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Viridian Therapeutics (VRDN)
NASDAQ:VRDN
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Viridian Therapeutics (VRDN) AI Stock Analysis

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VRDN

Viridian Therapeutics

(NASDAQ:VRDN)

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Neutral 59 (OpenAI - 4o)
Rating:59Neutral
Price Target:
$33.00
▲(4.04% Upside)
Viridian Therapeutics' stock score is primarily influenced by its strong technical momentum, despite financial challenges. The company's financial performance is weak due to ongoing losses and cash flow issues, but the technical indicators show bullish trends. Valuation remains a concern with a negative P/E ratio, reflecting the company's current unprofitability.
Positive Factors
Revenue Growth
The company's substantial revenue growth indicates strong market demand for its products, which can lead to increased market share and long-term sustainability.
Low Leverage
Low leverage provides financial stability and flexibility, allowing the company to invest in growth opportunities without the burden of high debt costs.
Innovative Product Pipeline
A focus on innovative therapies for rare diseases positions the company as a leader in niche markets, potentially leading to high-margin products and competitive advantage.
Negative Factors
Profitability Concerns
Ongoing profitability issues can hinder the company's ability to reinvest in R&D and may require additional capital raises, diluting shareholder value.
Cash Flow Challenges
Negative cash flow limits the company's ability to fund operations and growth initiatives internally, increasing reliance on external financing.
Operating Losses
High operating losses reflect the costs associated with development stages, which can strain financial resources and delay profitability.

Viridian Therapeutics (VRDN) vs. SPDR S&P 500 ETF (SPY)

Viridian Therapeutics Business Overview & Revenue Model

Company DescriptionViridian Therapeutics, Inc., a biotechnology company, develops treatments for patients suffering from serious diseases. It develops VRDN-001, a humanized monoclonal anti-IGF-1R antibody that is in Phase 1/2 clinical trial for the treatment of thyroid eye disease (TED); VRDN-002, an IGF-1R antibody, which is in Phase 1 clinical trial; and VRDN-003, a therapeutic antibody targeting IGF-1R for the treatment of TED. The company was formerly known as Miragen Therapeutics, Inc. and changed its name to Viridian Therapeutics, Inc. in January 2021. Viridian Therapeutics, Inc. was founded in 2006 and is headquartered in Waltham, Massachusetts.
How the Company Makes MoneyViridian Therapeutics generates revenue primarily through the development and commercialization of its therapeutic products. The company's revenue model includes potential sales from approved drugs, milestone payments from partnerships, and royalties on product sales. Key revenue streams may arise from collaborations with larger pharmaceutical companies that provide funding for research and development in exchange for future profits or product rights. Additionally, Viridian may seek to monetize its product pipeline through licensing agreements or partnerships that allow it to share development costs and risks while gaining access to broader distribution channels.

Viridian Therapeutics Earnings Call Summary

Earnings Call Date:May 08, 2024
(Q1-2024)
|
% Change Since: |
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Positive
The earnings call reflects significant progress and positive developments in the company's pipeline, particularly with the completion of enrollment in the THRIVE trial, a strong financial position, and positive regulatory interactions. However, there are challenges, such as the extended timeline for BLA submission and concerns about hearing impairment assessments in clinical trials.
Q1-2024 Updates
Positive Updates
Completion of THRIVE Phase III Enrollment
The THRIVE Phase III trial evaluating 001 in patients with active TED completed enrollment ahead of schedule with 113 patients, exceeding the target of 90 due to strong patient demand.
Strong Financial Position
Viridian ended the quarter with $613 million in cash, cash equivalents, and short-term investments, maintaining a cash runway into the second half of 2026.
Positive FDA Meeting for Subcutaneous 003 Program
The company completed a positive Type C meeting with the FDA for the subcutaneous 003 program and is on track to initiate pivotal clinical trials midyear.
Progress in FcRn Portfolio
Viridian is making progress with its FcRn portfolio, aiming to file an IND for 006 by the end of the year, and plans to share 008 nonhuman primate data in the second half of 2024.
Negative Updates
Extended Timeline for BLA Submission
The BLA submission for the 001 program is anticipated in the second half of 2025, driven primarily by the extended follow-up period in the THRIVE 2 trial.
Challenges in Hearing Impairment Assessment
There are concerns about controlling for hearing impairment events in the THRIVE study due to factors already present in TED patients.
Company Guidance
During Viridian Therapeutics' Q1 2024 earnings call, the company provided several updates on their pipeline and financial outlook. Viridian announced the completion of enrollment for their THRIVE Phase III trial for the 001 IV program, surpassing the target with 113 patients. They anticipate top-line results in September 2024 and plan a BLA submission for the 001 program in the second half of 2025. The company also highlighted progress in their FcRn portfolio, with an IND for 006 expected by the end of 2024 and 008 nonhuman primate data anticipated in the second half of 2024. Viridian ended the quarter with $613 million in cash, cash equivalents, and short-term investments, maintaining a cash runway into the second half of 2026.

Viridian Therapeutics Financial Statement Overview

Summary
Viridian Therapeutics is experiencing significant revenue growth, but profitability and cash flow remain challenging. The balance sheet is stable with low leverage, yet ongoing losses could pose risks if not addressed. The company should focus on improving operational efficiency and cash flow management.
Income Statement
30
Negative
Viridian Therapeutics shows significant revenue growth in the TTM period, but profitability remains a major concern with negative net profit margins and EBIT margins. The company is experiencing high operating losses, which is typical for biotechnology firms in the development phase.
Balance Sheet
45
Neutral
The company maintains a low debt-to-equity ratio, indicating conservative leverage. However, the negative return on equity reflects ongoing losses, which could be a risk if not managed well. The equity ratio is stable, suggesting a solid asset base relative to liabilities.
Cash Flow
35
Negative
Free cash flow is negative, but there is slight growth in the TTM period. The operating cash flow to net income ratio is unfavorable, indicating cash flow challenges. The company needs to improve cash generation to support its operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue70.79M302.00K314.00K1.77M2.96M1.05M
Gross Profit70.79M302.00K314.00K1.77M2.96M-27.25M
EBITDA-298.99M-265.66M-235.37M-129.13M-79.29M-40.28M
Net Income-301.97M-269.95M-237.73M-129.87M-79.41M-110.72M
Balance Sheet
Total Assets577.14M742.40M490.42M435.09M203.71M131.25M
Cash, Cash Equivalents and Short-Term Investments490.90M717.58M477.37M424.55M196.97M127.64M
Total Debt23.82M21.09M21.05M5.26M520.00K455.00K
Total Liabilities74.17M70.76M48.40M40.03M15.99M11.22M
Stockholders Equity502.97M671.64M442.02M395.06M187.72M120.04M
Cash Flow
Free Cash Flow-326.34M-232.83M-185.07M-94.64M-54.92M-29.82M
Operating Cash Flow-325.97M-232.32M-184.17M-93.84M-54.58M-29.78M
Investing Cash Flow238.94M-228.65M-94.25M-115.13M-74.29M-50.48M
Financing Cash Flow56.36M457.74M225.67M322.24M125.28M101.31M

Viridian Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price31.72
Price Trends
50DMA
24.01
Positive
100DMA
20.98
Positive
200DMA
17.66
Positive
Market Momentum
MACD
2.22
Negative
RSI
76.63
Negative
STOCH
81.98
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VRDN, the sentiment is Positive. The current price of 31.72 is above the 20-day moving average (MA) of 27.79, above the 50-day MA of 24.01, and above the 200-day MA of 17.66, indicating a bullish trend. The MACD of 2.22 indicates Negative momentum. The RSI at 76.63 is Negative, neither overbought nor oversold. The STOCH value of 81.98 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for VRDN.

Viridian Therapeutics Risk Analysis

Viridian Therapeutics disclosed 68 risk factors in its most recent earnings report. Viridian Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Viridian Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$2.10B-5.29-47.40%23340.07%18.06%
56
Neutral
$2.09B-12.48%-23.37%-42.45%
55
Neutral
$1.32B-10.20-28.57%-42.64%-39.78%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
42
Neutral
$1.78B-51.81%-20.08%
40
Underperform
$2.70B-30.02%-5.73%
40
Underperform
$1.00B-522.08%18.76%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VRDN
Viridian Therapeutics
31.96
10.96
52.19%
DNTH
Dianthus Therapeutics
44.03
18.33
71.32%
PHVS
Pharvaris
27.72
8.57
44.75%
EWTX
Edgewise Therapeutics
25.52
-6.02
-19.09%
JANX
Janux Therapeutics Inc
34.69
-5.49
-13.66%
BHVN
Biohaven Ltd.
9.48
-35.26
-78.81%

Viridian Therapeutics Corporate Events

Viridian Therapeutics Advances Toward Profitability with Strategic Moves
Nov 7, 2025

Viridian Therapeutics, Inc. is a biotechnology company dedicated to discovering, developing, and commercializing potentially best-in-class medicines for serious and rare diseases, with a focus on thyroid eye disease (TED) and neonatal Fc receptor (FcRn) inhibitors.

Viridian Therapeutics’ Promising Phase 3 Trial for Thyroid Eye Disease
Oct 27, 2025

Viridian Therapeutics, Inc. is conducting a Phase 3 clinical trial titled ‘A Randomized, Open-label Study Evaluating the Safety, Tolerability and Pharmacokinetics of VRDN-003 Administered Subcutaneously in Participants With Thyroid Eye Disease (TED).’ The study aims to assess the safety, tolerability, and pharmacokinetics of VRDN-003, a humanized monoclonal antibody targeting the IGF-1 receptor, in individuals with Thyroid Eye Disease. This trial is significant as it could offer a new therapeutic option for TED, a condition with limited treatment options.

Viridian Therapeutics Advances VRDN-003 Study for Thyroid Eye Disease
Oct 27, 2025

Viridian Therapeutics, Inc. is conducting a clinical study titled A Randomized, Double-masked, Controlled, Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED). The study aims to evaluate the safety and tolerability of VRDN-003, a potential treatment for TED, a condition that affects the eyes of people with thyroid disorders. This study is significant as it could lead to a new therapeutic option for TED patients.

Private Placements and Financing
Viridian Therapeutics Announces Stock Sale Agreement
Neutral
Oct 23, 2025

On October 21, 2025, Viridian Therapeutics announced an underwriting agreement for the sale of 11,425,000 shares of common stock at $22.00 per share, potentially raising approximately $251.35 million. The proceeds, combined with other financial resources, are expected to fund the company’s operations, including anticipated revenue from product sales and milestone payments, although the company acknowledges potential risks and uncertainties in its financial projections.

The most recent analyst rating on (VRDN) stock is a Hold with a $24.50 price target. To see the full list of analyst forecasts on Viridian Therapeutics stock, see the VRDN Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Viridian Therapeutics Secures $300M Deal with DRI Healthcare
Positive
Oct 20, 2025

On October 17, 2025, Viridian Therapeutics entered into a Purchase and Sale Agreement with DRI Healthcare Acquisitions, selling rights to certain revenue streams in the U.S. for up to $300 million. This agreement includes payments contingent on achieving specific clinical and regulatory milestones for its products VRDN-003 and veligrotug. Additionally, Viridian amended its Loan and Security Agreement with Hercules Capital, securing a new term loan facility of up to $300 million, structured in tranches contingent on regulatory and revenue milestones, with a maturity date set for October 17, 2030.

The most recent analyst rating on (VRDN) stock is a Buy with a $46.00 price target. To see the full list of analyst forecasts on Viridian Therapeutics stock, see the VRDN Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 25, 2025