Pharmacokinetics And Dose EscalationMuscle tissue measurements confirmed robust drug accumulation consistent with the pharmacokinetic model, supporting the potential for higher doses to increase target engagement.
Safety ProfileSafety data reported no serious adverse events, no kidney-related treatment-emergent adverse events, and no cumulative albumin signal across doses, supporting tolerability of the program.
Trial Execution And FinancingManagement reiterated sufficient financial runway and indicated that higher-dose cohorts can be recruited and dosed at ex‑US sites, supporting completion of key readouts and preserving trial timelines.