Diamedica Therapeutics (DMAC) AI Stock Analysis

• Market Cap: $447.87M
• Dividend Yield: N/A
• Average Volume (3M): 350.44K
• Price to Earnings (P/E): ―
• Beta (1Y): 1.52
• Revenue Growth: N/A
• EPS Growth: -29.73%
• Country: US
• Employees: 27
• Sector: Healthcare
• Sector Strength: 45
• Industry: Biotechnology
• EPS (TTM): -0.17
• Shares Outstanding: 52,077,440
• 10 Day Avg. Volume: 182,202
• 30 Day Avg. Volume: 350,444
• PEG Ratio: 0.00
• Price to Book (P/B): 5.39
• Price to Sales (P/S): 0.00
• P/FCF Ratio: -9.93
• Enterprise Value/Market Cap: 0.64
• Enterprise Value/Revenue: N/A
• Enterprise Value/Gross Profit: -9.86K
• Enterprise Value/Ebitda: -8.77
• 1Y Price Target: $17.00
• Price Target Upside: 97.67% Upside
• Rating Consensus: Strong Buy
• Number of Analyst Covering: 5
• EPS Forecast (FY): -0.75
• Revenue Forecast (FY): N/A

• Rating: 49 Neutral
• Price Target: $8.00 ▼(-6.98% Downside)

The score is held back primarily by pre-revenue financial performance—widening losses and increasing cash burn—despite a low-debt balance sheet. Earnings-call updates provide some support via positive clinical signals and strengthened liquidity, while technical indicators are mixed and valuation metrics offer limited help given ongoing losses and no dividend.

Positive Factors

Clinical Progress

The advancement in the preeclampsia program with DM199 highlights potential for new treatments in a field with unmet needs, strengthening DiaMedica's pipeline.

Financial Runway

A strong financial position ensures DiaMedica can continue its R&D efforts and clinical trials without immediate funding pressure, supporting long-term project viability.

Board Appointment

The addition of an experienced board member can enhance strategic decision-making and potentially facilitate partnerships or acquisitions, benefiting long-term growth.

Negative Factors

Zero Revenue

The absence of revenue underscores the company's reliance on successful clinical outcomes and partnerships, posing a risk to financial sustainability if milestones are not met.

Increasing Net Losses

Rising net losses highlight financial strain and the need for successful product commercialization to offset costs, challenging long-term profitability.

R&D Expense Growth

Increased R&D expenses reflect ongoing investment in clinical trials but also strain financial resources, necessitating future revenue generation to sustain operations.

Diamedica Therapeutics Business Overview & Revenue Model

Company Description

DiaMedica Therapeutics Inc., a clinical stage biopharmaceutical company, develops treatments for neurological and kidney diseases. The company's lead drug candidate is DM199, a recombinant human tissue kallikrein-1 protein, which is in Phase 2 REDUX trial for the treatment of patients with moderate or severe chronic kidney disease caused by Type I or Type II diabetes; and Phase 2/3 REMEDY2 trials for the treatment of patients with acute ischemic stroke. It is also developing DM300 that is in pre-clinical stage for the treatment of inflammatory diseases. The company was formerly known as DiaMedica Inc. and changed its name to DiaMedica Therapeutics Inc. in December 2016. DiaMedica Therapeutics Inc. was incorporated in 2000 and is headquartered in Minneapolis, Minnesota.

How the Company Makes Money

Diamedica Therapeutics generates revenue primarily through strategic partnerships, collaborations, and licensing agreements with larger pharmaceutical companies. These arrangements often include upfront payments, milestone payments based on the achievement of certain development or regulatory goals, and royalties on future sales of successfully commercialized products. The company also seeks funding through public and private financing to support its research and development efforts, which is crucial for advancing its pipeline candidates through clinical trials.

Diamedica Therapeutics Financial Statement Overview

Summary

Diamedica Therapeutics, operating in the biotechnology sector, exhibits typical financial characteristics of a company in the development phase. The absence of revenue coupled with increasing net losses highlights the need for successful product development and eventual commercialization. While the balance sheet shows low leverage, diminishing cash reserves could pose a risk to its operational sustainability without additional funding. The firm's reliance on external financing to support negative cash flows underscores the challenges in achieving financial independence.

Income Statement

Diamedica Therapeutics has consistently reported zero revenue, reflecting its developmental stage focus typical in the biotechnology industry. The company incurred significant net losses over the years, with a noticeably increasing net loss from $13.6M in 2022 to $24.4M in 2024. The lack of revenue growth and persistent negative net income are significant concerns.

Balance Sheet

The company's balance sheet shows a high equity ratio, with stockholders' equity consistently making up a significant portion of total assets (87.9% in 2024). The debt-to-equity ratio remains low, indicating limited leverage, which is positive. However, declining total assets from $54.2M in 2023 to $46.3M in 2024, alongside decreasing cash reserves, may constrain future financial flexibility.

Cash Flow

Diamedica's cash flow situation highlights ongoing operational cash outflows, with operating cash flow deteriorating from -$18.7M in 2023 to -$22.1M in 2024. Free cash flow has also been negative, reflecting the cash burn typical in biotech firms without commercial products. The company relies heavily on financing activities to support its cash flow needs, which may not be sustainable long-term.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	0.00	0.00	0.00	0.00	0.00	0.00
Gross Profit	-29.00K	0.00	0.00	0.00	0.00	0.00
EBITDA	-32.61M	-26.64M	-21.24M	-13.98M	-13.62M	-12.68M
Net Income	-31.93M	-24.44M	-19.38M	-13.68M	-13.59M	-12.29M
Balance Sheet
Total Assets	57.05M	46.34M	54.16M	34.40M	45.55M	28.09M
Cash, Cash Equivalents and Short-Term Investments	55.32M	44.15M	52.90M	33.50M	45.11M	27.51M
Total Debt	266.00K	340.00K	400.00K	469.00K	52.00K	118.00K
Total Liabilities	5.42M	5.63M	3.10M	2.57M	1.53M	2.08M
Stockholders Equity	51.62M	40.72M	51.06M	31.83M	44.02M	26.01M
Cash Flow
Free Cash Flow	-27.83M	-22.10M	-18.75M	-11.59M	-12.27M	-9.23M
Operating Cash Flow	-27.79M	-22.08M	-18.73M	-11.51M	-12.25M	-9.19M
Investing Cash Flow	-5.42M	8.56M	-18.30M	11.54M	-20.54M	-16.13M
Financing Cash Flow	32.38M	11.99M	36.84M	-6.00K	30.09M	28.84M

Diamedica Therapeutics Technical Analysis

• Technical Analysis Sentiment: Positive
• Last Price: 8.60
• 50DMA: Positive
• 100DMA: Positive
• 200DMA: Positive
• MACD: Positive
• RSI: Neutral
• STOCH: Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DMAC, the sentiment is Positive. The current price of 8.6 is above the 20-day moving average (MA) of 8.31, above the 50-day MA of 7.95, and above the 200-day MA of 5.76, indicating a bullish trend. The MACD of 0.07 indicates Positive momentum. The RSI at 55.20 is Neutral, neither overbought nor oversold. The STOCH value of 70.70 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DMAC.

Diamedica Therapeutics Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
CAPR	57 Neutral	$1.35B	―	-107.79%	―	-52.08%	-69.35%
ANNX	56 Neutral	$966.79M	-4.38	-83.98%	―	―	-35.62%
RCKT	52 Neutral	$428.56M	-1.65	-74.88%	―	―	18.39%
Sector *	51 Neutral	$7.86B	-0.30	-43.30%	2.27%	22.53%	-2.21%
DMAC	49 Neutral	$447.87M	-11.91	-64.12%	―	―	-29.73%
BNTC	48 Neutral	$410.75M	-11.65	-43.71%	―	―	80.95%
TVRD	38 Underperform	$43.44M	-0.46	-97.61%	―	-53.67%	86.75%

Diamedica Therapeutics Corporate Events

DiaMedica Therapeutics Raises Capital via Share Offering

On December 19, 2025, DiaMedica Therapeutics Inc. sold 1,501,000 common shares to a healthcare institutional fund at a price of $8.10 per share in a block transaction conducted under its at-the-market offering program, generating $12.2 million in gross proceeds before fees and expenses. The capital raise strengthens the company’s financial position and provides additional funding flexibility for its ongoing operations and development activities, potentially supporting its strategic initiatives in the biopharmaceutical market.

The most recent analyst rating on (DMAC) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on Diamedica Therapeutics stock, see the DMAC Stock Forecast page.