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Galectin Therapeutics Inc (GALT)
NASDAQ:GALT

Galectin Therapeutics (GALT) AI Stock Analysis

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GALT

Galectin Therapeutics

(NASDAQ:GALT)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
$4.00
▼(-29.95% Downside)
The score is held down primarily by very weak financial performance (no meaningful revenue, heavy losses, negative equity, and continued cash burn with rising debt). Technicals also reflect a soft trend with negative momentum signals. Offsetting these, recent clinical/regulatory progress and insider financing support are positives but not enough to overcome the current financial risk profile.
Positive Factors
Clinical Trial Progress
Positive clinical trial results for Belapectin indicate potential for future product approval and commercialization, enhancing long-term growth prospects.
Partnership Opportunities
Potential partnerships can provide strategic resources and financial support, crucial for advancing R&D and reducing financial strain.
Innovative Drug Development
Targeting galectin proteins positions the company at the forefront of innovative treatments for fibrosis and cancer, offering a competitive edge in the biotech industry.
Negative Factors
Financial Instability
High leverage and negative equity indicate financial instability, which could hinder long-term operational sustainability and growth.
Zero Revenue Production
Lack of revenue generation underscores the risk of prolonged reliance on external funding, affecting financial health and investment attractiveness.
Increasing Financial Losses
Rising losses reflect increasing operational costs without revenue, posing a challenge to achieving profitability and financial stability.

Galectin Therapeutics (GALT) vs. SPDR S&P 500 ETF (SPY)

Galectin Therapeutics Business Overview & Revenue Model

Company DescriptionGalectin Therapeutics Inc. is a biotechnology company focused on developing innovative therapies to improve the lives of patients with chronic liver diseases and cancer. The company operates in the biotechnology and pharmaceutical sectors, with a core emphasis on discovering and developing drugs targeting galectin proteins, which are critical in numerous disease processes. Galectin Therapeutics aims to leverage its proprietary technology to create novel treatments, primarily targeting fibrosis and cancer.
How the Company Makes MoneyGalectin Therapeutics primarily makes money through research and development collaborations, licensing agreements, and milestone payments related to its drug candidates. The company partners with larger pharmaceutical firms to advance the development and commercialization of its therapies, receiving payments for achieving specific research and development milestones. Additionally, Galectin Therapeutics may earn revenue through licensing its proprietary technology and intellectual property to other companies, which can include upfront payments, royalties, and other financial incentives contingent upon the successful commercialization of their drug candidates.

Galectin Therapeutics Financial Statement Overview

Summary
Galectin Therapeutics exhibits the financial profile of an early-stage biotechnology company with no revenue production and increasing financial losses. The balance sheet is strained, marked by high debt and negative equity, suggesting potential financial risk. Cash flow trends demonstrate reliance on external financing to sustain operations, typical for firms focused on R&D in the biotech sector. This financial position underscores the importance of successful future product development and commercialization.
Income Statement
Galectin Therapeutics has consistently reported zero revenue over the last several years, indicating a lack of commercialized products. The net income has been negative, with losses growing from $13.38 million in 2019 to $47.05 million in 2024. This trend reflects increasing operating costs without offsetting revenue, a common challenge for biotechnology firms in the R&D phase.
Balance Sheet
The company has negative stockholders' equity, which worsened from $45.60 million positive in 2019 to $103.07 million negative in 2024, indicating high leverage and financial instability. The total debt has increased significantly, while assets remain low, reflecting potential liquidity issues and reliance on debt financing.
Cash Flow
Operating cash flow has been negative, indicating cash burn typical for pre-revenue biotech firms. However, the company has managed to secure financing cash flow intermittently, indicating some success in raising funds to support operations. Despite this, free cash flow remains negative, highlighting ongoing financial challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-22.00K-37.00K-33.00K-32.00K-41.00K-36.00K
EBITDA-30.17M-41.47M-38.24M-37.71M-30.00M-23.34M
Net Income-37.30M-47.05M-41.07M-38.78M-30.53M-23.46M
Balance Sheet
Total Assets12.87M17.50M28.20M21.29M41.83M29.60M
Cash, Cash Equivalents and Short-Term Investments11.53M15.12M25.66M18.59M39.65M27.14M
Total Debt122.31M106.25M71.81M39.87M29.06M44.00K
Total Liabilities138.17M120.56M88.44M53.48M39.21M5.41M
Stockholders Equity-125.30M-103.07M-60.24M-32.19M2.62M24.19M
Cash Flow
Free Cash Flow-30.62M-41.77M-32.97M-31.06M-24.31M-20.60M
Operating Cash Flow-30.62M-41.77M-32.97M-31.06M-24.31M-20.60M
Investing Cash Flow0.000.000.000.000.000.00
Financing Cash Flow15.09M31.23M40.03M10.00M36.81M263.00K

Galectin Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.71
Price Trends
50DMA
5.26
Negative
100DMA
4.94
Negative
200DMA
3.48
Negative
Market Momentum
MACD
-0.57
Positive
RSI
28.25
Positive
STOCH
10.80
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GALT, the sentiment is Negative. The current price of 5.71 is above the 20-day moving average (MA) of 4.69, above the 50-day MA of 5.26, and above the 200-day MA of 3.48, indicating a bearish trend. The MACD of -0.57 indicates Positive momentum. The RSI at 28.25 is Positive, neither overbought nor oversold. The STOCH value of 10.80 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GALT.

Galectin Therapeutics Risk Analysis

Galectin Therapeutics disclosed 38 risk factors in its most recent earnings report. Galectin Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Galectin Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$401.65M-5.57-32.21%60.40%
55
Neutral
$609.56M-1.17-50.23%14.68%89.16%
52
Neutral
$953.61M-6.6712.32%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$225.74M-1.87-46.09%-80.88%-388.61%
44
Neutral
$206.33M-5.4118.82%
44
Neutral
$167.14M-0.98-96.44%46.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GALT
Galectin Therapeutics
3.20
2.09
188.29%
OMER
Omeros
13.45
4.66
53.01%
VYGR
Voyager Therapeutics
4.06
-1.22
-23.11%
TECX
Tectonic Therapeutic
21.46
-16.37
-43.27%
JBIO
Jade Biosciences
13.25
4.11
44.97%
TNYA
Tenaya Therapeutics
0.77
-0.73
-48.53%

Galectin Therapeutics Corporate Events

Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Galectin Advances Belapectin Program, Secures New Insider Financing
Positive
Dec 19, 2025

On December 19, 2025, Galectin Therapeutics reported that the U.S. Food and Drug Administration provided a written response to the company’s Type C meeting request on the development program for belapectin, leading the company to believe there is regulatory alignment on the proposed patient population for a future registration trial in MASH cirrhosis. The company plans a follow-up Type C meeting to finalize remaining trial design details and to present new biomarker data, viewing this interaction as a key step toward a pivotal Phase 3 study and an opportunity to integrate input from external key opinion leaders, which it sees as important for advancing belapectin’s clinical strategy. Separately on December 19, 2025, Galectin Therapeutics entered into a new unsecured, convertible line of credit of up to $10 million with its chairman, Richard E. Uihlein, and extended the maturity of all his existing convertible credit lines and notes to June 30, 2027, a move that, together with existing cash, is expected to fund operations through at least March 2027 and underscores continued insider financial support as the company progresses its late-stage liver disease program.

The most recent analyst rating on (GALT) stock is a Buy with a $11.00 price target. To see the full list of analyst forecasts on Galectin Therapeutics stock, see the GALT Stock Forecast page.

Shareholder Meetings
Galectin Therapeutics Holds 2025 Annual Stockholders Meeting
Neutral
Dec 8, 2025

At the 2025 Annual Meeting of Stockholders on December 3, 2025, Galectin Therapeutics‘ stockholders elected the nominated directors and approved a non-binding advisory resolution on executive compensation. They also ratified Cherry Bekaert LLP as the independent registered public accounting firm for the year ending December 31, 2025. The board decided to conduct advisory votes on executive compensation every three years.

The most recent analyst rating on (GALT) stock is a Buy with a $6.00 price target. To see the full list of analyst forecasts on Galectin Therapeutics stock, see the GALT Stock Forecast page.

Business Operations and StrategyShareholder Meetings
Galectin Therapeutics Reveals Promising NAVIGATE Trial Results
Positive
Dec 3, 2025

On December 3, 2025, Galectin Therapeutics presented compelling results from its NAVIGATE trial at its Annual Meeting of Stockholders. The trial focused on belapectin’s efficacy in treating MASH cirrhosis and portal hypertension, showing significant benefits in reducing liver stiffness and varices compared to placebo. The company highlighted the trial’s adaptive design and the decision to unblind data in 2024, which led to extensive data analysis throughout 2025. Key findings included belapectin’s impact on fibrosis and inflammation markers, with no drug-related serious adverse events reported. The results reinforce belapectin’s potential to change the treatment landscape for patients with no FDA-approved therapy, and Galectin is anticipating FDA feedback and exploring strategic opportunities to maximize program value.

The most recent analyst rating on (GALT) stock is a Buy with a $6.00 price target. To see the full list of analyst forecasts on Galectin Therapeutics stock, see the GALT Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Galectin Therapeutics Presents Promising NAVIGATE Trial Results
Positive
Nov 10, 2025

On November 10, 2025, Galectin Therapeutics announced the presentation of its NAVIGATE trial results at the AASLD 2025 Annual Meeting. The Phase 2b trial evaluated belapectin, a galectin-3 inhibitor, in patients with compensated MASH cirrhosis and portal hypertension. The results demonstrated belapectin’s potential as a disease-modifying therapy, showing significant antifibrotic effects and a reduction in the incidence of new varices compared to placebo. These findings suggest a promising therapeutic option for patients with limited treatment choices, and the company is focused on advancing regulatory discussions and strategic partnerships to further develop belapectin.

The most recent analyst rating on (GALT) stock is a Buy with a $6.00 price target. To see the full list of analyst forecasts on Galectin Therapeutics stock, see the GALT Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025