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Celldex Therapeutics (CLDX)
NASDAQ:CLDX
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Celldex (CLDX) AI Stock Analysis

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CLDX

Celldex

(NASDAQ:CLDX)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
$40.00
▲(15.77% Upside)
Action:Reiterated
Date:06/27/26
The score is held back primarily by weak financial performance (sharp revenue decline, large losses, and substantial cash burn). Offsetting this, technicals are notably positive with the stock trading above major moving averages and positive MACD. Valuation remains constrained by losses (negative P/E), while recent corporate actions improve liquidity but introduce dilution risk.
Positive Factors
Low leverage
Very low debt-to-equity (~0.4%) materially reduces refinancing and interest rate risk for a cash-burning biotech. This structural balance-sheet strength preserves optionality to fund trials, pursue partnerships, or bridge setbacks without immediate solvency stress, supporting multi‑month operations.
Negative Factors
High cash burn
Sustained operating and free cash flow deficits (roughly -$222M to -$224M TTM) create persistent funding needs. Over months this forces reliance on external financing or partnerships, raising dilution risk and potentially constraining program timelines if capital access tightens.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage
Very low debt-to-equity (~0.4%) materially reduces refinancing and interest rate risk for a cash-burning biotech. This structural balance-sheet strength preserves optionality to fund trials, pursue partnerships, or bridge setbacks without immediate solvency stress, supporting multi‑month operations.
Read all positive factors

Celldex (CLDX) vs. SPDR S&P 500 ETF (SPY)

Celldex Business Overview & Revenue Model

Company Description
Celldex Therapeutics, Inc. is a biopharmaceutical company dedicated to developing antibody-based treatments, specifically monoclonal and bispecific antibodies, for a range of diseases. Their pipeline features therapeutic candidates aimed at both i...
How the Company Makes Money
Celldex is a clinical-stage biotechnology company and, as such, it typically does not generate recurring revenue from marketed products. Its earnings potential and reported revenue, when present, generally come from (a) collaboration and licensing...

Celldex Financial Statement Overview

Summary
Overall fundamentals are weak: revenue is small and declining (TTM down ~45%), profitability is deeply negative (net margin ~-346%), and cash burn is heavy with negative operating and free cash flow (about -$222M and -$224M TTM). The main offset is a comparatively strong balance sheet with very low leverage (debt-to-equity ~0.4%), which provides flexibility despite continued losses and negative ROE (~-51%).
Income Statement
18
Very Negative
Balance Sheet
63
Positive
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue820.00K1.50M7.02M6.88M2.36M4.65M
Gross Profit-117.16M1.50M-156.53M-111.13M-79.90M-48.66M
EBITDA-280.32M-255.42M-154.69M-139.03M-104.20M-66.08M
Net Income-283.69M-258.80M-157.86M-141.43M-112.33M-70.51M
Balance Sheet
Total Assets511.25M582.98M792.34M465.63M352.74M444.65M
Cash, Cash Equivalents and Short-Term Investments451.46M518.57M725.28M421.70M304.95M408.25M
Total Debt1.91M2.34M3.81M2.54M4.03M3.04M
Total Liabilities55.03M55.82M45.34M36.46M26.53M25.18M
Stockholders Equity456.23M527.16M747.00M429.17M326.20M419.48M
Cash Flow
Free Cash Flow-225.96M-213.66M-159.70M-109.11M-105.56M-62.16M
Operating Cash Flow-222.16M-210.94M-157.78M-107.29M-103.73M-60.91M
Investing Cash Flow238.24M209.07M-290.13M-105.78M89.94M-216.16M
Financing Cash Flow2.51M2.39M441.45M218.46M4.08M272.37M

Celldex Technical Analysis

Technical Analysis Sentiment
Positive
Last Price34.55
Price Trends
50DMA
33.25
Positive
100DMA
32.18
Positive
200DMA
29.07
Positive
Market Momentum
MACD
1.84
Negative
RSI
64.62
Neutral
STOCH
52.40
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLDX, the sentiment is Positive. The current price of 34.55 is below the 20-day moving average (MA) of 36.35, above the 50-day MA of 33.25, and above the 200-day MA of 29.07, indicating a bullish trend. The MACD of 1.84 indicates Negative momentum. The RSI at 64.62 is Neutral, neither overbought nor oversold. The STOCH value of 52.40 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CLDX.

Celldex Risk Analysis

Celldex disclosed 2 risk factors in its most recent earnings report. Celldex reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Celldex Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$5.31B-26.79%96.03%82.27%
59
Neutral
$3.10B-7.67-74.86%-85.06%
56
Neutral
$3.00B-8.97-50.72%-88.54%-58.13%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$2.11B-5.48-60.70%23382.78%7.01%
49
Neutral
$962.33M-8.71-11.85%47.10%-35.51%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CLDX
Celldex
38.31
15.34
66.78%
TVTX
Travere Therapeutics
56.74
40.23
243.67%
VRDN
Viridian Therapeutics
19.06
2.01
11.79%
VERA
Vera Therapeutics
42.50
18.74
78.87%
JANX
Janux Therapeutics Inc
16.03
-11.72
-42.23%

Celldex Corporate Events

Business Operations and StrategyShareholder Meetings
Celldex Shareholders Approve Expanded Equity Incentive Plan
Positive
Jun 26, 2026
At its June 25, 2026 annual meeting, Celldex Therapeutics stockholders approved an amendment to the company’s 2021 Omnibus Equity Incentive Plan, increasing the shares available for issuance by 3,400,000 to a total of 12,900,000 and clarifyi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 27, 2026