Gene Editing InnovationEditas has nominated EDIT-401, an in vivo gene editor, to be used in the treatment of atherosclerotic cardiovascular disease and heterozygous familial hypercholesterolemia, showing promising preclinical data with ~90% reduction in LDL-C.
Preclinical SuccessEDIT-401 demonstrated a ~90% mean LDL-C reduction in animal models, showcasing its potential efficacy and safety with no concerning adverse events.
Strategic PositioningEditas' pivot to cardiovascular disease could better position the company as a takeout target given the recent acquisition deals in the cardiovascular disease space for gene editing companies.