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Tempest Therapeutics (TPST)
NASDAQ:TPST
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Tempest Therapeutics (TPST) AI Stock Analysis

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TPST

Tempest Therapeutics

(NASDAQ:TPST)

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Neutral 43 (OpenAI - Gpt-5.6Sol)
Rating:43Neutral
Price Target:
$1.00
▲(8.70% Upside)
Action:Reiterated
Date:08/19/26
The score is held down primarily by very weak financial performance (no revenue, large losses, cash burn, and negative equity), which raises ongoing funding and dilution risk. Technicals show only modest near-term stabilization while the longer-term trend remains down. Corporate events are mixed—improved access to capital and partnership progress are tempered by Nasdaq listing/governance concerns and continued dilution-related actions—while valuation offers limited support due to negative earnings and no dividend.
Positive Factors
Flexible funding access
The equity facility gives Tempest discretion to draw capital over time rather than raise the full amount at once. This improves financing flexibility for clinical development, although access remains dependent on market and regulatory conditions.
Negative Factors
Pre-revenue operating model
Tempest has no commercial revenue base to offset research and development costs, leaving value dependent on clinical progress, partnering, or eventual product launches. Persistent losses make profitability highly uncertain over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Flexible funding access
The equity facility gives Tempest discretion to draw capital over time rather than raise the full amount at once. This improves financing flexibility for clinical development, although access remains dependent on market and regulatory conditions.
Read all positive factors

Tempest Therapeutics (TPST) vs. SPDR S&P 500 ETF (SPY)

Tempest Therapeutics Business Overview & Revenue Model

Company Description
Tempest Therapeutics Inc. is an oncology company, currently in the clinical development phase, dedicated to advancing novel small molecule drugs designed to combat cancer. The firm's pipeline highlights two key therapeutic candidates: TPST-1495, a...
How the Company Makes Money
Tempest Therapeutics is a clinical-stage biotech and does not primarily operate a mature product-sales business. Its cash generation typically comes from (a) collaboration and licensing arrangements (e.g., upfront payments, research funding or cos...

Tempest Therapeutics Financial Statement Overview

Summary
Very weak fundamentals consistent with an early-stage biotech: $0 revenue, persistent large net losses (TTM net loss -$40.5M), and ongoing cash burn (TTM operating cash flow -$20.7M). Balance-sheet risk is elevated because stockholders’ equity turned negative in TTM (-$1.1M), increasing financing and dilution risk despite reduced debt (~$7.6M TTM).
Income Statement
12
Very Negative
Balance Sheet
18
Very Negative
Cash Flow
20
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-22.18M0.00-389.00K0.000.000.00
EBITDA-40.29M-25.79M-40.14M-27.66M-33.45M-26.65M
Net Income-40.47M-26.26M-41.84M-29.49M-35.71M-28.30M
Balance Sheet
Total Assets9.63M16.93M41.49M51.60M46.09M73.24M
Cash, Cash Equivalents and Short-Term Investments779.00K7.71M30.27M39.23M31.23M51.83M
Total Debt7.56M8.14M15.37M20.66M22.11M18.54M
Total Liabilities10.72M10.26M22.36M24.84M27.98M37.12M
Stockholders Equity-1.09M6.67M19.13M26.77M18.11M36.12M
Cash Flow
Free Cash Flow-20.73M-26.82M-33.46M-27.53M-31.63M-26.09M
Operating Cash Flow-20.73M-26.82M-33.03M-27.36M-31.07M-25.96M
Investing Cash Flow0.000.00-435.00K-170.00K-562.00K-97.00K
Financing Cash Flow7.23M4.26M24.50M35.60M11.40M59.06M

Tempest Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.92
Price Trends
50DMA
1.05
Negative
100DMA
1.41
Negative
200DMA
2.41
Negative
Market Momentum
MACD
0.01
Negative
RSI
50.19
Neutral
STOCH
29.66
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TPST, the sentiment is Negative. The current price of 0.92 is below the 20-day moving average (MA) of 0.99, below the 50-day MA of 1.05, and below the 200-day MA of 2.41, indicating a neutral trend. The MACD of 0.01 indicates Negative momentum. The RSI at 50.19 is Neutral, neither overbought nor oversold. The STOCH value of 29.66 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TPST.

Tempest Therapeutics Risk Analysis

Tempest Therapeutics disclosed 79 risk factors in its most recent earnings report. Tempest Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Tempest Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$34.59M3.0683.42%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$29.91M-1.44-456.35%9.68%
45
Neutral
$12.23M-0.34-346.03%30.16%
44
Neutral
$19.56M-0.424092.98%15.37%
43
Neutral
$16.62M-0.23-729.89%69.34%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TPST
Tempest Therapeutics
1.04
-9.53
-90.16%
ATNM
Actinium Pharmaceuticals
1.10
-0.69
-38.55%
PDSB
PDS Biotechnology
0.22
-1.08
-83.23%
LTRN
Lantern Pharma
2.34
-2.23
-48.80%
CALC
CalciMedica
0.57
-2.22
-79.50%

Tempest Therapeutics Corporate Events

Business Operations and StrategyShareholder Meetings
Tempest Therapeutics Adjourns Special Stockholder Meeting Again
Negative
Aug 18, 2026
On August 17, 2026, Tempest Therapeutics reconvened a special meeting of stockholders originally convened and adjourned on July 27, 2026, to seek approval of an amendment to its Restated Certificate of Incorporation that would replace certain supe...
Business Operations and StrategyPrivate Placements and Financing
Tempest Therapeutics Secures Flexible $50 Million Equity Facility
Positive
Aug 13, 2026
On August 13, 2026, Tempest Therapeutics entered into a purchase and registration rights agreement with Lincoln Park Capital Fund, under which Lincoln Park committed to buy up to $50 million of Tempest’s common stock over 24 months, starting...
Business Operations and StrategyShareholder Meetings
Tempest Therapeutics Adjourns Vote on Governance Changes
Neutral
Jul 28, 2026
On July 27, 2026, Tempest Therapeutics convened a special meeting of stockholders to seek approval of an amendment to its Restated Certificate of Incorporation that would eliminate certain supermajority voting requirements and allow stockholder ac...
Business Operations and StrategyProduct-Related Announcements
Tempest Therapeutics inks China in vivo CAR-T deal
Positive
Jul 22, 2026
On July 17, 2026, Tempest Therapeutics entered a collaboration agreement with Hebei Senlang Biotechnology to co-develop Tempest’s in vivo CAR-T product candidates in China, starting with TPST-4003. The deal positions Tempest to leverage Senl...
Private Placements and FinancingShareholder Meetings
Tempest Stockholders Approve Warrant-Related Share Issuances
Positive
Jun 23, 2026
On June 18, 2026, Tempest Therapeutics held a special meeting of stockholders at which investors approved the issuance of up to 925,927 shares of common stock upon exercise of outstanding Series A warrants and an additional 925,927 shares upon exe...
Executive/Board ChangesDelistings and Listing ChangesRegulatory Filings and Compliance
Tempest Therapeutics Announces CFO Transition and Board Changes
Neutral
Jun 4, 2026
On May 29, 2026, Tempest Therapeutics disclosed that Chief Financial Officer Nicholas Maestas had resigned effective June 5, 2026, and on that date the board appointed longtime finance executive Justin Trojanowski as Vice President, Finance, Princ...
Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Tempest Therapeutics Executes Warrant-Inducement Equity Financing Deal
Neutral
Jun 2, 2026
On May 28, 2026, Tempest Therapeutics entered into an inducement agreement with a holder of warrants originally issued in November 2025, cutting the exercise price from $3.50 to $1.73 per share in exchange for the holder exercising warrants for 1,...
Executive/Board Changes
Tempest Therapeutics Announces Resignation of Board Director
Neutral
May 29, 2026
On May 23, 2026, Tempest Therapeutics, Inc. announced that Ms. Simantov resigned from its Board of Directors, with the company stating it had not been informed of any disagreement related to its operations, policies, or practices underlying her de...
Executive/Board ChangesDelistings and Listing ChangesFinancial DisclosuresRegulatory Filings and Compliance
Tempest Therapeutics Faces Nasdaq Listing and Governance Risks
Negative
May 22, 2026
On May 19, 2026, Tempest Therapeutics received a deficiency notice from Nasdaq after reporting stockholders’ equity of $822,000 as of March 31, 2026, far below the $2.5 million minimum required for continued listing on the Nasdaq Capital Mar...
Executive/Board Changes
Tempest Therapeutics Announces Multiple Board Director Resignations
Neutral
May 22, 2026
On May 22, 2026, Tempest Therapeutics, Inc. announced that directors Stephen Brady, Michael Raab and Christine Pellizzari resigned from its board of directors, with the company stating it had not been informed of any disagreements related to opera...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2026