Early Biomarker EvidenceEarly biomarker changes reported in the MoDE and TRAP programs are unlikely to be spontaneous and support biological activity that could reduce clinical development risk for those assets.
Lead Asset PotentialBHV-1400 targets the abnormal IgA protein driving IgA nephropathy and could act as a best-in-class degrader that permits chronic treatment while avoiding broad immunosuppression.
Strategic Portfolio FocusManagement is concentrating resources on immunology, obesity, and epilepsy and implementing cost optimization to preserve cash and advance higher‑value late stage programs.