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Aurinia Pharmaceuticals (AUPH)
NASDAQ:AUPH
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Aurinia Pharmaceuticals (AUPH) AI Stock Analysis

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AUPH

Aurinia Pharmaceuticals

(NASDAQ:AUPH)

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Outperform 79 (OpenAI - 4o)
Rating:79Outperform
Price Target:
$16.50
▲(0.79% Upside)
Aurinia Pharmaceuticals' strong financial performance and positive earnings call are the most significant factors driving the stock's score. The company's robust revenue growth, profitability improvements, and promising clinical developments are key strengths. However, technical indicators suggest the stock may be overbought, and its high P/E ratio indicates a premium valuation, which could limit further upside.
Positive Factors
Revenue Growth
The strong growth in LUPKYNIS sales indicates robust demand and effective market penetration, supporting long-term revenue expansion and financial stability.
Cash Flow Generation
Significant improvement in cash flow generation enhances financial flexibility, enabling strategic investments and reducing reliance on external financing.
Clinical Developments
Progress in clinical developments for aritinercept suggests potential for future product diversification and revenue streams, strengthening the company's pipeline.
Negative Factors
Regulatory Challenges
Regulatory inquiries can lead to delays or additional compliance costs, impacting the company's ability to maintain product momentum and market confidence.
Legal Proceedings
Ongoing legal disputes may divert management attention and resources, potentially affecting strategic focus and operational efficiency.
Historical Volatility
Past financial volatility could signal underlying operational risks, potentially affecting future performance consistency and investor confidence.

Aurinia Pharmaceuticals (AUPH) vs. SPDR S&P 500 ETF (SPY)

Aurinia Pharmaceuticals Business Overview & Revenue Model

Company DescriptionAurinia Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for autoimmune and kidney diseases. The company's primary product, LUPKYNIS (voclosporin), is an FDA-approved treatment for lupus nephritis, a serious and potentially life-threatening condition. Aurinia is committed to advancing medical science by conducting rigorous clinical trials and engaging with healthcare professionals to improve patient outcomes in underserved areas of medicine.
How the Company Makes MoneyAurinia Pharmaceuticals generates revenue primarily through the sale of its flagship product, LUPKYNIS, which is prescribed to patients with lupus nephritis. The company has established a revenue model that includes direct sales to healthcare providers, as well as potential partnerships and collaborations with pharmaceutical distributors and other stakeholders in the healthcare sector. Additionally, Aurinia may receive milestone payments and royalties from licensing agreements related to its product and technology. The company's financial performance can also be influenced by factors such as market demand for lupus nephritis treatments, reimbursement policies from insurance providers, and the overall competitive landscape in the biopharmaceutical industry.

Aurinia Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 04, 2026
Earnings Call Sentiment Positive
The earnings call showed strong sales growth and financial performance, particularly for LUPKYNIS, alongside promising clinical developments with aritinercept. However, regulatory and legal issues present potential challenges.
Q3-2025 Updates
Positive Updates
LUPKYNIS Sales Growth
LUPKYNIS sales grew at a rate of 27% for the quarter year-over-year, leading to an increase in sales guidance for 2025 to $265 million to $270 million.
Revenue and Net Income Increase
Total revenue for Q3 2025 was $73.5 million, up 8% from Q3 2024. Net income was $31.6 million, up 119% from $14.4 million in Q3 2024.
Cash Flow Surge
Cash flows from operating activities were $44.5 million, up 162% from $17 million in Q3 2024.
Positive Clinical Developments
Advancement of aritinercept towards clinical studies in 2 autoimmune diseases following positive Phase I results.
LUPKYNIS Efficacy Reinforced
New analyses show LUPKYNIS associated with a 53% reduction in the risk of renal-related events or death.
Negative Updates
FDA Information Request
Aurinia received an information request from the FDA regarding LUPKYNIS, though the content of the request was not disclosed, and the company believes the response was favorable.
Legal Proceedings
Aurinia filed a complaint against Dr. George Tidmarsh concerning statements about voclosporin, which is pending in the United States District Court.
Company Guidance
During Aurinia Pharmaceuticals' third quarter 2025 conference call, the company reported significant growth in LUPKYNIS sales, with a 27% year-over-year increase, prompting them to raise their 2025 sales guidance to $265 million to $270 million. Total revenue for the quarter reached $73.5 million, marking an 8% increase from the previous year, excluding a $10 million milestone payment from 2024. Net product sales of LUPKYNIS were $70.6 million, up from $55.5 million in 2024, and net income soared 119% to $31.6 million. The company also noted a 162% increase in cash flows from operating activities, reaching $44.5 million. Additionally, Aurinia is advancing aritinercept, a novel biologic, into clinical studies for two autoimmune diseases, following positive Phase I results. The company plans to provide more details on these initiatives in early 2026.

Aurinia Pharmaceuticals Financial Statement Overview

Summary
Aurinia Pharmaceuticals demonstrates a strong financial recovery with significant improvements in revenue growth, profitability, and cash flow generation. The company has effectively managed its debt levels, and its return on equity has improved substantially. While historical volatility in financial metrics presents some risk, the current trajectory suggests a positive outlook for the company.
Income Statement
85
Very Positive
Aurinia Pharmaceuticals has shown strong revenue growth with a TTM (Trailing-Twelve-Months) increase of 2.19% and a significant improvement in profitability metrics. The gross profit margin is robust at 89.51%, and the net profit margin has improved to 23.31% from a low of -80.71% in 2022. EBIT and EBITDA margins have also turned positive, indicating improved operational efficiency. However, the company has experienced volatility in past years, which poses a risk.
Balance Sheet
78
Positive
The balance sheet reflects a stable financial position with a manageable debt-to-equity ratio of 0.24. Return on equity has improved significantly to 16.72%, showcasing effective use of equity to generate profits. The equity ratio is healthy, indicating a strong capital structure. However, the company has had periods of negative ROE in the past, which could indicate potential risks if not managed well.
Cash Flow
82
Very Positive
Aurinia Pharmaceuticals has shown a strong free cash flow growth rate of 29.75% in the TTM, indicating improved cash generation capabilities. The operating cash flow to net income ratio of 1.18 suggests efficient cash conversion. The free cash flow to net income ratio is nearly 1, indicating that the company is effectively converting its profits into cash. Past fluctuations in cash flow metrics highlight potential volatility.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue265.81M235.13M175.51M134.03M45.60M50.12M
Gross Profit236.06M206.88M161.37M128.37M44.51M50.12M
EBITDA102.42M31.73M-63.05M-103.65M-177.44M-102.92M
Net Income77.84M5.75M-78.02M-108.18M-180.97M-102.68M
Balance Sheet
Total Assets527.53M550.64M548.06M470.86M543.37M463.66M
Cash, Cash Equivalents and Short-Term Investments351.81M358.48M350.49M389.39M466.08M398.33M
Total Debt78.21M79.37M97.61M8.09M8.74M8.41M
Total Liabilities161.76M173.17M170.11M65.42M64.28M55.91M
Stockholders Equity365.77M377.48M377.95M405.44M479.09M407.75M
Cash Flow
Free Cash Flow119.87M44.11M-34.18M-79.82M-159.19M-77.20M
Operating Cash Flow120.10M44.39M-33.46M-79.53M-157.69M-69.86M
Investing Cash Flow43.21M39.26M-6.71M-60.63M-103.87M-158.19M
Financing Cash Flow-127.27M-49.09M-5.13M2.43M221.11M194.38M

Aurinia Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price16.37
Price Trends
50DMA
13.11
Positive
100DMA
12.04
Positive
200DMA
10.04
Positive
Market Momentum
MACD
0.93
Negative
RSI
74.77
Negative
STOCH
94.79
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AUPH, the sentiment is Positive. The current price of 16.37 is above the 20-day moving average (MA) of 14.91, above the 50-day MA of 13.11, and above the 200-day MA of 10.04, indicating a bullish trend. The MACD of 0.93 indicates Negative momentum. The RSI at 74.77 is Negative, neither overbought nor oversold. The STOCH value of 94.79 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AUPH.

Aurinia Pharmaceuticals Risk Analysis

Aurinia Pharmaceuticals disclosed 35 risk factors in its most recent earnings report. Aurinia Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aurinia Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$2.16B29.1720.65%20.62%
59
Neutral
$2.03B-7.52%27.51%38.72%
57
Neutral
$1.65B57.0517.44%24.15%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$2.20B-21.37%47.15%-311.26%
46
Neutral
$1.49B45.38%92.85%
41
Neutral
$1.78B-32.44%-73.94%-31.70%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AUPH
Aurinia Pharmaceuticals
16.37
7.51
84.76%
BCRX
BioCryst
7.10
-0.40
-5.33%
CLDX
Celldex
26.79
-0.65
-2.37%
MNKD
MannKind
5.38
-1.40
-20.65%
SRPT
Sarepta Therapeutics
20.95
-112.39
-84.29%
IMCR
Immunocore Holdings
40.13
7.39
22.57%

Aurinia Pharmaceuticals Corporate Events

Aurinia Pharmaceuticals Reports Strong Q3 2025 Earnings
Nov 5, 2025

Aurinia Pharmaceuticals Inc. is a biopharmaceutical company focused on developing therapies for autoimmune diseases, notably introducing LUPKYNIS, the first FDA-approved oral therapy for lupus nephritis. In its latest earnings report, Aurinia Pharmaceuticals reported a significant increase in net income and product sales for the third quarter of 2025, driven by increased market penetration of LUPKYNIS. The company achieved net product sales of $70.6 million for the quarter, representing a 27% increase compared to the same period in 2024. Operating expenses decreased due to strategic restructuring efforts, leading to a substantial rise in income from operations. Aurinia’s cash position remains strong, with $351.8 million in cash, cash equivalents, and investments as of September 30, 2025, despite significant share repurchases. Looking forward, Aurinia’s management remains optimistic about continued growth and expansion in the autoimmune disease market, supported by ongoing development of new therapies.

Aurinia Pharma’s Earnings Call Highlights Growth and Challenges
Nov 5, 2025

Aurinia Pharmaceuticals’ recent earnings call reflected a generally positive sentiment, underscored by robust sales growth and strong financial performance, particularly for their flagship product, LUPKYNIS. The company also highlighted promising clinical advancements with aritinercept. However, potential challenges loom in the form of regulatory and legal issues.

Business Operations and StrategyFinancial Disclosures
Aurinia Pharmaceuticals Boosts 2025 Sales Guidance Amid Strong Q3 Performance
Positive
Nov 4, 2025

Aurinia Pharmaceuticals reported a significant increase in financial performance for the third quarter of 2025, with total revenue rising by 8% to $73.5 million. Notably, net product sales of LUPKYNIS grew by 27%, prompting the company to raise its sales guidance for 2025 to between $265 million and $270 million. The company also announced progress in advancing Aritinercept toward clinical studies for two autoimmune diseases, indicating a strategic focus on expanding its treatment portfolio.

The most recent analyst rating on (AUPH) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
Aurinia Pharmaceuticals Reports Strong Q3 2025 Growth and Raises Sales Guidance
Positive
Nov 4, 2025

Aurinia Pharmaceuticals reported significant financial growth for the third quarter of 2025, with LUPKYNIS sales increasing by 27% and total revenue reaching $73.5 million, an 8% rise from the previous year. The company has raised its 2025 sales guidance, reflecting strong momentum from updated lupus nephritis treatment guidelines and positive results from a Phase 1 study of aritinercept, which is advancing towards clinical studies in two autoimmune diseases.

The most recent analyst rating on (AUPH) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
Aurinia Pharmaceuticals to Announce Q3 2025 Financial Results and Business Update
Neutral
Nov 3, 2025

Aurinia Pharmaceuticals announced it will report its financial results for the three and nine months ended September 30, 2025, and provide an update on its recent business progress on November 4, 2025. This announcement is significant as it may offer insights into the company’s financial health and strategic direction, potentially impacting its market positioning and stakeholder interests.

The most recent analyst rating on (AUPH) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Aurinia Pharmaceuticals Advances Voclosporin Study in Young Lupus Nephritis Patients
Oct 27, 2025

Study Overview: Aurinia Pharmaceuticals is conducting a study titled An Open-Label Extension Study to Assess the Long-Term Safety and Efficacy of Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis. The study aims to evaluate the long-term safety and tolerability of voclosporin over an additional 12 months in young patients who have completed previous treatment for lupus nephritis. This research is significant as it addresses the need for effective long-term treatment options for this condition in younger populations.

Aurinia Pharmaceuticals Advances Lupus Nephritis Study in Young Patients
Oct 27, 2025

Study Overview: Aurinia Pharmaceuticals is conducting a study titled A Double-Blind, Placebo-Controlled, Dose Escalation Study to Assess the Efficacy, Safety and Pharmacokinetics of Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis. The study aims to evaluate the efficacy and safety of voclosporin in achieving renal response in young patients with active lupus nephritis over 24 weeks, highlighting its potential significance in treating this condition.

Business Operations and StrategyProduct-Related Announcements
Aurinia Pharmaceuticals to Present New LUPKYNIS Data at Key Conferences
Positive
Oct 15, 2025

Aurinia Pharmaceuticals announced that new data on LUPKYNIS (voclosporin) will be presented at the American College of Rheumatology Convergence and the American Society of Nephrology Kidney Week 2025. These presentations, in collaboration with independent investigators, will highlight real-world effectiveness, usage in pediatric patients, and the drug’s distribution and clearance. The findings aim to enhance the medical community’s understanding of voclosporin’s role in treating lupus nephritis, reinforcing Aurinia’s commitment to advancing patient care.

The most recent analyst rating on (AUPH) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Aurinia Pharmaceuticals Reaffirms Confidence in LUPKYNIS After Retraction
Positive
Sep 30, 2025

Aurinia Pharmaceuticals responded to a retracted LinkedIn post by an FDA official regarding voclosporin, affirming the positive benefit/risk profile of its product LUPKYNIS. The drug, approved by the FDA in January 2021 and for long-term use in April 2024, has shown sustained efficacy and safety in clinical studies, reinforcing Aurinia’s position in the autoimmune treatment market.

The most recent analyst rating on (AUPH) stock is a Buy with a $11.00 price target. To see the full list of analyst forecasts on Aurinia Pharmaceuticals stock, see the AUPH Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 25, 2025