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Relay Therapeutics Inc (RLAY)
NASDAQ:RLAY
US Market
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Relay Therapeutics (RLAY) AI Stock Analysis

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RLAY

Relay Therapeutics

(NASDAQ:RLAY)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$20.00
▲(19.33% Upside)
Action:Reiterated
Date:06/23/26
The score is held down primarily by weak financial performance (large ongoing losses and substantial negative free cash flow). Technicals provide a meaningful offset via strong trend and positive momentum, while valuation remains pressured due to unprofitable earnings. Corporate events are moderately supportive on pipeline progress but tempered by dilution-related financing actions.
Positive Factors
Proprietary discovery platform
Relay's computational, structure-based platform that emphasizes protein motion is a durable competitive advantage. It can shorten discovery cycles, create differentiated molecules for genetically defined cancers, and make the company an attractive partner across programs, supporting long‑term pipeline productivity and licensing opportunities.
Negative Factors
High cash burn
Sustained negative operating and free cash flow (~-$213M TTM) creates ongoing funding needs. Over the medium term this increases dependency on external financing and can constrain strategic optionality, making long‑term program execution contingent on continued capital access and partnerships.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary discovery platform
Relay's computational, structure-based platform that emphasizes protein motion is a durable competitive advantage. It can shorten discovery cycles, create differentiated molecules for genetically defined cancers, and make the company an attractive partner across programs, supporting long‑term pipeline productivity and licensing opportunities.
Read all positive factors

Relay Therapeutics (RLAY) vs. SPDR S&P 500 ETF (SPY)

Relay Therapeutics Business Overview & Revenue Model

Company Description
Relay Therapeutics, Inc. is a precision medicine company currently engaged in clinical trials. Its central mission involves revolutionizing the drug discovery process, with a particular focus on enhancing the creation of small molecule therapies f...
How the Company Makes Money
Relay Therapeutics primarily generates revenue through collaboration and licensing arrangements rather than product sales, as it is a clinical-stage company without null commercialized products. Key revenue streams include (1) upfront payments and...

Relay Therapeutics Financial Statement Overview

Summary
Overall financial quality is constrained by heavy losses and cash burn (TTM net income about -$273M; operating and free cash flow about -$213M), despite strong gross margin (~90%). The balance sheet is a relative positive with low leverage (debt-to-equity ~0.05), but declining equity/assets and very negative ROE (~-44%) highlight ongoing funding/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue10.68M15.36M10.01M25.55M1.38M3.03M
Gross Profit-119.79M11.80M-305.43M-300.84M-241.62M-166.36M
EBITDA-273.41M-272.92M-380.21M-374.15M-306.82M-223.08M
Net Income-272.70M-276.48M-337.71M-341.97M-290.51M-363.87M
Balance Sheet
Total Assets699.61M621.33M871.30M843.98M1.10B1.01B
Cash, Cash Equivalents and Short-Term Investments642.07M554.52M781.32M750.09M998.92M958.07M
Total Debt31.57M32.46M48.50M53.47M57.74M22.90M
Total Liabilities57.43M54.27M93.50M91.98M149.55M110.64M
Stockholders Equity642.18M567.06M777.79M752.00M950.22M897.81M
Cash Flow
Free Cash Flow-213.38M-235.87M-251.13M-304.44M-238.55M-77.88M
Operating Cash Flow-213.36M-235.46M-249.11M-300.32M-229.49M-74.41M
Investing Cash Flow183.24M192.80M-41.08M257.63M-188.75M-479.51M
Financing Cash Flow140.39M1.60M270.15M34.75M289.91M388.09M

Relay Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price16.76
Price Trends
50DMA
14.97
Positive
100DMA
13.27
Positive
200DMA
10.26
Positive
Market Momentum
MACD
1.47
Negative
RSI
72.43
Negative
STOCH
86.45
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RLAY, the sentiment is Positive. The current price of 16.76 is below the 20-day moving average (MA) of 17.35, above the 50-day MA of 14.97, and above the 200-day MA of 10.26, indicating a bullish trend. The MACD of 1.47 indicates Negative momentum. The RSI at 72.43 is Negative, neither overbought nor oversold. The STOCH value of 86.45 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RLAY.

Relay Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$4.99B-36.77-41.54%39.04%32.40%
58
Neutral
$1.82B-3.23-167.71%-100.00%-128.73%
52
Neutral
$4.28B-13.22-43.94%39.04%29.88%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.00B-14.96-28.90%68.64%50.57%
46
Neutral
$555.79M-3.277.40%190.52%12.60%
44
Neutral
$1.34B-5.09-45.27%-72.09%-754.83%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RLAY
Relay Therapeutics
20.75
17.02
456.30%
GERN
Geron
1.56
0.18
13.04%
IMTX
Immatics
9.96
3.96
66.00%
TNGX
Tango Therapeutics
30.52
24.41
399.51%
PROK
ProKidney
1.80
-3.38
-65.25%
ZBIO
Zenas BioPharma, Inc.
29.43
17.36
143.83%

Relay Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and ComplianceShareholder Meetings
Relay Therapeutics Expands Authorized Shares at 2026 Meeting
Positive
Jun 9, 2026
On June 9, 2026, Relay Therapeutics, Inc. held its 2026 Annual Meeting of Stockholders, where shareholders elected Douglas S. Ingram and Claire Mazumdar, Ph.D., as class III directors to serve three-year terms ending at the 2029 annual meeting. In...
Business Operations and StrategyPrivate Placements and Financing
Relay Therapeutics Announces Major Underwritten Equity Offering
Positive
May 22, 2026
On May 20, 2026, Relay Therapeutics entered into an underwriting agreement with Jefferies and TD Securities for an underwritten public offering of 22,916,667 shares of common stock at $12.00 per share, with underwriters granted a 30‑day opti...
Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics reports promising Phase 2 zovegalisib data
Positive
May 19, 2026
Relay Therapeutics on May 19, 2026 reported initial Phase 2 ReInspire data for its PI3Kα mutant-selective inhibitor zovegalisib in PIK3CA-driven vascular anomalies, showing a 60% volumetric response rate at 12 weeks among 20 evaluable adults ...
Business Operations and StrategyProduct-Related Announcements
Relay Therapeutics advances zovegalisib combo in breast cancer
Positive
Apr 27, 2026
On April 27, 2026, Relay Therapeutics reported Phase 1/2 ReDiscover data for its triplet regimen of zovegalisib, atirmociclib and fulvestrant in heavily pre-treated, CDK4/6-experienced patients with PI3Kα-mutated, HR+/HER2- metastatic breast ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 23, 2026