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BioLife Solutions Inc (BLFS)
:BLFS

BioLife Solutions (BLFS) AI Stock Analysis

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BLFS

BioLife Solutions

(NASDAQ:BLFS)

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Neutral 52 (OpenAI - 4o)
Rating:52Neutral
Price Target:
$25.00
▼(-0.28% Downside)
BioLife Solutions' overall stock score reflects a mix of positive and negative factors. The most significant strength is the strong revenue growth and improved profitability highlighted in the recent earnings call, which suggests potential for future growth. However, financial performance challenges, including declining revenues and profitability, weigh heavily on the score. Technical indicators suggest a bearish trend, and valuation metrics indicate overvaluation. The absence of a dividend yield further impacts the valuation score.
Positive Factors
Revenue Growth
Strong revenue growth in cell processing indicates robust demand and market expansion, supporting long-term business sustainability.
Market Leadership
Dominant market position in cell and gene therapy trials enhances competitive advantage and potential for future growth.
Strategic Focus
Divesting non-core assets allows focus on core competencies, strengthening financial position and supporting strategic growth.
Negative Factors
Declining Gross Margin
Declining gross margins can pressure profitability, indicating potential challenges in cost management and pricing strategy.
Increased Operating Expenses
Rising operating expenses may strain profitability and cash flow, requiring efficiency improvements to sustain long-term growth.
Negative Profitability
Ongoing losses and negative profitability metrics highlight operational challenges, impacting financial health and investor confidence.

BioLife Solutions (BLFS) vs. SPDR S&P 500 ETF (SPY)

BioLife Solutions Business Overview & Revenue Model

Company DescriptionBioLife Solutions, Inc. develops, manufactures, and supplies bioproduction tools and services for the cell and gene therapy industry in the United States, Canada, Europe, the Middle East, Africa, and internationally. The company's products are used in the basic and applied research, and commercial manufacturing of biologic-based therapies. It offers proprietary biopreservation media products, including HypoThermosol FRS and CryoStor that are formulated to mitigate preservation-induced, delayed-onset cell damage and death; and the ThawSTAR line that includes automated vial and cryobag thawing products that control the heat and timing of the thawing process of biologic materials. The company also provides evo shipping containers that are cloud-connected passive storage and transport containers for temperature-sensitive biologics and pharmaceuticals; liquid nitrogen laboratory freezers, cryogenic equipment, and accessories; and biological and pharmaceutical storage services. It markets and sells its products directly, as well as through third party distributors. BioLife Solutions, Inc. was incorporated in 1987 and is headquartered in Bothell, Washington.
How the Company Makes MoneyBioLife Solutions generates revenue primarily through the sale of its biopreservation products, which include cryopreservation media, storage containers, and automated thawing systems. The company also earns income from its proprietary technology licenses and research collaborations with pharmaceutical and biotechnology companies. Key revenue streams include direct product sales, partnerships with major players in the cell and gene therapy sectors, and ongoing contracts with research institutions. Significant partnerships with industry leaders enhance BioLife's market presence and contribute to its earnings by expanding its customer base and driving product adoption in various therapeutic applications.

BioLife Solutions Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Positive
BioLife Solutions demonstrated solid revenue growth and improved profitability, with strategic moves like the sale of the evo Cold Chain product line strengthening their financial position. However, challenges such as a decline in adjusted gross margin and increased operating expenses were noted. The overall sentiment is positive due to the strong growth metrics and strategic focus on core competencies.
Q3-2025 Updates
Positive Updates
Strong Revenue Growth
Cell processing revenue increased 33% year-over-year, contributing to a 31% increase in total revenue for the quarter. This growth reflects sustained strength across the biopreservation media franchise and broader cell processing portfolio.
Improved Profitability
Adjusted EBITDA margin expanded 500 basis points year-over-year to 28%, demonstrating the operating leverage inherent in the business model.
Sale of evo Cold Chain Product Line
The sale of the evo Cold Chain logistics product line for approximately $25 million in cash further strengthens the balance sheet, bringing cash and marketable securities to approximately $125 million.
Increased Guidance
Full year cell processing revenue guidance raised from $91 million-$93 million to $93 million-$94 million, representing a 26% to 28% year-over-year growth rate.
Market Leadership
BioLife's BPM products are embedded in 16 approved therapies and utilized in more than 250 commercially sponsored CGT clinical trials in the U.S., representing over a 70% share. Notably, this includes more than 30 Phase III trials where their share is nearly 80%.
Negative Updates
Adjusted Gross Margin Decline
Adjusted gross margin for Q3 was 64% compared with 67% in the prior year, primarily due to a $600,000 onetime inventory reserve and less favorable product mix.
Increased Operating Expenses
GAAP operating expenses for Q3 2025 were $28.2 million versus $21.8 million in Q3 2024, attributed to increases in cost of sales and an increase in stock-based compensation expense.
GAAP Operating Loss
GAAP operating loss for Q3 2025 was $89,000 versus $418,000 in the prior year, despite increased revenue.
Company Guidance
In the recent BioLife Solutions Third Quarter 2025 Conference Call, the company announced a strong financial performance with a 31% increase in total revenue, driven by a 33% rise in cell processing revenue. This growth was primarily attributed to the biopreservation media franchise and cell processing portfolio. The adjusted EBITDA margin improved by 500 basis points year-over-year to 28%, highlighting enhanced profitability. The sale of the evo Cold Chain product line for $25 million was noted, boosting cash and marketable securities to approximately $125 million. This strategic move allows BioLife to focus on its core cell processing competencies. The company raised its full-year 2025 revenue guidance, expecting total revenue to reach $95 million to $96 million, a 27% to 29% growth rate, and cell processing revenue to hit $93 million to $94 million, a 26% to 28% increase. The guidance reflects adjustments for the sale of evo and indicates strong momentum and sustainable growth prospects.

BioLife Solutions Financial Statement Overview

Summary
BioLife Solutions faces challenges with declining revenues and profitability, as evidenced by negative net profit margins and ROE. Despite these issues, the company maintains a strong gross profit margin and a conservative leverage position. Cash flow generation is moderate, but the decline in free cash flow growth is a concern. Overall, the company needs to address its profitability and revenue growth to improve its financial health.
Income Statement
45
Neutral
BioLife Solutions has experienced declining revenue over the TTM period, with a negative revenue growth rate of -3.27%. The company shows a strong gross profit margin of 81.42%, indicating efficient cost management. However, the net profit margin is negative at -7.23%, reflecting ongoing losses. The EBIT and EBITDA margins are also negative, suggesting operational challenges.
Balance Sheet
55
Neutral
The balance sheet shows a low debt-to-equity ratio of 0.069, indicating conservative leverage. However, the return on equity is negative at -1.61%, highlighting profitability issues. The equity ratio is relatively stable, suggesting a solid capital structure despite the negative ROE.
Cash Flow
50
Neutral
The cash flow statement reveals a decline in free cash flow growth of -7.74% over the TTM period. The operating cash flow to net income ratio is 0.55, indicating moderate cash generation relative to net income. The free cash flow to net income ratio is 0.74, showing some ability to convert earnings into cash.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue74.00M82.25M143.27M76.24M119.16M48.09M
Gross Profit59.27M53.67M46.75M53.82M37.75M27.44M
EBITDA-4.87M1.53M-45.24M-124.18M-16.65M1.48M
Net Income-3.21M-20.18M-66.43M-139.81M-8.91M2.67M
Balance Sheet
Total Assets392.08M399.49M412.71M450.23M552.60M234.83M
Cash, Cash Equivalents and Short-Term Investments78.95M104.58M44.18M62.70M69.87M90.46M
Total Debt20.68M30.17M33.83M43.71M26.88M11.15M
Total Liabilities38.34M50.58M75.05M86.04M71.85M29.58M
Stockholders Equity353.74M348.91M337.66M364.19M480.75M205.25M
Cash Flow
Free Cash Flow10.56M5.20M-18.88M-18.87M-13.22M1.88M
Operating Cash Flow16.84M8.43M-12.50M-8.49M-4.84M6.51M
Investing Cash Flow961.00K58.30M17.84M-58.12M-12.64M-23.73M
Financing Cash Flow-4.09M-6.78M10.59M16.32M-2.78M102.08M

BioLife Solutions Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price25.07
Price Trends
50DMA
26.26
Negative
100DMA
25.57
Negative
200DMA
24.24
Positive
Market Momentum
MACD
-0.31
Negative
RSI
46.60
Neutral
STOCH
55.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BLFS, the sentiment is Neutral. The current price of 25.07 is below the 20-day moving average (MA) of 25.45, below the 50-day MA of 26.26, and above the 200-day MA of 24.24, indicating a neutral trend. The MACD of -0.31 indicates Negative momentum. The RSI at 46.60 is Neutral, neither overbought nor oversold. The STOCH value of 55.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for BLFS.

BioLife Solutions Risk Analysis

BioLife Solutions disclosed 34 risk factors in its most recent earnings report. BioLife Solutions reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioLife Solutions Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$1.58B-28.121.41%-9.49%58.97%
52
Neutral
$1.59B-10.18-136.96%62.06%-41.97%
52
Neutral
$1.21B-5.20%-18.82%92.56%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$1.25B-12.85-24.65%-32.42%-540.37%
44
Neutral
$1.03B-86.99%-40.63%
42
Neutral
$216.33M-5.57-27.19%30.55%-340.19%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BLFS
BioLife Solutions
25.07
-2.32
-8.47%
AZTA
Azenta
34.43
-16.00
-31.73%
STAA
Staar Surgical
25.14
0.32
1.29%
PLSE
Pulse Biosciences
15.26
-2.72
-15.13%
SMTI
Sanara MedTech
24.21
-9.47
-28.12%
KMTS
Kestra Medical Technologies Ltd.
27.32
6.33
30.16%

BioLife Solutions Corporate Events

M&A TransactionsBusiness Operations and StrategyFinancial Disclosures
BioLife Solutions Highlights Financial Performance in Presentation
Positive
Nov 17, 2025

On November 17, 2025, BioLife Solutions released an investor presentation highlighting its financial performance and strategic focus. The company reported a revenue guidance of $95-96 million for fiscal year 2025, with an expected organic revenue growth of 27-29%. BioLife Solutions has successfully refocused its portfolio by divesting non-core assets and targeting acquisitions, which has led to improved profitability and sustainable growth. The presentation also emphasized the company’s involvement in over 950 active global cell-based therapy trials, underscoring its strong market positioning and commitment to innovation in the cell-based therapy industry.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 09, 2025