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22nd Century (XXII)
NASDAQ:XXII
US Market
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22nd Century (XXII) AI Stock Analysis

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XXII

22nd Century

(NASDAQ:XXII)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
$4.50
▲(492.11% Upside)
Action:Reiterated
Date:06/23/26
The score is held down primarily by weak financial performance (negative gross profit, ongoing operating losses, and continued cash burn) and a clearly bearish technical setup despite oversold readings. Earnings-call guidance shows measurable commercial progress and a clearer execution plan, but near-term profitability is still deteriorating. Valuation provides limited support due to losses (negative P/E) and no dividend.
Positive Factors
Balance Sheet Strength
Leverage has materially improved with very low debt relative to equity and positive shareholders' equity. This strengthens financial flexibility to fund commercialization and marketing investments over the next 2–6 months without meaningfully increasing interest burden, lowering solvency risk.
Negative Factors
Persistent Cash Burn
The company remains cash-consuming on a trailing-twelve-month basis, requiring ongoing external funding for operations. Continued negative operating and free cash flow constrains reinvestment options and makes the execution of distribution and marketing plans contingent on securing financing.
Read all positive and negative factors
Positive Factors
Negative Factors
Balance Sheet Strength
Leverage has materially improved with very low debt relative to equity and positive shareholders' equity. This strengthens financial flexibility to fund commercialization and marketing investments over the next 2–6 months without meaningfully increasing interest burden, lowering solvency risk.
Read all positive factors

22nd Century (XXII) vs. SPDR S&P 500 ETF (SPY)

22nd Century Business Overview & Revenue Model

Company Description
22nd Century Group, Inc. is an agricultural biotechnology firm dedicated to mitigating the risks associated with tobacco use and improving health and wellness through advanced plant science. The company serves the life science and consumer product...
How the Company Makes Money
22nd Century makes money primarily through (1) sales of tobacco-related products and materials derived from its proprietary tobacco plant technology and (2) sales and services related to hemp/cannabis processing and ingredients when those operatio...

22nd Century Earnings Call Summary

Earnings Call Date:May 07, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 19, 2026
Earnings Call Sentiment Neutral
The call conveyed cautious optimism: management reported clear early commercial progress with sequential revenue growth, gross loss improvement, strategic retail distribution wins, regulatory validation (FDA authorization) and a stable cash position. However, material challenges remain — operating losses and negative adjusted EBITDA widened, profitability is below targets, low-margin contracts persist, and retail adoption is uneven. Management plans focused investments in marketing and distribution with a target of ~5,000 outlets by year-end, but execution risk and competitive headwinds mean near-term results may continue to be pressured.
Positive Updates
Sequential Revenue Growth
Net revenue of $4.1M in Q1 2026, up from $3.5M in Q4 2025 — a sequential increase of approximately 16.1%.
Negative Updates
Ongoing Operating Losses
Operating loss was $3.0M in Q1 2026 versus $2.8M in Q4 2025 (increase of $0.2M, ~7.1% worse); net loss from continuing operations also $3.0M versus $2.8M prior quarter.
Read all updates
Q1-2026 Updates
Negative
Sequential Revenue Growth
Net revenue of $4.1M in Q1 2026, up from $3.5M in Q4 2025 — a sequential increase of approximately 16.1%.
Read all positive updates
Company Guidance
The company guided to a 2026 execution-focused plan centered on scaling retail distribution and investing in consumer marketing, with specific near-term targets and metrics: Q1 2026 revenue was $4.1M (up ~16.1% sequentially from $3.5M in Q4 2025), gross loss improved to $0.6M (from $0.8M), operating loss and net loss were each $3.0M (vs. $2.8M), adjusted EBITDA was negative $2.6M (vs. negative $2.4M), and cash and equivalents stood at $9.5M; commercial targets include expanding to more than 5,000 retail outlets by year-end 2026, adding roughly 200 outlets in New York/New Jersey/Southern California in Q2/Q3, initial Southeast shipments in late Q3/early Q4, hiring a VP of Marketing and additional sales/marketing headcount, exiting low/no-margin contracts and prioritizing capital toward distribution growth, VLN commercial support, marketing initiatives and the reduced-nicotine pipeline, with the company expecting stronger commercial momentum in the back half of 2026.

22nd Century Financial Statement Overview

Summary
Revenue is improving and losses have narrowed, and leverage is now low with positive equity. However, fundamentals remain weak with negative gross profit, persistent operating losses, and continued cash burn (negative operating cash flow and free cash flow), keeping financial risk elevated.
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
10
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue8.88M7.05M11.88M32.20M40.50M30.95M
Gross Profit-3.25M-3.14M-2.40M-8.70M1.85M1.49M
EBITDA-10.87M-10.53M-12.11M-40.41M-32.89M-31.00M
Net Income-3.99M-5.05M-15.16M-140.78M-59.80M-32.61M
Balance Sheet
Total Assets30.31M27.02M21.67M27.50M114.65M75.95M
Cash, Cash Equivalents and Short-Term Investments9.54M7.15M4.42M2.06M20.40M48.74M
Total Debt1.32M4.21M8.62M16.38M4.65M2.34M
Total Liabilities9.09M11.27M17.66M35.91M18.68M9.88M
Stockholders Equity21.22M15.76M4.01M-8.41M95.97M66.07M
Cash Flow
Free Cash Flow-7.94M-8.60M-14.51M-60.60M-56.14M-23.91M
Operating Cash Flow-7.85M-7.72M-14.35M-54.99M-51.71M-22.84M
Investing Cash Flow-493.00K-505.00K-139.00K16.82M22.58M-27.73M
Financing Cash Flow16.75M10.96M16.85M37.21M30.82M50.88M

22nd Century Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.76
Price Trends
50DMA
19.23
Negative
100DMA
54.09
Negative
200DMA
213.66
Negative
Market Momentum
MACD
-4.25
Negative
RSI
19.30
Positive
STOCH
2.49
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For XXII, the sentiment is Negative. The current price of 0.76 is below the 20-day moving average (MA) of 8.60, below the 50-day MA of 19.23, and below the 200-day MA of 213.66, indicating a bearish trend. The MACD of -4.25 indicates Negative momentum. The RSI at 19.30 is Positive, neither overbought nor oversold. The STOCH value of 2.49 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for XXII.

22nd Century Risk Analysis

22nd Century disclosed 33 risk factors in its most recent earnings report. 22nd Century reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

22nd Century Peers Comparison

Overall Rating
UnderperformOutperform
Sector (62)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
$20.33B14.63-3.31%3.23%1.93%-12.26%
62
Neutral
$1.59B28.4317.29%0.28%16.10%26.07%
53
Neutral
$1.30B40.042.24%6.15%-0.77%-65.72%
49
Neutral
$113.65M-3.32546.10%-38.18%-21.59%
42
Neutral
$1.60M-0.69-25.03%-34.08%99.49%
41
Neutral
$1.62M-0.10-162.57%-66.04%99.58%
40
Underperform
$636.85K-0.05-247.42%-78.48%14.33%
* Consumer Defensive Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
XXII
22nd Century
4.49
-2,428.51
-99.82%
UVV
Universal
51.51
-4.53
-8.08%
TPB
Turning Point Brands
75.45
0.71
0.95%
GNLN
Greenlane Holdings
2.61
-22.03
-89.41%
KAVL
Kaival Brands Innovations Group
0.03
-0.49
-93.90%
ISPR
Ispire Technology, Inc.
1.87
-0.59
-23.98%

22nd Century Corporate Events

Executive/Board ChangesShareholder Meetings
22nd Century Shareholders Back Board, Pay and Auditor Plans
Positive
Jun 11, 2026
At its 2026 Annual Meeting of Stockholders held on June 11, 2026, 22nd Century Group, Inc. shareholders elected Lucille Salhany as a Class III director to serve until the 2029 annual meeting, reinforcing board continuity and governance stability. ...
Delistings and Listing ChangesPrivate Placements and FinancingRegulatory Filings and ComplianceStock Split
22nd Century Announces Reverse Split and Warrant Inducement
Neutral
Jun 9, 2026
On June 8, 2026, 22nd Century launched a warrant inducement with holders of outstanding warrants exercisable at $3.57, offering a reduced cash exercise price of $0.4626 and issuing new inducement warrants on substantially similar terms, including ...
Private Placements and FinancingRegulatory Filings and Compliance
22nd Century Files Prospectus for Potential ATM Stock Offering
Neutral
May 1, 2026
On May 1, 2026, 22nd Century Group, Inc. filed a prospectus supplement with the U.S. Securities and Exchange Commission to enable the sale of up to $6.4 million of its common stock under an existing sales agreement with Needham Company, LLC. As o...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 23, 2026