Positive Data for Lead Compound BI-1206
The company reported additional positive data for their lead compound BI-1206, targeting FcgammaRIIB, especially for the subcutaneous formulation, with 2 complete responses, 3 partial responses, and 3 stable diseases out of 9 evaluable patients.
Progress in BI-1808 and BI-1910 Programs
BI-1808 showed 3 partial responses and 1 stable disease out of 4 evaluable patients in the CTCL cohort. BI-1910 received a Notice of Allowance and showed robust target occupancy in trials.
Successful Subcutaneous Formulation
The subcutaneous (subcu) formulation of BI-1206 showed improved activity and safety profile compared to the intravenous version, eliminating infusion-related reactions.
Strategic Collaborations
New clinical trial collaboration and supply agreements were established with Merck for BI-1607, and with AstraZeneca for BI-1206 in a triplet combination with rituximab and acalabrutinib.
Promising Anti-CTLA-4 Antibody Data
The anti-CTLA-4 antibody in combination with pembrolizumab showed tumor regression in patients who failed previous anti-PD-L1 treatment.
Strong Financial Position
The company has liquid funds of SEK 979 million, providing a financial runway until the end of Q1 2026.