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BioLife Solutions (BLFS)
NASDAQ:BLFS
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BioLife Solutions (BLFS) AI Stock Analysis

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BLFS

BioLife Solutions

(NASDAQ:BLFS)

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Neutral 54 (OpenAI - 4o)
Rating:54Neutral
Price Target:
$26.00
▼(-1.89% Downside)
BioLife Solutions' overall stock score is driven by a mix of financial challenges and positive earnings call insights. The company's financial performance is hindered by declining revenues and profitability, but it benefits from a strong gross profit margin and conservative leverage. Technical analysis indicates mixed signals, with short-term bearish momentum but longer-term support. Valuation is a weak point due to significant losses and no dividend yield. However, the positive sentiment from the earnings call, highlighting strong revenue growth and strategic focus, provides a counterbalance, resulting in a moderate overall score.
Positive Factors
Revenue Growth
The significant growth in cell processing revenue indicates strong demand for BioLife's products, suggesting robust market positioning and potential for sustained revenue expansion.
Market Leadership
BioLife's high market share in approved therapies and clinical trials underscores its competitive advantage and leadership in the biopreservation sector, supporting long-term business stability.
Improved Profitability
The improvement in EBITDA margin reflects enhanced operational efficiency, indicating a scalable business model that can drive future profitability.
Negative Factors
Declining Revenue
The decline in revenue growth poses a challenge to financial health, potentially impacting long-term sustainability if not addressed.
Increased Operating Expenses
Rising operating expenses could pressure margins and profitability, necessitating cost management to maintain financial stability.
Adjusted Gross Margin Decline
The decline in gross margin may indicate challenges in maintaining cost efficiency, potentially affecting long-term profitability.

BioLife Solutions (BLFS) vs. SPDR S&P 500 ETF (SPY)

BioLife Solutions Business Overview & Revenue Model

Company DescriptionBioLife Solutions, Inc. develops, manufactures, and supplies bioproduction tools and services for the cell and gene therapy industry in the United States, Canada, Europe, the Middle East, Africa, and internationally. The company's products are used in the basic and applied research, and commercial manufacturing of biologic-based therapies. It offers proprietary biopreservation media products, including HypoThermosol FRS and CryoStor that are formulated to mitigate preservation-induced, delayed-onset cell damage and death; and the ThawSTAR line that includes automated vial and cryobag thawing products that control the heat and timing of the thawing process of biologic materials. The company also provides evo shipping containers that are cloud-connected passive storage and transport containers for temperature-sensitive biologics and pharmaceuticals; liquid nitrogen laboratory freezers, cryogenic equipment, and accessories; and biological and pharmaceutical storage services. It markets and sells its products directly, as well as through third party distributors. BioLife Solutions, Inc. was incorporated in 1987 and is headquartered in Bothell, Washington.
How the Company Makes MoneyBioLife Solutions generates revenue primarily through the sale of its biopreservation products and services to a diverse range of customers, including pharmaceutical companies, research institutions, and clinical laboratories involved in cell and gene therapy. Key revenue streams include direct sales of its proprietary media and cryopreservation solutions, as well as recurring revenue from long-term contracts with customers for product supply. The company also benefits from strategic partnerships with biotech firms and research organizations that enhance its market reach and product development capabilities. Additionally, BioLife Solutions may see increased earnings through collaborations that expand its product offerings and enter new markets, capitalizing on the growing demand for biopreservation solutions in the rapidly evolving life sciences sector.

BioLife Solutions Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Positive
BioLife Solutions demonstrated solid revenue growth and improved profitability, with strategic moves like the sale of the evo Cold Chain product line strengthening their financial position. However, challenges such as a decline in adjusted gross margin and increased operating expenses were noted. The overall sentiment is positive due to the strong growth metrics and strategic focus on core competencies.
Q3-2025 Updates
Positive Updates
Strong Revenue Growth
Cell processing revenue increased 33% year-over-year, contributing to a 31% increase in total revenue for the quarter. This growth reflects sustained strength across the biopreservation media franchise and broader cell processing portfolio.
Improved Profitability
Adjusted EBITDA margin expanded 500 basis points year-over-year to 28%, demonstrating the operating leverage inherent in the business model.
Sale of evo Cold Chain Product Line
The sale of the evo Cold Chain logistics product line for approximately $25 million in cash further strengthens the balance sheet, bringing cash and marketable securities to approximately $125 million.
Increased Guidance
Full year cell processing revenue guidance raised from $91 million-$93 million to $93 million-$94 million, representing a 26% to 28% year-over-year growth rate.
Market Leadership
BioLife's BPM products are embedded in 16 approved therapies and utilized in more than 250 commercially sponsored CGT clinical trials in the U.S., representing over a 70% share. Notably, this includes more than 30 Phase III trials where their share is nearly 80%.
Negative Updates
Adjusted Gross Margin Decline
Adjusted gross margin for Q3 was 64% compared with 67% in the prior year, primarily due to a $600,000 onetime inventory reserve and less favorable product mix.
Increased Operating Expenses
GAAP operating expenses for Q3 2025 were $28.2 million versus $21.8 million in Q3 2024, attributed to increases in cost of sales and an increase in stock-based compensation expense.
GAAP Operating Loss
GAAP operating loss for Q3 2025 was $89,000 versus $418,000 in the prior year, despite increased revenue.
Company Guidance
In the recent BioLife Solutions Third Quarter 2025 Conference Call, the company announced a strong financial performance with a 31% increase in total revenue, driven by a 33% rise in cell processing revenue. This growth was primarily attributed to the biopreservation media franchise and cell processing portfolio. The adjusted EBITDA margin improved by 500 basis points year-over-year to 28%, highlighting enhanced profitability. The sale of the evo Cold Chain product line for $25 million was noted, boosting cash and marketable securities to approximately $125 million. This strategic move allows BioLife to focus on its core cell processing competencies. The company raised its full-year 2025 revenue guidance, expecting total revenue to reach $95 million to $96 million, a 27% to 29% growth rate, and cell processing revenue to hit $93 million to $94 million, a 26% to 28% increase. The guidance reflects adjustments for the sale of evo and indicates strong momentum and sustainable growth prospects.

BioLife Solutions Financial Statement Overview

Summary
BioLife Solutions faces challenges with declining revenues and profitability, as evidenced by negative net profit margins and ROE. Despite these issues, the company maintains a strong gross profit margin and a conservative leverage position. Cash flow generation is moderate, but the decline in free cash flow growth is a concern. Overall, the company needs to address its profitability and revenue growth to improve its financial health.
Income Statement
45
Neutral
BioLife Solutions has experienced declining revenue over the TTM period, with a negative revenue growth rate of -3.27%. The company shows a strong gross profit margin of 81.42%, indicating efficient cost management. However, the net profit margin is negative at -7.23%, reflecting ongoing losses. The EBIT and EBITDA margins are also negative, suggesting operational challenges.
Balance Sheet
55
Neutral
The balance sheet shows a low debt-to-equity ratio of 0.069, indicating conservative leverage. However, the return on equity is negative at -1.61%, highlighting profitability issues. The equity ratio is relatively stable, suggesting a solid capital structure despite the negative ROE.
Cash Flow
50
Neutral
The cash flow statement reveals a decline in free cash flow growth of -7.74% over the TTM period. The operating cash flow to net income ratio is 0.55, indicating moderate cash generation relative to net income. The free cash flow to net income ratio is 0.74, showing some ability to convert earnings into cash.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue74.00M82.25M143.27M76.24M119.16M48.09M
Gross Profit59.27M53.67M46.75M53.82M37.75M27.44M
EBITDA-4.87M1.53M-45.24M-124.18M-16.65M1.48M
Net Income-3.21M-20.18M-66.43M-139.81M-8.91M2.67M
Balance Sheet
Total Assets392.08M399.49M412.71M450.23M552.60M234.83M
Cash, Cash Equivalents and Short-Term Investments78.95M104.58M44.18M62.70M69.87M90.46M
Total Debt20.68M30.17M33.83M43.71M26.88M11.15M
Total Liabilities38.34M50.58M75.05M86.04M71.85M29.58M
Stockholders Equity353.74M348.91M337.66M364.19M480.75M205.25M
Cash Flow
Free Cash Flow10.56M5.20M-18.88M-18.87M-13.22M1.88M
Operating Cash Flow16.84M8.43M-12.50M-8.49M-4.84M6.51M
Investing Cash Flow961.00K58.30M17.84M-58.12M-12.64M-23.73M
Financing Cash Flow-4.09M-6.78M10.59M16.32M-2.78M102.08M

BioLife Solutions Technical Analysis

Technical Analysis Sentiment
Positive
Last Price26.50
Price Trends
50DMA
26.44
Positive
100DMA
25.08
Positive
200DMA
24.32
Positive
Market Momentum
MACD
-0.16
Negative
RSI
52.47
Neutral
STOCH
87.62
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BLFS, the sentiment is Positive. The current price of 26.5 is above the 20-day moving average (MA) of 26.03, above the 50-day MA of 26.44, and above the 200-day MA of 24.32, indicating a bullish trend. The MACD of -0.16 indicates Negative momentum. The RSI at 52.47 is Neutral, neither overbought nor oversold. The STOCH value of 87.62 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BLFS.

BioLife Solutions Risk Analysis

BioLife Solutions disclosed 34 risk factors in its most recent earnings report. BioLife Solutions reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioLife Solutions Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$1.39B-10.6983.78%-25.37%
56
Neutral
$1.38B-12.401.37%-9.49%56.22%
54
Neutral
$1.28B-5.20%-18.82%92.56%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.32B-24.65%-32.42%-540.37%
44
Neutral
$927.74M-12.06-86.99%-40.63%
41
Neutral
$186.93M-27.19%30.55%-340.19%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BLFS
BioLife Solutions
26.50
-0.77
-2.82%
AZTA
Azenta
35.56
-11.65
-24.68%
STAA
Staar Surgical
26.54
-1.18
-4.26%
PLSE
Pulse Biosciences
13.69
-7.19
-34.43%
SMTI
Sanara MedTech
20.92
-15.27
-42.19%
KMTS
Kestra Medical Technologies Ltd.
26.98
5.99
28.54%

BioLife Solutions Corporate Events

BioLife Solutions Reports Strong Q3 Earnings Growth
Nov 8, 2025

BioLife Solutions Inc has reported a positive sentiment in its latest earnings call, showcasing strong revenue growth and improved profitability. The company has made strategic moves, such as the sale of the evo Cold Chain product line, to bolster its financial position. Despite some challenges, including a decline in adjusted gross margin and increased operating expenses, the overall outlook remains optimistic due to robust growth metrics and a strategic focus on core competencies.

BioLife Solutions Reports Strong Q3 2025 Growth
Nov 7, 2025

BioLife Solutions Inc., a prominent player in the cell and gene therapy market, specializes in developing and supplying cell processing tools and services that ensure the viability of biologic materials throughout their lifecycle.

Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
BioLife Solutions Holds Annual Stockholders Meeting
Neutral
Aug 21, 2025

On August 20, 2025, BioLife Solutions, Inc. conducted its annual meeting of stockholders, where key decisions were made. The stockholders re-elected seven directors, approved executive compensation on a non-binding basis, and ratified the appointment of Grant Thornton LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025. These decisions reflect the company’s ongoing governance and operational strategies, potentially impacting its market positioning and stakeholder confidence.

The most recent analyst rating on (BLFS) stock is a Hold with a $27.00 price target. To see the full list of analyst forecasts on BioLife Solutions stock, see the BLFS Stock Forecast page.

BioLife Solutions Reports Strong Q2 Growth Amid Challenges
Aug 13, 2025

BioLife Solutions Inc. recently held its Q2 2025 earnings call, showcasing a mixed sentiment among stakeholders. The company reported significant revenue growth and increased guidance, reflecting strong operational performance and future potential. However, the overall financial results were tempered by increased operating expenses and net loss, primarily due to noncash charges. Despite these challenges, BioLife’s robust cash position and strategic investments suggest a promising outlook for future growth.

BioLife Solutions Reports Strong Q2 2025 Growth
Aug 8, 2025

BioLife Solutions Inc., a prominent player in the cell and gene therapy market, specializes in developing and supplying cell processing tools and services. The company is recognized for its biopreservation media and other innovative solutions that support the commercialization of new therapies.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025