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Inspire Medical Systems (INSP)
NYSE:INSP
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Inspire Medical Systems (INSP) AI Stock Analysis

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INSP

Inspire Medical Systems

(NYSE:INSP)

Rating:58Neutral
Price Target:
$97.00
▲(5.09% Upside)
The overall stock score is primarily influenced by strong financial performance and positive corporate events. However, technical analysis indicates bearish trends, and valuation concerns due to a high P/E ratio weigh down the score. Mixed earnings call sentiment also impacts the overall assessment.
Positive Factors
Procedure Efficiency
Inspire 5 procedure efficiency is expected to support volume and sales growth acceleration.
Sales Growth
INSP reported 2Q25 sales slightly ahead of consensus, with adjusted EBITDA margin significantly above expectations.
Valuation Levels
INSP looks increasingly attractive at current levels, trading near trough valuation levels after significant underperformance.
Negative Factors
Execution and Demand Issues
Investors will struggle to separate ongoing logistics and execution issues from underlying demand issues, and while management guided to an acceleration in 2026 sales, investors do not expect to give them credit for that just yet.
Growth Outlook
The downgrade to HOLD is due to a lower growth outlook and reduced revenue and EPS forecasts.
Guidance and Market Concerns
Inspire provided a disappointing update on its 2Q25 call as a significant cut to 2025E guidance took center stage amid worsening concerns around the health of the company’s underlying markets.

Inspire Medical Systems (INSP) vs. SPDR S&P 500 ETF (SPY)

Inspire Medical Systems Business Overview & Revenue Model

Company DescriptionInspire Medical Systems, Inc. is a medical technology company focused on developing innovative solutions for patients suffering from obstructive sleep apnea (OSA). The company is primarily engaged in the design and commercialization of its flagship product, the Inspire therapy system, which is a surgically implanted device that stimulates the hypoglossal nerve to maintain an open airway during sleep. Inspire operates within the healthcare sector, targeting both patients and healthcare providers, aiming to enhance treatment options for sleep apnea beyond traditional CPAP devices.
How the Company Makes MoneyInspire Medical Systems generates revenue primarily through the sale of its Inspire therapy system, which includes the implantation device and related components. The company also earns income from the ongoing sale of accessories and follow-up care associated with the therapy. Revenue is driven by hospital and surgical center partnerships where the Inspire system is implemented, and the company often collaborates with healthcare professionals to promote and educate about the benefits of its therapy. Additionally, reimbursement from insurance providers plays a crucial role in the company's earnings, as it allows patients to afford the therapy, thereby expanding the potential customer base.

Inspire Medical Systems Earnings Call Summary

Earnings Call Date:Aug 04, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 04, 2025
Earnings Call Sentiment Neutral
The earnings call reflected a mixed sentiment with several positive highlights, including revenue growth and clinical study success; however, these were offset by significant lowlights, such as reduced guidance, EPS decrease, rollout challenges for Inspire V, and increased operating expenses.
Q2-2025 Updates
Positive Updates
Revenue Growth
Total revenue for the second quarter was $217.1 million, an 11% increase from the $195.9 million generated in the second quarter of 2024. U.S. revenue increased by 10%, and revenue outside the U.S. increased by 23% year-over-year.
Adjusted EBITDA Increase
Adjusted EBITDA for the quarter totaled $44.1 million, which is a 14% increase compared to $38.7 million in the prior year period.
Medicare Reimbursement Proposal
CMS proposed a positive increase for Medicare reimbursement for the Inspire system, with the national average Medicare hospital reimbursement for CPT code 64568 proposed to increase by 4% and ASC reimbursement by 5%.
Clinical Study Success
Early results from the Singapore clinical study demonstrated a 20% reduction in surgical times, with U.S. centers experiencing a more than 20% increase in patient implants in the first half of 2025.
Negative Updates
Guidance Revision
Full year revenue guidance was adjusted to a range of $900 million to $910 million from the previous guidance of $940 million to $955 million, a 4% reduction at the midpoint.
Earnings Per Share Decrease
Diluted net income per share was reduced to a range of $0.40 to $0.50 from the previous guidance of $2.20 to $2.30 per share.
Challenges with Inspire V Rollout
Encountered headwinds in the rollout of the Inspire V system, including delays in training and onboarding, as well as implementation issues with SleepSync, affecting transition efforts.
Inventory and Medicare Billing Issues
Majority of units sold were Inspire IV, leading to inventory challenges. Additionally, Medicare billing for Inspire V was delayed until July 1, affecting patient treatment options.
Increased Operating Expenses
Total operating expenses for the quarter were $185.7 million, a 15% increase compared to the second quarter of 2024, attributed to expansion and increased corporate costs.
Company Guidance
During the Inspire Medical Systems second quarter 2025 conference call, CEO Tim Herbert provided an updated financial outlook, highlighting a revised full-year revenue guidance of $900 million to $910 million, down from the previous $940 million to $955 million, reflecting a 12% to 13% growth over 2024. This adjustment was attributed to challenges in transitioning customers to the Inspire V system, delays in Medicare billing software updates, and a slower rollout of SleepSync, which affected the commercial adoption of Inspire V. The company's diluted net income per share guidance was also adjusted to $0.40 to $0.50, down from $2.20 to $2.30, due to the revenue guidance change and increased marketing costs. Despite these headwinds, Herbert expressed confidence in the company's recovery strategy, including increased marketing efforts and expansion of its footprint, aiming for an accelerated growth trajectory in 2026.

Inspire Medical Systems Financial Statement Overview

Summary
Inspire Medical Systems demonstrates strong revenue growth and efficient cost management, reflected in its high gross profit margins. The company maintains a robust balance sheet with low leverage, enhancing its financial stability. While cash flow metrics show positive trends, there is room for improvement in converting net income into free cash flow.
Income Statement
75
Positive
Inspire Medical Systems has shown consistent revenue growth with a TTM revenue growth rate of 2.52%. The company maintains a strong gross profit margin of 84.47% in TTM, indicating efficient cost management. However, the net profit margin is relatively low at 6.17%, suggesting room for improvement in profitability. The EBIT and EBITDA margins have improved over the years, reflecting better operational efficiency.
Balance Sheet
80
Positive
The company has a solid balance sheet with a low debt-to-equity ratio of 0.048, indicating low leverage and financial stability. The return on equity is positive at 7.87% in TTM, showing effective use of equity to generate profits. The equity ratio is strong, reflecting a healthy capital structure with a significant portion of assets financed by equity.
Cash Flow
70
Positive
Inspire Medical Systems exhibits a positive trend in free cash flow growth, with a 7.81% increase in TTM. The operating cash flow to net income ratio is 1.26, indicating good cash generation relative to net income. However, the free cash flow to net income ratio of 0.72 suggests that not all net income is translating into free cash flow, which could be a point of concern.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue861.31M802.80M624.80M407.86M233.39M115.38M
Gross Profit727.54M679.82M528.22M341.74M200.12M97.76M
EBITDA81.21M65.03M-17.06M-39.69M-38.62M-53.16M
Net Income53.12M53.51M-21.15M-44.88M-42.04M-57.20M
Balance Sheet
Total Assets802.19M808.38M676.81M564.88M295.08M281.19M
Cash, Cash Equivalents and Short-Term Investments300.89M445.55M460.38M451.41M214.47M234.36M
Total Debt33.06M31.79M24.85M8.87M34.09M30.63M
Total Liabilities124.38M118.69M104.30M68.87M66.04M51.44M
Stockholders Equity677.81M689.70M572.51M496.01M229.05M229.75M
Cash Flow
Free Cash Flow85.01M91.12M1.02M2.47M-24.79M-55.50M
Operating Cash Flow117.44M130.25M24.65M11.57M-20.12M-53.05M
Investing Cash Flow-54.20M-113.12M-294.82M-19.60M29.14M86.63M
Financing Cash Flow-144.31M-52.39M13.95M235.08M14.95M134.06M

Inspire Medical Systems Technical Analysis

Technical Analysis Sentiment
Negative
Last Price92.30
Price Trends
50DMA
115.34
Negative
100DMA
131.16
Negative
200DMA
157.07
Negative
Market Momentum
MACD
-7.30
Negative
RSI
40.39
Neutral
STOCH
70.45
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For INSP, the sentiment is Negative. The current price of 92.3 is below the 20-day moving average (MA) of 93.12, below the 50-day MA of 115.34, and below the 200-day MA of 157.07, indicating a bearish trend. The MACD of -7.30 indicates Negative momentum. The RSI at 40.39 is Neutral, neither overbought nor oversold. The STOCH value of 70.45 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for INSP.

Inspire Medical Systems Risk Analysis

Inspire Medical Systems disclosed 59 risk factors in its most recent earnings report. Inspire Medical Systems reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Inspire Medical Systems Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
$3.93B59.5628.21%48.09%2410.18%
66
Neutral
$5.40B-91.13%22.37%31.14%
65
Neutral
$3.80B47.905.15%7.21%-23.29%
61
Neutral
$3.09B30.62-17.87%8.57%-1154.64%
58
Neutral
$2.71B53.158.07%22.05%785.52%
53
Neutral
$2.25B-26.40%55.71%24.37%
51
Neutral
$7.83B-0.18-40.10%2.29%21.46%-2.03%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
INSP
Inspire Medical Systems
92.30
-91.14
-49.68%
ITGR
Integer Holdings
108.07
-20.38
-15.87%
LIVN
LivaNova
56.49
6.25
12.44%
IRTC
Irhythm Technologies
169.79
97.37
134.45%
TMDX
TransMedics Group
117.38
-49.27
-29.56%
PRCT
PROCEPT BioRobotics
40.80
-37.89
-48.15%

Inspire Medical Systems Corporate Events

Executive/Board ChangesFinancial Disclosures
Inspire Medical Systems CFO to Step Down
Neutral
Aug 26, 2025

Inspire Medical Systems announced that its Chief Financial Officer, Richard J. Buchholz, will step down from his position effective December 31, 2025, to pursue other professional opportunities. Buchholz will remain in a financial advisory role until February 28, 2026, to ensure a smooth transition. The company has initiated a search for a new CFO and reaffirmed its 2025 financial guidance with expected revenues between $900 to $910 million. Buchholz has been instrumental in the company’s growth, contributing to its revenue increase from $4 million to over $800 million in 2024 and guiding it through its IPO and the challenges of the COVID-19 pandemic.

Stock BuybackBusiness Operations and Strategy
Inspire Medical Systems Announces $200M Share Buyback
Positive
Aug 11, 2025

On August 11, 2025, Inspire Medical Systems announced that its Board of Directors authorized a share repurchase program of up to $200 million. This decision reflects the company’s confidence in its growth prospects and the belief that its stock is undervalued. The repurchase program is part of a broader strategy to support the launch of Inspire V, their next-generation neurostimulation system, and to return capital to shareholders while continuing to invest in future growth.

Product-Related AnnouncementsExecutive/Board ChangesBusiness Operations and StrategyFinancial Disclosures
Inspire Medical Systems Reports Q2 2025 Financial Results
Neutral
Aug 4, 2025

Inspire Medical Systems announced its financial results for the second quarter of 2025, reporting a revenue of $217.1 million, an 11% increase from the previous year. Despite achieving a gross margin of 84%, the company faced an operating loss of $3.3 million, partly due to a $4.0 million non-cash impairment of a strategic investment. The company also launched its Inspire V neurostimulation system in the U.S., which has received positive feedback but is experiencing slower-than-expected commercial progress, impacting financial results for the year. Executive Vice President Randall A. Ban announced his retirement effective January 30, 2026, marking the end of his influential tenure at the company.

Product-Related Announcements
Inspire Medical Systems Launches Inspire V for OSA
Positive
Jun 13, 2025

Inspire Medical Systems announced the full launch of Inspire V in May 2025, highlighting its advanced accelerometer-based sensing technology for treating obstructive sleep apnea (OSA). This innovation simplifies the implant procedure and enhances therapy effectiveness by accurately timing stimulation during the most vulnerable phases of the breathing cycle, potentially improving patient outcomes and reducing the need for revisions.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 21, 2025