Revenue Growth
Fourth quarter revenue increased 12% to $269 million; full year 2025 revenue increased 14% to $912 million, driven by growth at existing centers and new center additions.
Profitability and Earnings Performance
Fourth quarter delivered positive operating income and earnings. Q4 net income per diluted share rose by $3.51 to $4.66 and full year net income per diluted share rose by $3.09 to $4.89.
Adjusted Earnings and Cash Flow
Q4 adjusted net income per diluted share increased $0.51 to $1.65 and full year adjusted EPS increased $0.80 to $2.42. Fourth quarter operating cash flow was $52 million, bringing full year operating cash flow to $117 million.
Capital Allocation and Balance Sheet Strength
Completed $50 million of share repurchases in Q4 and $175 million for the full year; ended the quarter with $405 million in cash and investments, supporting investments for growth.
Inspire 5 Clinical and Reliability Performance
Inspire 5 showed clinical superiority vs. Inspire 4: reduced surgical time, significantly improved inspiratory overlap, and a 79.5% responder rate (Sher criteria) in the Singapore study vs. 66% in STAR pivotal trial. System reliability improved in 2025 with device explants at 0.5% and revisions at 1.5%.
Successful U.S. Launch Execution
Physician training complete, contracting over 95% complete for centers, SleepSync onboarding complete for over 90% of centers, and over 90% of centers implanting Inspire 5; expect stable product inventory for Inspire 5 through 2026.
Product and R&D Progress
Received FDA approval for 3 Tesla MRI compatibility; testing prior-authorization feature in SleepSync; announced Inspire 6 program for sleep detection and auto-activation targeting improved adherence.
Operational Discipline
Q4 and full year operating margins improved driven by sales leverage and a higher sales mix of Inspire 5 systems; management cites disciplined spending and targeted commercial reorganization (295 U.S. territories, 275 field clinical reps).
2026 Financial Guidance (Range Provided)
Management provided a full-year 2026 revenue outlook of $950 million to $1,000 million (4% to 10% growth), adjusted operating margin guidance of 6% to 8%, and adjusted EPS guidance of $1.85 to $2.35, while disclosing assumptions and risks.
Commercial and Global Footprint
U.S. remains the core market (Q4 U.S. revenue $256.9M, ~95% of revenue); management continues focus on expanding provider capacity, training advanced practice providers, and certifying additional surgeons to treat more patients.