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Otsuka Holdings Co Ltd (OTSKY)
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Otsuka Holdings Co (OTSKY) AI Stock Analysis

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OTSKY

Otsuka Holdings Co

(OTC:OTSKY)

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Outperform 74 (OpenAI - 4o)
Rating:74Outperform
Price Target:
$30.00
▲(9.77% Upside)
Otsuka Holdings Co's strong financial performance, characterized by robust revenue and profit growth, efficient operations, and effective cash flow management, is the most significant factor contributing to its score. The valuation suggests potential undervaluation, offering an attractive entry point for investors. Technical analysis indicates stability but lacks strong momentum, which slightly tempers the overall score.

Otsuka Holdings Co (OTSKY) vs. SPDR S&P 500 ETF (SPY)

Otsuka Holdings Co Business Overview & Revenue Model

Company DescriptionOtsuka Holdings Co., Ltd. engages in pharmaceuticals, nutraceuticals, consumer products, and other businesses worldwide. The company develops pharmaceutical products in the fields of oncology, cardiovascular system, renal system, digestive system, ophthalmology, diagnostics, and intravenous solutions, as well as medical devices businesses. It also provides EQUELLE, a product for women's health and beauty; BODYMAINTÉ Jelly, a conditioning food product; BODYMAINTÉ Drink, a drinkable-liquid; POCARI SWEAT, a drink; Calorie Mate, a nutritional food; OS-1, an oral rehydration solution; HINEX-R, a concentrated liquid diet; and Oronine H Ointment, a household antiseptic medicine. In addition, the company offers soft drinks, food products, and wines; chemicals; clinical testing and medical equipment; cosmetics; warehousing and transport services; analysis and measurement equipment; pharmaceutical intermediates; vehicle headlight testers; synthetic resin molded products; paper products; artificial turf; ceramic boards, ceramic walls, reliefs, terracotta, OT ceramics, and ceramic portraits and sign boards; functional films; stable isotopes; software and services to enhance management of mental healthcare systems; potassium titanate; polyolefin foams; spring and mineral water; industrial chemicals; hydrazine; insecticide and toiletry products; and adhesive tapes. Further, it operates a hotel. Otsuka Holdings Co., Ltd. was founded in 1921 and is based in Tokyo, Japan.
How the Company Makes MoneyOtsuka Holdings generates revenue primarily through its pharmaceutical division, which offers prescription medications for various health conditions, leading to substantial sales from drug formulations, particularly in psychiatry and neurology. This segment is bolstered by ongoing research and development initiatives, resulting in new drug approvals and market expansions. Additionally, the company's consumer health division contributes significantly to its earnings through the sale of nutraceuticals and functional beverages, supported by brand strength and effective marketing strategies. Otsuka also engages in strategic partnerships and collaborations with other pharmaceutical companies for joint ventures, research efforts, and marketing, enhancing its revenue potential. Overall, the company's diverse portfolio and commitment to innovation help sustain its financial growth.

Otsuka Holdings Co Earnings Call Summary

Earnings Call Date:Oct 31, 2025
(Q2-2024)
|
% Change Since: |
Next Earnings Date:Feb 13, 2026
Earnings Call Sentiment Positive
The earnings call presented a strong overall performance in both pharmaceutical and nutraceutical segments with significant revenue and profit growth, and positive strategic expansions such as the acquisition for drug discovery. However, there were challenges such as impairment losses and increased SG&A expenses.
Q2-2024 Updates
Positive Updates
Significant Revenue and Profit Growth
Revenue increased by 17.0% to JPY 1,108.9 billion, and business profit grew by 37.8% to JPY 213.6 billion year-on-year, highlighting strong performance in pharmaceutical and nutraceutical segments.
Nutraceutical Business Expansion
The Nutraceutical business achieved over 20% growth, with revenue increasing in all three categories, notably For Women's Health at 56.9% and For Healthier Life at 25.5%.
Pharmaceutical Business Growth
Revenue in the pharmaceutical business increased by 17.9% year-on-year to JPY 766.7 billion, with significant contributions from products like REXULTI and LONSURF.
Upward Revision of Financial Forecast
The full-year revenue forecast was revised up by JPY 175 billion to JPY 2,315 billion, and business profit was revised up by JPY 60 billion to JPY 390 billion.
Acquisition for Drug Discovery
Announcement of the acquisition of a company in Boston for drug discovery technology, indicating strategic expansion.
Negative Updates
Impairment Loss Impact
Operating profit was impacted by an impairment loss on AVP-786, which led to strategic discontinuation of its development.
Decrease in Milestone Revenue
Upfront milestone and royalty revenue decreased to JPY 41.8 billion due to lower sales milestone income compared to the previous year.
Increase in SG&A Expenses
SG&A expenses increased due to higher promotion expenses, impacting overall cost management.
Company Guidance
During the Q2 2024 earnings call for 4578.T, significant financial growth was highlighted, with revenue increasing by 17.0% to JPY 1,108.9 billion and business profit rising by 37.8% to JPY 213.6 billion year-on-year, driven by strong performance in pharmaceutical and nutraceutical segments. Despite an impairment loss on AVP-786 affecting operating profit, net profit climbed by 5.1% due to finance income. The pharmaceutical business saw revenue increase by 17.9% to JPY 766.7 billion, bolstered by products like ABILIFY MAINTENA and JYNARQUE, while LONSURF achieved significant gains through colorectal cancer treatment guidelines endorsements. Nutraceuticals experienced over 20% growth, with revenue reaching JPY 271.8 billion, fueled by a 56.9% rise in the For Women's Health category. The company revised its full-year forecast, raising revenue expectations by JPY 175 billion to JPY 2,315 billion and business profit projections by JPY 60 billion to JPY 390 billion, aiming to maintain momentum through strategic investments and addressing social issues.

Otsuka Holdings Co Financial Statement Overview

Summary
Otsuka Holdings Co presents a strong financial profile with impressive revenue and profit growth, efficient operations, and a stable balance sheet. The company demonstrates effective cash flow management, supporting its growth and operational efficiency. While the financial statements reflect a positive outlook, continued monitoring of leverage and cash flow sustainability is advised to maintain financial health.
Income Statement
85
Very Positive
Otsuka Holdings Co has demonstrated strong revenue growth with a TTM growth rate of 35.6%, indicating robust expansion. The company maintains high profitability with a gross profit margin of 72.12% and a net profit margin of 17.02% in the TTM period. EBIT and EBITDA margins are also healthy at 16.89% and 21.46%, respectively, reflecting efficient operations. Overall, the income statement shows a positive trajectory with strong growth and profitability.
Balance Sheet
78
Positive
The balance sheet of Otsuka Holdings Co is stable, with a low debt-to-equity ratio of 0.0777, indicating conservative leverage. The return on equity is strong at 15.41%, showcasing effective use of equity to generate profits. The equity ratio stands at 71.85%, suggesting a solid capital structure. The company has managed to maintain a healthy balance between debt and equity, supporting its financial stability.
Cash Flow
82
Very Positive
Otsuka Holdings Co exhibits strong cash flow performance with a significant free cash flow growth rate of 382.6% in the TTM period. The operating cash flow to net income ratio is 0.64, indicating efficient cash generation relative to net income. The free cash flow to net income ratio is 0.78, reflecting strong cash conversion. Overall, the cash flow statement highlights robust cash generation and growth.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.40T2.33T2.02T1.74T1.50T1.42T
Gross Profit1.73T1.67T1.41T1.17T1.00T983.08B
EBITDA536.85B452.62B246.96B279.83B231.43B291.03B
Net Income408.85B343.12B121.62B133.91B125.46B148.14B
Balance Sheet
Total Assets3.79T3.74T3.36T3.10T2.82T2.63T
Cash, Cash Equivalents and Short-Term Investments436.65B458.08B529.40B489.12B430.76B401.77B
Total Debt211.51B189.38B214.19B194.16B212.45B226.08B
Total Liabilities1.00T961.09B924.93B840.17B775.73B744.38B
Stockholders Equity2.72T2.73T2.39T2.23T2.01T1.85T
Cash Flow
Free Cash Flow340.80B225.28B168.56B104.06B115.71B134.96B
Operating Cash Flow434.32B354.64B283.23B211.85B228.86B232.84B
Investing Cash Flow-237.53B-265.79B-190.54B-81.58B-95.29B-99.86B
Financing Cash Flow-248.59B-189.37B-60.26B-95.47B-95.84B-104.93B

Otsuka Holdings Co Technical Analysis

Technical Analysis Sentiment
Positive
Last Price27.33
Price Trends
50DMA
27.40
Negative
100DMA
26.04
Positive
200DMA
25.48
Positive
Market Momentum
MACD
0.08
Negative
RSI
51.01
Neutral
STOCH
60.01
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OTSKY, the sentiment is Positive. The current price of 27.33 is above the 20-day moving average (MA) of 27.09, below the 50-day MA of 27.40, and above the 200-day MA of 25.48, indicating a neutral trend. The MACD of 0.08 indicates Negative momentum. The RSI at 51.01 is Neutral, neither overbought nor oversold. The STOCH value of 60.01 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for OTSKY.

Otsuka Holdings Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
$152.10B19.0040.62%2.62%2.71%6407.19%
77
Outperform
$94.05B13.2535.62%3.59%5.97%128.66%
76
Outperform
$120.76B12.318.39%4.45%-9.32%120.62%
74
Outperform
$29.63B9.9415.51%1.19%7.51%203.70%
74
Outperform
$22.51B14.299.31%5.00%-1.03%
69
Neutral
$94.93B15.7533.84%5.31%1.26%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OTSKY
Otsuka Holdings Co
27.33
-3.36
-10.95%
BIIB
Biogen
155.51
-16.52
-9.60%
BMY
Bristol-Myers Squibb
46.69
-10.30
-18.07%
GILD
Gilead Sciences
118.84
24.62
26.13%
GSK
GlaxoSmithKline
46.63
11.84
34.03%
SNY
Sanofi
49.66
0.60
1.22%

Otsuka Holdings Co Corporate Events

Otsuka Holdings Reports Strong Nine-Month Financial Results
Oct 31, 2025

Otsuka Holdings Co., Ltd. is a diversified healthcare company listed on the Tokyo Stock Exchange, operating primarily in the pharmaceuticals and nutraceuticals sectors, with a focus on innovative products that promote well-being. The company reported a solid financial performance for the nine-month period ending September 30, 2025, with revenue reaching ¥1,818,743 million, marking a 5.1% increase from the previous year. This growth was driven by strong sales in its pharmaceutical segment, particularly from its antipsychotic and anti-cancer agents, and a steady performance in its nutraceuticals business. Key financial highlights include a significant rise in operating profit by 56.1% to ¥407,421 million and a 55.3% increase in profit attributable to owners of the company, amounting to ¥297,658 million. The company’s strategic focus on expanding its product pipeline and enhancing its market presence was evident with increased research and development expenses and the acquisition of new subsidiaries. Looking ahead, Otsuka Holdings anticipates continued growth, supported by strong product demand and strategic investments, while navigating potential challenges such as pricing policies and tariffs in the U.S.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 01, 2025