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Relay Therapeutics Inc (RLAY)
NASDAQ:RLAY
US Market
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Relay Therapeutics (RLAY) AI Stock Analysis

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RLAY

Relay Therapeutics

(NASDAQ:RLAY)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$13.00
▼(-22.43% Downside)
Action:Reiterated
Date:05/22/26
The score is held down primarily by persistent large losses and substantial ongoing cash burn, despite a low-debt balance sheet. Technicals are moderately supportive with price above longer-term moving averages, while valuation remains challenged by unprofitability and no dividend. Positive pipeline-related corporate updates and added funding runway help offset, but dilution risk remains.
Positive Factors
Computational-experimental drug discovery platform
Relay’s integrated computational and experimental platform is a durable competitive asset: it improves understanding of protein motion, can raise hit-to-lead efficiency and de-risk candidate selection, and supports repeatable discovery across oncology and genetic-disease programs over multi-quarter timelines.
Negative Factors
High and persistent cash burn
Sustained negative operating and free cash flow (~-$213M TTM) means the business relies on external capital to fund R&D. If clinical timelines slip or milestones are delayed, recurring cash burn will force additional financing, raising execution risk and potential for further dilution over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Computational-experimental drug discovery platform
Relay’s integrated computational and experimental platform is a durable competitive asset: it improves understanding of protein motion, can raise hit-to-lead efficiency and de-risk candidate selection, and supports repeatable discovery across oncology and genetic-disease programs over multi-quarter timelines.
Read all positive factors

Relay Therapeutics (RLAY) vs. SPDR S&P 500 ETF (SPY)

Relay Therapeutics Business Overview & Revenue Model

Company Description
Relay Therapeutics, Inc. operates as a clinical-stage precision medicines company. It engages in transforming the drug discovery process with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology and genetic disea...
How the Company Makes Money
Relay Therapeutics has historically generated revenue primarily from collaboration and licensing arrangements (rather than product sales), because it is a clinical-stage company without widely commercialized, approved therapeutics. Under these typ...

Relay Therapeutics Financial Statement Overview

Summary
Financial quality is constrained by deep losses and heavy cash burn (TTM net income about -$273M; operating/free cash flow about -$213M), despite strong gross margin (~90%). The balance sheet is a relative support with low leverage (debt-to-equity ~0.05), but declining equity/assets and highly negative ROE (~-44%) highlight ongoing funding/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue10.68M15.36M10.01M25.55M1.38M3.03M
Gross Profit9.57M11.80M10.01M25.55M1.38M3.03M
EBITDA-291.42M-272.92M-380.21M-374.15M-306.82M-223.08M
Net Income-272.70M-276.48M-337.71M-341.97M-290.51M-363.87M
Balance Sheet
Total Assets699.61M621.33M871.30M843.98M1.10B1.01B
Cash, Cash Equivalents and Short-Term Investments642.07M554.52M781.32M750.09M998.92M958.07M
Total Debt31.57M32.46M48.50M53.47M57.74M22.90M
Total Liabilities57.43M54.27M93.50M91.98M149.55M110.64M
Stockholders Equity642.18M567.06M777.79M752.00M950.22M897.81M
Cash Flow
Free Cash Flow-213.38M-235.87M-251.13M-304.44M-238.55M-77.88M
Operating Cash Flow-213.36M-235.46M-249.11M-300.32M-229.49M-74.41M
Investing Cash Flow183.24M192.80M-41.08M257.63M-188.75M-479.51M
Financing Cash Flow140.39M1.60M270.15M34.75M289.91M388.09M

Relay Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price16.76
Price Trends
50DMA
12.79
Positive
100DMA
10.73
Positive
200DMA
8.32
Positive
Market Momentum
MACD
-0.08
Negative
RSI
54.36
Neutral
STOCH
56.71
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RLAY, the sentiment is Positive. The current price of 16.76 is above the 20-day moving average (MA) of 12.94, above the 50-day MA of 12.79, and above the 200-day MA of 8.32, indicating a bullish trend. The MACD of -0.08 indicates Negative momentum. The RSI at 54.36 is Neutral, neither overbought nor oversold. The STOCH value of 56.71 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RLAY.

Relay Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$2.59B-6.10-43.94%39.04%29.88%
52
Neutral
$2.93B-16.50-41.54%39.04%32.40%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.20B-3.36-167.71%-100.00%-128.73%
47
Neutral
$1.56B-4.88-45.47%-72.09%-754.83%
47
Neutral
$821.15M-68.46-28.90%68.64%50.57%
44
Neutral
$528.43M-2.817.40%190.52%12.60%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RLAY
Relay Therapeutics
13.53
10.68
374.74%
GERN
Geron
1.28
-0.17
-11.72%
IMTX
Immatics
11.62
6.51
127.40%
TNGX
Tango Therapeutics
20.24
18.19
887.32%
PROK
ProKidney
1.75
1.02
139.73%
ZBIO
Zenas BioPharma, Inc.
18.97
8.41
79.64%

Relay Therapeutics Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Relay Therapeutics Announces Major Underwritten Equity Offering
Positive
May 22, 2026
On May 20, 2026, Relay Therapeutics entered into an underwriting agreement with Jefferies and TD Securities for an underwritten public offering of 22,916,667 shares of common stock at $12.00 per share, with underwriters granted a 30‑day opti...
Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics reports promising Phase 2 zovegalisib data
Positive
May 19, 2026
Relay Therapeutics on May 19, 2026 reported initial Phase 2 ReInspire data for its PI3Kα mutant-selective inhibitor zovegalisib in PIK3CA-driven vascular anomalies, showing a 60% volumetric response rate at 12 weeks among 20 evaluable adults ...
Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics advances zovegalisib combo in breast cancer
Positive
Apr 27, 2026
On April 27, 2026, Relay Therapeutics reported Phase 1/2 ReDiscover data for its triplet regimen of zovegalisib, atirmociclib and fulvestrant in heavily pre-treated, CDK4/6-experienced patients with PI3Kα-mutated, HR+/HER2- metastatic breast ...
Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics Highlights Positive Zovegalisib ReDiscover Trial Data
Positive
Mar 16, 2026
On March 16, 2026, Relay Therapeutics reported Phase 1/2 ReDiscover data for its PI3Kα inhibitor zovegalisib combined with fulvestrant at the recommended Phase 3 dose of 400mg twice daily taken with food in patients with PI3Kα‑muta...
Business Operations and StrategyRegulatory Filings and Compliance
Relay Therapeutics Updates Bylaws on Federal Securities Litigation
Positive
Mar 12, 2026
On March 6, 2026, Relay Therapeutics, Inc. amended and restated its bylaws to specify that federal district courts in the United States will serve as the exclusive forum for complaints arising under the Securities Act of 1933 and the Securities Ex...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 22, 2026