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Relay Therapeutics Inc (RLAY)
:RLAY
US Market
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Relay Therapeutics (RLAY) AI Stock Analysis

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RLAY

Relay Therapeutics

(NASDAQ:RLAY)

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Neutral 55 (OpenAI - 4o)
Rating:55Neutral
Price Target:
$4.00
▼(-8.68% Downside)
Relay Therapeutics' overall stock score is primarily influenced by its financial performance challenges, including ongoing losses and cash flow difficulties. Technical analysis provides a neutral outlook, while valuation remains a concern due to a negative P/E ratio. However, the recent corporate event of lease termination positively impacts the score by demonstrating cost-saving measures.
Positive Factors
Strategic Leadership Change
The appointment of Claire Mazumdar brings strategic guidance as Relay prepares for its Phase 3 trial, potentially enhancing operations and market positioning.
Cost Management
The lease termination agreement reflects effective cost management, improving operational efficiency and freeing up resources for strategic initiatives.
Governance Stability
The election of directors and approval of executive compensation indicate governance stability, supporting long-term strategic goals and stakeholder confidence.
Negative Factors
Revenue Volatility
Revenue volatility poses challenges for predictable cash flow and strategic planning, impacting the company's ability to sustain growth and investment.
Cash Flow Challenges
Persistent negative cash flows highlight inefficiencies in operations, limiting the company's ability to reinvest in growth and manage financial obligations.
Profitability Issues
Ongoing profitability issues hinder Relay's capacity to generate returns, affecting its financial health and ability to sustain long-term operations.

Relay Therapeutics (RLAY) vs. SPDR S&P 500 ETF (SPY)

Relay Therapeutics Business Overview & Revenue Model

Company DescriptionRelay Therapeutics, Inc. operates as a clinical-stage precision medicines company. It engages in transforming the drug discovery process with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology and genetic disease indications. The company's lead product candidates include RLY-4008, an oral small molecule inhibitor of fibroblast growth factor receptor 2 (FGFR2), which is in a first-in-human clinical trial for patients with advanced or metastatic FGFR2-altered solid tumors; RLY-2608, a lead mutant-PI3Ka inhibitor program that targets phosphoinostide 3 kinase alpha; and RLY-1971, an oral small molecule inhibitor of protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-2 that is in Phase 1 trial in patients with advanced solid tumors. It has collaboration and license agreements with D. E. Shaw Research, LLC to research certain biological targets through the use of D. E. Shaw Research computational modeling capabilities focused on analysis of protein motion to develop and commercialize compounds and products directed to such targets; and Genentech, Inc. for the development and commercialization of RLY-1971. The company was formerly known as Allostery, Inc. and changed its name to Relay Therapeutics, Inc. in December 2015. Relay Therapeutics, Inc. was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyRelay Therapeutics generates revenue through a combination of research collaborations, licensing agreements, and potential milestone payments associated with its drug development programs. The company partners with larger pharmaceutical companies to co-develop drug candidates, which can lead to upfront payments, research funding, and royalties on future sales. Additionally, as Relay Therapeutics advances its candidates into clinical trials and achieves specific developmental milestones, it may receive milestone payments from its partners. The success of its drug candidates in clinical trials can also lead to lucrative licensing deals, further enhancing its revenue streams.

Relay Therapeutics Financial Statement Overview

Summary
Relay Therapeutics faces ongoing challenges in achieving profitability and positive cash flow. While the balance sheet remains stable with low leverage, the income statement reveals significant losses and operational challenges. The cash flow statement highlights the difficulty in generating sustainable cash flows. Overall, while there are strengths in equity financing and asset management, profitability and cash generation remain critical concerns.
Income Statement
45
Neutral
Relay Therapeutics has experienced volatility in revenue, with significant fluctuations over the years. The gross profit margin is positive in recent years, but the company consistently reports negative net income, resulting in a negative net profit margin. EBIT and EBITDA margins are also negative, indicating operational challenges. The revenue has shown growth over the past year, but the overall trajectory remains uncertain.
Balance Sheet
55
Neutral
The balance sheet of Relay Therapeutics is relatively strong with a high equity ratio, indicating a larger proportion of assets financed by equity. The company has a low debt-to-equity ratio, suggesting manageable leverage. However, the consistent net losses impact the return on equity negatively. Overall, the company maintains a stable financial position despite ongoing losses.
Cash Flow
50
Neutral
Relay Therapeutics has faced challenges generating positive cash flow, with negative free and operating cash flows. The free cash flow has been declining, indicating cash constraints. The operating cash flow to net income ratio is negative, reflecting inefficiencies in converting profits to cash. While the company has been able to access financing, it remains cash flow negative.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue8.36M10.01M25.55M1.38M3.03M82.65M
Gross Profit-1.26M-305.43M25.55M-241.62M-166.36M79.11M
EBITDA-340.36M-380.21M-374.15M-306.82M-222.18M-52.25M
Net Income-311.55M-337.71M-341.97M-290.51M-363.87M-52.41M
Balance Sheet
Total Assets728.84M871.30M843.98M1.10B1.01B799.83M
Cash, Cash Equivalents and Short-Term Investments113.94M781.32M750.09M998.92M958.07M678.06M
Total Debt34.18M48.50M53.47M57.74M22.90M24.42M
Total Liabilities63.18M93.50M91.98M149.55M110.64M36.54M
Stockholders Equity665.66M777.79M752.00M950.22M897.81M763.29M
Cash Flow
Free Cash Flow-262.06M-251.13M-304.44M-238.55M-77.88M-104.42M
Operating Cash Flow-261.42M-249.11M-300.32M-229.49M-74.41M-102.49M
Investing Cash Flow20.45M-41.08M257.63M-188.75M-479.51M81.67M
Financing Cash Flow220.34M270.15M34.75M289.91M388.09M426.51M

Relay Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.38
Price Trends
50DMA
3.77
Positive
100DMA
3.51
Positive
200DMA
3.62
Positive
Market Momentum
MACD
0.23
Negative
RSI
60.32
Neutral
STOCH
66.08
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RLAY, the sentiment is Positive. The current price of 4.38 is above the 20-day moving average (MA) of 4.14, above the 50-day MA of 3.77, and above the 200-day MA of 3.62, indicating a bullish trend. The MACD of 0.23 indicates Negative momentum. The RSI at 60.32 is Neutral, neither overbought nor oversold. The STOCH value of 66.08 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RLAY.

Relay Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
854.00M-4.40-50.24%
55
Neutral
$779.30M-46.24%-76.27%22.77%
49
Neutral
848.56M-9.58-33.91%11877.28%63.14%
48
Neutral
890.96M-10.08-15.91%83.36%22.27%
47
Neutral
867.83M-6.00-107.86%-42.84%-17.32%
29
Underperform
800.45M-4.644.97%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RLAY
Relay Therapeutics
4.38
-3.02
-40.81%
GERN
Geron
1.27
-3.16
-71.33%
IMTX
Immatics
7.05
-4.68
-39.90%
TNGX
Tango Therapeutics
7.97
0.61
8.29%
PROK
ProKidney
2.62
0.58
28.43%
ZBIO
Zenas BioPharma, Inc.
18.62
1.33
7.69%

Relay Therapeutics Corporate Events

Executive/Board ChangesBusiness Operations and Strategy
Claire Mazumdar Joins Relay Therapeutics as Director
Neutral
Jun 11, 2025

On June 8, 2025, Jami Ruben resigned from the Board of Directors and Audit Committee of Relay Therapeutics, with no disputes involved. Subsequently, on June 9, 2025, Claire Mazumdar was appointed as a Class III Director and chair of the Audit Committee. Her appointment is expected to bring strategic guidance as Relay Therapeutics prepares for its Phase 3 ReDiscover-2 trial in breast cancer, potentially impacting the company’s operations and market positioning.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 23, 2025