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Myriad Genetics (MYGN)
NASDAQ:MYGN
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Myriad Genetics (MYGN) AI Stock Analysis

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MYGN

Myriad Genetics

(NASDAQ:MYGN)

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Neutral 51 (OpenAI - 4o)
Rating:51Neutral
Price Target:
$8.00
▲(26.38% Upside)
Myriad Genetics faces significant financial challenges, particularly in profitability and cash flow management, which weigh heavily on its overall score. Technical analysis provides a moderately positive outlook, but valuation remains a concern due to ongoing losses. The company's strategic initiatives and operational efficiencies offer some optimism for future growth.
Positive Factors
Strategic Partnerships
This partnership enhances Myriad's capabilities in precision medicine, potentially expanding its market reach and strengthening its competitive position in the genetic testing industry.
Product Launches
New product launches are expected to drive growth by expanding Myriad's test offerings, potentially increasing market share and revenue in the competitive genetic testing market.
Operational Efficiency
High gross margins indicate effective cost management and operational efficiency, which can contribute to long-term profitability and financial stability.
Negative Factors
Profitability Challenges
Persistent profitability issues indicate difficulty in converting revenue into profit, which may hinder long-term financial health and investment capacity.
Cash Flow Issues
Negative cash flows suggest inefficiencies in cash generation, which can limit the company's ability to fund operations and invest in growth opportunities.
Revenue Decline
A decline in revenue signals potential market challenges and could impact the company's ability to sustain growth and profitability in the long term.

Myriad Genetics (MYGN) vs. SPDR S&P 500 ETF (SPY)

Myriad Genetics Business Overview & Revenue Model

Company DescriptionMyriad Genetics, Inc., a genetic testing and precision medicine company, develops and commercializes genetic tests in the United States and internationally. The company offers molecular diagnostic tests for use in oncology, and women's and mental health applications. It provides MyRisk Hereditary Cancer Test, a DNA sequencing test for assessing the risks for hereditary cancers; BRACAnalysis CDx Germline Companion Diagnostic Test, a DNA sequencing test to help determine the therapy for patients with metastatic breast, ovarian, metastatic pancreatic, or metastatic prostate cancer with deleterious or suspected deleterious germline BRCA variants; and MyChoice CDx Companion Diagnostic Test, a tumor test that determines homologous recombination deficiency status in patients with ovarian cancer. The company also offers Prolaris Prostate Cancer Prognostic Test, a RNA expression tumor analysis for assessing the aggressiveness of prostate cancer; EndoPredict Breast Cancer Prognostic Test, a RNA expression test for assessing the aggressiveness of breast cancer; Precise Tumor, a solution for precision oncology; and Prequel Prenatal Screen, a non-invasive prenatal screening test conducted using maternal blood to screen for severe chromosomal disorders in a fetus. In addition, it provides Foresight Carrier Screen, a prenatal test for future parents to assess their risk of passing on a recessive genetic condition to their offspring; and GeneSight Psychotropic Mental Health Medication Test, a DNA genotyping test to aid psychotropic drug selection for patients suffering from depression, anxiety, ADHD, and other mental health conditions. Myriad Genetics, Inc. has a strategic collaboration with Illumina, Inc. and Intermountain Precision Genomics for an offering of germline and somatic tumor testing services. The company was founded in 1991 and is headquartered in Salt Lake City, Utah.
How the Company Makes MoneyMyriad Genetics generates revenue primarily through the sale of its genetic testing services. The company operates a fee-for-service model, where healthcare providers order tests for patients, and Myriad bills the insurers or patients directly. Key revenue streams include the hereditary cancer testing segment, which assesses genetic mutations in patients to evaluate their cancer risk, and the myRisk test that evaluates multiple cancer types simultaneously. Additionally, Myriad earns income from its pharmacogenomic tests that help determine how patients metabolize certain medications, enhancing treatment efficacy. The company has also established significant partnerships with various healthcare organizations and payers, which facilitates broader access to its tests and enhances its market presence. Factors contributing to earnings include increasing awareness and demand for genetic testing, advancements in technology, and the growing emphasis on personalized medicine.

Myriad Genetics Earnings Call Summary

Earnings Call Date:Nov 03, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Neutral
The earnings call presented a mixed picture. While there were strong operational efficiencies and promising strategic initiatives that promise future growth, these were counterbalanced by current revenue declines and challenges in certain segments, notably prenatal testing. The company is taking proactive steps to address these challenges and remains optimistic about future prospects.
Q3-2025 Updates
Positive Updates
Strong Volume Growth in Key Segments
MyRisk in oncology saw a 16% volume growth year-over-year, and MyRisk for unaffected grew by 11%. GeneSight volume increased by 8%, showing acceleration from the first half of 2025.
High Adjusted Gross Margin
The company reported a strong adjusted gross margin of 70.1% in the third quarter, reflecting operational efficiency and strong test mix.
Strategic Partnerships and Product Launches
The company entered into a collaboration with SOPHiA GENETICS and is on track to launch the updated MyRisk test and a new Prolaris prostate cancer test in 2026. These initiatives are expected to accelerate growth.
Positive Adjusted EBITDA and Free Cash Flow
Reported an adjusted EBITDA of $10.3 million and adjusted free cash flow of $18.6 million, demonstrating the profitability and cash-generating potential of the business.
Reaffirmation of 2025 Financial Guidance
The company reaffirmed its full-year revenue guidance of $818 million to $828 million, with a gross margin range of 69.5% to 70% and adjusted EBITDA guidance of $27 million to $33 million.
Negative Updates
Revenue Decline
Total revenue for the third quarter was $205.7 million, a decline of 4% year-over-year, primarily due to a difficult comparison with the prior year and the impact of UnitedHealthcare's policy change on GeneSight coverage.
Average Revenue Per Test Decrease
Average revenue per test decreased by 7% year-over-year due to shifts in payer mix and the impact of UnitedHealthcare's policy change.
Challenges with Prenatal Testing
Volume growth for legacy prenatal products was flat year-over-year, indicating continued challenges in this segment despite some improvements from previous quarters.
Company Guidance
During the third quarter of 2025, Myriad Genetics reported revenue of $205.7 million, marking a 4% year-over-year decrease, although the underlying growth was 5% when adjusted for specific headwinds. The company achieved strong adjusted gross margins of 70.1% and an adjusted EBITDA of $10.3 million. Testing volumes grew 3%, with MyRisk oncology volumes increasing by 16% and GeneSight volumes by 8%. The company maintained a focus on profitability, with a disciplined approach to operating expenses, which decreased by $1 million year-over-year. Myriad Genetics reiterated its 2025 financial guidance, projecting annual revenue between $818 million and $828 million, and continued investments in its cancer care continuum strategy to drive future growth.

Myriad Genetics Financial Statement Overview

Summary
Myriad Genetics shows strong revenue growth but struggles with profitability and cash flow management. The company has a solid gross profit margin, but negative net margins and cash flows indicate ongoing operational and financial hurdles. Moderate leverage is present, but negative return on equity suggests inefficiencies in generating returns.
Income Statement
45
Neutral
Myriad Genetics shows a mixed performance in its income statement. The company has experienced a positive revenue growth rate of 19.2% in the TTM, indicating strong top-line growth. However, the company is struggling with profitability, as evidenced by negative net profit, EBIT, and EBITDA margins. The gross profit margin remains healthy at over 70%, but the significant negative net profit margin of -47.4% highlights ongoing challenges in controlling costs and achieving profitability.
Balance Sheet
50
Neutral
The balance sheet of Myriad Genetics reflects moderate leverage with a debt-to-equity ratio of 0.40 in the TTM, which is manageable. However, the return on equity is negative, indicating that the company is not generating profits from its equity base. The equity ratio is not explicitly provided, but the company's equity position appears stable relative to its assets.
Cash Flow
40
Negative
The cash flow statement reveals challenges in cash generation, with negative operating and free cash flows in the TTM. Despite a significant improvement in free cash flow growth, the operating cash flow to net income ratio is negative, indicating inefficiencies in converting income into cash. The free cash flow to net income ratio is positive, suggesting some ability to generate cash relative to net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue832.90M837.60M753.20M678.40M690.60M557.00M
Gross Profit586.70M585.40M517.00M476.40M493.00M378.80M
EBITDA-355.00M-59.50M-186.10M-67.80M14.10M-123.40M
Net Income-395.20M-127.30M-263.30M-112.00M-27.20M-223.70M
Balance Sheet
Total Assets677.30M1.03B1.15B1.20B1.32B1.42B
Cash, Cash Equivalents and Short-Term Investments74.40M102.40M140.90M114.90M339.80M150.70M
Total Debt154.60M140.30M152.10M145.00M92.30M0.00
Total Liabilities289.20M326.50M363.30M312.90M352.90M537.80M
Stockholders Equity388.10M701.10M783.20M885.80M967.80M881.00M
Cash Flow
Free Cash Flow-50.00M-38.40M-184.20M-151.60M600.00K-40.10M
Operating Cash Flow-22.60M-8.70M-110.90M-106.30M18.60M-26.90M
Investing Cash Flow-13.60M-11.90M31.90M-77.50M274.40M61.60M
Financing Cash Flow15.20M-7.40M152.90M-8.00M-150.60M-1.00M

Myriad Genetics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price6.33
Price Trends
50DMA
7.51
Negative
100DMA
6.35
Negative
200DMA
7.50
Negative
Market Momentum
MACD
-0.15
Positive
RSI
31.88
Neutral
STOCH
11.16
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MYGN, the sentiment is Negative. The current price of 6.33 is below the 20-day moving average (MA) of 7.74, below the 50-day MA of 7.51, and below the 200-day MA of 7.50, indicating a bearish trend. The MACD of -0.15 indicates Positive momentum. The RSI at 31.88 is Neutral, neither overbought nor oversold. The STOCH value of 11.16 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MYGN.

Myriad Genetics Risk Analysis

Myriad Genetics disclosed 50 risk factors in its most recent earnings report. Myriad Genetics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Myriad Genetics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$850.18M12.5924.11%14.46%
62
Neutral
$979.86M-2.69%10.15%-295.52%
61
Neutral
$700.33M-4.54%4.31%69.57%
53
Neutral
$1.31B-12.99%10.10%-44.29%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$602.16M-72.52%0.21%-233.51%
51
Neutral
$775.26M-43.69%-21.02%47.74%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MYGN
Myriad Genetics
6.33
-11.08
-63.64%
NEO
NeoGenomics
10.40
-5.37
-34.05%
CDNA
CareDx
15.01
-8.64
-36.53%
FLGT
Fulgent Genetics
22.31
2.88
14.82%
PSNL
Personalis
7.18
2.63
57.80%
CSTL
Castle Biosciences
33.55
0.26
0.78%

Myriad Genetics Corporate Events

Myriad Genetics Reports Q3 2025 Financial Results
Nov 4, 2025

Myriad Genetics is a prominent player in the molecular diagnostic testing and precision medicine industry, offering a range of tests that assess disease risk and guide treatment decisions. In its third quarter of 2025, Myriad Genetics reported a revenue of $205.7 million, marking a 4% decrease from the previous year, although revenue remained stable when excluding specific headwinds. The company saw growth in hereditary cancer testing, with revenue and volume increasing by 3% and 11% year-over-year, respectively, and maintained a gross margin of 69.9%. Despite a GAAP net loss of $27.4 million, the adjusted earnings per share broke even, and adjusted EBITDA was reported at $10.3 million. A notable strategic move was the collaboration with SOPHiA GENETICS to develop a global liquid biopsy companion diagnostic testing solution. Myriad Genetics also highlighted its efforts to enhance profitability by focusing on the Cancer Care Continuum and implementing organizational changes to improve customer experience and market share. Looking ahead, Myriad Genetics remains committed to its financial guidance for 2025, aiming to continue its strategic initiatives and maintain its position in the industry.

Myriad Genetics Advances in Metastatic Cancer Treatment Study
Oct 27, 2025

Myriad Genetics (MYGN) is collaborating on a clinical study titled SHARON: Study of Metastatic Cancers in Patients With a Defect in a Homologous Recombination Gene Using Autologous Stems Cells and Potentiated Redox Cycling to Overcome Drug Resistance to Nitrogen Mustard Derivatives. The study aims to evaluate the safety of a novel treatment for metastatic cancer in patients with BRCA1, BRCA2, or PALB2 mutations, which could significantly impact treatment options for these genetic conditions.

Executive/Board Changes
Myriad Genetics Finalizes CFO Separation Agreement
Neutral
Oct 7, 2025

On October 1, 2025, Myriad Genetics entered into a Separation Agreement with its former CFO, Scott J. Leffler, following his departure on August 15, 2025, and official separation on September 2, 2025. The agreement, effective October 9, 2025, includes a severance payment of $1,239,384 and accelerated vesting of equity awards, reflecting the company’s adherence to standard executive transition practices and potentially impacting its financials and leadership dynamics.

The most recent analyst rating on (MYGN) stock is a Hold with a $6.00 price target. To see the full list of analyst forecasts on Myriad Genetics stock, see the MYGN Stock Forecast page.

Executive/Board Changes
Myriad Genetics Announces Leadership Change in Accounting
Neutral
Oct 3, 2025

On September 29, 2025, Myriad Genetics announced the resignation of Natalie Munk, their Senior Vice President and Chief Accounting Officer, effective October 24, 2025. Her departure was not due to any disagreements with the company. In response, the company appointed Benjamin R. Wheeler, their current Chief Financial Officer, as the new principal accounting officer effective upon Munk’s departure. Wheeler, who has been with the company for over thirteen years in various financial roles, will not receive additional compensation for this new designation.

The most recent analyst rating on (MYGN) stock is a Hold with a $6.00 price target. To see the full list of analyst forecasts on Myriad Genetics stock, see the MYGN Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Myriad Genetics Appoints Ben R. Wheeler as CFO
Positive
Aug 18, 2025

On August 18, 2025, Myriad Genetics announced the appointment of Ben R. Wheeler as the new Chief Financial Officer, effective August 16, 2025, following the departure of Scott J. Leffler from the role. Wheeler, who has been with the company for over 13 years, brings extensive financial expertise and leadership experience, which is expected to support Myriad’s growth strategy. The company also reaffirmed its financial guidance for the full year 2025, indicating confidence in its strategic direction.

The most recent analyst rating on (MYGN) stock is a Buy with a $29.00 price target. To see the full list of analyst forecasts on Myriad Genetics stock, see the MYGN Stock Forecast page.

Myriad Genetics’ Earnings Call: Growth Amid Challenges
Aug 7, 2025

Myriad Genetics’ recent earnings call conveyed a generally positive sentiment, underscored by robust revenue growth, profitability, and strategic partnerships. Despite challenges, such as UnitedHealthcare’s coverage decision impacting GeneSight and issues in prenatal testing, the company demonstrated confidence by raising its guidance for 2025, signaling a strong strategic direction.

Myriad Genetics Updates 2025 Revenue Guidance Amid Growth
Aug 6, 2025

Myriad Genetics is a prominent company in the molecular diagnostic testing and precision medicine sector, focusing on developing tests that assess disease risk and guide treatment decisions across various medical specialties. The company recently reported its second quarter 2025 financial results, highlighting a slight revenue increase and an updated revenue guidance for the year. Despite a GAAP net loss due to impairment charges, Myriad Genetics saw growth in its hereditary cancer testing and improved gross margins.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 04, 2025