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Rezolute (RZLT)
NASDAQ:RZLT

Rezolute (RZLT) AI Stock Analysis

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RZLT

Rezolute

(NASDAQ:RZLT)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
$3.00
▲(0.33% Upside)
Action:ReiteratedDate:03/14/26
The score is held down primarily by weak financial performance (no revenue, widening losses, and heavy cash burn) and a bearish technical setup (price below major moving averages with negative MACD). Valuation provides limited support due to negative earnings and no dividend, while the latest corporate update adds uncertainty after a Phase 3 miss despite some encouraging secondary observations and regulatory planning.
Positive Factors
Balance Sheet Strength
Very low leverage (~0.01 debt-to-equity) combined with sizable assets (~$139M TTM) gives Rezolute structural financial flexibility. This supports continued R&D and regulatory activities over the next several months, reducing near-term solvency risk while management pursues regulatory options.
Negative Factors
Pre‑Revenue Status
Rezolute has reported no product revenue, meaning it lacks commercial cash inflows and real-world market validation. Over a multi‑month horizon this forces continued reliance on external capital, prevents self‑funding of development, and delays assessment of pricing and demand dynamics.
Read all positive and negative factors
Positive Factors
Negative Factors
Balance Sheet Strength
Very low leverage (~0.01 debt-to-equity) combined with sizable assets (~$139M TTM) gives Rezolute structural financial flexibility. This supports continued R&D and regulatory activities over the next several months, reducing near-term solvency risk while management pursues regulatory options.
Read all positive factors

Rezolute (RZLT) vs. SPDR S&P 500 ETF (SPY)

Rezolute Business Overview & Revenue Model

Company Description
Rezolute, Inc., a clinical stage biopharmaceutical company, develops transformative therapies for metabolic diseases associated with chronic glucose imbalance in the United States. The company's lead product candidate is RZ358, a human monoclonal ...
How the Company Makes Money
As a clinical-stage biopharmaceutical company, Rezolute has not historically generated meaningful recurring revenue from product sales; its operations are primarily funded through external financing rather than commercial income. The company’s pot...

Rezolute Financial Statement Overview

Summary
Financial profile is weak overall: the company remains pre-revenue with materially widening net losses (to about -$84.2M TTM) and deteriorating operating/free cash flow (about -$77.1M TTM). The balance sheet is a relative bright spot with very low leverage (debt-to-equity ~0.01) and sizable assets, but persistent losses imply ongoing funding/runway risk.
Income Statement
12
Very Negative
Balance Sheet
68
Positive
Cash Flow
18
Very Negative
BreakdownTTMJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-15.00K0.000.000.000.00-13.00K
EBITDA-88.21M-79.86M-70.39M-55.96M-39.24M-20.51M
Net Income-84.23M-74.41M-68.46M-51.79M-41.06M-20.90M
Balance Sheet
Total Assets138.63M175.49M132.74M123.72M152.42M42.61M
Cash, Cash Equivalents and Short-Term Investments132.94M167.86M126.87M101.90M150.41M41.05M
Total Debt1.28M1.61M2.23M2.48M188.00K14.42M
Total Liabilities10.63M13.36M11.73M7.55M2.95M16.51M
Stockholders Equity128.00M162.13M121.00M116.17M149.47M26.10M
Cash Flow
Free Cash Flow-77.15M-69.08M-57.37M-44.63M-39.62M-20.44M
Operating Cash Flow-77.15M-69.08M-57.37M-44.48M-39.62M-20.44M
Investing Cash Flow-22.28M-14.54M48.70M-101.46M0.000.00
Financing Cash Flow102.44M107.33M63.03M11.57M148.98M51.53M

Rezolute Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2.99
Price Trends
50DMA
3.12
Negative
100DMA
4.71
Negative
200DMA
5.80
Negative
Market Momentum
MACD
-0.09
Negative
RSI
50.46
Neutral
STOCH
62.04
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RZLT, the sentiment is Neutral. The current price of 2.99 is above the 20-day moving average (MA) of 2.90, below the 50-day MA of 3.12, and below the 200-day MA of 5.80, indicating a neutral trend. The MACD of -0.09 indicates Negative momentum. The RSI at 50.46 is Neutral, neither overbought nor oversold. The STOCH value of 62.04 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for RZLT.

Rezolute Risk Analysis

Rezolute disclosed 31 risk factors in its most recent earnings report. Rezolute reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rezolute Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$896.76M-10.26-34.23%522.13%62.68%
54
Neutral
$2.26B-3.52-246.19%-12.93%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.17B-16.13-56.64%-36.36%-945.72%
48
Neutral
$838.60M-27.51-42.39%116.64%47.93%
44
Neutral
$286.14M-2.69-64.81%26.65%
43
Neutral
$837.53M-14.58%38.16%48.43%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RZLT
Rezolute
2.99
0.09
3.10%
GERN
Geron
1.40
-0.19
-11.95%
ABUS
Arbutus Biopharma
4.29
0.80
22.92%
XNCR
Xencor
11.42
0.78
7.33%
KOD
Kodiak Sciences
37.00
34.20
1221.43%
TSHA
Taysha Gene Therapies
4.07
2.68
192.81%

Rezolute Corporate Events

Business Operations and StrategyRegulatory Filings and Compliance
Rezolute Prepares FDA Submission After sunRIZE Trial Review
Neutral
Mar 24, 2026
On March 24, 2026, Rezolute reported outcomes from a March 17 in-person Type B FDA meeting regarding sunRIZE, its Phase 3 trial of ersodetug in congenital hyperinsulinism, after the study previously failed to meet its primary endpoint in December ...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Rezolute Updates sunRIZE Phase 3 Trial and FDA Plans
Negative
Jan 7, 2026
On January 7, 2025, Rezolute reported detailed observations from its Phase 3 sunRIZE trial in congenital hyperinsulinism, noting that although the study did not meet its primary and key secondary endpoints for reducing hypoglycemia events and time...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 14, 2026