Revenue Growth and Profitability
Total revenue of $108.4M in Q1 2026, up 84% year-over-year; operating income $17.8M; GAAP operating margin 16%; adjusted EBITDA margin 24%; net income $18.0M ($0.34 per diluted share) vs a net loss in Q1 2025.
Test Volume and ASP Expansion
Approximately 188,000 tests in Q1, up 44% YoY; average selling price (ASP) $571 per test, up 28% YoY and +$10 sequentially; gross margin expanded to 73% (up 9 percentage points YoY); overall COGS per test $153 (down 5% sequentially, +1% YoY).
Prenatal Business Strength
Prenatal revenue $97.7M in Q1, up 72% YoY; prenatal volumes +10% quarter-over-quarter; prenatal segment remains high-margin and a primary driver of overall gross margin expansion.
Rapid Oncology Ramp
Oncology revenue grew nearly 5x to $10.7M in Q1 (≈+400% YoY) with an annualized run rate of ~$43M; oncology volumes +25% quarter-over-quarter; ~60% of NorthStar Select orders opt into CH, indicating strong clinical adoption.
Stronger Market Access / Payer Contracts
In-network contract secured with Anthem, bringing total contracted lives to ~300 million in the U.S. (over 90% of patients); UnitedHealthcare in-network effective April 1; management expects these contracts to lift ASPs over time.
Product Innovation and Pipeline Progress
Launched Unity Confirm (first noninvasive fetal cell–based confirmation assay) with initial results showing 100% concordance to invasive diagnostics; launched oncology PGx and CH; tumor-naive MRD launch on track for year-end; responded to MolDX comments for Response coverage.
Raised 2026 Guidance
2026 revenue guidance raised to $445M–$465M (a $20M increase at both ends), implying 48%–52% growth versus 2025, reflecting Q1 strength and expected ASP improvements from payer contracts.
Strong Balance Sheet and Cash Generation
Ended Q1 with ~$537M cash and equivalents; cash flow from operations minus capex of $11.0M in Q1; management emphasizes continued profitability while investing in growth.