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PRME Stock Chart & Stats
$3.81
-$0.14(-4.27%)
At close: 4:00 PM EST
$3.81
-$0.14(-4.27%)
Day’s Range― - ―
52-Week Range$2.02 - $6.94
Previous CloseN/A
Volume144.88K
Average Volume (3M)2.91M
Market Cap
$698.99M
Enterprise Value$621.16M
Total Cash (Recent Filing)$135.50M
Total Debt (Recent Filing)$114.51M
Price to Earnings (P/E)―
Beta2.82
Next Earnings
Aug 06, 2026EPS Estimate
-0.26Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-1.27
Shares Outstanding180,617,450
10 Day Avg. Volume2,883,124
30 Day Avg. Volume2,909,180
Financial Highlights & Ratios
PEG Ratio0.14
Price to Book (P/B)4.27
Price to Sales (P/S)111.44
P/FCF Ratio-3.09
Enterprise Value/Market Cap0.89
Enterprise Value/Revenue153.98
Enterprise Value/Gross Profit-14.22
Enterprise Value/Ebitda-3.25
Forecast
1Y Price Target
$7.83Price Target Upside105.60% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering8
EPS Forecast (FY)-1
Revenue Forecast (FY)$12.83M
Bulls Say, Bears Say
Bulls Say
Proprietary Prime Editing PlatformA proprietary prime editing platform is a durable competitive asset: it creates a technology moat and repeated application across multiple disease targets (liver, blood, etc.). Platform-based R&D supports long-term pipeline scalability and potential recurring licensing or royalty income if clinical success follows.
Collaboration And Licensing Revenue ModelReliance on collaborations and licensing provides non-dilutive funding streams and milestone-driven capital that can extend runway without immediate product sales. This model supports continued R&D investment and aligns incentives with partners, offering sustainable funding optionality over months to years.
Experienced CFO And Governance ContinuityAdding a veteran biotech finance executive and reaffirming directors/auditor strengthens financial governance and strategic oversight. Clear separation of CFO from CEO improves financial control and credibility with investors and partners, reducing execution risk on funding and partnerships over the medium term.
Bears Say
Rising Leverage And Shrinking EquityHigher leverage and falling equity reduce financial flexibility for an R&D-stage biotech that depends on external funding. Elevated debt magnifies refinancing and covenant risk, constraining strategic options and increasing dilution or costly financing likelihood if clinical progress or partner funding slows.
Weak Cash Generation And High Burn RateConsistent large operating and free-cash outflows indicate the company is burning cash to fund R&D. Persistent negative cash generation shortens runway absent new deals or financing, elevating reliance on milestone payments or capital raises that can dilute shareholders and disrupt long-term program continuity.
Declining Revenue And Deeply Negative MarginsFalling revenue alongside outsized operating losses shows the cost base is far ahead of commercialization scale. Structural negative margins increase dependence on external funding and indicate the company has not yet converted R&D into sustainable commercial cash flows, heightening execution and financing risk.
PRME FAQ
What was Prime Medicine, Inc.’s price range in the past 12 months?
Prime Medicine, Inc. lowest stock price was $2.02 and its highest was $6.94 in the past 12 months.
What is Prime Medicine, Inc.’s market cap?
Prime Medicine, Inc.’s market cap is $698.99M.
When is Prime Medicine, Inc.’s upcoming earnings report date?
Prime Medicine, Inc.’s upcoming earnings report date is Aug 06, 2026 which is in 31 days.
How were Prime Medicine, Inc.’s earnings last quarter?
Prime Medicine, Inc. released its earnings results on May 07, 2026. The company reported -$0.28 earnings per share for the quarter, missing the consensus estimate of -$0.251 by -$0.029.
Is Prime Medicine, Inc. overvalued?
According to Wall Street analysts Prime Medicine, Inc.’s price is currently Undervalued.
Does Prime Medicine, Inc. pay dividends?
Prime Medicine, Inc. pays a Quarterly dividend of $0.8 which represents an annual dividend yield of N/A. See more information on Prime Medicine, Inc. dividends here
What is Prime Medicine, Inc.’s EPS estimate?
Prime Medicine, Inc.’s EPS estimate is -0.26.
How many shares outstanding does Prime Medicine, Inc. have?
Prime Medicine, Inc. has 180,617,450 shares outstanding.
What happened to Prime Medicine, Inc.’s price movement after its last earnings report?
Prime Medicine, Inc. reported an EPS of -$0.28 in its last earnings report, missing expectations of -$0.251. Following the earnings report the stock price went down -8.651%.
Which hedge fund is a major shareholder of Prime Medicine, Inc.?
Currently, no hedge funds are holding shares in PRME
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Prime Medicine, Inc. Stock Smart Score
Outperform
1
2
3
4
5
6
7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
$7.83 (105.60% Upside)
$7.83 (105.60% Upside)
Blogger Sentiment
Bullish
PRME Sentiment 70%
Sector Average 69%
Sector Average 69%
Hedge Fund Trend
Increased
By 780.1K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Very Positive
Last 7 Days ▼ 0.6%
Last 30 Days ▲ 16.8%
Last 30 Days ▲ 16.8%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Negative
20 days / 200 days
Momentum
26.05%
12-Months-Change
Fundamentals
Return on Equity
-188.82%
Trailing 12-Months
Asset Growth
-10.19%
Trailing 12-Months
Company Description
Prime Medicine, Inc.
Prime Medicine, Inc. operates as a biotechnology firm, dedicated to delivering genetic therapies for various diseases by strategically employing advanced gene editing technology. Central to their platform is the "Prime Editor" system, which combines a unique Prime Editor protein—a hybrid composed of a Cas protein and a reverse transcriptase enzyme—with a specialized pegRNA molecule. This pegRNA plays a crucial role by both guiding the Prime Editor to a precise location within the genome and providing the essential template for introducing the desired modification to the target DNA sequence. The company, founded in 2019, maintains its headquarters in Cambridge, Massachusetts.
PRME Stock 12 Month Forecast
Average Price Target
$7.83
▲(105.60% Upside)
Technical Analysis
Immatics
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Relay Therapeutics
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Taysha Gene Therapies
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Sana Biotechnology
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Upstream Bio, Inc.
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Ownership Overview
35.58% Insiders
7.24% Mutual Funds
0.20% Other Institutional Investors
44.17% Public Companies and
Individual Investors












