Phase II development and planned readouts, allowing management to advance prioritized assets without immediate capital raises.
Negative Factors
Persistent Operating Losses
Deep, persistent operating losses reflect ongoing heavy investment in clinical programs and limit internal funding ability. If losses persist, the company may need to raise capital, diluting shareholders and shifting focus from long-term value creation to financing.
Negative Free Cash Flow / Cash Burn
Sustained negative operating and free cash flow indicate structural cash burn tied to R&D and trials. Even with runway, continued negative FCF implies dependence on external capital or milestone receipts, creating execution and dilution risk over the medium term.
Quarterly Revenue Instability
Volatile quarter-to-quarter sales driven by fluctuating production revenue and one-off payments undermines predictable cash generation. Reliance on irregular partner payments or milestones complicates planning and increases funding uncertainty beyond the next few quarters.

BioInvent International AB (BINV) vs. iShares MSCI Sweden ETF (EWD)

BioInvent International AB Business Overview & Revenue Model

Company DescriptionBioInvent International AB (publ), a clinical-stage company, discovers, researches, and develops immuno-modulatory antibodies for the treatment of cancer in Sweden, Europe, the United States, Japan, and internationally. Its lead drug candidate is BI-1206 for the treatment of non-Hodgkin lymphoma and solid tumors. The company also develops tumor associated myeloid cells; cancer-associated regulatory T cells, which modulate the immune system; BT-001 in solid tumors; and BI-1808 and BI-1910, which are anti-TNFR2 antibodies for the treatment of solid tumors and cutaneous T-cell lymphoma. It has a strategic collaboration with Pfizer Inc. for the development of antibodies against tumor-associated myeloid cells; partnership and collaboration with Transgene to co-develskylinop multi-functional oncolytic viruses for treatment of solid tumors; and collaboration and supply agreement with Merck for the clinical development of BI-1808. The Company was incorporated in 1996 and is based in Lund, Sweden.
How the Company Makes MoneyBioInvent International AB generates revenue through a combination of product development partnerships, licensing agreements, and potential milestone payments from collaborations with larger pharmaceutical companies. The company often enters into strategic alliances with other biotech and pharmaceutical firms to co-develop its drug candidates, which can provide upfront payments and funding for research and development. Additionally, BioInvent may receive royalties on future sales of products developed from these collaborations. Their revenue model is heavily reliant on the successful advancement of their therapeutic candidates through clinical trials and subsequent commercialization, which can significantly increase earnings based on the success of their research endeavors and market acceptance of their therapies.

BioInvent International AB Earnings Call Summary

Earnings Call Date:Feb 26, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Apr 29, 2026
Earnings Call Sentiment Positive
The call presents multiple strong clinical data points (notably BI-1808 in ovarian cancer and CTCL, and BI-1206 in NHL) with supportive safety and clear near-term catalysts and collaborations with Merck and AstraZeneca. Financially, Q4 sales fell sharply due to lower contract production while full-year sales increased materially driven by one-time items; operating costs and losses rose and the company states it is financed for only the next 12 months, meaning further financing or partnering will be needed to sustain a larger pivotal development plan. Overall, the positive clinical momentum and strategic partnerships outweigh short-term financial and execution risks, but upcoming readouts will be critical for de-risking future funding and pivotal starts.
Q4-2025 Updates
Positive Updates
Strong BI-1808 clinical efficacy in ovarian cancer (combo with pembrolizumab)
Phase IIa combination data in recurrent ovarian cancer: 24% overall response rate (ORR) and 57% disease control rate (DCR) with 21 evaluable ovarian cancer patients; dataset maturing with additional partial response and conversion of stable disease to PR, and a favorable safety profile.
Robust BI-1808 single-agent activity in T‑cell lymphoma (CTCL)
Monotherapy data in CTCL: 46% ORR and 92% DCR in 13 evaluable CTCL patients, with durable responses (including a complete response in Sézary Syndrome lasting >1 year); EMA orphan drug designation granted for BI-1808 in CTCL.
BI-1206 triplet shows high activity in non-Hodgkin lymphoma
Triplet (BI-1206 + rituximab + acalabrutinib) across follicular, marginal zone and mantle cell lymphoma: maintained ~80% ORR and 100% disease control rate; incremental 4 partial responses and 1 additional stable disease vs prior dataset, demonstrating activity across subtypes and encouraging duration.
Promising solid tumor signals for BI-1206 and advancement to first-line studies
Dose-escalation signals in PD-1/PD-L1 refractory solid tumors (complete and partial responses) supported opening a Phase IIa first-line program with pembrolizumab in non‑small cell lung cancer (NSCLC) and uveal melanoma; first readout expected H2 2026.
Strategic collaborations with large pharma
Supply and collaboration agreements in place with Merck (pembrolizumab combinations) and AstraZeneca (acalabrutinib supply for NHL), enabling first-line combination studies and providing strong external validation for programs.
Dense forward-looking clinical milestone timetable
Multiple near-term catalysts: additional BI-1808 combo and monotherapy Phase IIa readouts mid/late 2026; BI-1206 NHL update mid-2026; first-line BI-1206+KEYTRUDA readout H2 2026; potential pivotal starts in 2027 contingent on data.
Board strengthening and scientific depth
Two experienced board nominees (Kate Hermans, Scott Zinober) and publication of mechanistic/preclinical work that deepens scientific credibility and supports partnering discussions.
Improved full-year net sales (driven by one-time items) and short-term liquidity
Net sales for Jan–Dec 2025 were SEK 226 million vs SEK 45 million in 2024 (increase of SEK 181 million, ~+402%), driven mainly by a SEK 20 million payment (XOMA Royalty transaction) and a SEK 1 million milestone; liquid funds and current investments SEK 593 million at 31 Dec 2025 and company assessed as financed for the coming 12 months.
Negative Updates
Sharp Q4 2025 net sales decline
Q4 2025 net sales SEK 3.0 million vs SEK 21.4 million in Q4 2024 — a decrease of SEK 18.4 million (~-86%), primarily due to lower production revenues for antibodies for customers.
Increase in full-year operating costs and personnel expenses
Operating costs for Jan–Dec increased to SEK 578 million from SEK 516 million in 2024 (+SEK 62 million, ~+12% year-over-year), driven by higher costs in BI-1808 and BI-1206 programs and higher personnel costs.
Significant reported losses
Result for Q4 2025: negative SEK 125.8 million; result for Jan–Dec 2025 reported as SEK 332.9 million (presented as the result figure in the call), reflecting continued investment and cash burn.
Revenue mix reliant on one-time items and lower customer production
Full-year net sales uplift largely attributable to a one-time SEK 20 million payment (XOMA Royalty transaction) and a SEK 1 million milestone; production-of-antibodies-for-customers revenue was SEK 19 million lower in 2025, indicating less recurring commercial revenue.
Near-term financing and execution dependency on upcoming data and partnering
Management states the company is financed for 12 months based on ongoing studies but emphasizes partnering and/or financing options for 2027 — implying runway beyond 12 months depends on successful partnering or capital raises tied to clinical readouts.
High efficacy bar and regulatory/workflow uncertainty for pivotal progression
Management targets ~60% ORR as an efficacy threshold in first-line NSCLC for BI-1206 combinations (a demanding benchmark); pivotal starts (especially in 2027) remain contingent on mid‑2026 data and regulatory discussions, introducing execution risk.
Company Guidance
The management outlined a dense near‑term catalyst calendar and clear go/no‑go signals: clinical readouts are expected mid‑2026 (first Phase IIa BI‑1808+pembro in CTCL; additional BI‑1206 triplet NHL data) and in 2H‑2026 (further BI‑1808+pembro solid‑tumor data and first readout from BI‑1206+pembro in first‑line NSCLC and uveal melanoma), with concrete 2027 inflection points including completion of BI‑1808 monotherapy dose optimization in 1H‑2027 and potential pivotal starts (BI‑1808 pivotal in 2H‑2027; BI‑1206 NHL pivotal potentially 1H‑2027; BI‑1206 Phase IIb in NSCLC possibly 2H‑2027). Key clinical metrics already reported: BI‑1808 ovarian combo ORR 24% and disease control rate 57% (21 ovarian patients available), BI‑1808 CTCL monotherapy 46% ORR and 92% disease control in 13 evaluable CTCL patients (including a CR >1 year), BI‑1206 triplet in NHL ~80% ORR and 100% disease control (activity across follicular, marginal zone and mantle cell; current cohort ~30 patients), and a target benchmark of ~60% ORR for BI‑1206 in first‑line NSCLC to consider advancement. Financially, Q4‑2025 net sales were SEK 3m (vs SEK 21.4m a year earlier), full‑year net sales SEK 226m (vs SEK 45m), Q4 operating costs SEK 132m (Q4‑2024 SEK 147m), full‑year operating costs SEK 578m (2024 SEK 516m), Q4 result −SEK 125.8m and full‑year result −SEK 332.9m, with liquid funds/current investments of SEK 593m and the company assessed as financed for the coming 12 months.

BioInvent International AB Financial Statement Overview

Summary
Operating fundamentals are weak with volatile revenue, deeply negative profitability, and persistent negative operating/free cash flow. The main offset is a low-leverage balance sheet, but equity erosion and large losses keep financial strength constrained.
Income Statement
24
Negative
Revenue has been volatile and recently weaker (2025 revenue down ~7.5% vs. 2024), and profitability remains deeply negative. 2025 shows a very large net loss (net margin roughly -147%) and negative operating results, after an already weak 2023–2024 period. While 2022 was comparatively better (smaller loss on much higher revenue), the overall trajectory points to inconsistent top-line performance and sustained losses.
Balance Sheet
66
Positive
The balance sheet is a relative strength: leverage is very low (debt-to-equity ~1.7% in 2025), providing financial flexibility. However, equity has declined materially from 2022–2023 levels, and returns on equity are sharply negative (about -60% in 2025), reflecting ongoing value erosion from losses despite modest debt.
Cash Flow
30
Negative
Cash generation is weak with persistent cash burn: operating cash flow and free cash flow are negative across all years shown, including 2025 (operating cash flow about -248M; free cash flow about -255M). Cash burn improved versus 2024, but free cash flow still deteriorated slightly year over year (2025 free cash flow growth ~-2.8%). Free cash flow roughly tracks the net loss (free cash flow to net income ~1.03 in 2025), indicating losses are translating into real cash outflows rather than being primarily non-cash.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue226.50M44.69M71.46M326.13M19.38M
Gross Profit0.0044.69M71.46M326.13M19.38M
EBITDA-331.52M-409.38M-312.71M-27.13M-263.32M
Net Income-332.86M-429.38M-330.30M-34.09M-278.96M
Balance Sheet
Total Assets671.20M989.24M1.40B1.71B1.45B
Cash, Cash Equivalents and Short-Term Investments592.75M867.16M1.07B1.02B1.08B
Total Debt9.68M17.41M23.24M26.96M28.37M
Total Liabilities113.59M103.42M90.45M106.09M80.32M
Stockholders Equity557.62M885.82M1.31B1.61B1.37B
Cash Flow
Free Cash Flow-255.01M-390.50M-355.00M-53.60M-259.10M
Operating Cash Flow-247.75M-380.47M-341.69M-41.23M-245.84M
Investing Cash Flow180.13M564.35M59.68M-628.85M-467.54M
Financing Cash Flow-8.98M-8.46M23.14M273.49M894.87M

BioInvent International AB Technical Analysis

Technical Analysis Sentiment
Negative
Last Price30.30
Price Trends
50DMA
28.40
Negative
100DMA
28.82
Negative
200DMA
31.72
Negative
Market Momentum
MACD
-1.16
Positive
RSI
29.41
Positive
STOCH
26.94
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SE:BINV, the sentiment is Negative. The current price of 30.3 is above the 20-day moving average (MA) of 26.57, above the 50-day MA of 28.40, and below the 200-day MA of 31.72, indicating a bearish trend. The MACD of -1.16 indicates Positive momentum. The RSI at 29.41 is Positive, neither overbought nor oversold. The STOCH value of 26.94 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SE:BINV.

BioInvent International AB Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
kr2.57B8.92167.77%2687.51%
58
Neutral
kr2.83B-5.06-71.87%-91.85%-6.65%
56
Neutral
kr3.44B-5.25-5.69%21.58%
55
Neutral
kr1.18B8.0181.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
kr1.53B-4.60-36.52%533.73%20.92%
44
Neutral
kr1.09B-5.90-35.03%25.14%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SE:BINV
BioInvent International AB
23.25
-3.55
-13.25%
SE:HNSA
Hansa Biopharma AB
33.80
9.44
38.75%
SE:SANION
Saniona AB
18.62
11.87
175.85%
SE:VICO
Vicore Pharma Holding AB
10.06
2.17
27.50%
SE:XSPRAY
Xspray Pharma AB
26.20
-4.94
-15.85%
SE:CANTA
Cantargia AB
4.74
3.15
198.93%

BioInvent International AB Corporate Events

BioInvent doubles down on lead cancer antibodies as 2026 data catalysts loom
Feb 26, 2026

BioInvent has sharpened its clinical focus and resource allocation in 2025 to advance its lead oncology assets BI-1808 and BI-1206, pausing earlier-stage programs to maximize the probability of success and near-term value. The company reported improved full-year net sales, reduced losses versus 2024 and a solid cash position, while securing key regulatory designations, new patents and ESG verification, which collectively strengthen its competitive and financial footing.

The year saw promising Phase 2a data for BI-1808 in T-cell lymphoma and in combination with pembrolizumab in ovarian cancer, as well as impressive results for a BI-1206 triplet regimen in relapsed or refractory non-Hodgkin’s lymphoma presented at major medical meetings. Looking ahead, BioInvent is guiding to a series of 2026 data catalysts across CTCL, NHL, solid tumors, NSCLC and uveal melanoma, milestones that could significantly influence its clinical trajectory, partnership potential and value perception among investors and other stakeholders.

Additional developments included orphan drug and fast track designations for BI-1808 in T-cell lymphomas from U.S. and European regulators, validation of the TNFR2 target via Phase 1 data on the paused antibody BI-1910, and updated data on other pipeline assets such as BT-001 and BI-1607. The company also realized non-dilutive value through a royalty sale to XOMA, and proposed two new board members to support its next stage of growth.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK31.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

BioInvent to Present 2025 Year-End Results in Investor Webcast
Feb 26, 2026

BioInvent International AB is a clinical-stage biotechnology company specializing in immuno-oncology, developing novel immuno-modulatory antibody therapies for hematological cancers and solid tumors. Leveraging its proprietary F.I.R.S.T. discovery platform, the company advances its own clinical pipeline while securing revenues from research collaborations, licensing deals, and third-party antibody manufacturing.

The company has invited investors, analysts, and media to a webcast and conference call on 26 February 2026 for the presentation of its 2025 year-end report, to be held in English by CEO Martin Welschof and CFO Stefan Ericsson. The event is designed to provide detailed financial and operational updates and will later be accessible via the company’s website, underscoring ongoing engagement with the capital markets and other stakeholders ahead of a potentially pivotal phase in its clinical and partnering activities.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK31.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

BioInvent Taps Industry Heavyweights for Board as Cancer Pipeline Advances
Feb 23, 2026

BioInvent has nominated global life sciences executive Kate Hermans and veteran healthcare investor Scott Zinober to join its Board of Directors, with their elections to be put to shareholders at the April 29, 2026 AGM. The move comes as the company advances key clinical candidates BI-1808 and BI-1206 and prepares for the transition toward late-stage development and potential commercialization.

Hermans brings more than 25 years of leadership in biopharma and high-tech, including steering Ambrx Biopharma through a transformation that led to its $2 billion sale to Johnson & Johnson, along with senior roles at major pharma and biotech firms. Zinober adds deep capital markets and healthcare investment expertise from over two decades at Viking Global Investors, positioning BioInvent to strengthen its financing strategies and global immuno-oncology profile as several existing board members step down.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK31.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

BioInvent Posts Strong Interim Data for BI‑1808 and KEYTRUDA Combo in Recurrent Ovarian Cancer
Jan 5, 2026

BioInvent International has reported encouraging interim Phase 2a data for its first‑in‑class anti‑TNFR2 antibody BI‑1808 in combination with Merck’s anti‑PD‑1 therapy KEYTRUDA (pembrolizumab) in patients with recurrent ovarian cancer who have progressed after platinum‑based treatment. Among 17 evaluable patients, the combination achieved a 24% overall response rate and 65% disease control rate, a marked improvement over the 8% response rate previously seen with pembrolizumab monotherapy in this setting, with responses including durable stable disease beyond eight months and a generally favorable safety and tolerability profile. Exploratory analyses suggest strong activity in high‑grade serous and clear cell ovarian cancer subtypes, prompting BioInvent to expand the ovarian cancer cohort by enrolling an additional 20 patients, with results expected in the second half of 2026, potentially strengthening the company’s position in immuno‑oncology and offering a new treatment avenue for a patient population with few effective options.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK28.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

BioInvent Steps Up Investor Outreach with Series of 2026 Healthcare Conferences
Dec 18, 2025

BioInvent International AB will seek to deepen engagement with global investors and industry partners in January 2026 through participation in several high-profile investor and healthcare conferences in San Francisco and Stockholm. The company’s management will hold one-on-one meetings at the J.P. Morgan 2026 Healthcare Conference and the LifeSci Partners Corporate Access Event, join a Swedish-focused panel at the J.P. Morgan networking breakfast, and present with a Q&A session at the Redeye Fight Cancer event, moves that underscore its efforts to raise visibility around its cancer immunotherapy pipeline and to support potential partnering and financing opportunities.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK28.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

BioInvent Reports Promising Phase 2a Trial Results for NHL Treatment
Dec 8, 2025

BioInvent International AB announced promising early data from its Phase 2a trial of BI-1206 in combination with rituximab and Calquence for the treatment of relapsed/refractory non-Hodgkin’s lymphoma (NHL). The trial showed an 80% overall response rate, with 47% of patients achieving complete responses and a favorable safety profile, suggesting the potential of this combination to overcome resistance to rituximab and provide a new therapeutic option for patients with limited alternatives.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK28.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

BioInvent’s BI-1808 Shows Promise in Early Phase 2a CTCL Trial
Dec 7, 2025

BioInvent International AB has presented promising early Phase 2a data for its BI-1808 monotherapy in treating cutaneous T-cell lymphoma (CTCL) at the ASH 2025 meeting. The trial showed a 46% objective response rate and a 92% disease control rate among evaluable patients, with evidence of immune activation. The company is also exploring BI-1808 in combination with pembrolizumab for solid tumors, positioning itself for significant market opportunities with Fast Track and Orphan Drug designations.

The most recent analyst rating on (SE:BINV) stock is a Hold with a SEK28.00 price target. To see the full list of analyst forecasts on BioInvent International AB stock, see the SE:BINV Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 01, 2026