Strong Revenue Growth
Total 2025 revenue grew 29% year-over-year to $96.2M; Q4 2025 revenue was $24.8M, up 20% year-over-year and landing at the high end of guidance.
Significant EBITDA and Profitability Improvement
Adjusted EBITDA for full-year 2025 increased to $25.0M (26% of revenue) from $13.3M (18% of revenue) in 2024. Q4 adjusted EBITDA was $6.9M (28% of revenue) versus $3.7M (18%) prior-year.
Turnaround to Positive Adjusted Operating and Net Income
Full-year adjusted operating income was $2.9M (vs. adjusted operating loss of $2.6M in 2024). Full-year adjusted net income was $6.3M (vs. adjusted net loss of $2.9M in 2024). Q4 adjusted net income was $1.9M (vs. adjusted net loss of $0.1M prior-year).
Healthy Liquidity and Balance Sheet Actions
Cash and marketable securities totaled $120.2M at 12/31/2025 (up from $105.4M at 12/31/2024). Cash increased in Q4 largely due to $23.5M cash proceeds from the divestiture of SAVSU; remaining SGD debt was $5.0M expected to be paid off by June 2026.
Clear 2026 Financial Guidance
2026 guidance calls for revenue of $112.5M–$115.0M (growth of 17%–20%), mid-60s gross margin, further adjusted EBITDA margin expansion, and expected full-year GAAP net income for the first time in many years.
Market Leadership in BPM and Commercial Traction
BPM accounted for ~85% of Q4 revenue; top 20 BPM customers ~80% of BPM revenue. BPM products embedded in 16 approved therapies and used in >250 relevant commercially sponsored CGT trials in the U.S. (representing >70% share), including >30 Phase 3 trials where share approaches ~80%.
Shift Toward Commercial Customers
Commercial BPM customers represented nearly 50% of revenue in 2025, up from the low-40s in 2024, improving visibility and supporting near- and long-term revenue predictability; management expects commercial mix to be ~50%–55% in 2026.
Operational and Strategic Initiatives
ERP manufacturing modules implemented with no disruption, enabling greater automation and controls. Strategic actions include acquisition of Panthera, investment in Pluristics, and a distribution/product development partnership with Qkine for cytokines and CellSeal vial integration.
Cross-Sell Opportunity
Management estimates that cross-selling additional cell processing tools to existing BPM customers could increase revenue per patient dose by 2x–3x over BPM alone; widespread adoption would be a multi-year opportunity and a strategic focus for 2026.