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Niagen Bioscience (NAGE)
NASDAQ:NAGE
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Niagen Bioscience (NAGE) AI Stock Analysis

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NAGE

Niagen Bioscience

(NASDAQ:NAGE)

Rating:73Outperform
Price Target:
$11.00
▲(12.70% Upside)
Niagen Bioscience's overall stock score reflects its strong financial performance and positive earnings call, which are the most significant factors. The company's strategic growth initiatives and improved profitability are promising. However, the high P/E ratio and mixed technical indicators suggest caution. Regulatory challenges and potential delays in study results also pose risks.
Positive Factors
Clinical Trials and Pharmaceutical Applications
Niagen's proprietary molecules are undergoing multiple clinical trials for various rare diseases and pharmaceutical applications that could further unlock additional value.
Product Innovation and Market Expansion
Niagen Bioscience continues to see growing consumer interest around boosting NAD+ levels to help with healthy aging and has been innovating ways to help consumers meet their needs.
Revenue and Earnings Performance
Niagen Bioscience's revenue and earnings have exceeded expectations, leading to an increased price target.
Negative Factors
Clinical Data and Legal Risks
Risks include slower-than-projected U.S. sales growth, unfavorable clinical data, and adverse legal decisions.
Sales Growth Risks
Risks to consider include slower-than-projected sales growth in the U.S. and potential adverse legal or geopolitical factors.

Niagen Bioscience (NAGE) vs. SPDR S&P 500 ETF (SPY)

Niagen Bioscience Business Overview & Revenue Model

Company DescriptionNiagen Bioscience (NAGE) is a biotechnology company focused on the research, development, and commercialization of innovative health and wellness products. The company operates primarily within the nutraceuticals sector, specializing in the production of nicotinamide riboside (NR), a precursor to NAD+ (nicotinamide adenine dinucleotide). NR is associated with various health benefits, including cellular energy production, anti-aging effects, and improved metabolic health. Niagen's core products include dietary supplements aimed at enhancing cellular health and longevity, catering to a growing consumer demand for wellness-oriented solutions.
How the Company Makes MoneyNiagen Bioscience generates revenue through the sale of its proprietary nicotinamide riboside products, which are marketed directly to consumers and through partnerships with various health and wellness retailers. The company employs a direct-to-consumer model via its online platform, leveraging e-commerce to reach a broad audience. Additionally, Niagen collaborates with third-party manufacturers and distributors to expand its market reach. Key revenue streams include retail sales, online sales, and potential licensing agreements for its patented NR technology. Ongoing research and development efforts aimed at discovering new applications for NR may also lead to future revenue opportunities through product diversification and partnerships with other biotech firms.

Niagen Bioscience Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q1-2025)
|
% Change Since: |
Next Earnings Date:Oct 29, 2025
Earnings Call Sentiment Positive
The earnings call for Niagen Bioscience presented a robust performance with significant revenue growth, increased net income, and cash generation. The expansion of Niagen Plus and a strengthened patent portfolio were key positive aspects. However, the company faces regulatory challenges and market misconceptions that require ongoing attention.
Q1-2025 Updates
Positive Updates
Strong Revenue Growth
In the first quarter of 2025, Niagen Bioscience achieved $30.5 million in revenue, marking a 38% year-over-year increase, with significant contributions from e-commerce and Niagen ingredient business.
Increased Net Income
The company reported a net income of $5.1 million, a substantial improvement from a net loss of $0.5 million in the first quarter of 2024.
Significant Cash Generation
Niagen Bioscience generated $7.9 million in cash from operations and ended the quarter with $55.6 million in cash and no debt.
Expansion of Niagen Plus
Niagen Plus, an intravenous and injection Niagen product, is now available at almost 600 clinics nationwide, with plans to expand to 1,000 clinics by the end of the year.
Patent Portfolio Expansion
A new composition of matter patent was granted, expanding protection for all salt forms of nicotinamide riboside.
Negative Updates
Regulatory Challenges with NMN
The FDA ruled that NMN is not a lawful dietary ingredient, creating potential market confusion and regulatory challenges.
Market Misconceptions
There continues to be a misconception that supplementing with NAD itself is effective, with many non-compliant products being marketed, necessitating market surveillance and consumer education efforts.
Company Guidance
During the first quarter of 2025, Niagen Biosciences achieved a remarkable 38% year-over-year revenue increase, reaching $30.5 million, and reported a net income of $5.1 million. The company generated $7.9 million in cash from operations, ending the quarter with $55.6 million in cash and no debt. E-commerce was a significant growth driver, with net sales of $16.8 million, marking a 31% increase year-over-year. The food grade and pharmaceutical grade Niagen ingredient business grew to $8 million, a substantial 95% increase compared to the previous year. Additionally, gross margin improved to 63.4%, up 270 basis points from the previous year's 60.7%. Looking ahead, the company raised its full-year top-line growth outlook to a range of 20% to 25%, reflecting continued confidence in the expanding NAD market and sustained business momentum.

Niagen Bioscience Financial Statement Overview

Summary
Niagen Bioscience has shown remarkable financial improvement, transitioning from losses to profitability. Revenue growth and margin improvements are notable, supported by a strong balance sheet with low leverage. Cash flow generation is robust, enhancing financial flexibility. The company is well-positioned for future growth, though maintaining these trends will be crucial.
Income Statement
85
Very Positive
Niagen Bioscience has shown impressive revenue growth, with a 19.17% increase from 2023 to 2024. The gross profit margin improved to 61.83% in 2024, indicating strong cost management. The company turned profitable in 2024 with a net profit margin of 8.59%, a significant improvement from previous losses. EBIT and EBITDA margins also turned positive, reflecting operational efficiency gains.
Balance Sheet
78
Positive
The balance sheet is robust, with a low debt-to-equity ratio of 0.06, indicating minimal leverage. The equity ratio stands at 67.52%, showcasing a strong equity base. Return on equity improved significantly to 18.55% in 2024, highlighting effective use of equity to generate profits.
Cash Flow
82
Very Positive
Cash flow performance is strong, with a 71.43% increase in free cash flow from 2023 to 2024. The operating cash flow to net income ratio is 1.42, indicating healthy cash generation relative to profits. The free cash flow to net income ratio is 1.40, demonstrating efficient cash conversion.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue116.30M99.60M83.57M72.05M67.45M59.26M
Gross Profit73.99M61.59M50.78M42.80M41.49M35.27M
EBITDA18.12M9.21M-3.89M-16.74M-25.45M-18.34M
Net Income17.73M8.55M-4.94M-16.54M-27.13M-19.93M
Balance Sheet
Total Assets91.53M68.28M54.96M54.06M57.84M38.36M
Cash, Cash Equivalents and Short-Term Investments60.32M44.51M27.17M20.29M28.02M16.50M
Total Debt3.29M2.65M3.28M4.26M4.70M1.64M
Total Liabilities27.33M22.18M26.51M25.39M26.11M21.93M
Stockholders Equity64.19M46.09M28.46M28.67M31.73M16.42M
Cash Flow
Free Cash Flow20.93M11.95M6.97M-15.43M-24.57M-10.74M
Operating Cash Flow21.21M12.11M7.12M-15.10M-24.16M-10.60M
Investing Cash Flow-257.00K-143.00K-143.00K-334.00K-409.00K-165.00K
Financing Cash Flow11.63M5.37M-90.00K7.65M36.09M8.65M

Niagen Bioscience Technical Analysis

Technical Analysis Sentiment
Negative
Last Price9.76
Price Trends
50DMA
10.96
Negative
100DMA
10.15
Negative
200DMA
8.29
Positive
Market Momentum
MACD
-0.17
Negative
RSI
45.34
Neutral
STOCH
53.09
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NAGE, the sentiment is Negative. The current price of 9.76 is above the 20-day moving average (MA) of 9.74, below the 50-day MA of 10.96, and above the 200-day MA of 8.29, indicating a neutral trend. The MACD of -0.17 indicates Negative momentum. The RSI at 45.34 is Neutral, neither overbought nor oversold. The STOCH value of 53.09 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for NAGE.

Niagen Bioscience Risk Analysis

Niagen Bioscience disclosed 58 risk factors in its most recent earnings report. Niagen Bioscience reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Niagen Bioscience Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
73
Outperform
$800.72M46.7637.36%35.89%
51
Neutral
$7.83B-0.18-40.10%2.29%21.46%-2.03%
50
Neutral
$460.27M-1.44%
45
Neutral
$484.09M-31.58%-51.13%7.57%
44
Neutral
$617.98M-55.41%-22.52%-37.00%
39
Underperform
$481.10M
-25.10%-7.06%
33
Underperform
$833.02M-109.12%7.58%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NAGE
Niagen Bioscience
9.76
6.40
190.48%
SVA
Sinovac Biotech
6.47
0.00
0.00%
BCYC
Bicycle Therapeutics
7.00
-14.66
-67.68%
OPT
Opthea Limited Sponsored ADR
3.20
0.17
5.61%
MRVI
Maravai Lifesciences Holdings
2.33
-6.88
-74.70%
SANA
Sana Biotechnology
3.37
-2.74
-44.84%

Niagen Bioscience Corporate Events

Business Operations and StrategyFinancial Disclosures
Niagen Bioscience Reports Strong Q2 Sales Growth
Positive
Aug 6, 2025

On August 6, 2025, Niagen Bioscience reported a 37% increase in net sales to $31.1 million for the second quarter of 2025, with a net income of $3.6 million. The company also raised its full-year revenue outlook, expecting growth between 22% and 27%, driven by strong sales of Tru Niagen® and Niagen® ingredients. Recent operational highlights include the completion of the Phase III NOPARK trial for Parkinson’s disease and a partnership with Haukeland University Hospital. The company also expanded its presence in luxury hospitality and wellness clinics, reflecting its strategic focus on growth and innovation in the NAD+ market.

Business Operations and Strategy
Niagen Bioscience Subsidiary Signs Supply Agreement
Neutral
Jul 29, 2025

On July 25, 2025, ChromaDex, Inc., a subsidiary of Niagen Bioscience, signed a Supply Agreement with W. R. Grace & Co.-Conn, effective April 1, 2025, for the exclusive supply of Nicotinamide-beta-Riboside Chloride (NRCL). The agreement, which runs until April 30, 2029, includes provisions for automatic renewal and requires ChromaDex to purchase a minimum quantity of NRCL annually. The agreement also outlines a potential future License Agreement for ChromaDex to manufacture NRCL, though its execution is not guaranteed.

Shareholder MeetingsBusiness Operations and Strategy
Niagen Bioscience Approves Equity Plan Amendment
Positive
Jun 27, 2025

At the Annual Meeting of Stockholders on June 24, 2025, Niagen Bioscience‘s shareholders approved an amendment to the 2017 Equity Incentive Plan, increasing the available shares by 4.75 million. Additionally, the Employee Stock Purchase Plan was approved, allowing employees to purchase shares at a discounted rate. These decisions are expected to enhance employee engagement and align stakeholder interests with the company’s growth objectives.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 28, 2025