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10x Genomics Inc (TXG)
NASDAQ:TXG

10x Genomics (TXG) AI Stock Analysis

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10x Genomics

(NASDAQ:TXG)

Rating:61Neutral
Price Target:
$11.00
▲(1.20%Upside)
10x Genomics' strong financial stability and technical momentum are tempered by critical challenges in profitability and valuation. The mixed earnings outlook, coupled with strategic cost reductions, highlights both the potential and risks in the current macroeconomic climate.
Positive Factors
Litigation and Settlements
The global IP settlement with BRKR/NanoString resolves all outstanding litigation, shoring up the balance sheet via $68M plus ongoing royalties.
Product Utilization
Consumables revenue was ahead of expectations, driven by broader Xenium utilization.
Revenue Performance
Service revenue increased by 47% year-over-year, outperforming market expectations.
Negative Factors
Financial Guidance
Annual guidance was withdrawn due to limited visibility in the US academic and government end market.
Market Uncertainty
Instrument placements decreased significantly due to funding concerns in the US academic and government markets.
Revenue Challenges
TXG faces significant pressure from the US academic end-market, which accounts for 40-50% of TXG revenue.

10x Genomics (TXG) vs. SPDR S&P 500 ETF (SPY)

10x Genomics Business Overview & Revenue Model

Company Description10x Genomics (TXG) is a biotechnology company specializing in the development of innovative solutions for genetic analysis. Founded in 2012 and headquartered in Pleasanton, California, the company operates in the life sciences sector, focusing on genomic sequencing technologies. Its core products include instruments, consumables, and software that enable researchers to conduct high-resolution single-cell and spatial analysis to gain deeper insights into complex biological systems.
How the Company Makes Money10x Genomics generates revenue through the sale of its proprietary instruments, consumables, and software to research institutions, pharmaceutical companies, and other entities engaged in life sciences research. The company offers a portfolio of products such as the Chromium Single Cell Platform, Visium Spatial Gene Expression, and software tools that facilitate data analysis and interpretation. Consumables, which are required for each experiment, represent a significant and recurring revenue stream for the company. Additionally, 10x Genomics may engage in strategic partnerships and collaborations that can provide supplementary revenue and enhance their market presence.

10x Genomics Key Performance Indicators (KPIs)

Any
Any
Instruments Revenue by Type
Instruments Revenue by Type
Shows revenue generated from different types of instruments, highlighting which products are driving sales and indicating the company's focus areas in technology and innovation.
Chart Insights10x Genomics' Chromium Instruments revenue is declining, reflecting broader challenges in the market, including reduced NIH funding and lower reaction prices. In contrast, Spatial Instruments have shown strong growth, driven by successful product launches like Visium HD and Xenium Prime 5K. However, recent quarters indicate a slowdown, aligning with a 51% drop in spatial instrument revenue in Q4 2024. Despite these challenges, the company remains committed to innovation and expects double-digit growth in spatial revenue in 2025, although NIH funding uncertainties pose a risk.
Data provided by:Main Street Data

10x Genomics Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q1-2025)
|
% Change Since: 25.96%|
Next Earnings Date:Jul 31, 2025
Earnings Call Sentiment Neutral
The earnings call presented a mixed outlook. While there were significant achievements in consumables growth, particularly in APAC, and promising product developments, these were overshadowed by declines in instrument revenue and substantial uncertainties in the U.S. research funding environment. The company's decision to withdraw full-year guidance reflects this uncertainty.
Q1-2025 Updates
Positive Updates
Strong Consumables Revenue Growth
Total consumables revenue increased 5% year-over-year to $115.4 million, with spatial consumables revenue up 18%, driven by Xenium consumables.
Robust Demand in APAC
Revenue in the APAC region increased by 22%, with strong consumable sales offsetting declines in other areas.
Cost Reduction Measures
The company implemented cost-saving measures, including an 8% reduction in global workforce and significant reductions in non-headcount expenses, expected to reduce 2025 operating expenses by more than $50 million compared to 2024.
Positive Developments in Product Usage
Chromium reaction volumes showed robust year-over-year growth, and Xenium consumable revenue and volume continued to grow strongly.
Innovative Product Launches
Recent product launches, including GEM-X technology and Visium HD, continue to resonate with customers and advance the company's leadership in single-cell and spatial biology.
Negative Updates
Decline in Instrument Revenue
Total instrument revenue decreased by 42% year-over-year, with Chromium instrument revenue down 25% and spatial instrument revenue down 49%.
U.S. Academic and Government Funding Pressures
Significant uncertainty in U.S. academic and government research funding, leading to unpredictable customer purchasing behavior and reduced visibility on outlook.
Withdrawal of Full-Year Revenue Guidance
The company withdrew its full-year revenue guidance due to uncertainties in the funding environment, providing only Q2 guidance instead.
Challenges in EMEA Revenue
Revenue in the EMEA region decreased by 8%, attributed to challenging macroeconomic conditions affecting instrument sales.
Company Guidance
During the first quarter of 2025, 10x Genomics reported total revenue of $155 million, including a $26 million gain from a settlement with Vizgen. Excluding this, revenue was $138 million, down 2% year-over-year. Consumables revenue grew by 5% to $115.4 million, with spatial consumables up 18%, while instrument revenue declined by 42% to $14.8 million. The company cited a challenging macro environment, especially within U.S. academic and government funding, as a significant factor affecting revenue, leading to the withdrawal of its full-year guidance. Approximately 40-50% of 10x Genomics' revenue is exposed to these funding sources. Gross profit for the quarter was $105.4 million with a margin of 68%, and operating expenses decreased to $144.8 million. The company ended the quarter with $427 million in cash and securities. Due to uncertainties, 10x Genomics implemented cost-cutting measures, including an 8% workforce reduction, anticipating a $50 million reduction in operating expenses for 2025. For the second quarter, revenue is expected to be between $138 million and $142 million. Despite the challenges, the company remains confident in the long-term growth potential of its products and market position.

10x Genomics Financial Statement Overview

Summary
10x Genomics shows strong gross margins and a robust equity structure, indicating financial stability. However, ongoing net losses and negative profit margins present significant profitability challenges, despite improvements in cash flow management.
Income Statement
65
Positive
The company exhibits a strong gross profit margin of around 68.8% TTM, indicating efficient cost management relative to revenue. However, the net profit margin is negative, reflecting ongoing losses due to high operating expenses. Revenue growth has been modest at 2.3% TTM, and the negative EBIT and EBITDA margins highlight profitability challenges.
Balance Sheet
72
Positive
The balance sheet shows a strong equity position with an equity ratio of 78.2% TTM, signifying financial stability. The debt-to-equity ratio is low at 0.11, indicating low leverage. However, the return on equity is negative, reflecting consistent net losses which impact shareholder returns.
Cash Flow
58
Neutral
The company has shown improvement in free cash flow, turning positive to $44.36M TTM from previous losses. The operating cash flow to net income ratio is negative, reflecting operational challenges. However, the free cash flow growth rate is notable, indicating better cash management.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
624.66M610.78M618.73M516.41M490.49M298.85M
Gross Profit
429.69M414.48M409.31M396.02M416.40M240.38M
EBIT
-172.39M-194.56M-194.95M-167.94M-52.91M-85.32M
EBITDA
-127.01M-133.99M-205.11M-128.49M-24.59M-513.77M
Net Income Common Stockholders
-157.04M-182.63M-255.10M-166.00M-58.22M-542.73M
Balance SheetCash, Cash Equivalents and Short-Term Investments
426.90M393.40M388.69M429.98M587.45M663.60M
Total Assets
903.39M918.64M965.14M1.03B1.02B929.34M
Total Debt
80.07M82.61M95.37M95.18M81.98M62.98M
Net Debt
-296.99M-261.45M-263.91M-124.57M-505.47M-600.63M
Total Liabilities
196.50M208.50M224.10M223.24M201.26M190.27M
Stockholders Equity
706.89M710.13M741.04M805.74M817.57M739.07M
Cash FlowFree Cash Flow
44.36M-5.73M-64.72M-165.27M-122.65M-256.29M
Operating Cash Flow
56.74M6.66M-15.20M-33.61M-21.37M-217.90M
Investing Cash Flow
-45.16M-32.63M133.49M-350.89M-106.73M-38.39M
Financing Cash Flow
9.70M10.91M13.67M15.82M35.30M468.91M

10x Genomics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.87
Price Trends
50DMA
8.91
Positive
100DMA
10.11
Positive
200DMA
13.61
Negative
Market Momentum
MACD
0.52
Negative
RSI
63.19
Neutral
STOCH
82.97
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TXG, the sentiment is Positive. The current price of 10.87 is above the 20-day moving average (MA) of 9.64, above the 50-day MA of 8.91, and below the 200-day MA of 13.61, indicating a neutral trend. The MACD of 0.52 indicates Negative momentum. The RSI at 63.19 is Neutral, neither overbought nor oversold. The STOCH value of 82.97 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for TXG.

10x Genomics Risk Analysis

10x Genomics disclosed 70 risk factors in its most recent earnings report. 10x Genomics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

10x Genomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
$1.75B-0.25%9.37%95.72%
TXTXG
61
Neutral
$1.37B-22.03%-0.13%42.17%
61
Neutral
$270.05M-19.80%4.88%37.87%
WGWGS
60
Neutral
$1.91B38.75-16.61%48.81%72.54%
59
Neutral
$1.53B-43.33%22.29%-32.89%
56
Neutral
$195.15M-60.75%4.66%11.33%
54
Neutral
$5.25B3.27-44.35%6.27%16.79%-0.10%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TXG
10x Genomics
10.87
-9.09
-45.54%
HCAT
Health Catalyst
3.65
-2.39
-39.57%
SDGR
Schrodinger
21.05
2.10
11.08%
CERT
Certara
10.57
-2.90
-21.53%
WGS
GeneDx Holdings
64.43
37.53
139.52%
SOPH
SOPHiA GENETICS
3.04
-1.66
-35.32%

10x Genomics Corporate Events

Executive/Board ChangesShareholder Meetings
10x Genomics Elects Directors at Annual Meeting
Neutral
Jun 5, 2025

On June 3, 2025, 10x Genomics held its annual stockholders’ meeting via webcast, with a quorum of approximately 87.7% of eligible votes. The meeting resulted in the election of two Class III directors for a three-year term and the ratification of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025.

The most recent analyst rating on (TXG) stock is a Buy with a $18.00 price target. To see the full list of analyst forecasts on 10x Genomics stock, see the TXG Stock Forecast page.

Legal Proceedings
10x Genomics Settles Litigation with Bruker Corporation
Neutral
May 14, 2025

On May 12, 2025, 10x Genomics, Inc. reached a settlement and licensing agreement with Bruker Corporation, resolving all global litigation and proceedings between the parties. This agreement follows a series of lawsuits initiated by 10x Genomics against NanoString Technologies, Inc., which were inherited by Bruker after acquiring certain NanoString assets in May 2024, and is expected to lead to the dismissal of all claims within five days of the agreement date.

The most recent analyst rating on (TXG) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on 10x Genomics stock, see the TXG Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
10x Genomics Announces Workforce Reduction to Cut Costs
Negative
May 8, 2025

On May 6, 2025, 10x Genomics announced a reduction in its global workforce by approximately 8% to decrease costs and align with strategic priorities, estimating related expenses between $5.5 million and $6.5 million. The company reported first-quarter 2025 revenue of $154.9 million, a 10% increase from the previous year, driven by a patent litigation settlement. Despite a decrease in instrument revenue, 10x Genomics plans to reduce operating expenses by over $50 million in 2025 and has unveiled new product launches and a partnership with Arc Institute to enhance its market position.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.