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Pfizer (PFE)
NYSE:PFE

Pfizer (PFE) AI Stock Analysis

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PF

Pfizer

(NYSE:PFE)

Rating:72Outperform
Price Target:
$27.00
▲(11.62%Upside)
Pfizer's overall score is primarily driven by its solid financial performance and attractive valuation, enhanced by positive technical indicators. Despite some revenue decline and external challenges highlighted in the earnings call, the company's strategic focus and operational efficiency support a stable outlook.
Positive Factors
Business Strategy
A number of transformative acquisitions completed using the windfall of COVID cash bolster the company's pipeline.
Financial Performance
The analyst's Outperform rating on Pfizer shares is supported by the analysis suggesting that the shares are undervalued given potentially better fundamentals relative to U.S. BioPharma peers.
Product Development
Pfizer's KAT6 inhibitor has demonstrated strong responses at ASCO with objective response rate of around 37% and median progression-free survival of 10.7 months in ER+/HER2- metastatic breast cancer.
Negative Factors
Market Competition
Efficacy with the go-forward dose of PDL1V monotherapy appears undifferentiated compared to other ADCs in the relapsed/refractory metastatic NSCLC space.
Product Safety
Patients receiving the Braftovi combination therapy experienced more adverse events compared to those on standard-of-care.

Pfizer (PFE) vs. SPDR S&P 500 ETF (SPY)

Pfizer Business Overview & Revenue Model

Company DescriptionPfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products worldwide. It offers medicines and vaccines in various therapeutic areas, including cardiovascular metabolic and women's health under the Premarin family and Eliquis brands; biologics, small molecules, immunotherapies, and biosimilars under the Ibrance, Xtandi, Sutent, Inlyta, Retacrit, Lorbrena, and Braftovi brands; and sterile injectable and anti-infective medicines, and oral COVID-19 treatment under the Sulperazon, Medrol, Zavicefta, Zithromax, Vfend, Panzyga, and Paxlovid brands. The company also provides medicines and vaccines in various therapeutic areas, such as pneumococcal disease, meningococcal disease, tick-borne encephalitis, and COVID-19 under the Comirnaty/BNT162b2, Nimenrix, FSME/IMMUN-TicoVac, Trumenba, and the Prevnar family brands; biosimilars for chronic immune and inflammatory diseases under the Xeljanz, Enbrel, Inflectra, Eucrisa/Staquis, and Cibinqo brands; and amyloidosis, hemophilia, and endocrine diseases under the Vyndaqel/Vyndamax, BeneFIX, and Genotropin brands. In addition, the company is involved in the contract manufacturing business. It serves wholesalers, retailers, hospitals, clinics, government agencies, pharmacies, and individual provider offices, as well as disease control and prevention centers. The company has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma US, Inc.; Myovant Sciences Ltd.; Akcea Therapeutics, Inc; Merck KGaA; Valneva SE; BioNTech SE; and Arvinas, Inc. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.
How the Company Makes MoneyPfizer makes money primarily through the sale of pharmaceutical products, which is its largest revenue stream. The company's revenue model is based on the development and commercialization of patented drugs, which are sold to hospitals, pharmacies, and directly to healthcare providers. Key revenue streams include its blockbuster drugs and vaccines, such as those in oncology, vaccines (including the COVID-19 vaccine), and rare diseases. Pfizer also generates revenue through strategic partnerships and collaborations with other pharmaceutical companies and research institutions, which help in the development and distribution of new therapies. Additionally, Pfizer invests heavily in research and development to sustain its pipeline of future products, ensuring a continuous flow of new revenue-generating medicines.

Pfizer Earnings Call Summary

Earnings Call Date:Apr 29, 2025
(Q1-2025)
|
% Change Since: 6.94%|
Next Earnings Date:Aug 05, 2025
Earnings Call Sentiment Neutral
Pfizer's earnings call highlighted a strong R&D pipeline and strategic focus on growth areas such as oncology and cardiometabolic segments, alongside significant growth in key products. However, the company also faced challenges, including a decline in overall revenue and potential impacts from global trade uncertainties and competition. Despite these challenges, Pfizer demonstrated strong operational efficiency and cost management, positioning itself for future growth.
Q1-2025 Updates
Positive Updates
Strong R&D Pipeline and Strategic Focus
Pfizer emphasized strengthening its R&D organization with a focus on cardiometabolic and oncology segments. Anticipated multiple key milestones include at least four regulatory decisions and up to nine phase three readouts in 2025.
Significant Revenue Growth in Key Products
The Vintechl family of products saw robust growth, and the oncology portfolio, specifically Tatsit, grew by 25% in revenue. The company also reported a 40% revenue growth for Northrop America.
Operational Efficiency and Cost Management
Pfizer reported a 12% operational decline in total adjusted operating expenses and is on track to deliver $4.5 billion in cumulative net cost savings by the end of 2025.
Strong Performance in US and International Markets
Pfizer reported strong contributions across its product portfolio and noted significant market growth in international regions, particularly with products like Nortech, Tatsit, and Blurbbrand.
Negative Updates
6% Decline in Revenue
Pfizer's revenues for the first quarter of 2025 were $13.7 billion, marking a 6% operational decline primarily due to lower PAX load revenues and changes in the IRA Medicare Part D redesign.
Impact of Competition on Vintechl
Despite robust growth, the Vintechl family faced competition with new market entrants, impacting newly diagnosed patients.
Challenges with Tariffs and Global Uncertainty
The pharmaceutical industry is navigating a complex global landscape with potential tariffs and trade policy changes, which could impact Pfizer's operations.
Company Guidance
During Pfizer Inc.'s First Quarter 2025 Earnings Conference Call, the company reaffirmed its guidance for the fiscal year 2025, projecting total company revenues to be in the range of $61 to $64 billion and adjusted diluted earnings per share between $2.80 and $3.00. The call highlighted Pfizer's focus on improving R&D productivity, with anticipated milestones including at least four regulatory decisions and up to nine phase three readouts. The company reported first-quarter revenues of $13.7 billion, a 6% operational decline, primarily due to lower PAXLOVID revenues and changes in the IRA Medicare Part D redesign. However, Pfizer recorded strong growth in several key products, with adjusted diluted earnings per share reaching $0.92, attributed to robust gross margin and cost management. The company also emphasized its strategic priorities of enhancing shareholder value, maintaining a strong dividend policy, and pursuing disciplined capital allocation with reinvestments in R&D and potential external opportunities, despite the macroeconomic uncertainties such as potential tariffs and the complex global trade environment.

Pfizer Financial Statement Overview

Summary
Pfizer demonstrates solid financial health with strong margins and cash flow generation capabilities. Despite a recent dip in revenue growth and ROE, the company maintains a stable balance sheet with a manageable debt level. Continued focus on operational efficiencies and strategic investments will be key to sustaining growth and improving profitability.
Income Statement
65
Positive
Pfizer's income statement reflects a strong gross profit margin of 67.38% for TTM, indicating efficient cost management. However, there is a decline in revenue growth with a decrease of 1.83% from the previous annual report. The net profit margin stands at 12.60% for TTM, showing profitability but lower than the peak in 2022. EBIT and EBITDA margins are healthy at 23.65% and 27.59% respectively, yet have decreased from prior years, signaling potential challenges in maintaining operational efficiency.
Balance Sheet
70
Positive
The balance sheet indicates a stable financial structure with a debt-to-equity ratio of 0.68, which is manageable. The equity ratio is at 43.42%, showcasing a solid equity base relative to total assets. Return on equity for TTM is 8.71%, reflecting decent profitability on shareholder investment, though it has declined from previous years, suggesting room for improvement in generating returns.
Cash Flow
60
Neutral
Cash flow analysis shows strong free cash flow generation, with a growth rate of 14.11% from the previous year, highlighting robust cash generation capabilities. The operating cash flow to net income ratio is 1.78, indicating good conversion of income to cash. However, the free cash flow to net income ratio is 1.43, suggesting some limitations in free cash flow relative to net income, which may affect future investment or debt repayment flexibility.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue62.46B63.63B58.50B100.33B81.29B41.91B
Gross Profit42.09B47.21B28.81B65.99B50.47B33.22B
EBITDA17.23B18.13B9.56B41.03B30.79B13.17B
Net Income7.87B8.03B2.12B31.37B21.98B7.02B
Balance Sheet
Total Assets208.03B213.40B226.50B197.21B181.48B154.23B
Cash, Cash Equivalents and Short-Term Investments17.32B20.48B12.69B22.73B31.07B12.22B
Total Debt61.29B63.65B70.84B34.87B37.00B38.27B
Total Liabilities117.39B124.90B137.21B101.29B104.01B90.76B
Stockholders Equity90.34B88.20B89.01B95.66B77.20B63.24B
Cash Flow
Free Cash Flow11.22B9.84B4.79B26.03B29.87B11.61B
Operating Cash Flow13.99B12.74B8.70B29.27B32.58B14.40B
Investing Cash Flow4.19B2.65B-32.28B-15.78B-22.55B-4.27B
Financing Cash Flow-17.44B-17.14B26.07B-14.83B-9.82B-9.65B

Pfizer Technical Analysis

Technical Analysis Sentiment
Positive
Last Price24.19
Price Trends
50DMA
23.26
Positive
100DMA
24.03
Positive
200DMA
25.14
Negative
Market Momentum
MACD
0.25
Positive
RSI
56.12
Neutral
STOCH
44.46
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PFE, the sentiment is Positive. The current price of 24.19 is above the 20-day moving average (MA) of 23.98, above the 50-day MA of 23.26, and below the 200-day MA of 25.14, indicating a neutral trend. The MACD of 0.25 indicates Positive momentum. The RSI at 56.12 is Neutral, neither overbought nor oversold. The STOCH value of 44.46 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PFE.

Pfizer Risk Analysis

Pfizer disclosed 26 risk factors in its most recent earnings report. Pfizer reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Pfizer Peers Comparison

Overall Rating
UnderperformOutperform
Sector (60)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
MRMRK
78
Outperform
$200.05B11.6039.31%4.11%4.40%654.93%
JNJNJ
75
Outperform
$365.75B16.9329.45%3.42%-0.37%29.21%
AZAZN
73
Outperform
$218.28B27.7919.81%3.00%15.48%22.70%
73
Outperform
$327.47B79.0588.15%3.51%5.45%-30.21%
PFPFE
72
Outperform
$137.93B17.588.62%7.09%13.38%
71
Outperform
$150.75B25.59105.67%3.40%15.59%56.99%
60
Neutral
HK$15.14B5.55-7.43%5.48%11.72%-20.69%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PFE
Pfizer
24.19
-2.04
-7.78%
AMGN
Amgen
277.13
-25.55
-8.44%
AZN
AstraZeneca
69.85
-6.60
-8.63%
JNJ
Johnson & Johnson
152.41
10.86
7.67%
MRK
Merck & Company
79.10
-40.66
-33.95%
ABBV
AbbVie
182.31
16.80
10.15%

Pfizer Corporate Events

Private Placements and FinancingBusiness Operations and Strategy
Pfizer Completes €3.3 Billion Notes Offering
Neutral
May 19, 2025

On May 19, 2025, Pfizer Netherlands International Finance B.V., a subsidiary of Pfizer Inc., completed a public offering of €3.3 billion in aggregate principal amount of notes with varying maturity dates and interest rates. This strategic financial move, backed by a senior unsecured guarantee from Pfizer Inc., is part of the company’s broader financial strategy to strengthen its market position and ensure operational liquidity.

The most recent analyst rating on (PFE) stock is a Hold with a $30.00 price target. To see the full list of analyst forecasts on Pfizer stock, see the PFE Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 25, 2025