Revenue within Guidance
Q1 revenue of $200.4 million, up ~2% year-over-year and within the company's Q1 guidance range; management reaffirmed full-year revenue guidance of $860M–$880M.
Strong Hereditary Cancer Testing Growth
Hereditary cancer testing volume grew 14% year-over-year (accelerating from 11% in Q4). Affected population volume grew ~10% YoY and unaffected population volume grew ~16% YoY, delivering market share gains.
GeneSight (Mental Health) Momentum
GeneSight revenue of $38.3 million, up 24% year-over-year, with test volume up 7% YoY; ordering base reached a record >39,000 clinicians and reimbursement improvements (biomarker legislation) lifted ASPs and revenue.
Healthy Gross Margin Profile
Reported adjusted gross margin of ~68.7%–69% in Q1 (roughly +20 basis points YoY), in line with full-year guidance and supporting ongoing strategic investments.
Pipeline and New Product Progress
Multiple launches on track: Precise MRD (alpha launch for breast in March) showing promising early adoption and assay performance; Prolaris+AI on track to launch in June; FirstGene in early access with strong CONNECTOR enrollment and a planned full commercial launch in H2 2026. Precise MRD sensitivity reported to detect down to 1 part per million.
Commercial Expansion and Investments
Expanded commercial team by over 100 account executives year-over-year and committed ~$35 million of investment over the next several years to strengthen commercial capabilities, demand generation and launch execution to support back-half acceleration.
Operational and Balance Sheet Strength
MRD assay yields and turnaround times tracking to internal targets; company reports access to $199 million in capital and reaffirmed adjusted EBITDA target range of $37M–$49M for 2026.
Average Revenue Per Test Improvement
Average revenue per test improved ~2% year-over-year in Q1, driven by product mix (hereditary cancer growth) and improved reimbursement in GeneSight.