Competitive LandscapeInvestors are waiting for human proof-of-concept before committing, especially as the competitive landscape for in vivo programs intensifies with companies like Beam and CRISPR entering the space.
Human Proof-of-ConceptInvestors are awaiting human proof-of-concept before buying in, especially given that the in vivo competitive landscape continues to heat up.
Workforce ReductionA 65% reduction in force reflects the company's reprioritization efforts, which also led to the discontinuation of the reni-cel program as a commercial search failed to yield a partner.