Prokidney Corp. (PROK)
NASDAQ:PROK
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ProKidney
(NASDAQ:PROK)
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Rating:44Neutral
Price Target:
$1.50
▼(-9.64% Downside)
Action:Reiterated
Date:05/16/26
The score is held down primarily by very weak financial performance (minimal revenue, large losses, and heavy cash burn), reinforced by a technically weak downtrend (trading below all major moving averages with negative MACD). Offsetting factors are limited but include constructive corporate progress on the pivotal Phase 3 program and stated cash runway into mid-2027, while valuation support is minimal given the deeply negative P/E and no dividend.
Positive Factors
Regulatory alignment
FDA feedback confirming PROACT 1 could support accelerated and confirmatory approval and recognizing eGFR slope as a surrogate lowers regulatory uncertainty. This structural alignment shortens potential time-to-market if endpoints are met and improves planning for commercialization and payer discussions.
Negative Factors
Heavy cash burn
Persistent negative operating and free cash flow at this scale is structural for a clinical-stage biotech and necessitates recurring financing to fund R&D and manufacturing. Ongoing burn increases dilution risk, constrains strategic flexibility, and makes long-term planning contingent on capital markets or partnerships.
Read all positive and negative factors
Positive Factors
Negative Factors
Regulatory alignment
FDA feedback confirming PROACT 1 could support accelerated and confirmatory approval and recognizing eGFR slope as a surrogate lowers regulatory uncertainty. This structural alignment shortens potential time-to-market if endpoints are met and improves planning for commercialization and payer discussions.
Read all positive factors
ProKidney (PROK) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$528.43M
Dividend YieldN/A
Average Volume (3M)919.24K
Price to Earnings (P/E)―
Beta (1Y)2.16
Revenue Growth190.52%
EPS Growth12.60%
CountryUS
Employees204
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-0.55
Shares Outstanding141,987,950
10 Day Avg. Volume942,669
30 Day Avg. Volume919,237
Financial Highlights & Ratios
PEG Ratio0.27
Price to Book (P/B)-0.30
Price to Sales (P/S)335.98
P/FCF Ratio-2.22
Enterprise Value/Market Cap0.88
Enterprise Value/Revenue523.95
Enterprise Value/Gross Profit-233.48
Enterprise Value/Ebitda-2.99
Forecast
1Y Price Target
$5.42Price Target Upside226.20% Upside
Rating ConsensusHold
Number of Analyst Covering5
EPS Forecast (FY)-0.66
Revenue Forecast (FY)$408.00K
ProKidney Business Overview & Revenue Model
Company Description
ProKidney Corp., a clinical-stage biotechnology, engages in developing cellular therapy candidates. It is developing Renal Autologous Cell Therapy, an autologous homologous cell admixture that is in a Phase III development program, as well as Phas...
How the Company Makes Money
As a clinical-stage company, ProKidney’s ability to generate recurring product revenue depends on obtaining regulatory approval and commercializing its investigational therapies; product sales revenue is null. Historically, the company’s revenue h...
ProKidney Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
42
Neutral
Cash Flow
16
Very Negative
| Breakdown | TTM | Dec 2025 | Mar 2025 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 889.00K | 893.00K | 76.00K | 0.00 | 0.00 | 0.00 |
| Gross Profit | -2.00M | 893.00K | 76.00K | 0.00 | -3.04M | 0.00 |
| EBITDA | -155.68M | -144.62M | -158.49M | -125.59M | -143.99M | -53.12M |
| Net Income | -74.84M | -68.99M | -61.19M | -35.47M | -108.03M | -55.15M |
Balance Sheet | ||||||
| Total Assets | 292.78M | 335.57M | 441.07M | 420.55M | 518.00M | 40.30M |
| Cash, Cash Equivalents and Short-Term Investments | 224.94M | 270.02M | 358.29M | 362.95M | 490.25M | 20.56M |
| Total Debt | 3.78M | 2.96M | 3.24M | 4.41M | 2.40M | 1.33M |
| Total Liabilities | 29.68M | 34.78M | 39.44M | 29.22M | 13.06M | 13.38M |
| Stockholders Equity | -1.02B | -1.01B | -994.95M | -1.10B | -1.10B | 26.92M |
Cash Flow | ||||||
| Free Cash Flow | -150.06M | -135.31M | -155.86M | -124.27M | -78.94M | -55.49M |
| Operating Cash Flow | -132.21M | -120.12M | -126.35M | -90.07M | -77.09M | -50.30M |
| Investing Cash Flow | 110.50M | 103.97M | 20.41M | -329.98M | -1.74M | -5.19M |
| Financing Cash Flow | 25.80M | 25.57M | 144.41M | -9.55M | 548.52M | 71.47M |
ProKidney Technical Analysis
Neutral
1.66
Price Trends
1.88
Negative
2.03
Negative
2.30
Negative
Market Momentum
-0.07
Positive
45.70
Neutral
56.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PROK, the sentiment is Neutral. The current price of 1.66 is below the 20-day moving average (MA) of 1.79, below the 50-day MA of 1.88, and below the 200-day MA of 2.30, indicating a bearish trend. The MACD of -0.07 indicates Positive momentum. The RSI at 45.70 is Neutral, neither overbought nor oversold. The STOCH value of 56.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for PROK.
ProKidney Risk Analysis
ProKidney disclosed 91 risk factors in its most recent earnings report. ProKidney reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
ProKidney Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
53 Neutral | $312.95M | -4.91 | -58.82% | ― | ― | 29.97% | |
53 Neutral | $1.41B | -9.57 | 121.52% | ― | 52.92% | 13.32% | |
52 Neutral | $2.59B | -6.10 | -43.94% | ― | 39.04% | 29.88% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
50 Neutral | $903.63M | -7.50 | 39.24% | ― | 150.30% | 59.74% | |
46 Neutral | $1.81B | -5.04 | -64.21% | ― | 27.23% | -12.53% | |
44 Neutral | $528.43M | -2.81 | 7.40% | ― | 190.52% | 12.60% |
* Healthcare Sector Average
PROK
ProKidney
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1.02
139.73%
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ProKidney Corporate Events
Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
ProKidney Highlights Progress in Pivotal Phase 3 CKD Trial
Positive
May 15, 2026
On May 15, 2026, ProKidney reported first-quarter 2026 results and business updates, highlighting progress in its pivotal Phase 3 REGEN-006 (PROACT 1) trial of rilparencel for advanced CKD in patients with diabetes. The company said enrollment for...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.