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CareDx Inc (CDNA)
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CareDx (CDNA) AI Stock Analysis

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CDNA

CareDx

(NASDAQ:CDNA)

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Outperform 77 (OpenAI - 4o)
Rating:77Outperform
Price Target:
$17.50
▲(16.59% Upside)
CareDx's strong financial performance and positive earnings call are the most significant factors driving the score. The company's robust revenue growth, improved profitability, and strategic initiatives are complemented by a favorable valuation. Technical indicators support a bullish outlook, although operational efficiency and market conditions for transplant volumes require attention.
Positive Factors
Revenue Growth
Strong revenue growth indicates expanding market reach and effective product adoption, supporting long-term business sustainability and competitive positioning.
Cash Flow Generation
Robust cash flow generation enhances financial flexibility, enabling strategic investments and supporting ongoing operations, crucial for sustained growth.
Product Innovation
Innovative product launches like HistoMap Kidney strengthen CareDx's market position and expand its diagnostic portfolio, driving future revenue streams.
Negative Factors
Operational Efficiency Challenges
Operational inefficiencies can hinder profitability and limit the company's ability to scale effectively, impacting long-term financial health.
Flat Transplant Volumes
Flat transplant volumes may limit growth potential in core markets, affecting revenue expansion and market share in the transplant diagnostics sector.
IOTA Program Challenges
Challenges with the IOTA program could delay expected growth in kidney transplant diagnostics, impacting strategic objectives and revenue forecasts.

CareDx (CDNA) vs. SPDR S&P 500 ETF (SPY)

CareDx Business Overview & Revenue Model

Company DescriptionCareDx, Inc. is a leading precision medicine company focused on transplant medicine, specializing in developing and providing diagnostic solutions for organ transplant patients. The company operates primarily in the healthcare sector, offering products and services that enhance patient care and improve transplant outcomes. CareDx's core products include AlloSure, a non-invasive blood test that assesses kidney transplant rejection, and AlloMap, a gene expression profiling test used to monitor heart transplant patients.
How the Company Makes MoneyCareDx generates revenue primarily through the sale of its diagnostic testing services. The company charges healthcare providers for its proprietary tests, which are ordered for transplant patients to assess organ health and rejection risk. Key revenue streams include direct sales of testing services, which are often reimbursed by insurance providers, and partnerships with transplant centers and healthcare organizations that integrate CareDx's services into their patient care protocols. Additionally, CareDx may engage in collaborations with pharmaceutical companies for clinical trials and research, further diversifying its revenue opportunities.

CareDx Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 04, 2026
Earnings Call Sentiment Positive
The earnings call reflected a strong quarter with significant revenue growth and operational improvements, including successful product launches and strategic initiatives. However, the overall market conditions for transplant volumes have been flat, and the expected impact from the IOTA program has not yet been realized.
Q3-2025 Updates
Positive Updates
Strong Revenue Growth
Total revenue of $100.1 million grew 21% year-over-year, with all three business segments generating record quarterly revenue.
Improved EBITDA and Share Repurchase
Adjusted EBITDA was $15.3 million, more than double Q3 last year. The company repurchased an additional 2 million shares during the quarter.
Launch of HistoMap Kidney
CareDx launched HistoMap Kidney, a breakthrough tissue-based molecular test, at the American Society of Nephrology meeting.
Revenue Cycle Management Success
The company achieved over 200% improvement in total appeals volume and a 60% improvement in claims submission time, with cash collections accelerating to 124% of testing services revenue.
EPIC Integration Enhancements
EPIC Aura integration projects are in process, with positive feedback from the Boston Children's pilot, leading to a 20% reduction in order turnaround time.
Negative Updates
Flat Transplant Volumes
Transplant volumes across all three solid organs remained relatively flat year-over-year, impacting expected growth.
Challenges with IOTA Program Impact
The anticipated acceleration in kidney transplant volumes from the IOTA program has not materialized as expected.
Company Guidance
During the CareDx Third Quarter 2025 Financial Results Conference Call, the company provided updated guidance reflecting strong performance. Total revenue for the third quarter reached $100.1 million, marking a 21% year-over-year increase, with Testing Services revenue at $72.2 million and delivering approximately 50,300 tests. CareDx raised its full-year 2025 revenue guidance to a range of $372 million to $376 million and adjusted EBITDA guidance to $35 million to $39 million, highlighting significant operational improvements. The company also reported a 13% year-over-year increase in test volume and a 5% increase in revenue per test, driven by enhanced revenue cycle management. Additionally, CareDx emphasized its focus on innovation and customer engagement, with new product launches such as HistoMap Kidney and strategic appointments to strengthen its leadership team.

CareDx Financial Statement Overview

Summary
CareDx's financial performance is mixed. The company is profitable with a positive net profit margin, but revenue and cash flow growth are declining. The balance sheet is stable with low leverage, but the decrease in equity ratio could pose a risk. Operational challenges are evident in negative EBIT and EBITDA margins, requiring attention to improve efficiency.
Income Statement
72
Positive
CareDx's income statement shows a mixed performance. The company has a positive net profit margin of 15.16% in the TTM, indicating profitability. However, revenue growth is negative at -1.62%, suggesting a decline in sales. The gross profit margin has decreased from previous years, and EBIT and EBITDA margins are negative, reflecting operational challenges.
Balance Sheet
68
Positive
The balance sheet is relatively stable with a low debt-to-equity ratio of 0.07, indicating low leverage. Return on equity is positive at 15.22%, showing effective use of equity to generate profits. However, the equity ratio has decreased over time, which may indicate a reduction in financial stability.
Cash Flow
75
Positive
Cash flow analysis reveals a decline in free cash flow growth at -28.93% in the TTM, which is a concern. The operating cash flow to net income ratio is low at 0.19, suggesting limited cash generation from operations. However, the free cash flow to net income ratio is healthy at 1.01, indicating that the company is generating sufficient free cash flow relative to its net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue358.00M333.79M280.32M321.79M296.40M192.19M
Gross Profit241.44M224.16M178.32M209.58M199.01M129.08M
EBITDA-17.17M-33.99M-84.92M-61.22M-17.84M-8.17M
Net Income60.76M52.55M-190.28M-76.61M-30.66M-18.71M
Balance Sheet
Total Assets432.31M491.05M466.83M542.99M566.62M368.51M
Cash, Cash Equivalents and Short-Term Investments194.22M260.65M235.42M293.09M348.49M224.70M
Total Debt27.64M28.37M34.22M39.00M21.35M18.10M
Total Liabilities121.17M112.62M205.50M112.08M100.75M90.83M
Stockholders Equity311.14M378.43M261.33M430.91M465.88M277.68M
Cash Flow
Free Cash Flow37.09M31.56M-27.63M-49.57M-39.55M23.07M
Operating Cash Flow42.56M38.05M-18.39M-25.24M-19.29M33.43M
Investing Cash Flow34.96M-483.00K40.45M-228.50M47.71M-100.39M
Financing Cash Flow-81.83M-5.61M-29.61M-4.54M185.64M163.15M

CareDx Technical Analysis

Technical Analysis Sentiment
Positive
Last Price15.01
Price Trends
50DMA
15.37
Positive
100DMA
14.46
Positive
200DMA
16.56
Positive
Market Momentum
MACD
0.73
Negative
RSI
65.50
Neutral
STOCH
87.42
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CDNA, the sentiment is Positive. The current price of 15.01 is below the 20-day moving average (MA) of 16.24, below the 50-day MA of 15.37, and below the 200-day MA of 16.56, indicating a bullish trend. The MACD of 0.73 indicates Negative momentum. The RSI at 65.50 is Neutral, neither overbought nor oversold. The STOCH value of 87.42 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CDNA.

CareDx Risk Analysis

CareDx disclosed 66 risk factors in its most recent earnings report. CareDx reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CareDx Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
$883.61M14.4124.11%14.46%
60
Neutral
$914.39M-3.80%13.60%74.64%
60
Neutral
$1.17B-2.69%10.15%-295.52%
57
Neutral
$952.87M-43.69%-21.02%47.74%
55
Neutral
$1.57B-12.99%10.10%-44.29%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$711.22M-72.52%0.21%-233.51%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CDNA
CareDx
17.87
-7.77
-30.30%
MYGN
Myriad Genetics
7.63
-9.06
-54.28%
NEO
NeoGenomics
12.10
-5.90
-32.78%
FLGT
Fulgent Genetics
29.58
10.01
51.15%
PSNL
Personalis
10.73
6.83
175.13%
CSTL
Castle Biosciences
39.95
8.55
27.23%

CareDx Corporate Events

CareDx Inc. Reports Strong Q3 Earnings Growth
Nov 6, 2025

In the recent earnings call, CareDx Inc. reported a robust quarter marked by substantial revenue growth and operational enhancements. The company celebrated successful product launches and strategic initiatives, although it acknowledged the flat market conditions for transplant volumes and the unrealized impact from the IOTA program.

CareDx Reports Strong Q3 2025 Financial Results
Nov 5, 2025

CareDx, Inc., headquartered in Brisbane, California, is a precision medicine company specializing in the development and commercialization of healthcare solutions for transplant patients and caregivers, offering genomics-based information and digital healthcare solutions.

Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresProduct-Related Announcements
CareDx Reports Strong Q3 Financial Results
Positive
Nov 4, 2025

On November 4, 2025, CareDx announced its third-quarter financial results, highlighting a 21% year-over-year revenue increase to $100.1 million, driven by a 19% rise in testing services revenue and a 13% growth in testing services volume. The company reported a GAAP net income of $1.7 million, a significant improvement from the previous year’s loss, and raised its 2025 revenue guidance to $372 million to $376 million. Recent strategic moves include appointing new leadership, publishing studies, and launching innovative products, reinforcing its market leadership in transplant care.

The most recent analyst rating on (CDNA) stock is a Hold with a $15.50 price target. To see the full list of analyst forecasts on CareDx stock, see the CDNA Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
CareDx Appoints Suresh Gunasekaran as New Director
Positive
Oct 24, 2025

On October 22, 2025, CareDx, Inc. appointed Suresh Gunasekaran as a Class II director. Mr. Gunasekaran, with extensive experience in healthcare leadership, will receive compensation in cash and restricted stock units as part of his non-employee director role. This appointment may enhance CareDx’s strategic direction and governance with Mr. Gunasekaran’s expertise.

The most recent analyst rating on (CDNA) stock is a Hold with a $15.50 price target. To see the full list of analyst forecasts on CareDx stock, see the CDNA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 10, 2025