Development ChallengesCandel has paused their development of CAN-2409 for borderline resectable pancreatic ductal adenocarcinoma, despite the encouraging 31.4mo mOS in the phase 2 study.
Durability Of ResponseWhile these results validate CAN-3110’s mechanism, durability of response and reproducibility remain open questions.
Integration Into TreatmentLingering questions remain regarding the optimal integration of CAN-2409 into current treatment paradigms, and the durability of disease-free survival improvement within subgroup analyses will need clarification with longer follow-up.