Clinical Trials And EfficacyJNJ-2113's Phase 2b PsO data show efficacy better than any available oral therapy and equivalent to injectables, indicating a high probability of success for the four Phase 3 studies.
Market OpportunitiesRusfertide for Polycythemia Vera (PV) represents a $2 billion market opportunity, with promising Phase 2 data showing strong clinical benefit and attracting a collaboration with Takeda with a $300 million upfront payment.
Partnerships And Financial PotentialJNJ-2113 is an oral IL-23 receptor inhibitor co-developed with J&J in an agreement worth $967.5MM of milestones, plus 6-10% royalties.