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Tenaya Therapeutics (TNYA)
NASDAQ:TNYA
US Market
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Tenaya Therapeutics (TNYA) AI Stock Analysis

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TNYA

Tenaya Therapeutics

(NASDAQ:TNYA)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$0.70
▼(-47.07% Downside)
Action:Reiterated
Date:05/30/26
The score is primarily weighed down by weak financial performance (minimal revenue, large losses, and persistent cash burn). Technicals are neutral with weak near-term momentum, and valuation is limited by negative earnings and no dividend. Corporate events provide some offset via the Alnylam collaboration, but potential dilution from the expanded equity plan adds risk.
Positive Factors
Partnership funding
A collaboration that includes upfront payment plus structured milestone upside materially improves the company's multi-quarter funding outlook and de-risks program financing. Milestone-stepped payments provide contingent, non-product revenue that can sustain R&D and reduce urgent reliance on equity markets over time.
Negative Factors
Heavy cash burn
Sustained negative operating and free cash flow at this magnitude implies ongoing dependence on external financing or milestone payments. Continued burn without material revenue growth heightens dilution risk and could constrain the pace or scope of clinical programs if anticipated partner payments or financings are delayed.
Read all positive and negative factors
Positive Factors
Negative Factors
Partnership funding
A collaboration that includes upfront payment plus structured milestone upside materially improves the company's multi-quarter funding outlook and de-risks program financing. Milestone-stepped payments provide contingent, non-product revenue that can sustain R&D and reduce urgent reliance on equity markets over time.
Read all positive factors

Tenaya Therapeutics (TNYA) vs. SPDR S&P 500 ETF (SPY)

Tenaya Therapeutics Business Overview & Revenue Model

Company Description
Tenaya Therapeutics, Inc. is a U.S.-based biotechnology firm focused on unearthing, advancing, and providing novel treatments for various cardiovascular diseases. The company harnesses advanced scientific platforms, including cellular regeneration...
How the Company Makes Money
Tenaya Therapeutics is a clinical-stage biotechnology company; specific, consistent product-based commercial revenue is not publicly available in the provided context, and the company has historically operated primarily by funding R&D through exte...

Tenaya Therapeutics Financial Statement Overview

Summary
Financials reflect an early-stage biotech profile: minimal TTM revenue (~$0.2M), large net loss (~-$83.0M), and heavy negative free cash flow (~-$64.6M). Balance sheet leverage is low (debt-to-equity ~0.10) with positive equity (~$106.2M), but equity/assets have trended down, indicating ongoing capital erosion risk if cash burn continues.
Income Statement
8
Very Negative
Balance Sheet
56
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue225.00K0.000.000.000.000.00
Gross Profit326.00K-8.44M-8.47M-8.69M-8.71M-4.03M
EBITDA-75.47M-82.16M-102.66M-115.40M-114.95M-68.70M
Net Income-83.00M-90.60M-111.13M-124.08M-123.67M-72.72M
Balance Sheet
Total Assets135.07M146.92M119.94M170.51M278.94M316.65M
Cash, Cash Equivalents and Short-Term Investments80.89M100.55M61.45M104.64M186.53M251.30M
Total Debt10.12M10.83M13.61M12.42M15.10M15.70M
Total Liabilities28.88M23.66M27.09M31.09M35.57M38.12M
Stockholders Equity106.19M123.27M92.85M139.42M243.38M278.53M
Cash Flow
Free Cash Flow-64.63M-68.88M-91.53M-103.31M-125.05M-85.93M
Operating Cash Flow-64.39M-68.26M-90.50M-102.07M-104.42M-60.81M
Investing Cash Flow33.77M56.08M1.13M48.72M83.65M-238.56M
Financing Cash Flow57.73M108.41M47.75M4.05M77.77M208.97M

Tenaya Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.33
Price Trends
50DMA
0.77
Negative
100DMA
0.75
Negative
200DMA
1.01
Negative
Market Momentum
MACD
-0.03
Positive
RSI
43.50
Neutral
STOCH
22.98
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TNYA, the sentiment is Negative. The current price of 1.33 is above the 20-day moving average (MA) of 0.76, above the 50-day MA of 0.77, and above the 200-day MA of 1.01, indicating a bearish trend. The MACD of -0.03 indicates Positive momentum. The RSI at 43.50 is Neutral, neither overbought nor oversold. The STOCH value of 22.98 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TNYA.

Tenaya Therapeutics Risk Analysis

Tenaya Therapeutics disclosed 67 risk factors in its most recent earnings report. Tenaya Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Tenaya Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$322.02M4.8441.40%
55
Neutral
$583.96M-60.42%26.28%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$566.26M-6.76-32.33%38.99%
48
Neutral
$147.56M-1.31-80.56%59.42%
44
Neutral
$213.29M-1.85-55.97%-45.50%-35.63%
41
Neutral
$173.86M-6.9421.05%43.38%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TNYA
Tenaya Therapeutics
0.71
0.13
23.01%
GALT
Galectin Therapeutics
2.77
-0.52
-15.81%
ABEO
Abeona Therapeutics
5.65
-0.35
-5.83%
VYGR
Voyager Therapeutics
3.62
0.58
19.08%
TECX
Tectonic Therapeutic
30.06
10.26
51.82%
CADL
Candel Therapeutics
7.99
3.07
62.40%

Tenaya Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
Tenaya Therapeutics Shareholders Approve Expanded Equity Incentive Plan
Positive
May 29, 2026
On May 27, 2026, Tenaya Therapeutics’ shareholders approved an amended and restated 2021 Equity Incentive Plan, adding a one-time increase of about 6.5 million shares, equal to roughly 3% of outstanding stock, and revising the evergreen prov...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 30, 2026