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Relay Therapeutics Inc (RLAY)
NASDAQ:RLAY
US Market
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Relay Therapeutics (RLAY) AI Stock Analysis

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RLAY

Relay Therapeutics

(NASDAQ:RLAY)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$13.00
▼(-22.43% Downside)
Action:ReiteratedDate:04/29/26
Score is held back primarily by weak financial performance (large ongoing losses and cash burn, despite low leverage). Offsetting factors include improving technical trend/momentum and a string of positive clinical/regulatory corporate events; valuation remains constrained by negative earnings and no dividend yield support.
Positive Factors
Regulatory validation (Breakthrough Therapy)
Breakthrough Therapy designation is a durable structural plus: it signals strong clinical differentiation, can speed development and regulatory review, and raises the probability of approval. This sustained regulatory validation improves strategic partnerships and long-term commercialization prospects.
Negative Factors
Sustained cash burn
Persistent negative operating and free cash flow is a structural weakness: ongoing cash burn forces reliance on external financing or milestone receipts, increasing dilution risk, potentially delaying programs or forcing prioritization of assets, and constraining long-term strategic flexibility.
Read all positive and negative factors
Positive Factors
Negative Factors
Regulatory validation (Breakthrough Therapy)
Breakthrough Therapy designation is a durable structural plus: it signals strong clinical differentiation, can speed development and regulatory review, and raises the probability of approval. This sustained regulatory validation improves strategic partnerships and long-term commercialization prospects.
Read all positive factors

Relay Therapeutics (RLAY) vs. SPDR S&P 500 ETF (SPY)

Relay Therapeutics Business Overview & Revenue Model

Company Description
Relay Therapeutics, Inc. operates as a clinical-stage precision medicines company. It engages in transforming the drug discovery process with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology and genetic disea...
How the Company Makes Money
Relay Therapeutics has historically generated revenue primarily from collaboration and licensing arrangements (rather than product sales), because it is a clinical-stage company without widely commercialized, approved therapeutics. Under these typ...

Relay Therapeutics Financial Statement Overview

Summary
Overall financial profile is weak due to persistent large operating/net losses and sustained negative operating and free cash flow (ongoing cash burn). The balance sheet is a relative positive with low leverage, but equity has declined meaningfully, and the 2025 revenue rebound does not yet offset profitability and cash-flow weakness.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue15.36M10.01M25.55M1.38M3.03M
Gross Profit11.80M10.01M25.55M1.38M3.03M
EBITDA-272.92M-380.21M-374.15M-306.82M-223.08M
Net Income-276.48M-337.71M-341.97M-290.51M-363.87M
Balance Sheet
Total Assets621.33M871.30M843.98M1.10B1.01B
Cash, Cash Equivalents and Short-Term Investments554.52M781.32M750.09M998.92M958.07M
Total Debt32.46M48.50M53.47M57.74M22.90M
Total Liabilities54.27M93.50M91.98M149.55M110.64M
Stockholders Equity567.06M777.79M752.00M950.22M897.81M
Cash Flow
Free Cash Flow-235.87M-251.13M-304.44M-238.55M-77.88M
Operating Cash Flow-235.46M-249.11M-300.32M-229.49M-74.41M
Investing Cash Flow192.80M-41.08M257.63M-188.75M-479.51M
Financing Cash Flow1.60M270.15M34.75M289.91M388.09M

Relay Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price16.76
Price Trends
50DMA
10.72
Positive
100DMA
9.35
Positive
200DMA
7.08
Positive
Market Momentum
MACD
1.68
Negative
RSI
81.43
Negative
STOCH
90.86
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RLAY, the sentiment is Positive. The current price of 16.76 is above the 20-day moving average (MA) of 12.49, above the 50-day MA of 10.72, and above the 200-day MA of 7.08, indicating a bullish trend. The MACD of 1.68 indicates Negative momentum. The RSI at 81.43 is Negative, neither overbought nor oversold. The STOCH value of 90.86 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RLAY.

Relay Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$3.03B-10.13-50.30%48.29%28.08%
54
Neutral
$1.01B-10.26-34.23%138.82%52.84%
52
Neutral
$2.41B-5.25-43.17%53.45%32.76%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$1.45B-5.79-39.69%-67.98%-2353.85%
50
Neutral
$1.11B-1.76-156.98%100.00%-116.54%
45
Neutral
$582.70M-3.936.86%1075.00%18.02%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RLAY
Relay Therapeutics
13.09
9.77
294.28%
GERN
Geron
1.57
0.15
10.56%
IMTX
Immatics
11.14
6.04
118.43%
TNGX
Tango Therapeutics
22.71
21.29
1499.30%
PROK
ProKidney
1.88
1.13
150.67%
ZBIO
Zenas BioPharma, Inc.
21.56
10.32
91.81%

Relay Therapeutics Corporate Events

Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics advances zovegalisib combo in breast cancer
Positive
Apr 27, 2026
On April 27, 2026, Relay Therapeutics reported Phase 1/2 ReDiscover data for its triplet regimen of zovegalisib, atirmociclib and fulvestrant in heavily pre-treated, CDK4/6-experienced patients with PI3Kα-mutated, HR+/HER2- metastatic breast ...
Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics Highlights Positive Zovegalisib ReDiscover Trial Data
Positive
Mar 16, 2026
On March 16, 2026, Relay Therapeutics reported Phase 1/2 ReDiscover data for its PI3Kα inhibitor zovegalisib combined with fulvestrant at the recommended Phase 3 dose of 400mg twice daily taken with food in patients with PI3Kα‑muta...
Business Operations and StrategyRegulatory Filings and Compliance
Relay Therapeutics Updates Bylaws on Federal Securities Litigation
Positive
Mar 12, 2026
On March 6, 2026, Relay Therapeutics, Inc. amended and restated its bylaws to specify that federal district courts in the United States will serve as the exclusive forum for complaints arising under the Securities Act of 1933 and the Securities Ex...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Relay Therapeutics Wins FDA Breakthrough Therapy Designation
Positive
Feb 3, 2026
On February 3, 2026, Relay Therapeutics announced that the U.S. Food and Drug Administration granted Breakthrough Therapy designation to its lead drug candidate zovegalisib (RLY-2608), in combination with fulvestrant, for adults with PIK3CA-mutant...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 29, 2026