Revenue Growth (Excluding Prior-Year Settlement)
Q1 revenue was $150.8M, up 9% year-over-year when excluding nonrecurring settlement revenue from the prior-year period.
Strong Consumables Performance
Total consumables revenue grew 13% year-over-year; single cell consumables were up 6% (driven by double-digit growth in reaction volumes from FLEX and FLEX Apex) and spatial consumables grew 31%, driven by Xenium momentum.
Gross Margin Improvement
Gross margin improved to 70% in Q1 2026 from 68% in the prior-year period, primarily driven by lower warranty costs and lower inventory write-downs.
Operating Expense Reductions and Improved Cash Position
Total operating expenses decreased 15% year-over-year (20% lower excluding the prior-year one-time settlement gain); company ended the quarter with $540M in cash, cash equivalents, and marketable securities—up $113M year-over-year and up $16M sequentially.
Atara Launch — Major Product Introduction
Launched Atara, described as the company's most significant product introduction: enables spatial whole-transcriptome analysis with single-cell sensitivity at scale, processes up to 800 whole-transcriptome 1cm2 samples per instrument per year (over 3,000 with targeted Atara Select panels), uses standard glass slides, on-board GPU image processing, and a long-term upgradable roadmap (automation, protein multiomics, in situ sequencing, 10x Cloud enhancements). Early customer response and preorders described as extraordinary.
Partnerships and AI Tailwind
Notable partnerships and initiatives (Chan Zuckerberg Initiative Building Cell Project, Arc Institute Virtual Cell Challenge, Zira Therapeutics perturbation dataset, Biooptimus ‘Stella’ initiative, Chan Zuckerberg Biohub $100M virtual biology initiative) reinforcing demand for large-scale, high-quality biological data and positioning 10x as key data generator for AI-driven biology.
Product Leadership and Translational Momentum
FLEX Apex cited as a game changer for large translational studies (FFPE compatibility, streamlined workflows, cost profile for large cohorts); Xenium driving spatial consumable growth and enabling translational and clinical cohort work.
Maintained Full-Year Outlook
Company maintained full-year 2026 revenue guidance of $600M to $625M, which (excluding 2025 settlement revenue) implies approximately 0% to 4% growth year-over-year and incorporates Atara launch dynamics.