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CareDx (CDNA)
NASDAQ:CDNA
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CareDx (CDNA) AI Stock Analysis

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CDNA

CareDx

(NASDAQ:CDNA)

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Outperform 71 (OpenAI - 5.2)
Rating:71Outperform
Price Target:
$32.00
▲(49.39% Upside)
Action:Reiterated
Date:06/19/26
The score is driven primarily by improving fundamentals (strong cash generation, low leverage, re-accelerating revenue, and solid gross margins) and constructive guidance/actions from the latest earnings call (raised outlook and portfolio simplification). Technicals are supportive but near-overbought conditions add risk. Valuation remains a headwind due to negative P/E tied to inconsistent GAAP profitability.
Positive Factors
Recurring transplant diagnostics platform
CareDx's core business is recurring, clinically necessary surveillance testing and transplant-focused digital services. These diagnostic workflows (tests, software, support) create stickiness with transplant centers and predictable per-patient demand, supporting stable revenue streams over months to years as adoption grows.
Negative Factors
Inconsistent GAAP profitability
Despite revenue and cash-flow improvements, recurring GAAP losses and negative operating profit indicate earnings conversion is not yet durable. Continued volatility in reported profitability could limit reinvestment capacity and make achieving sustained GAAP profits dependent on execution and cost control.
Read all positive and negative factors
Positive Factors
Negative Factors
Recurring transplant diagnostics platform
CareDx's core business is recurring, clinically necessary surveillance testing and transplant-focused digital services. These diagnostic workflows (tests, software, support) create stickiness with transplant centers and predictable per-patient demand, supporting stable revenue streams over months to years as adoption grows.
Read all positive factors

CareDx Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Shows how the company’s sales break down across its different business lines (for example diagnostics, lab services, and recurring testing or monitoring). That split reveals which parts of the business are driving growth, which produce steadier, subscription-like income, and which are more exposed to reimbursement changes, competition, or single-customer concentration—key for judging future revenue stability and upside potential.
Chart InsightsTesting Services rebounded sharply from a 2023 trough and is again the revenue engine, but recent upside reflects higher revenue-per-test and much better collections rather than a clear transplant-volume boom; CareDx raised 2025 guidance on this operational leverage. Meanwhile Product and Patient & Digital Solutions are the fastest-growing pieces, diversifying revenue and adding higher-margin, innovation-led upside (e.g., HistoMap Kidney, EPIC integrations). Key risk: transplant volumes remain largely flat and IOTA benefits haven’t materialized, so future growth depends on market share, pricing mix, and continued RCM gains.
Data provided by:The Fly

CareDx (CDNA) vs. SPDR S&P 500 ETF (SPY)

CareDx Business Overview & Revenue Model

Company Description
CareDx, Inc. is a global innovator specializing in the discovery, development, and commercialization of diagnostic and management tools designed for transplant recipients and their healthcare providers. The company's extensive portfolio features a...
How the Company Makes Money
CareDx primarily makes money by providing diagnostic testing and related services to transplant centers and clinicians, with revenue recognized when tests are performed and reported. A core revenue stream comes from its transplant diagnostics port...

CareDx Earnings Call Summary

Earnings Call Date:Apr 28, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Jul 30, 2026
Earnings Call Sentiment Positive
The call communicated strong top-line growth, substantial margin and EBITDA improvement, raised full‑year guidance, a strategic simplification via a Lab Products divestiture (expected ~$160M net proceeds), and a targeted acquisition (Navaris) that expands addressable markets with strong clinical evidence and favorable reimbursement. Challenges include modest profitability and declining trends in the Lab Products segment prior to divestiture, revenue recognition timing noise, reimbursement/LCD risk (~$7.5M modeled headwind), elevated operating expenses and uncertainty in transplant procedure volumes, and integration/scale risks for Navaris and the product carve-out. On balance, the positive growth, improved profitability, cash position, and strategic actions outweigh the execution and timing risks discussed on the call.
Positive Updates
Strong Q1 Revenue and Volume Growth
Total revenue increased 39% year-over-year to $118.0M in Q1 2026; testing volume rose 17% to 54,900 tests.
Negative Updates
Lab Products Segment Weakness and Low Profitability
Lab products revenue declined 4% in Q1 to $10M; the Products business generated approximately $10M of revenue and less than $1M adjusted EBITDA in the period; full-year products EBITDA contribution estimated only $3M–$9M, underscoring low margin profile prior to divestiture.
Read all updates
Q1-2026 Updates
Negative
Strong Q1 Revenue and Volume Growth
Total revenue increased 39% year-over-year to $118.0M in Q1 2026; testing volume rose 17% to 54,900 tests.
Read all positive updates
Company Guidance
CareDx raised 2026 guidance to $447–$465M in revenue ($456M midpoint, +20% YoY) and adjusted EBITDA of $43–$57M ($50M midpoint, +58% YoY), with testing volume expected at 224k–229k tests (226.5k midpoint, +13% YoY). Management guided testing services revenue of $337–$351M ($344M midpoint, +25% YoY), patient & digital revenue $63–$66M ($65M midpoint, +13% YoY) and lab products revenue $45–$50M ($48M midpoint, flat), forecasting ~10% YoY revenue-per-test growth (7% from higher accruals, 3% from cash collection/receivable timing, and a $7.5M estimated LCD headwind), average accrual rising to $14.60/test by year‑end, out‑of‑period revenue of $7.5M in Q2 and $5M in Q3, modeled quarterly gross margins of ~68–71%, full‑year depreciation in operating expenses of ~$9M, operating expenses of $68–$70M (including roughly $2M incremental quarterly bonus accrual), a Board‑authorized $100M buyback (24 months), and an expected ~$160M net cash from the Lab Products divestiture at close (targeted by end of Q3).

CareDx Financial Statement Overview

Summary
Revenue is re-accelerating in TTM (+8.7%) with strong, stable gross margin (~67%). Balance sheet leverage is low (debt-to-equity ~0.06 TTM), and cash flow has improved materially (TTM operating cash flow ~$72.9M; free cash flow ~$65.2M; FCF growth +78.8%). The key drag is inconsistent profitability (TTM net margin ~-5.6% and operating profit negative), raising questions about durability of earnings conversion.
Income Statement
56
Neutral
Balance Sheet
78
Positive
Cash Flow
83
Very Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue412.82M379.81M333.79M280.32M321.79M296.40M
Gross Profit283.04M254.43M224.16M178.32M209.58M199.01M
EBITDA10.70M-667.00K-33.99M-84.92M-60.23M-20.20M
Net Income-8.19M-21.35M52.55M-190.28M-76.61M-30.66M
Balance Sheet
Total Assets411.06M413.23M491.05M466.83M542.99M566.62M
Cash, Cash Equivalents and Short-Term Investments187.18M177.21M260.65M235.42M293.09M348.49M
Total Debt24.50M26.19M28.37M34.22M39.00M21.35M
Total Liabilities97.53M110.13M112.62M205.50M112.08M100.75M
Stockholders Equity313.54M303.10M378.43M261.33M430.91M465.88M
Cash Flow
Free Cash Flow65.19M36.12M31.56M-27.63M-49.57M-39.55M
Operating Cash Flow72.95M42.03M38.05M-18.39M-25.24M-19.29M
Investing Cash Flow11.89M2.16M-483.00K40.45M-228.50M47.71M
Financing Cash Flow-95.66M-93.39M-5.61M-29.61M-4.54M185.64M

CareDx Technical Analysis

Technical Analysis Sentiment
Positive
Last Price21.42
Price Trends
50DMA
22.35
Positive
100DMA
20.28
Positive
200DMA
18.68
Positive
Market Momentum
MACD
1.56
Negative
RSI
74.13
Negative
STOCH
94.30
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CDNA, the sentiment is Positive. The current price of 21.42 is below the 20-day moving average (MA) of 24.06, below the 50-day MA of 22.35, and above the 200-day MA of 18.68, indicating a bullish trend. The MACD of 1.56 indicates Negative momentum. The RSI at 74.13 is Negative, neither overbought nor oversold. The STOCH value of 94.30 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CDNA.

CareDx Risk Analysis

CareDx disclosed 66 risk factors in its most recent earnings report. CareDx reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CareDx Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
$1.49B-185.20-2.61%19.17%-111.99%
67
Neutral
$737.02M-56.62-2.77%-2.06%-169.07%
59
Neutral
$1.85B-3.72-11.82%10.95%-26.52%
55
Neutral
$1.36B-13.48-43.52%-24.71%21.16%
54
Neutral
$566.88M-8.63-6.70%9.54%-79.16%
52
Neutral
$555.36M-1.36-109.09%-0.28%-286.80%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CDNA
CareDx
29.28
9.74
49.85%
MYGN
Myriad Genetics
5.85
0.54
10.17%
NEO
NeoGenomics
14.25
6.94
94.94%
FLGT
Fulgent Genetics
20.53
0.65
3.27%
PSNL
Personalis
13.75
7.19
109.60%
CSTL
Castle Biosciences
24.32
3.90
19.10%

CareDx Corporate Events

Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
CareDx Shareholders Back Directors, Auditor and Equity Plan
Positive
Jun 15, 2026
On June 11, 2026, CareDx, Inc. held its 2026 annual meeting of stockholders, where investors elected five directors to one-year terms and ratified Deloitte Touche LLP as the company’s independent auditor for the fiscal year ending December ...
Business Operations and StrategyStock BuybackFinancial DisclosuresM&A Transactions
CareDx to Acquire Naveris, Expanding Oncology Diagnostics
Positive
Apr 28, 2026
On April 28, 2026, CareDx agreed to acquire circulating tumor DNA specialist Naveris for $160 million in cash plus up to $100 million in revenue-based earnouts, with Naveris to become a wholly owned subsidiary subject to standard regulatory and cl...
Business Operations and StrategyFinancial DisclosuresM&A Transactions
CareDx Divests Lab Products to Refocus on Core Growth
Positive
Apr 16, 2026
On April 15, 2026, CareDx agreed to sell its Swedish subsidiary CareDx AB and its global Lab Products business, which includes HLA typing and post-transplant monitoring IVD kits, to Eurobio Scientific for $170 million in cash, subject to customary...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 19, 2026