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Aurinia Pharmaceuticals (AUPH)
NASDAQ:AUPH
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Aurinia Pharmaceuticals (AUPH) AI Stock Analysis

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AUPH

Aurinia Pharmaceuticals

(NASDAQ:AUPH)

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Outperform 76 (OpenAI - 5.2)
Rating:76Outperform
Price Target:
$17.00
▲(5.92% Upside)
Action:Reiterated
Date:05/12/26
The score is driven primarily by strong improving financial performance (profitability and free cash flow with low leverage) and supportive earnings-call guidance for continued LUPKYNIS growth. Offsetting factors are neutral technical momentum and sustainability risks tied to volatility and one-time tax benefits, with competitive and regulatory uncertainties also tempering the outlook.
Positive Factors
Commercial Growth (LUPKYNIS)
Sustained double‑digit LUPKYNIS revenue growth and explicit 2026 sales guidance indicate durable product-market fit and stable prescription demand. Continued top-line scale supports recurring revenue, distribution relationships, and investment in commercial activities that underpin medium-term cash generation.
Negative Factors
One-time Earnings Boost
Reported profitability in 2025 was materially amplified by a non-recurring tax/valuation allowance benefit, which weakens the signal about underlying operating earnings. This reduces confidence in sustained net income levels and complicates forecasting of long-term free cash flow and return metrics.
Read all positive and negative factors
Positive Factors
Negative Factors
Commercial Growth (LUPKYNIS)
Sustained double‑digit LUPKYNIS revenue growth and explicit 2026 sales guidance indicate durable product-market fit and stable prescription demand. Continued top-line scale supports recurring revenue, distribution relationships, and investment in commercial activities that underpin medium-term cash generation.
Read all positive factors

Aurinia Pharmaceuticals Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Breaks down revenue by different business segments, highlighting which areas are driving growth and profitability. This helps assess the company's strategic focus and potential areas of risk or opportunity.
Chart InsightsAurinia Pharmaceuticals is experiencing robust growth in net product sales, particularly driven by LUPKYNIS, which saw a 27% year-over-year increase, prompting a raised 2025 sales guidance. This momentum is reflected in the steady rise in net product sales over recent quarters. While the License, Collaboration, and Royalty segment shows volatility, the strategic focus on LUPKYNIS and new clinical developments with aritinercept are key growth drivers. However, regulatory and legal challenges could pose risks. The company's strong cash flow and net income growth further underscore its solid financial footing.
Data provided by:The Fly

Aurinia Pharmaceuticals (AUPH) vs. SPDR S&P 500 ETF (SPY)

Aurinia Pharmaceuticals Business Overview & Revenue Model

Company Description
Aurinia Pharmaceuticals Inc., a commercial-stage biopharmaceutical company, focuses on developing and commercializing therapies to treat various diseases with unmet medical need in the United States and internationally. The company offers LUPKYNIS...
How the Company Makes Money
Aurinia primarily makes money by commercializing LUPKYNIS (voclosporin). Its revenue model is largely prescription-driven: when patients are prescribed LUPKYNIS and the product is dispensed through distribution and specialty pharmacy channels, Aur...

Aurinia Pharmaceuticals Earnings Call Summary

Earnings Call Date:Feb 26, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Jul 30, 2026
Earnings Call Sentiment Positive
The call highlights robust commercial momentum for LUPKYNIS with double-digit top-line growth, materially improved cash generation, a strong balance sheet and share repurchases. Management provided constructive 2026 guidance and disclosed promising early clinical results for aritinercept. Offsetting these positives are a significant one-time tax benefit that materially boosted reported net income, termination of a pediatric study (creating regulatory follow-up risk), emerging competition (Gazyva), limited near-term transparency on quarterly performance, and early-stage development uncertainties (ADAs). Overall, the positives—sustained product revenue growth, strong cash flow, and advancing pipeline—outweigh the headwinds, though some risks remain.
Positive Updates
Strong LUPKYNIS Commercial Growth
Net product sales of LUPKYNIS for full year 2025 were $271.3M, up 25% year-over-year from $216.2M. Management reported LUPKYNIS sales grew 25% in 2025 and expects 2026 net product sales of $305M–$315M (up 12%–16% vs. 2025).
Negative Updates
Net Income Heavily Influenced by One-Time Tax Benefit
Q4 2025 net income included an income tax benefit of $175.1M and FY2025 included $173M related to the release of a valuation allowance on deferred tax assets. Management notes this benefit primarily drove the large YoY net income and EPS improvements, indicating part of the profitability gain is non-recurring.
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Q4-2025 Updates
Negative
Strong LUPKYNIS Commercial Growth
Net product sales of LUPKYNIS for full year 2025 were $271.3M, up 25% year-over-year from $216.2M. Management reported LUPKYNIS sales grew 25% in 2025 and expects 2026 net product sales of $305M–$315M (up 12%–16% vs. 2025).
Read all positive updates
Company Guidance
On the call Aurinia provided 2026 guidance of total revenue of $315–$325 million (up 11%–15% vs. 2025) and net product sales of LUPKYNIS of $305–$315 million (up 12%–16% vs. 2025); that outlook is framed by FY‑2025 results of total revenue $283.1M (up 20% vs. $235.1M in 2024, or +26% excluding a $10M 2024 milestone), LUPKYNIS sales $271.3M (up 25% YoY), net income $287.2M (driven in part by a $173M income tax benefit), diluted EPS $2.07, operating cash flow $135.7M (up 206% YoY), cash and investments of $398M, and recent share repurchases of 12.2M shares for $98.2M that reduced fully diluted shares from 149.8M to 139.7M; Q4 highlights included revenue $77.1M, LUPKYNIS sales $74.2M (both +29% YoY), Q4 net income $210.8M (driven by a $175.1M tax benefit), diluted EPS $1.53, and Q4 operating cash flow $45.7M (up 52% YoY).

Aurinia Pharmaceuticals Financial Statement Overview

Summary
Strong step-change in fundamentals: revenue scaled and the company shifted from multi-year losses/cash burn (2021–2023) to strong profitability and robust free cash flow in 2024–TTM 2026, with low leverage. The key offset is high volatility in margins/returns, raising durability questions.
Income Statement
86
Very Positive
Balance Sheet
78
Positive
Cash Flow
84
Very Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue298.30M283.06M235.13M175.51M134.03M45.60M
Gross Profit267.70M250.39M206.88M161.37M128.37M44.51M
EBITDA161.78M127.76M31.73M-63.05M-103.65M-177.44M
Net Income298.21M287.20M5.75M-78.02M-108.18M-180.97M
Balance Sheet
Total Assets724.00M751.59M550.64M548.06M470.86M543.37M
Cash, Cash Equivalents and Short-Term Investments378.78M398.00M358.48M350.49M389.39M466.08M
Total Debt68.64M74.81M79.37M97.61M8.09M8.74M
Total Liabilities156.37M170.26M173.17M170.11M65.42M64.28M
Stockholders Equity567.63M581.33M377.48M377.95M405.44M479.09M
Cash Flow
Free Cash Flow165.55M135.41M44.11M-34.18M-79.82M-159.19M
Operating Cash Flow165.82M135.66M44.39M-33.46M-79.53M-157.69M
Investing Cash Flow-82.01M-32.77M39.26M-6.71M-60.63M-103.87M
Financing Cash Flow-109.08M-106.11M-49.09M-5.13M2.43M221.11M

Aurinia Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price16.05
Price Trends
50DMA
15.52
Negative
100DMA
15.06
Positive
200DMA
14.33
Positive
Market Momentum
MACD
-0.07
Positive
RSI
46.59
Neutral
STOCH
32.19
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AUPH, the sentiment is Negative. The current price of 16.05 is above the 20-day moving average (MA) of 15.59, above the 50-day MA of 15.52, and above the 200-day MA of 14.33, indicating a neutral trend. The MACD of -0.07 indicates Positive momentum. The RSI at 46.59 is Neutral, neither overbought nor oversold. The STOCH value of 32.19 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AUPH.

Aurinia Pharmaceuticals Risk Analysis

Aurinia Pharmaceuticals disclosed 33 risk factors in its most recent earnings report. Aurinia Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aurinia Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$1.98B6.8364.48%20.62%696.05%
61
Neutral
$2.12B-4.41123.57%75.92%-569.22%
61
Neutral
$1.50B-79.71-4.83%23.64%-29.23%
58
Neutral
$1.72B26.224.89%-2.20%77.51%
57
Neutral
$1.06B-44.2145.59%21.23%-174.19%
52
Neutral
$2.27B-6.78-50.72%-88.54%-58.13%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AUPH
Aurinia Pharmaceuticals
15.39
7.39
92.38%
BCRX
BioCryst
8.34
-2.85
-25.47%
CLDX
Celldex
28.90
9.03
45.45%
MNKD
MannKind
3.43
-0.99
-22.40%
SRPT
Sarepta Therapeutics
16.25
-22.62
-58.19%
IMCR
Immunocore Holdings
29.56
-9.08
-23.50%

Aurinia Pharmaceuticals Corporate Events

Business Operations and StrategyM&A Transactions
Aurinia Pharmaceuticals Completes Acquisition of Kezar Life Sciences
Positive
May 11, 2026
On May 8, 2026, Aurinia Pharma U.S., Inc. completed a tender offer to acquire approximately 80.24% of Kezar Life Sciences’ outstanding common stock for $6.955 in cash per share plus one contingent value right, following a merger agreement si...
Business Operations and StrategyM&A Transactions
Aurinia Pharmaceuticals to Acquire Kezar, Expanding Autoimmune Pipeline
Positive
Apr 3, 2026
On March 30, 2026, Aurinia Pharma U.S., Inc. agreed to acquire Kezar Life Sciences via a tender offer at $6.955 in cash per share plus a non‑transferable contingent value right. The CVR will entitle Kezar shareholders to potential additional...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 12, 2026