Financial PerformanceThe Q3 operating expenses were increased to $1.2B, resulting in a larger unadjusted GAAP EPS loss.
Sales ProjectionsThe probability of success for mRNA-1647 in congenital CMV has been lowered to 0%, significantly impacting future sales projections.
Vaccine DevelopmentThe Phase 3 pivotal study of mRNA-1647 (CMV vaccine) did not meet its primary efficacy endpoint of preventing CMV infection, leading to the discontinuation of congenital CMV development.