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BillionToOne, Inc. Class A (BLLN)
NASDAQ:BLLN
US Market

BillionToOne, Inc. Class A (BLLN) AI Stock Analysis

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BLLN

BillionToOne, Inc. Class A

(NASDAQ:BLLN)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$87.00
▼(-16.87% Downside)
The score is held down primarily by weak financial performance (ongoing losses and cash burn) and soft technical momentum. These are partially offset by a very strong earnings-call outlook with rapid growth, major margin expansion, and guidance pointing to sustained GAAP operating profitability; valuation remains challenged due to negative earnings and no dividend.
Positive Factors
Rapid revenue and test-volume growth
Sustained high revenue and test-volume growth demonstrates strong commercial traction and accelerating market adoption of the platform. Continued double‑digit organic demand provides a durable revenue runway and supports scaling investments in sales, EMR integration, and oncology expansion over the next 2–6 months.
Material gross margin improvement
Substantial margin expansion reflects improved unit economics via higher ASPs and lower cost per test. Higher sustainable gross margins enhance the company's ability to convert revenue into operating profitability and finance growth, reducing dependence on external capital as volumes scale.
Stronger capital structure post-IPO
A successful IPO and markedly improved leverage materially increase financial flexibility to fund commercialization, EMR integration, and R&D. Lower debt burden and larger equity base reduce refinancing risk and better position the company to execute its multi-year growth plan without near-term liquidity strain.
Negative Factors
Ongoing negative operating and free cash flow
Persistent cash burn, even if reduced, is a structural pressure that requires sustained operating improvement or fresh capital. Negative cash flow limits strategic optionality, increases dependence on financing for growth initiatives, and elevates execution risk if revenue/margin progress stalls.
Continued net losses despite improvement
While losses have narrowed, ongoing negative net income indicates the company has not fully converted operational improvements into sustained profitability. Until consistent multi-quarter net profits and positive free cash flow are achieved, equity holders face execution and capital‑raise dilution risks.
Reimbursement, coverage, and EMR integration risks
Structural payor coverage uncertainty and required EMR investments can slow adoption, especially for oncology tests that need payer mix expansion. These are durable operational risks that can constrain revenue realization and margin sustainability until coverage and health‑system integrations are secured.

BillionToOne, Inc. Class A (BLLN) vs. SPDR S&P 500 ETF (SPY)

BillionToOne, Inc. Class A Business Overview & Revenue Model

Company Description
How the Company Makes Money

BillionToOne, Inc. Class A Financial Statement Overview

Summary
Income Statement
38
Negative
Balance Sheet
62
Positive
Cash Flow
34
Negative
BreakdownDec 2024Dec 2023
Income Statement
Total Revenue152.58M71.73M
Gross Profit80.92M17.31M
EBITDA-27.47M-72.94M
Net Income-41.57M-82.68M
Balance Sheet
Total Assets302.06M191.68M
Cash, Cash Equivalents and Short-Term Investments191.48M97.27M
Total Debt109.38M146.35M
Total Liabilities134.31M161.20M
Stockholders Equity167.75M30.47M
Cash Flow
Free Cash Flow-46.78M-59.85M
Operating Cash Flow-41.38M-53.67M
Investing Cash Flow-5.43M82.84M
Financing Cash Flow141.02M13.40M

BillionToOne, Inc. Class A Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
73
Outperform
$33.09B-105.22-29.02%38.17%-28.77%
70
Outperform
$4.08B-8.39-16.83%20.53%82.91%
58
Neutral
$14.05B-34.8530.38%24.17%
53
Neutral
$864.62M-20.44-3.80%13.60%74.64%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$4.32B-297.49
41
Neutral
$569.54M-72.52%0.21%-233.51%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BLLN
BillionToOne, Inc. Class A
MYGN
Myriad Genetics
6.04
-6.35
-51.25%
NTRA
Natera
240.34
81.98
51.77%
FLGT
Fulgent Genetics
28.65
11.55
67.54%
GH
Guardant Health
111.98
75.32
205.46%
GRAL
GRAIL Inc
97.44
80.02
459.36%

BillionToOne, Inc. Class A Corporate Events

Business Operations and StrategyFinancial Disclosures
BillionToOne Issues Strong 2026 Growth and Profit Outlook
Positive
Jan 12, 2026

On January 12, 2026, BillionToOne, Inc. announced financial guidance indicating it expects to maintain previously reiterated full-year 2025 revenue in the range of $293 million to $299 million with positive GAAP operating income, and projected that full-year 2026 revenue will rise to between $415 million and $430 million, implying 40% to 45% growth versus the midpoint of its 2025 outlook while remaining GAAP operating income positive. The company framed this guidance as evidence of its ability to scale its differentiated molecular diagnostics platform and deepen its role in addressing significant clinical needs, signaling continued operational momentum and a strengthening growth profile for investors and other stakeholders as it advances its technology and commercial footprint.

The most recent analyst rating on (BLLN) stock is a Hold with a $94.00 price target. To see the full list of analyst forecasts on BillionToOne, Inc. Class A stock, see the BLLN Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
BillionToOne Appoints Anthony Pagano as Audit Chair
Positive
Dec 9, 2025

On December 8, 2025, BillionToOne’s board of directors expanded by appointing Anthony Pagano as a Class III director and chairperson of the Audit Committee, effective January 1, 2026. This strategic move is expected to strengthen the company’s governance as it continues its growth trajectory. In its third quarter of 2025, BillionToOne reported a significant financial performance with a 117% increase in total revenue compared to the previous year, driven by substantial growth in prenatal and oncology testing revenues. The company also achieved a positive operating income and cash flow, marking a turnaround from the previous year’s losses. BillionToOne’s successful IPO and strong financial results underscore its commitment to innovation and market expansion.

The most recent analyst rating on (BLLN) stock is a Hold with a $117.00 price target. To see the full list of analyst forecasts on BillionToOne, Inc. Class A stock, see the BLLN Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
BillionToOne, Inc. Completes Successful IPO Raising $314 Million
Positive
Nov 10, 2025

On November 7, 2025, BillionToOne, Inc. completed its initial public offering (IPO) of 5,233,765 shares of Class A common stock at a price of $60.00 per share, raising approximately $314.0 million in gross proceeds. This significant financial milestone, marked by the filing of amended and restated corporate documents, positions the company for future growth and impacts its market presence by enhancing its capital structure.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 12, 2026