Product DevelopmentThe next-generation RASP modulator ADX-248 is being expanded to include CNS neuroinflammatory diseases, based on preclinical progress in Parkinson's models and amyotrophic lateral sclerosis.
Regulatory ApprovalApproval is likely as the FDA recognizes Reproxalap as a differentiated DED drug with a disease-modifying mechanism resulting in treatment effects seen within minutes.
Strategic PartnershipsA potential commercial relationship with AbbVie seems a significant positive for the prospects of reproxalap as the AbbVie partnership is likely needed for Reproxalap to gain timely patient access and reimbursement.