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Passage Bio (PASG)
NASDAQ:PASG
US Market
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Passage Bio (PASG) AI Stock Analysis

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PASG

Passage Bio

(NASDAQ:PASG)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
$5.50
▼(-52.87% Downside)
Action:ReiteratedDate:04/29/26
The score is held down primarily by weak financial quality (no revenue, ongoing cash burn, and sharply reduced equity with debt exceeding equity) and bearish technicals (price well below key moving averages with negative MACD). Valuation is difficult to assess due to negative earnings and no dividend support, while corporate events are mixed but skew negative given the scale of the restructuring.
Positive Factors
Clinical efficacy signals
Interim PBFT02 data show imaging and biomarker improvements plus durable CSF progranulin rises with generally tolerable safety. Those durable biological and imaging signals support a plausible disease‑modifying profile, strengthening the long‑term viability of the FTD program and partner interest.
Negative Factors
Deteriorating balance sheet
Equity fell sharply to a small capital base while debt stayed elevated, leaving debt greater than equity. This structural leverage deterioration reduces financial flexibility, raises refinancing and covenant risk, and heightens the likelihood of dilutive financings or forced strategic transactions under stress.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical efficacy signals
Interim PBFT02 data show imaging and biomarker improvements plus durable CSF progranulin rises with generally tolerable safety. Those durable biological and imaging signals support a plausible disease‑modifying profile, strengthening the long‑term viability of the FTD program and partner interest.
Read all positive factors

Passage Bio (PASG) vs. SPDR S&P 500 ETF (SPY)

Passage Bio Business Overview & Revenue Model

Company Description
Passage Bio, Inc., a genetic medicines company, develops transformative therapies for central nervous system diseases. It develops PBGM01, which utilizes a proprietary, AAVhu68 capsid to deliver to the brain and peripheral tissues a functional GLB...
How the Company Makes Money
Passage Bio has historically generated limited revenue because it does not have approved products on the market. Its funding and any recognized revenue have primarily come from (1) equity financings (e.g., public and/or private offerings) used to ...

Passage Bio Financial Statement Overview

Summary
Pre-revenue development-stage biotech with continued sizable losses (net loss improved to -$45.5M in 2025 from -$64.8M in 2024) and still-negative free cash flow (-$31.5M in 2025). The key drag is balance-sheet deterioration: equity fell to $18.8M in 2025 while debt remained about $24.0M, raising financial risk despite improving burn.
Income Statement
22
Negative
Balance Sheet
30
Negative
Cash Flow
26
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-728.00K0.00-3.72M0.000.00
EBITDA-42.42M-62.09M-98.34M-131.72M-176.19M
Net Income-45.52M-64.77M-102.06M-136.13M-185.39M
Balance Sheet
Total Assets62.28M102.41M150.54M243.55M355.08M
Cash, Cash Equivalents and Short-Term Investments46.30M76.76M114.29M189.61M315.77M
Total Debt24.01M25.48M26.29M27.11M0.00
Total Liabilities43.53M41.15M39.26M42.18M36.42M
Stockholders Equity18.75M61.26M111.28M201.37M318.66M
Cash Flow
Free Cash Flow-31.51M-47.99M-78.41M-123.48M-152.52M
Operating Cash Flow-31.51M-47.96M-78.26M-118.21M-126.88M
Investing Cash Flow40.22M54.95M65.24M25.20M-45.81M
Financing Cash Flow23.00K8.87M135.00K-1.35M166.66M

Passage Bio Technical Analysis

Technical Analysis Sentiment
Positive
Last Price11.67
Price Trends
50DMA
8.64
Positive
100DMA
10.12
Positive
200DMA
8.71
Positive
Market Momentum
MACD
0.89
Negative
RSI
65.83
Neutral
STOCH
94.12
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PASG, the sentiment is Positive. The current price of 11.67 is above the 20-day moving average (MA) of 8.79, above the 50-day MA of 8.64, and above the 200-day MA of 8.71, indicating a bullish trend. The MACD of 0.89 indicates Negative momentum. The RSI at 65.83 is Neutral, neither overbought nor oversold. The STOCH value of 94.12 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PASG.

Passage Bio Risk Analysis

Passage Bio disclosed 79 risk factors in its most recent earnings report. Passage Bio reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Passage Bio Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$114.37M-8.98-104.27%60.12%
46
Neutral
$24.67M-0.74-309.60%65.02%
44
Neutral
$65.27M-2.46-159.43%27.86%
43
Neutral
$11.08M-1.16-89.92%58.63%
42
Neutral
$18.32M-0.82-135.04%32.80%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PASG
Passage Bio
5.78
-0.74
-11.35%
TPST
Tempest Therapeutics
1.69
-5.42
-76.23%
CMMB
Chemomab Therapeutics
1.48
-3.93
-72.69%
ANVS
Annovis Bio
1.85
0.36
24.16%
CGTX
Cognition Therapeutics
1.28
0.85
197.67%

Passage Bio Corporate Events

Business Operations and Strategy
Passage Bio Announces Major Workforce Reduction and Restructuring
Negative
Apr 28, 2026
On April 28, 2026, Passage Bio, Inc., as part of its ongoing review of strategic alternatives to maximize shareholder value, announced a sweeping restructuring plan that will reduce its workforce by approximately 75% to lower operating expenses. T...
Business Operations and StrategyProduct-Related Announcements
Passage Bio Announces PBFT02 Data and Strategic Review
Neutral
Apr 20, 2026
On April 20, 2026, Passage Bio reported updated interim Phase 1/2 data from its upliFT-D trial showing that PBFT02 reduced whole brain and frontotemporal cortex atrophy and stabilized plasma neurofilament levels in frontotemporal dementia patients...
Business Operations and StrategyFinancial Disclosures
Passage Bio Ends Hopewell Lab Lease, Extends Cash Runway
Neutral
Mar 10, 2026
On March 4, 2026, Passage Bio, Inc. entered into a lease termination agreement with Hopewell Campus Owner LLC, ending a 15-year laboratory lease originally commenced in March 2021 for approximately 62,000 square feet of space. The company agreed t...
Business Operations and StrategyFinancial Disclosures
Passage Bio Reports 2025 Results, Advances FTD Program
Positive
Mar 3, 2026
On March 3, 2026, Passage Bio reported its fourth quarter and full-year 2025 results and detailed progress in its PBFT02 program for frontotemporal dementia. During 2025, the company enrolled the first three FTD-GRN patients into Cohort 3 of its g...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 29, 2026