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NovoCure Ltd (NVCR)
NASDAQ:NVCR
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NovoCure (NVCR) AI Stock Analysis

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NVCR

NovoCure

(NASDAQ:NVCR)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
$12.50
▼(-1.42% Downside)
The overall stock score is primarily impacted by financial performance challenges, including persistent losses and high leverage. Technical analysis indicates a bearish trend, and valuation metrics are unattractive due to negative profitability. The positive outlook from the earnings call is not factored into the score due to its exclusion from the weighted calculation.
Positive Factors
Regulatory Approval in Japan
This approval expands NovoCure's market reach in Japan, enhancing its competitive position and potential revenue growth in the non-small cell lung cancer segment.
Clinical Trial Success
Successful trial results in pancreatic cancer demonstrate the efficacy of TTFields, potentially leading to expanded indications and increased adoption of NovoCure's technology.
Active Patient Growth
Consistent growth in active patients indicates strong demand for NovoCure's products, supporting long-term revenue growth and market expansion.
Negative Factors
High Leverage
High leverage could strain NovoCure's financial flexibility, increasing risk if profitability does not improve, potentially impacting long-term stability.
Negative Cash Flow
Inability to generate positive free cash flow may limit NovoCure's capacity to invest in growth opportunities and manage debt, affecting future financial health.
Persistent Net Losses
Ongoing net losses highlight profitability challenges, which could hinder NovoCure's ability to sustain operations and invest in R&D over the long term.

NovoCure (NVCR) vs. SPDR S&P 500 ETF (SPY)

NovoCure Business Overview & Revenue Model

Company DescriptionNovoCure Limited, an oncology company, engages in the development, manufacture, and commercialization of tumor treating fields (TTFields) devices for the treatment of solid tumor cancers in the United States, Europe, the Middle East, Africa, Japan, and Greater China. Its TTFields devices include Optune for the treatment of glioblastoma; and Optune Lua for the treatment of malignant pleural mesothelioma. The company also has ongoing or completed clinical trials investigating TTFields in brain metastases, gastric cancer, glioblastoma, liver cancer, non-small cell lung cancer, pancreatic cancer, and ovarian cancer. NovoCure Limited was incorporated in 2000 and is headquartered in Saint Helier, Jersey.
How the Company Makes MoneyNovoCure generates revenue primarily through the sales of its medical device, Optune, which is prescribed to patients for the treatment of certain types of cancer. The company earns money from both direct sales to hospitals and outpatient clinics, as well as through reimbursement from insurance providers and government healthcare programs. Key revenue streams include patient subscriptions and device rentals. NovoCure has established partnerships with healthcare providers and institutions for clinical trials and research collaborations that may enhance its market presence and facilitate broader adoption of its technology, contributing to future earnings growth.

NovoCure Earnings Call Summary

Earnings Call Date:Jul 24, 2025
(Q2-2025)
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% Change Since: |
Next Earnings Date:Oct 23, 2025
Earnings Call Sentiment Neutral
The earnings call presented a generally positive outlook with significant progress in clinical trials and market expansion. However, there are areas of concern such as the decreased growth in non-small cell lung cancer prescriptions, reduced gross margin, and a net loss for the quarter.
Q2-2025 Updates
Positive Updates
PANOVA-3 Trial Success in Pancreatic Cancer
The PANOVA-3 trial demonstrated a median overall survival of 16.2 months for patients using TTFields therapy combined with gemcitabine and nab-paclitaxel, which is 2 months greater than the control arm. This trial also showed significant improvements in pain-free survival.
METIS Trial Positive Results
The METIS trial met its primary endpoint with a statistically significant improvement in time to intracranial progression for patients treated with TTFields therapy. The trial showed a 28% risk reduction with a median time to progression of 15 months compared to 7.5 months for the control group.
Expansion of Optune Lua in Non-Small Cell Lung Cancer
Received 121 prescriptions for Optune Lua in the second quarter with $2.4 million in net revenues. The product is now being used widely with immune checkpoint inhibitors and docetaxel.
11th Consecutive Quarter of Active Patient Growth
The company saw a 7% increase in active patients, with all international markets experiencing double-digit growth.
Negative Updates
Lower Growth in Non-Small Cell Lung Cancer Prescriptions
Quarter-over-quarter growth in prescriptions for non-small cell lung cancer was less in Q2 compared to Q1, with only a 14 sequential increase in the U.S.
Reduced Gross Margin
The gross margin decreased to 74% from 77% due to the rollout of the HFE array and the ongoing launch of non-small cell lung cancer without established reimbursement.
Net Loss for the Quarter
Reported a net loss of $40 million with a loss per share of $0.36. Adjusted EBITDA was negative $10 million.
Company Guidance
During Novocure's second quarter 2025 earnings call, the company provided detailed guidance on several key metrics, showcasing a robust growth trajectory. The company reported net revenues of $159 million, marking a 6% increase from the same quarter last year, driven by 7% year-over-year growth in active patients within their GBM franchise. Novocure highlighted significant milestones, including the receipt of 121 prescriptions for Optune Lua in non-small cell lung cancer, contributing to $2.4 million in net revenues for this indication. The company also reported promising clinical data, such as the PANOVA-3 trial results in pancreatic cancer, where the TTFields therapy, combined with gemcitabine and nab-paclitaxel, demonstrated a median overall survival of 16.2 months for patients, 2 months longer than the control group. In brain metastases from non-small cell lung cancer, the METIS trial showed a 28% risk reduction in intracranial progression. Novocure is actively pursuing regulatory approvals, with expectations to file PMA submissions for pancreatic cancer and brain metastases in the third quarter. The company remains focused on expanding its indications and is preparing for potential launches in 2026, supported by a strong financial position, including a cash and investment balance of $912 million.

NovoCure Financial Statement Overview

Summary
NovoCure is experiencing revenue growth, but persistent losses and high leverage present significant challenges. The company needs to improve operational efficiencies and manage debt levels to enhance financial stability and profitability.
Income Statement
45
Neutral
NovoCure shows a steady increase in revenue over the years, with a 4.1% growth from 2024 to the TTM period. However, the company is struggling with profitability, as evidenced by persistent negative EBIT and net income margins. The gross profit margin remains healthy at around 76% for the TTM, but high operating expenses are impacting overall profitability.
Balance Sheet
50
Neutral
The company's balance sheet reflects a stable asset base with a consistent equity ratio around 28%. However, the debt-to-equity ratio of approximately 2.0 indicates a high level of leverage, which could pose risks if profitability does not improve. The return on equity remains negative due to continuous net losses.
Cash Flow
40
Negative
NovoCure's cash flow statement reveals challenges in generating positive free cash flow, with a negative free cash flow reported in the TTM. The operating cash flow to net income ratio is negative, indicating that the company is not generating sufficient cash from its operations to cover its net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue630.16M605.22M509.34M537.84M535.03M494.37M
Gross Profit481.33M468.04M381.06M422.97M420.15M387.87M
EBITDA-110.77M-108.26M-175.87M-63.11M-38.38M45.30M
Net Income-170.95M-168.63M-207.04M-92.53M-58.35M19.81M
Balance Sheet
Total Assets1.25B1.24B1.15B1.19B1.14B1.05B
Cash, Cash Equivalents and Short-Term Investments911.52M962.20M910.62M969.42M937.70M842.58M
Total Debt700.25M683.35M596.24M584.27M575.21M444.20M
Total Liabilities896.43M880.61M783.63M750.48M729.00M575.46M
Stockholders Equity349.44M360.18M362.50M441.17M410.49M476.53M
Cash Flow
Free Cash Flow-80.40M-69.22M-100.43M9.43M58.59M84.18M
Operating Cash Flow-44.68M-26.37M-73.34M30.79M82.76M99.15M
Investing Cash Flow17.50M-140.24M184.15M-139.96M-144.83M-472.85M
Financing Cash Flow10.42M90.31M15.79M15.49M25.70M440.21M

NovoCure Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price12.68
Price Trends
50DMA
13.12
Negative
100DMA
15.42
Negative
200DMA
19.32
Negative
Market Momentum
MACD
-0.05
Negative
RSI
52.57
Neutral
STOCH
41.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NVCR, the sentiment is Neutral. The current price of 12.68 is above the 20-day moving average (MA) of 12.21, below the 50-day MA of 13.12, and below the 200-day MA of 19.32, indicating a neutral trend. The MACD of -0.05 indicates Negative momentum. The RSI at 52.57 is Neutral, neither overbought nor oversold. The STOCH value of 41.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for NVCR.

NovoCure Risk Analysis

NovoCure disclosed 41 risk factors in its most recent earnings report. NovoCure reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

NovoCure Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
65.14B14.0920.41%2.16%-5.55%-4.81%
61
Neutral
1.72B-45.03-7.83%16.28%10.63%
61
Neutral
311.67M-30.15-28.07%34.29%-49.21%
60
Neutral
1.24B-217.91-1.59%-18.61%92.36%
58
Neutral
1.96B-4.42-16.70%-3.00%76.48%
45
Neutral
$1.42B-48.07%14.58%0.86%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NVCR
NovoCure
12.68
-4.93
-28.00%
ATRC
Atricure
35.96
7.97
28.47%
IMO
Imperial Oil
95.16
29.98
46.00%
QDEL
QuidelOrtho
29.53
-16.70
-36.12%
BLFS
BioLife Solutions
25.98
2.26
9.53%
SMTI
Sanara MedTech
35.08
3.97
12.76%

NovoCure Corporate Events

Business Operations and StrategyProduct-Related Announcements
NovoCure Gains Approval for Optune Lua in Japan
Positive
Sep 15, 2025

On September 15, 2025, Novocure announced that Japan’s Ministry of Health, Labour and Welfare approved Optune Lua® for use with PD-1/PD-L1 inhibitors in treating unresectable advanced/recurrent non-small cell lung cancer (NSCLC) after platinum-based chemotherapy. This approval, supported by the Phase 3 LUNAR trial, marks a significant advancement for patients, showing improved survival rates without severe side effects. The approval enhances Novocure’s market positioning in Japan, addressing the urgent need for innovative NSCLC treatments, and potentially benefiting stakeholders by providing a new therapeutic option.

The most recent analyst rating on (NVCR) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on NovoCure stock, see the NVCR Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 16, 2025