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Inspire Medical Systems (INSP)
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Inspire Medical Systems (INSP) AI Stock Analysis

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INSP

Inspire Medical Systems

(NYSE:INSP)

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Outperform 71 (OpenAI - 4o)
Rating:71Outperform
Price Target:
$94.00
▲(12.89% Upside)
Inspire Medical Systems shows strong financial performance and positive earnings call highlights, including revenue growth and improved margins. However, technical indicators suggest a bearish trend, and the stock's high P/E ratio indicates overvaluation. These factors combine to give the stock a moderate overall score.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong market demand and successful product adoption, which supports long-term business expansion.
Improved Gross Margin
Higher gross margins reflect efficient cost management and a favorable sales mix, enhancing profitability and financial resilience.
Reimbursement Improvements
Improved reimbursement rates expand patient access and affordability, potentially increasing the customer base and revenue.
Negative Factors
Increased Operating Expenses
Rising operating expenses can pressure margins and limit profitability, necessitating careful cost management to maintain financial health.
Decreased Net Income
Lower net income despite revenue growth suggests challenges in cost control or other operational inefficiencies impacting profitability.
Legal Fees Impact
Legal expenses can divert resources from growth initiatives and pose risks to financial stability if not resolved favorably.

Inspire Medical Systems (INSP) vs. SPDR S&P 500 ETF (SPY)

Inspire Medical Systems Business Overview & Revenue Model

Company DescriptionInspire Medical Systems, Inc. is a medical technology company focused on developing innovative solutions for patients suffering from obstructive sleep apnea (OSA). The company is primarily engaged in the design and commercialization of its flagship product, the Inspire therapy system, which is a surgically implanted device that stimulates the hypoglossal nerve to maintain an open airway during sleep. Inspire operates within the healthcare sector, targeting both patients and healthcare providers, aiming to enhance treatment options for sleep apnea beyond traditional CPAP devices.
How the Company Makes MoneyInspire Medical Systems generates revenue primarily through the sale of its Inspire therapy system, which includes the implantation device and related components. The company also earns income from the ongoing sale of accessories and follow-up care associated with the therapy. Revenue is driven by hospital and surgical center partnerships where the Inspire system is implemented, and the company often collaborates with healthcare professionals to promote and educate about the benefits of its therapy. Additionally, reimbursement from insurance providers plays a crucial role in the company's earnings, as it allows patients to afford the therapy, thereby expanding the potential customer base.

Inspire Medical Systems Earnings Call Summary

Earnings Call Date:Nov 03, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 10, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted strong revenue growth and improved gross margins, driven by the successful launch and adoption of Inspire V and positive clinical outcomes. However, these positives were somewhat offset by increased operating expenses and decreased net income compared to the prior year. The company remains optimistic with increased earnings guidance and improved reimbursement outlook.
Q3-2025 Updates
Positive Updates
Strong Revenue Growth
Third quarter revenue totaled $224.5 million, a 10% increase compared to the prior year period. U.S. revenue was $214.4 million, a 9% increase, and revenue outside the U.S. was $10.1 million, a 37% increase year-over-year.
Improved Gross Margin
Gross margin in the quarter was 85.8% compared to 84.1% in the prior year period, primarily due to increased sales volume and increased sales mix of Inspire V.
Positive Clinical Outcomes
The Singapore clinical study demonstrated significant performance improvement with a 20% reduction in surgical times. U.S. Limited-Market-Release showed a clinically relevant reduction in disease severity.
Increased Earnings Guidance
Earnings per share guidance increased to $0.90 to $1, up from $0.40 to $0.50 previously.
Reimbursement Improvements
CMS finalized the 2026 physician fee schedule at approximately $660, an 11% increase for CPT code 64568, effective January 1, 2026.
Negative Updates
Decreased Net Income
Net income for the quarter was $9.9 million compared to $18.5 million in the prior year period, representing diluted net income per share of $0.34 compared to $0.60 in the third quarter of 2024.
Increased Operating Expenses
Total operating expenses for the quarter were $183.1 million, an increase of 17% compared to the third quarter of 2024, primarily due to increased patient marketing expense and general corporate costs.
Legal Fees Impact
Operating expenses included $1.3 million in legal fees related to a civil investigative demand from the Department of Justice and patent infringement lawsuits with a competitor.
Company Guidance
During the Inspire Medical Systems' third-quarter 2025 earnings call, the company reiterated its full-year revenue guidance of $900 million to $910 million, representing a 12% to 13% growth from the previous year. The third-quarter revenue totaled $224.5 million, marking a 10% increase year-over-year, with U.S. revenue contributing $214.4 million. Operating income for the quarter was $9.6 million, and earnings per share were $0.34. The company increased its full-year earnings per share guidance to $0.90 to $1, up from a previous range of $0.40 to $0.50. Inspire also highlighted a gross margin of 85.8%, up from 84.1% in the prior year, driven by increased sales volume and a favorable sales mix of its Inspire V system. Looking ahead to 2026, the company provided an early indication of 10% to 11% revenue growth, citing strong performance and adoption of the Inspire V system.

Inspire Medical Systems Financial Statement Overview

Summary
Inspire Medical Systems exhibits strong financial health with consistent revenue growth, robust profit margins, and a solid balance sheet with low leverage. The company has improved its profitability and cash flow generation, although there is room for enhancing operational efficiency and cash flow conversion.
Income Statement
78
Positive
Inspire Medical Systems has shown consistent revenue growth, with a TTM revenue growth rate of 2.47%. The company has maintained strong gross profit margins above 84% over the years, indicating efficient cost management. The net profit margin has improved significantly from negative values in previous years to 6.17% in the TTM period, reflecting enhanced profitability. However, the EBIT and EBITDA margins, though positive, suggest room for improvement in operational efficiency.
Balance Sheet
82
Very Positive
The company's balance sheet is strong, with a low debt-to-equity ratio of 0.048, indicating minimal leverage and financial risk. Return on equity has improved to 7.87% in the TTM period, showcasing better utilization of shareholder funds. The equity ratio remains robust, reflecting a solid capital structure. Overall, the balance sheet indicates financial stability and prudent management of resources.
Cash Flow
75
Positive
Inspire Medical Systems has demonstrated positive free cash flow growth of 16.25% in the TTM period, indicating improved cash generation capabilities. The operating cash flow to net income ratio of 1.26 suggests healthy cash flow relative to earnings. However, the free cash flow to net income ratio of 0.72 indicates that not all earnings are translating into free cash flow, suggesting potential areas for cash flow optimization.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue882.62M802.80M624.80M407.86M233.39M115.38M
Gross Profit749.48M679.82M528.22M341.74M200.12M97.76M
EBITDA76.63M65.03M-17.06M-40.73M-38.62M-54.13M
Net Income44.56M53.51M-21.15M-44.88M-42.04M-57.20M
Balance Sheet
Total Assets807.72M808.38M676.81M564.88M295.08M281.19M
Cash, Cash Equivalents and Short-Term Investments322.59M445.55M460.38M451.41M214.47M234.36M
Total Debt32.58M31.79M24.85M8.87M34.09M30.63M
Total Liabilities141.26M118.69M104.30M68.87M66.04M51.44M
Stockholders Equity666.46M689.70M572.51M496.01M229.05M229.75M
Cash Flow
Free Cash Flow98.82M91.12M1.02M2.47M-24.79M-55.50M
Operating Cash Flow133.69M130.25M24.65M11.57M-20.12M-53.05M
Investing Cash Flow37.13M-113.12M-294.82M-19.60M29.14M86.63M
Financing Cash Flow-205.28M-52.39M13.95M235.08M14.95M134.06M

Inspire Medical Systems Technical Analysis

Technical Analysis Sentiment
Negative
Last Price83.27
Price Trends
50DMA
79.70
Positive
100DMA
93.11
Negative
200DMA
124.51
Negative
Market Momentum
MACD
1.47
Negative
RSI
51.51
Neutral
STOCH
23.63
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For INSP, the sentiment is Negative. The current price of 83.27 is above the 20-day moving average (MA) of 81.81, above the 50-day MA of 79.70, and below the 200-day MA of 124.51, indicating a neutral trend. The MACD of 1.47 indicates Negative momentum. The RSI at 51.51 is Neutral, neither overbought nor oversold. The STOCH value of 23.63 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for INSP.

Inspire Medical Systems Risk Analysis

Inspire Medical Systems disclosed 59 risk factors in its most recent earnings report. Inspire Medical Systems reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Inspire Medical Systems Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$4.56B53.9132.48%41.20%173.53%
71
Outperform
$2.42B57.226.54%16.81%34.90%
61
Neutral
$2.37B28.335.18%7.81%-26.32%
58
Neutral
$2.94B-17.63%8.97%-1024.86%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
41
Neutral
$1.56B-18.13-27.22%50.07%21.22%
40
Underperform
$5.39B-53.15%25.45%66.62%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
INSP
Inspire Medical Systems
83.27
-105.46
-55.88%
ITGR
Integer Holdings
68.13
-69.98
-50.67%
LIVN
LivaNova
53.42
2.10
4.09%
IRTC
Irhythm Technologies
169.70
95.71
129.36%
TMDX
TransMedics Group
123.82
47.78
62.84%
PRCT
PROCEPT BioRobotics
27.89
-65.71
-70.20%

Inspire Medical Systems Corporate Events

Inspire Medical’s Earnings Call: Growth Amid Rising Costs
Nov 5, 2025

Inspire Medical’s recent earnings call painted a picture of robust growth tempered by rising costs. The company reported strong revenue growth and improved gross margins, largely driven by the successful launch and adoption of Inspire V and positive clinical outcomes. However, these positives were somewhat offset by increased operating expenses and decreased net income compared to the prior year. Despite these challenges, the company remains optimistic, with increased earnings guidance and an improved reimbursement outlook.

Inspire Medical Systems Reports Strong Q3 2025 Growth
Nov 4, 2025

Inspire Medical Systems, Inc. is a medical technology company specializing in minimally invasive solutions for obstructive sleep apnea, offering the first FDA-approved neurostimulation therapy of its kind. In the third quarter of 2025, Inspire Medical reported a revenue of $224.5 million, marking a 10% increase from the previous year. The company’s gross margin improved to 85.8%, and it achieved a net income of $9.9 million, with an adjusted net income of $11.2 million. Inspire Medical also completed a $50 million share repurchase and presented positive clinical data for its Inspire V system.

Stock BuybackFinancial Disclosures
Inspire Medical Systems Reports Q3 2025 Financial Results
Positive
Nov 3, 2025

Inspire Medical Systems reported its financial results for the third quarter of 2025, showing a 10% increase in revenue to $224.5 million compared to the previous year. The company achieved a gross margin of 85.8% and a net income of $9.9 million. The Inspire V system, which offers enhanced performance and reduced surgical procedure time, has received positive feedback from clinicians, with over 75% of centers ready to transition to this new system. Inspire reaffirmed its full-year revenue guidance of $900 to $910 million and increased its diluted net income per share guidance to $0.90 to $1.00. The company completed a $50 million share repurchase and presented clinical evidence of the Inspire V system’s efficacy at industry meetings.

The most recent analyst rating on (INSP) stock is a Hold with a $77.00 price target. To see the full list of analyst forecasts on Inspire Medical Systems stock, see the INSP Stock Forecast page.

Inspire Medical’s EURO-STIM Registry: A Long-Term Look at Sleep Apnea Treatment
Oct 27, 2025

Study Overview: The EURO-STIM Registry, officially titled ‘Longitudinal Outcomes and Adherence of the Inspire System, EURO-STIM Registry,’ aims to measure the long-term outcomes and adherence of the Inspire System in patients with Obstructive Sleep Apnea (OSA). This study is significant as it seeks to capture the life cycle of the patient’s use of the Inspire System through routine clinical care visits, providing valuable insights into its effectiveness and patient adherence over time.

Inspire Medical’s New Study: Expanding Horizons for OSA Treatment
Oct 27, 2025

Inspire Medical Systems, Inc. is conducting a significant clinical study titled ‘Inspire UAS High AHI/High BMI Post-Approval Study.’ The study aims to evaluate the long-term safety and effectiveness of the Inspire® UAS System in patients with obstructive sleep apnea (OSA) who have a higher Apnea Hypopnea Index (AHI) and Body Mass Index (BMI). This research is crucial as it expands the patient population for this treatment, potentially offering new hope for those with severe OSA conditions.

Inspire Medical’s Pediatric Study: A Closer Look at the OSA Treatment Registry
Oct 27, 2025

Study Overview: The Inspire Pediatric Post-Approval Registry aims to evaluate the long-term safety and effectiveness of the Inspire Upper Airway Stimulation (UAS) System in pediatric patients aged 18-21 years with moderate to severe obstructive sleep apnea (OSA). This multi-center, single-arm study is significant as it seeks to provide critical data on the system’s performance over a five-year period post-implant.

Inspire Medical’s New Study on Sleep Apnea in Down Syndrome Patients: A Market Game Changer?
Oct 27, 2025

Inspire Medical Systems, Inc. has launched the Pediatric Down Syndrome Post-Approval Study to evaluate the safety and effectiveness of the Inspire therapy in adolescents and young adults with Down syndrome and severe sleep apnea. This study aims to provide ongoing assessments of the Inspire UAS System in this specific population, highlighting its significance in improving patient outcomes.

Business Operations and StrategyProduct-Related Announcements
Inspire Medical Systems Unveils Positive Data for Inspire V
Positive
Oct 10, 2025

In October 2025, Inspire Medical Systems published clinical outcomes data for their Inspire V system at the ISSS/AAO-HNS meetings in Indianapolis. The data, from a Singapore study and a limited U.S. market release, showed significant improvements in patient adherence, safety, and surgical efficiency compared to previous models. The Inspire V system demonstrated a 20% reduction in surgical times and superior respiratory sensing, leading to enhanced patient comfort and therapy outcomes. The results indicate a promising advancement in treating obstructive sleep apnea, with implications for increased adoption and potential changes in reimbursement levels.

The most recent analyst rating on (INSP) stock is a Buy with a $125.00 price target. To see the full list of analyst forecasts on Inspire Medical Systems stock, see the INSP Stock Forecast page.

Executive/Board ChangesFinancial Disclosures
Inspire Medical Systems CFO to Step Down
Neutral
Aug 26, 2025

Inspire Medical Systems announced that its Chief Financial Officer, Richard J. Buchholz, will step down from his position effective December 31, 2025, to pursue other professional opportunities. Buchholz will remain in a financial advisory role until February 28, 2026, to ensure a smooth transition. The company has initiated a search for a new CFO and reaffirmed its 2025 financial guidance with expected revenues between $900 to $910 million. Buchholz has been instrumental in the company’s growth, contributing to its revenue increase from $4 million to over $800 million in 2024 and guiding it through its IPO and the challenges of the COVID-19 pandemic.

The most recent analyst rating on (INSP) stock is a Hold with a $97.00 price target. To see the full list of analyst forecasts on Inspire Medical Systems stock, see the INSP Stock Forecast page.

Business Operations and StrategyStock Buyback
Inspire Medical Systems Announces $200M Share Buyback
Positive
Aug 11, 2025

On August 11, 2025, Inspire Medical Systems announced that its Board of Directors authorized a share repurchase program of up to $200 million. This decision reflects the company’s confidence in its growth prospects and the belief that its stock is undervalued. The repurchase program is part of a broader strategy to support the launch of Inspire V, their next-generation neurostimulation system, and to return capital to shareholders while continuing to invest in future growth.

The most recent analyst rating on (INSP) stock is a Hold with a $200.00 price target. To see the full list of analyst forecasts on Inspire Medical Systems stock, see the INSP Stock Forecast page.

Inspire Medical’s Mixed Earnings Call: Growth Amid Challenges
Aug 6, 2025

The recent earnings call for Inspire Medical Systems presented a mixed sentiment, highlighting significant revenue growth and promising advancements in the Inspire V system. However, these positive developments were somewhat overshadowed by challenges in executing the transition to the new system and a reduction in financial guidance.

Inspire Medical Systems Reports Q2 2025 Financials
Aug 5, 2025

Inspire Medical Systems, Inc. is a medical technology company that specializes in developing and commercializing innovative, minimally invasive solutions for patients with obstructive sleep apnea. The company’s proprietary Inspire therapy is the first FDA-approved neurostimulation technology for treating moderate to severe obstructive sleep apnea.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 05, 2025