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Vir Biotechnology, Inc. (VIR)
NASDAQ:VIR
US Market

Vir Biotechnology (VIR) AI Stock Analysis

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VIR

Vir Biotechnology

(NASDAQ:VIR)

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Neutral 48 (OpenAI - 4o)
Rating:48Neutral
Price Target:
$6.00
▲(0.67% Upside)
Vir Biotechnology's overall stock score is primarily impacted by its financial performance challenges, including declining revenues and profitability issues. While the technical analysis and recent corporate events provide some positive signals, the negative valuation metrics and ongoing financial losses weigh heavily on the score.
Positive Factors
Strategic Partnerships
The partnership with Norgine provides significant financial milestones and shared development costs, enhancing Vir's market position and financial stability.
Strong Cash Position
A strong cash position ensures operational flexibility and supports ongoing R&D efforts, crucial for long-term growth and stability.
Clinical Progress
Advancing clinical trials positions Vir for potential regulatory approvals, boosting future revenue streams and market competitiveness.
Negative Factors
Declining Revenue
Declining revenues indicate challenges in product sales and market penetration, which could hinder long-term financial performance and growth.
High R&D Expenses
High R&D costs strain financial resources and require successful outcomes to justify investments, impacting profitability if not managed well.
Continued Financial Losses
Ongoing financial losses highlight operational inefficiencies and the need for improved cost management to achieve sustainable profitability.

Vir Biotechnology (VIR) vs. SPDR S&P 500 ETF (SPY)

Vir Biotechnology Business Overview & Revenue Model

Company DescriptionVir Biotechnology, Inc., a commercial-stage immunology company, develops therapeutic products to treat and prevent serious infectious diseases. It develops Sotrovimab (VIR-7832), a SARS-CoV-2-neutralizing mAbs to treat and prevent COVID-19 infection under the Xevudy brand; VIR-2218 and VIR-3434 for the treatment of hepatitis B virus; VIR-2482 for the prevention of influenza A virus; and VIR-1111 for the prevention of human immunodeficiency virus. The company has grant agreements with Bill & Melinda Gates Foundation and National Institutes of Health; an option and license agreement with Brii Biosciences Limited and Brii Biosciences Offshore Limited; a collaboration and license agreement with Alnylam Pharmaceuticals, Inc.; license agreements with The Rockefeller University and MedImmune, Inc.; collaboration with WuXi Biologics and Glaxo Wellcome UK Ltd.; and a collaborative research agreement with GlaxoSmithKline Biologicals SA. It also has a manufacturing agreement with Samsung Biologics Co.,Ltd. for the manufacture of SARS-COV-2 antibodies; and clinical collaboration with Gilead Sciences, Inc. for chronic hepatitis B virus. Vir Biotechnology, Inc. was incorporated in 2016 and is headquartered in San Francisco, California.
How the Company Makes MoneyVir Biotechnology generates revenue primarily through the development and commercialization of its therapeutic products. Key revenue streams include sales of approved products, licensing agreements, and collaborations with pharmaceutical companies. The company has entered into significant partnerships, such as its collaboration with GlaxoSmithKline for the development of COVID-19 treatments, which can lead to milestone payments and royalties on future sales. Additionally, Vir may receive funding from government grants and contracts, especially during public health emergencies, contributing to its financial earnings.

Vir Biotechnology Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Provides insight into which business areas are driving sales, highlighting strengths and potential vulnerabilities in the company's revenue streams.
Chart InsightsVir Biotechnology's revenue from collaborations has experienced volatility, with recent quarters showing negative or minimal contributions. Despite this, the company is advancing its hepatitis delta and oncology programs, as highlighted in the latest earnings call. The focus on these strategic initiatives, alongside cost efficiency improvements, suggests a potential shift towards stabilizing revenues through new partnerships and commercialization efforts. However, the continued net losses and cash consumption underscore the financial challenges ahead, making the success of these programs crucial for future revenue growth.
Data provided by:The Fly

Vir Biotechnology Earnings Call Summary

Earnings Call Date:Nov 05, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in key clinical programs and a strong financial position, with clear paths to future value creation. However, continuous financial losses and high R&D expenses remain challenges. The sentiment is balanced between the achievements and ongoing challenges.
Q3-2025 Updates
Positive Updates
Completion of ECLIPSE 1 Enrollment
Successfully completed enrollment in ECLIPSE 1, the first registrational Phase III study for hepatitis delta, ahead of schedule. This positions the company well for regulatory submissions with top line data expected by early 2027.
Strong Financial Position
Ended the third quarter with approximately $810.7 million in cash, cash equivalents, and investments, with a projected cash runway extending into mid-2027.
Progress in Oncology Portfolio
Substantial progress in dose escalation for VIR-5500, a PSMA-targeted T-cell engager, with promising potential for future data updates expected in Q1 2026.
Cost Savings and Reduced Expenses
Year-over-year decrease in operating expenses by $46.2 million, driven by restructuring initiatives and lower licensing expenses.
Negative Updates
Continued Financial Losses
Reported a net loss of $163.1 million for the third quarter of 2025, though it was an improvement from the previous year's loss of $213.7 million.
High R&D Expenses
R&D expenses for the third quarter of 2025 were significant at $151.5 million, driven by milestone payments and increased clinical development expenses.
Dependence on Future Data
The success of upcoming programs heavily relies on future data updates, particularly for the VIR-5500 and other T-cell engager programs.
Company Guidance
During Vir Biotechnology's third quarter 2025 earnings call, the company provided detailed guidance on its clinical programs and financial outlook. Key highlights included the completion of enrollment in the ECLIPSE 1 Phase III study for hepatitis delta, with primary completion expected by Q4 2026 and top-line data by Q1 2027. The company plans to present a comprehensive data update for the VIR-5500 T-cell engager in Q1 2026. The call also discussed the initiation of a combination study in metastatic castration-resistant prostate cancer. Financially, Vir reported a net loss of $163.1 million for the quarter, with R&D expenses totaling $151.5 million. The company ended the quarter with $810.7 million in cash and investments, projecting a cash runway into mid-2027.

Vir Biotechnology Financial Statement Overview

Summary
Vir Biotechnology is facing significant financial challenges, with negative net profit margins, declining revenue growth, and ongoing cash flow issues. The balance sheet shows low leverage but negative returns on equity, indicating financial instability.
Income Statement
Vir Biotechnology's income statement shows significant challenges with negative net profit margins and declining revenue growth. The TTM data reveals a gross profit margin of 95.53%, but this is overshadowed by a net loss, indicating inefficiencies in cost management. The revenue growth rate is negative, reflecting a downturn in sales performance. Overall, the company is struggling to maintain profitability.
Balance Sheet
The balance sheet indicates a relatively low debt-to-equity ratio of 0.10, suggesting conservative leverage. However, the return on equity is negative, highlighting the company's inability to generate positive returns for shareholders. The equity ratio is stable, but the overall financial health is compromised by persistent losses.
Cash Flow
The cash flow statement shows negative operating and free cash flows, with a slight decline in free cash flow growth. The operating cash flow to net income ratio is negative, indicating cash flow challenges. The free cash flow to net income ratio is slightly above 1, suggesting some alignment between cash flow and reported earnings, but overall cash flow management remains a concern.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue16.86M74.20M86.18M1.62B1.10B67.25M
Gross Profit-438.52M-404.44M-486.65M994.83M581.54M67.25M
EBITDA-511.54M-508.91M-641.64M839.85M426.56M-291.54M
Net Income-499.65M-521.96M-615.06M515.84M528.58M-298.67M
Balance Sheet
Total Assets1.02B1.40B1.92B2.80B1.95B918.76M
Cash, Cash Equivalents and Short-Term Investments506.51M905.35M1.52B2.40B708.14M736.86M
Total Debt100.17M97.89M124.54M127.97M137.49M70.18M
Total Liabilities223.35M248.43M328.82M724.13M522.42M201.91M
Stockholders Equity796.10M1.15B1.59B2.08B1.43B716.85M
Cash Flow
Free Cash Flow-460.43M-453.65M-800.36M1.60B-69.41M-197.49M
Operating Cash Flow-453.54M-446.35M-778.78M1.66B-47.59M-190.94M
Investing Cash Flow364.46M499.37M164.73M-1.19B-140.81M-9.86M
Financing Cash Flow4.01M4.39M7.38M34.76M100.33M529.47M

Vir Biotechnology Technical Analysis

Technical Analysis Sentiment
Positive
Last Price5.96
Price Trends
50DMA
5.98
Positive
100DMA
5.65
Positive
200DMA
5.53
Positive
Market Momentum
MACD
-0.04
Positive
RSI
52.31
Neutral
STOCH
63.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VIR, the sentiment is Positive. The current price of 5.96 is below the 20-day moving average (MA) of 6.17, below the 50-day MA of 5.98, and above the 200-day MA of 5.53, indicating a neutral trend. The MACD of -0.04 indicates Positive momentum. The RSI at 52.31 is Neutral, neither overbought nor oversold. The STOCH value of 63.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for VIR.

Vir Biotechnology Risk Analysis

Vir Biotechnology disclosed 61 risk factors in its most recent earnings report. Vir Biotechnology reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Vir Biotechnology Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
$358.29M-7.54-43.11%-5.71%
61
Neutral
$1.14B-17.49-22.38%2147.20%-269.99%
59
Neutral
$1.00B-8.42-19.61%38.16%48.43%
54
Neutral
$1.01B-2.30-53.89%175.62%19.63%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$805.53M-49.06%-78.55%7.74%
46
Neutral
$874.10M-1.25-12.52%-82.84%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VIR
Vir Biotechnology
6.16
-5.94
-49.09%
XNCR
Xencor
14.95
-5.65
-27.43%
IOVA
Iovance Biotherapeutics
2.77
-3.63
-56.72%
AVXL
Anavex Life Sciences
4.10
-7.13
-63.49%
IVA
Inventiva
5.10
2.93
135.02%
SEPN
Septerna, Inc.
26.41
8.42
46.80%

Vir Biotechnology Corporate Events

Business Operations and StrategyProduct-Related Announcements
Vir Biotechnology Secures Licensing Deal with Norgine
Positive
Dec 16, 2025

On December 16, 2025, Vir Biotechnology entered into a license agreement with Norgine Pharma UK Limited, granting Norgine exclusive commercial rights to a combination treatment for chronic hepatitis delta (CHD) in Europe, Australia, and New Zealand. Vir will receive an initial EUR 55 million reimbursement and up to EUR 495 million in milestones, with shared clinical development costs for ongoing trials. The combination treatment of tobevibart and elebsiran showed promising results in a Phase 2 trial, achieving significant virologic suppression and being well-tolerated, which could enhance Vir’s market positioning and impact stakeholders positively.

The most recent analyst rating on (VIR) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on Vir Biotechnology stock, see the VIR Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 19, 2025