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Aldeyra Therapeutics (ALDX)
NASDAQ:ALDX
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Aldeyra Therapeutics (ALDX) AI Stock Analysis

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ALDX

Aldeyra Therapeutics

(NASDAQ:ALDX)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
$1.50
▼(-16.67% Downside)
Action:ReiteratedDate:05/02/26
The score is pressured primarily by weak financial performance (no revenue, ongoing losses, and negative cash flow with a recent deterioration) and bearish technicals (price below key moving averages with negative MACD). Corporate events are mixed but dominated by the FDA rejection, while valuation is constrained by the negative P/E and lack of dividend support.
Positive Factors
Platform breadth (RASP-modulation)
A mechanism-focused RASP platform across ophthalmic, dermatologic, metabolic, hepatic and CNS indications provides multiple development pathways and 'shots on goal.' This diversifies long-term commercial opportunity beyond a single asset and supports durable value creation if any program advances to approval.
Negative Factors
Regulatory setback: second FDA CRL
A second FDA Complete Response Letter materially increases approval uncertainty and could require new studies or narrower indications. This raises expected development costs, delays commercialization timelines and diminishes the near-to-medium term probability of product-driven revenues, affecting strategic options.
Read all positive and negative factors
Positive Factors
Negative Factors
Platform breadth (RASP-modulation)
A mechanism-focused RASP platform across ophthalmic, dermatologic, metabolic, hepatic and CNS indications provides multiple development pathways and 'shots on goal.' This diversifies long-term commercial opportunity beyond a single asset and supports durable value creation if any program advances to approval.
Read all positive factors

Aldeyra Therapeutics (ALDX) vs. SPDR S&P 500 ETF (SPY)

Aldeyra Therapeutics Business Overview & Revenue Model

Company Description
Aldeyra Therapeutics, Inc., a biotechnology company, develops and commercializes medicines for immune-mediated ocular and systemic diseases. The company's lead product candidate is reproxalap, a reactive aldehyde species (RASP)modulator, which is ...
How the Company Makes Money
Aldeyra is not known to have a commercialized product generating recurring product sales; as a clinical-stage biotech, it primarily funds operations through capital raising (e.g., public equity offerings) and other financing activities rather than...

Aldeyra Therapeutics Financial Statement Overview

Summary
Financial profile remains weak: no revenue, persistent net losses, and consistently negative operating/free cash flow. While leverage has been relatively moderate, the most recent period shows a sharp deterioration in operating results and a large step-up in cash outflows, increasing funding/dilution risk.
Income Statement
12
Very Negative
Balance Sheet
48
Neutral
Cash Flow
22
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit0.000.000.000.000.00
EBITDA-31.69M-53.68M-35.21M-60.07M-55.77M
Net Income-33.85M-55.85M-37.54M-62.02M-57.78M
Balance Sheet
Total Assets72.06M104.61M148.33M181.29M233.14M
Cash, Cash Equivalents and Short-Term Investments70.04M101.15M142.82M174.30M229.79M
Total Debt15.53M15.30M15.66M16.08M15.86M
Total Liabilities27.81M33.60M28.53M30.28M27.40M
Stockholders Equity44.25M71.00M119.80M151.01M205.74M
Cash Flow
Free Cash Flow-33.35T-43.21M-30.33M-56.65M-42.56M
Operating Cash Flow-33.35T-43.21M-30.33M-56.64M-42.56M
Investing Cash Flow47.74T-44.92M30.00M-29.95M-7.81K
Financing Cash Flow1.12T-171.42K-1.27M1.22M194.50M

Aldeyra Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.80
Price Trends
50DMA
3.55
Negative
100DMA
4.24
Negative
200DMA
4.73
Negative
Market Momentum
MACD
-0.47
Negative
RSI
35.25
Neutral
STOCH
80.49
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ALDX, the sentiment is Negative. The current price of 1.8 is above the 20-day moving average (MA) of 1.75, below the 50-day MA of 3.55, and below the 200-day MA of 4.73, indicating a neutral trend. The MACD of -0.47 indicates Negative momentum. The RSI at 35.25 is Neutral, neither overbought nor oversold. The STOCH value of 80.49 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ALDX.

Aldeyra Therapeutics Risk Analysis

Aldeyra Therapeutics disclosed 89 risk factors in its most recent earnings report. Aldeyra Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aldeyra Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$1.08B3.161.71%90.50%
52
Neutral
$473.91M-7.84-51.44%60.69%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$279.41M-4.5888.31%36.75%27.97%
44
Neutral
$95.91M-9.19-63.75%39.96%
44
Neutral
$445.76M-1.23-146.42%4.95%
43
Neutral
$149.43M-8.6225.65%35.99%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ALDX
Aldeyra Therapeutics
1.59
-1.11
-41.11%
OMER
Omeros
15.06
8.25
121.15%
GALT
Galectin Therapeutics
2.27
0.96
73.28%
FHTX
Foghorn Therapeutics
4.76
0.88
22.68%
CADL
Candel Therapeutics
6.47
1.49
29.92%
NMRA
Neumora Therapeutics, Inc.
2.44
1.74
248.57%

Aldeyra Therapeutics Corporate Events

Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
Aldeyra Updates Reproxalap Outlook and Extends Cash Runway
Positive
May 1, 2026
On May 1, 2026, Aldeyra Therapeutics released an updated corporate overview detailing standardized treatment estimates and confidence intervals for the primary endpoints of all proposed commercial dosing regimen efficacy trials of reproxalap in dr...
Executive/Board Changes
Aldeyra Therapeutics Announces Upcoming Board Member Departure
Neutral
Apr 20, 2026
On April 20, 2026, Aldeyra Therapeutics, Inc. announced that Board member Martin J. Joyce has decided not to stand for re-election at the company’s 2026 annual meeting of stockholders and will continue to serve until his term expires at that...
Business Operations and StrategyFinancial Disclosures
Aldeyra Repays Hercules Loan, Boosting Financial Flexibility
Positive
Apr 1, 2026
Aldeyra Therapeutics, Inc. previously entered into a Loan and Security Agreement in March 2019 with Hercules Capital, Inc. and a syndicate of lenders, known as the Hercules Credit Facility, which had a scheduled maturity date of April 1, 2026. On ...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
FDA Issues Second Complete Response Letter for Reproxalap
Negative
Mar 17, 2026
On March 17, 2026, Aldeyra Therapeutics announced that the U.S. Food and Drug Administration issued a Complete Response Letter rejecting the New Drug Application for reproxalap in dry eye disease, citing a lack of substantial evidence of efficacy,...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 02, 2026