Development RisksRP2 is being developed in uveal melanoma and hepatocellular carcinoma, with new trials enrolling patients and expanding its research scope.
Market CompetitionReplimune's RP1 + Opdivo combination therapy shows potential differentiation against other treatments like Amtagvi™ due to its efficacy and safety profile.
Regulatory UncertaintyThe FDA has accepted REPL's BLA for RP1 and granted priority review, with a PDUFA date set for July 22, 2025.