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10x Genomics Inc (TXG)
NASDAQ:TXG
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10x Genomics (TXG) AI Stock Analysis

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TXG

10x Genomics

(NASDAQ:TXG)

Rating:56Neutral
Price Target:
$14.00
▼(-0.21% Downside)
10x Genomics' stock score is primarily influenced by its financial performance and technical analysis. While the company shows potential with improving cash flow and positive market momentum, profitability challenges and a negative P/E ratio weigh heavily on its valuation. The technical indicators suggest potential for price appreciation, but the financial fundamentals and valuation concerns limit the overall score.
Positive Factors
Acquisition Strategy
The acquisition of Scale Biosciences strengthens 10x Genomics' leadership position in single cell technology.
Financial Performance
TXG reported revenue that was modestly ahead of expectations, aided by a pull-forward in China.
Product Adoption
Growing placements of Chromium and Single Cell reaction growth on strong adoption of recently launched products plus robust Spatial consumables growth are encouraging signs amidst challenging market environment.
Negative Factors
Guidance Withdrawal
10x Genomics withdrew its full-year guidance due to uncertain macroeconomic conditions and significant exposure to pressured end-markets.
Macroeconomic Challenges
The macro environment remains challenging with external headwinds affecting the biopharma end-market and causing uncertainty in purchasing tools for discovery research.
Revenue Challenges
A significant portion of TXG's revenue comes from the US academic market, which faces budget constraints affecting overall demand.

10x Genomics (TXG) vs. SPDR S&P 500 ETF (SPY)

10x Genomics Business Overview & Revenue Model

Company Description10x Genomics (TXG) is a biotechnology company specializing in genomic sequencing and analysis technologies that enable researchers to gain insights into complex biological systems. Founded in 2012 and headquartered in Pleasanton, California, the company operates primarily in the life sciences sector. Its core products include the Chromium System, which allows for high-throughput single-cell sequencing, and various reagents and software solutions designed for applications in genomics, transcriptomics, and epigenomics. 10x Genomics serves a diverse customer base including academic institutions, pharmaceutical companies, and biotechnology firms, facilitating advancements in precision medicine and personalized therapeutics.
How the Company Makes Money10x Genomics generates revenue primarily through the sale of its genomic sequencing systems, consumables, and related software products. The company's revenue model is based on a combination of product sales and recurring revenue from consumables, which are used in conjunction with its systems. Key revenue streams include sales of the Chromium System, various reagents, and software licenses that support data analysis and interpretation. Additionally, 10x Genomics benefits from strategic partnerships with research institutions and pharmaceutical companies, enhancing its market reach and driving sales through collaborative research initiatives. The increasing demand for genomic research and personalized medicine further contributes to its earnings, as more organizations invest in advanced genomic technologies.

10x Genomics Key Performance Indicators (KPIs)

Any
Any
Instruments Revenue by Type
Instruments Revenue by Type
Shows revenue generated from different types of instruments, highlighting which products are driving sales and indicating the company's focus areas in technology and innovation.
Chart Insights10x Genomics' Chromium Instruments revenue is declining, reflecting broader challenges in the market, including reduced NIH funding and lower reaction prices. In contrast, Spatial Instruments have shown strong growth, driven by successful product launches like Visium HD and Xenium Prime 5K. However, recent quarters indicate a slowdown, aligning with a 51% drop in spatial instrument revenue in Q4 2024. Despite these challenges, the company remains committed to innovation and expects double-digit growth in spatial revenue in 2025, although NIH funding uncertainties pose a risk.
Data provided by:Main Street Data

10x Genomics Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: 9.61%|
Next Earnings Date:Oct 29, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted a mix of positive developments, such as a favorable litigation settlement and growth in spatial consumables, alongside challenges like declining instrument revenue and a difficult funding environment. While there are areas of growth and strategic advancements, the ongoing challenges in the academic and CapEx environment present significant hurdles.
Q2-2025 Updates
Positive Updates
Favorable Patent Litigation Settlement
10x Genomics settled worldwide patent litigation with Bruker on favorable terms, receiving an upfront payment of $68 million, contributing to both operating expenses and license and royalty revenue.
Strong Performance in China
There was a 41% year-over-year increase in APAC revenue, driven by strong performance in China, which benefited from a temporary pull forward in purchasing activity.
Growth in Spatial Consumables Revenue
Spatial consumables revenue increased by 24%, primarily driven by Xenium consumables performance.
Financial Stability and Cash Increase
10x Genomics increased its cash balance by $40 million during the quarter, excluding settlement-related payments.
New Product Launches
Launch of Visium HD 3 Prime and HD cell segmentation capabilities, with upcoming products like Visium HD XL and Xenium RNA plus protein expected to enhance spatial analysis.
Negative Updates
Decline in Chromium Consumables Revenue
Chromium consumables revenue declined by 9%, primarily due to lower average reaction prices.
Significant Decrease in Instrument Revenue
Total instrument revenue decreased by 39%, with Chromium instrument revenue down 35% and spatial instrument revenue down 42%.
Challenging Academic Funding Environment
The academic funding landscape remains uncertain with weaker grant disbursements and extended project timelines affecting customer spending.
U.S. Revenue Decline
Americas revenue was down 15% year-over-year, despite a 7% sequential increase.
Ongoing CapEx Constraints
Customers are facing increased scrutiny on purchases and longer approval timelines, leading to delays in project starts and heightened price sensitivity.
Company Guidance
During the 10x Genomics Second Quarter 2025 Earnings Conference Call, the company reported a total revenue of $173 million for the quarter, with a notable $68 million recognized upfront from settling worldwide patent litigation with Bruker, which contributed to both operating expenses and license and royalty revenue. Excluding this settlement, revenue was $146 million. The company increased its cash balance by $40 million, not including settlement-related payments. The academic funding landscape remains challenging, with cautious customer spending due to shifting policies and weaker grant disbursements. Despite this, signs of robust underlying demand for single-cell solutions were noted, with Chromium reaction volumes growing year-over-year and sequentially. The company achieved a gross margin of 72%, which included the settlement impact, while operating expenses decreased to $95 million. The acquisition of Scale Biosciences was highlighted as a strategic move to enhance capabilities and broaden access to single-cell analysis. Looking forward, 10x Genomics expects third-quarter revenue to range between $140 million and $144 million, taking into account a $4 million revenue pull-forward in China.

10x Genomics Financial Statement Overview

Summary
10x Genomics demonstrates strong gross margins and a solid equity structure, reflecting operational efficiency and financial stability. However, consistent net losses and negative profit margins highlight profitability challenges. The cash flow position has improved, signaling better cash management, but operational risks persist due to negative earnings.
Income Statement
65
Positive
The company exhibits a strong gross profit margin of around 68.8% TTM, indicating efficient cost management relative to revenue. However, the net profit margin is negative, reflecting ongoing losses due to high operating expenses. Revenue growth has been modest at 2.3% TTM, and the negative EBIT and EBITDA margins highlight profitability challenges.
Balance Sheet
72
Positive
The balance sheet shows a strong equity position with an equity ratio of 78.2% TTM, signifying financial stability. The debt-to-equity ratio is low at 0.11, indicating low leverage. However, the return on equity is negative, reflecting consistent net losses which impact shareholder returns.
Cash Flow
58
Neutral
The company has shown improvement in free cash flow, turning positive to $44.36M TTM from previous losses. The operating cash flow to net income ratio is negative, reflecting operational challenges. However, the free cash flow growth rate is notable, indicating better cash management.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue644.47M610.78M618.73M516.41M490.49M298.85M
Gross Profit447.88M414.48M409.31M396.02M416.40M240.38M
EBITDA-54.18M-133.99M-205.11M-128.49M-24.59M-513.77M
Net Income-84.60M-182.63M-255.10M-166.00M-58.22M-542.73M
Balance Sheet
Total Assets979.97M918.64M965.14M1.03B1.02B929.34M
Cash, Cash Equivalents and Short-Term Investments447.26M393.40M388.69M429.98M587.45M663.60M
Total Debt86.74M82.61M95.37M95.18M81.98M62.98M
Total Liabilities206.69M208.50M224.10M223.24M201.26M190.27M
Stockholders Equity773.28M710.13M741.04M805.74M817.57M739.07M
Cash Flow
Free Cash Flow56.88M-5.73M-64.72M-165.27M-122.65M-256.29M
Operating Cash Flow66.95M6.66M-15.20M-33.61M-21.37M-217.90M
Investing Cash Flow-58.04M-32.63M133.49M-350.89M-106.73M-38.39M
Financing Cash Flow8.62M10.91M13.67M15.82M35.30M468.91M

10x Genomics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price14.03
Price Trends
50DMA
12.68
Positive
100DMA
10.70
Positive
200DMA
12.05
Positive
Market Momentum
MACD
0.34
Negative
RSI
59.14
Neutral
STOCH
88.51
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TXG, the sentiment is Positive. The current price of 14.03 is above the 20-day moving average (MA) of 13.31, above the 50-day MA of 12.68, and above the 200-day MA of 12.05, indicating a bullish trend. The MACD of 0.34 indicates Negative momentum. The RSI at 59.14 is Neutral, neither overbought nor oversold. The STOCH value of 88.51 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for TXG.

10x Genomics Risk Analysis

10x Genomics disclosed 71 risk factors in its most recent earnings report. 10x Genomics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

10x Genomics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
$3.50B6,517.110.60%48.70%
65
Neutral
$1.75B220.040.76%11.61%
56
Neutral
$1.75B-11.30%2.02%65.33%
52
Neutral
$228.42M-74.09%7.31%-7.49%
51
Neutral
$7.83B-0.15-40.10%2.29%21.46%-2.01%
50
Neutral
$1.44B-44.40%18.59%10.96%
46
Neutral
$235.05M-28.42%5.55%-0.99%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TXG
10x Genomics
14.03
-8.26
-37.06%
HCAT
Health Catalyst
3.50
-3.32
-48.68%
SDGR
Schrodinger
19.64
-0.82
-4.01%
CERT
Certara
10.87
-1.60
-12.83%
WGS
GeneDx Holdings
126.25
94.56
298.39%
SOPH
SOPHiA GENETICS
3.38
-0.42
-11.05%

10x Genomics Corporate Events

Executive/Board ChangesShareholder Meetings
10x Genomics Elects Directors at Annual Meeting
Neutral
Jun 5, 2025

On June 3, 2025, 10x Genomics held its annual stockholders’ meeting via webcast, with a quorum of approximately 87.7% of eligible votes. The meeting resulted in the election of two Class III directors for a three-year term and the ratification of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025.

The most recent analyst rating on (TXG) stock is a Buy with a $18.00 price target. To see the full list of analyst forecasts on 10x Genomics stock, see the TXG Stock Forecast page.

Legal Proceedings
10x Genomics Settles Litigation with Bruker Corporation
Neutral
May 14, 2025

On May 12, 2025, 10x Genomics, Inc. reached a settlement and licensing agreement with Bruker Corporation, resolving all global litigation and proceedings between the parties. This agreement follows a series of lawsuits initiated by 10x Genomics against NanoString Technologies, Inc., which were inherited by Bruker after acquiring certain NanoString assets in May 2024, and is expected to lead to the dismissal of all claims within five days of the agreement date.

The most recent analyst rating on (TXG) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on 10x Genomics stock, see the TXG Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 14, 2025