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Otsuka Holdings Co Ltd (OTSKY)
OTHER OTC:OTSKY
US Market

Otsuka Holdings Co (OTSKY) AI Stock Analysis

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OTSKY

Otsuka Holdings Co

(OTC:OTSKY)

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Outperform 75 (OpenAI - 5.2)
Rating:75Outperform
Price Target:
$39.00
▲(31.36% Upside)
Action:ReiteratedDate:02/18/26
The score is driven primarily by strong financial performance (revenue growth, profit rebound, improving free cash flow, and low leverage). Valuation is reasonable at a mid-teens P/E with a modest dividend yield. Offsetting these positives, technical indicators suggest the stock is extended/overbought (high RSI and Stoch), which raises near-term downside risk.
Positive Factors
Consistent revenue growth
Sustained top-line growth from ¥1.42T to ¥2.59T over 2020–2025 indicates durable market demand and successful product commercialization. Steady revenue expansion supports reinvestment in R&D and global commercialization, underpinning longer-term earnings power and strategic flexibility.
Negative Factors
Margin pressure/volatility
Profitability has rebounded, but margins remain below 2020 peaks, signaling structural pressures such as mix shifts, pricing or cost increases. Persistent margin variability can limit operating leverage benefits from revenue growth and constrain long-term free cash flow expansion if not addressed.
Read all positive and negative factors
Positive Factors
Negative Factors
Consistent revenue growth
Sustained top-line growth from ¥1.42T to ¥2.59T over 2020–2025 indicates durable market demand and successful product commercialization. Steady revenue expansion supports reinvestment in R&D and global commercialization, underpinning longer-term earnings power and strategic flexibility.
Read all positive factors

Otsuka Holdings Co (OTSKY) vs. SPDR S&P 500 ETF (SPY)

Otsuka Holdings Co Business Overview & Revenue Model

Company Description
Otsuka Holdings Co., Ltd. engages in pharmaceuticals, nutraceuticals, consumer products, and other businesses worldwide. The company develops pharmaceutical products in the fields of oncology, cardiovascular system, renal system, digestive system,...
How the Company Makes Money
Otsuka Holdings generates revenue primarily through the sale of pharmaceutical products, which account for a significant portion of its income. The company markets a range of prescription drugs, with a strong focus on areas such as psychiatry, neu...

Otsuka Holdings Co Earnings Call Summary

Earnings Call Date:Aug 01, 2024
(Q2-2024)
|
% Change Since: |
Next Earnings Date:Apr 28, 2026
Earnings Call Sentiment Positive
The earnings call presented a strong overall performance in both pharmaceutical and nutraceutical segments with significant revenue and profit growth, and positive strategic expansions such as the acquisition for drug discovery. However, there were challenges such as impairment losses and increased SG&A expenses.
Positive Updates
Significant Revenue and Profit Growth
Revenue increased by 17.0% to JPY 1,108.9 billion, and business profit grew by 37.8% to JPY 213.6 billion year-on-year, highlighting strong performance in pharmaceutical and nutraceutical segments.
Negative Updates
Impairment Loss Impact
Operating profit was impacted by an impairment loss on AVP-786, which led to strategic discontinuation of its development.
Read all updates
Q2-2024 Updates
Negative
Significant Revenue and Profit Growth
Revenue increased by 17.0% to JPY 1,108.9 billion, and business profit grew by 37.8% to JPY 213.6 billion year-on-year, highlighting strong performance in pharmaceutical and nutraceutical segments.
Read all positive updates
Company Guidance
During the Q2 2024 earnings call for 4578.T, significant financial growth was highlighted, with revenue increasing by 17.0% to JPY 1,108.9 billion and business profit rising by 37.8% to JPY 213.6 billion year-on-year, driven by strong performance in pharmaceutical and nutraceutical segments. Despite an impairment loss on AVP-786 affecting operating profit, net profit climbed by 5.1% due to finance income. The pharmaceutical business saw revenue increase by 17.9% to JPY 766.7 billion, bolstered by products like ABILIFY MAINTENA and JYNARQUE, while LONSURF achieved significant gains through colorectal cancer treatment guidelines endorsements. Nutraceuticals experienced over 20% growth, with revenue reaching JPY 271.8 billion, fueled by a 56.9% rise in the For Women's Health category. The company revised its full-year forecast, raising revenue expectations by JPY 175 billion to JPY 2,315 billion and business profit projections by JPY 60 billion to JPY 390 billion, aiming to maintain momentum through strategic investments and addressing social issues.

Otsuka Holdings Co Financial Statement Overview

Summary
Strong overall fundamentals: consistent revenue growth through 2025, a meaningful profit rebound in 2024–2025, improving free cash flow, and a conservatively leveraged balance sheet. Key watch items are margin volatility versus 2020 levels and higher total debt in 2025 (though leverage remains low).
Income Statement
78
Positive
Balance Sheet
86
Very Positive
Cash Flow
80
Positive
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.59T2.33T2.02T1.74T1.50T
Gross Profit1.86T1.67T1.41T1.17T1.00T
EBITDA554.23B452.62B246.96B279.83B231.43B
Net Income380.76B343.12B121.62B133.91B125.46B
Balance Sheet
Total Assets4.20T3.74T3.36T3.10T2.82T
Cash, Cash Equivalents and Short-Term Investments535.01B458.08B529.40B489.12B430.76B
Total Debt307.25B189.38B214.19B194.16B212.45B
Total Liabilities1.10T961.09B924.93B840.17B775.73B
Stockholders Equity3.04T2.73T2.39T2.23T2.01T
Cash Flow
Free Cash Flow331.04B225.28B168.56B104.06B115.71B
Operating Cash Flow423.14B354.64B283.23B211.85B228.86B
Investing Cash Flow-169.42B-265.79B-190.54B-81.58B-95.29B
Financing Cash Flow-144.00B-189.37B-60.26B-95.47B-95.84B

Otsuka Holdings Co Technical Analysis

Technical Analysis Sentiment
Positive
Last Price29.69
Price Trends
50DMA
33.23
Positive
100DMA
31.01
Positive
200DMA
28.57
Positive
Market Momentum
MACD
0.41
Positive
RSI
45.65
Neutral
STOCH
5.77
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OTSKY, the sentiment is Positive. The current price of 29.69 is below the 20-day moving average (MA) of 34.57, below the 50-day MA of 33.23, and above the 200-day MA of 28.57, indicating a neutral trend. The MACD of 0.41 indicates Positive momentum. The RSI at 45.65 is Neutral, neither overbought nor oversold. The STOCH value of 5.77 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for OTSKY.

Otsuka Holdings Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
$35.28B12.3712.90%1.48%7.51%203.70%
74
Outperform
$176.37B17.9441.01%2.52%2.51%1682.88%
71
Outperform
$119.69B15.6139.27%4.11%-0.22%
69
Neutral
$113.22B-31.4214.71%4.58%-9.32%120.62%
67
Neutral
$116.98B13.1937.19%3.41%7.51%132.14%
64
Neutral
$25.38B19.967.28%5.00%-1.03%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OTSKY
Otsuka Holdings Co
33.47
10.05
42.92%
BIIB
Biogen
172.97
57.80
50.19%
BMY
Bristol-Myers Squibb
58.62
10.32
21.38%
GILD
Gilead Sciences
138.99
38.05
37.69%
GSK
GlaxoSmithKline
58.21
24.90
74.74%
SNY
Sanofi
46.76
-3.15
-6.31%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 18, 2026