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NovoCure Ltd (NVCR)
NASDAQ:NVCR
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NovoCure (NVCR) AI Stock Analysis

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NVCR

NovoCure

(NASDAQ:NVCR)

Rating:46Neutral
Price Target:
$11.00
▼(-7.64% Downside)
NovoCure's overall stock score is primarily influenced by its financial performance challenges, including persistent losses and high leverage. Technical analysis indicates a bearish trend, and valuation metrics are poor due to negative earnings. The earnings call provided some positive insights into clinical trials and market expansion, slightly offsetting the negative aspects.
Positive Factors
Earnings
2Q25 revenues beat consensus estimates, primarily driven by active patient growth across major markets.
Market Expansion
The company is engaging with Japanese regulators for the next pancreatic cancer PMA submission, indicating expansion into new markets.
Regulatory Progress
There is a high likelihood of FDA approval for the PANOVA-3 Phase 3 trial, which could positively impact the company's product pipeline.
Negative Factors
Mixed Launch Results
The disclosed metrics on the early lung cancer launch were mixed.
Prescription Trends
The number of unique prescribers decreased to 75 in 2Q from 93 in 1Q25, indicating a reduction in the number of doctors prescribing the treatment.

NovoCure (NVCR) vs. SPDR S&P 500 ETF (SPY)

NovoCure Business Overview & Revenue Model

Company DescriptionNovoCure Limited, an oncology company, engages in the development, manufacture, and commercialization of tumor treating fields (TTFields) devices for the treatment of solid tumor cancers in the United States, Europe, the Middle East, Africa, Japan, and Greater China. Its TTFields devices include Optune for the treatment of glioblastoma; and Optune Lua for the treatment of malignant pleural mesothelioma. The company also has ongoing or completed clinical trials investigating TTFields in brain metastases, gastric cancer, glioblastoma, liver cancer, non-small cell lung cancer, pancreatic cancer, and ovarian cancer. NovoCure Limited was incorporated in 2000 and is headquartered in Saint Helier, Jersey.
How the Company Makes MoneyNovoCure generates revenue primarily through the sales of its medical device, Optune, which is prescribed to patients for the treatment of certain types of cancer. The company earns money from both direct sales to hospitals and outpatient clinics, as well as through reimbursement from insurance providers and government healthcare programs. Key revenue streams include patient subscriptions and device rentals. NovoCure has established partnerships with healthcare providers and institutions for clinical trials and research collaborations that may enhance its market presence and facilitate broader adoption of its technology, contributing to future earnings growth.

NovoCure Earnings Call Summary

Earnings Call Date:Jul 24, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Oct 23, 2025
Earnings Call Sentiment Neutral
The earnings call presented a generally positive outlook with significant progress in clinical trials and market expansion. However, there are areas of concern such as the decreased growth in non-small cell lung cancer prescriptions, reduced gross margin, and a net loss for the quarter.
Q2-2025 Updates
Positive Updates
PANOVA-3 Trial Success in Pancreatic Cancer
The PANOVA-3 trial demonstrated a median overall survival of 16.2 months for patients using TTFields therapy combined with gemcitabine and nab-paclitaxel, which is 2 months greater than the control arm. This trial also showed significant improvements in pain-free survival.
METIS Trial Positive Results
The METIS trial met its primary endpoint with a statistically significant improvement in time to intracranial progression for patients treated with TTFields therapy. The trial showed a 28% risk reduction with a median time to progression of 15 months compared to 7.5 months for the control group.
Expansion of Optune Lua in Non-Small Cell Lung Cancer
Received 121 prescriptions for Optune Lua in the second quarter with $2.4 million in net revenues. The product is now being used widely with immune checkpoint inhibitors and docetaxel.
11th Consecutive Quarter of Active Patient Growth
The company saw a 7% increase in active patients, with all international markets experiencing double-digit growth.
Negative Updates
Lower Growth in Non-Small Cell Lung Cancer Prescriptions
Quarter-over-quarter growth in prescriptions for non-small cell lung cancer was less in Q2 compared to Q1, with only a 14 sequential increase in the U.S.
Reduced Gross Margin
The gross margin decreased to 74% from 77% due to the rollout of the HFE array and the ongoing launch of non-small cell lung cancer without established reimbursement.
Net Loss for the Quarter
Reported a net loss of $40 million with a loss per share of $0.36. Adjusted EBITDA was negative $10 million.
Company Guidance
During Novocure's second quarter 2025 earnings call, the company provided detailed guidance on several key metrics, showcasing a robust growth trajectory. The company reported net revenues of $159 million, marking a 6% increase from the same quarter last year, driven by 7% year-over-year growth in active patients within their GBM franchise. Novocure highlighted significant milestones, including the receipt of 121 prescriptions for Optune Lua in non-small cell lung cancer, contributing to $2.4 million in net revenues for this indication. The company also reported promising clinical data, such as the PANOVA-3 trial results in pancreatic cancer, where the TTFields therapy, combined with gemcitabine and nab-paclitaxel, demonstrated a median overall survival of 16.2 months for patients, 2 months longer than the control group. In brain metastases from non-small cell lung cancer, the METIS trial showed a 28% risk reduction in intracranial progression. Novocure is actively pursuing regulatory approvals, with expectations to file PMA submissions for pancreatic cancer and brain metastases in the third quarter. The company remains focused on expanding its indications and is preparing for potential launches in 2026, supported by a strong financial position, including a cash and investment balance of $912 million.

NovoCure Financial Statement Overview

Summary
NovoCure faces profitability challenges despite modest revenue growth, with high operational costs eroding profits. The balance sheet is stable with a solid equity base, but cash flow issues are concerning.
Income Statement
45
Neutral
NovoCure has shown a modest increase in revenue over the TTM period, with a revenue growth rate of 2.72%. However, the company is struggling with profitability, as indicated by negative net profit and EBIT margins of -26.41% and -26.84% respectively. The gross profit margin is relatively healthy at 77.16%, suggesting strong core operations but high operational costs are eroding profitability.
Balance Sheet
50
Neutral
The balance sheet presents a mixed picture. NovoCure has a relatively high debt-to-equity ratio of 0.25, indicating moderate leverage. The return on equity is negative due to the net loss, but the equity ratio is a healthy 59.98%, indicating a stable capital structure with sufficient equity backing.
Cash Flow
40
Negative
Cash flow is a concern for NovoCure, with negative free cash flow of -$72.14 million and deterioration in free cash flow growth. The operating cash flow to net income ratio is negative, reflecting challenges in converting profits into cash. The company appears to be burning cash, which poses a risk if not addressed.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue605.22M509.34M537.84M535.03M494.37M
Gross Profit468.04M381.06M422.97M420.15M387.87M
EBITDA-108.26M-175.87M-63.11M-38.38M45.30M
Net Income-168.63M-207.04M-92.53M-58.35M19.81M
Balance Sheet
Total Assets1.24B1.15B1.19B1.14B1.05B
Cash, Cash Equivalents and Short-Term Investments962.20M910.62M969.42M937.70M842.58M
Total Debt683.35M596.24M584.27M575.21M444.20M
Total Liabilities880.61M783.63M750.48M729.00M575.46M
Stockholders Equity360.18M362.50M441.17M410.49M476.53M
Cash Flow
Free Cash Flow-69.22M-100.43M9.43M58.59M84.18M
Operating Cash Flow-26.37M-73.34M30.79M82.76M99.15M
Investing Cash Flow-140.24M184.15M-139.96M-144.83M-472.85M
Financing Cash Flow90.31M15.79M15.49M25.70M440.21M

NovoCure Technical Analysis

Technical Analysis Sentiment
Negative
Last Price11.91
Price Trends
50DMA
14.41
Negative
100DMA
15.94
Negative
200DMA
19.64
Negative
Market Momentum
MACD
-0.62
Negative
RSI
42.42
Neutral
STOCH
47.71
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NVCR, the sentiment is Negative. The current price of 11.91 is above the 20-day moving average (MA) of 11.65, below the 50-day MA of 14.41, and below the 200-day MA of 19.64, indicating a neutral trend. The MACD of -0.62 indicates Negative momentum. The RSI at 42.42 is Neutral, neither overbought nor oversold. The STOCH value of 47.71 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for NVCR.

NovoCure Risk Analysis

NovoCure disclosed 41 risk factors in its most recent earnings report. NovoCure reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

NovoCure Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$1.88B-7.85%16.28%10.63%
60
Neutral
$1.23B-5.98%-18.61%92.36%
58
Neutral
$299.56M-25.78%34.29%-49.21%
56
Neutral
$1.36B55.81-25.55%-32.59%-667.81%
53
Neutral
$1.90B-14.80%-3.00%76.48%
51
Neutral
$7.83B-0.18-40.10%2.29%21.46%-2.03%
46
Neutral
$1.32B-48.07%14.58%0.86%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NVCR
NovoCure
11.91
-7.82
-39.64%
ATRC
Atricure
37.30
11.70
45.70%
QDEL
QuidelOrtho
27.77
-16.02
-36.58%
STAA
Staar Surgical
27.51
-4.40
-13.79%
BLFS
BioLife Solutions
25.43
0.08
0.32%
SMTI
Sanara MedTech
33.94
-0.21
-0.61%

NovoCure Corporate Events

Executive/Board ChangesShareholder Meetings
NovoCure Appoints New President at Annual Meeting
Neutral
Jun 6, 2025

On June 4, 2025, NovoCure held its annual general meeting where shareholders elected eleven directors to serve until the 2026 meeting, with no third-party arrangements involved. Additionally, Francis Leonard was appointed as President of NovoCure and awarded Restricted Share Units under the company’s incentive plan. The meeting also saw the approval of several proposals, including the ratification of the company’s independent auditor, a non-binding advisory vote on executive compensation, and the approval of the 2025 Employee Share Purchase Plan.

Product-Related AnnouncementsBusiness Operations and Strategy
NovoCure Announces Positive Phase 3 Trial Results
Positive
Jun 2, 2025

On May 31, 2025, Novocure announced positive results from its Phase 3 PANOVA-3 clinical trial at the ASCO Annual Meeting, demonstrating that TTFields therapy, when combined with gemcitabine and nab-paclitaxel, significantly improves overall survival and extends pain-free survival for patients with unresectable, locally advanced pancreatic adenocarcinoma. The findings, which will support a Premarket Approval submission to the FDA, highlight TTFields’ potential to become a standard treatment for this challenging cancer type, marking a significant advancement in Novocure’s market positioning and offering hope for improved patient outcomes.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2025