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Cognition Therapeutics (CGTX)
NASDAQ:CGTX
US Market
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Cognition Therapeutics (CGTX) AI Stock Analysis

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CGTX

Cognition Therapeutics

(NASDAQ:CGTX)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$1.00
▼(-15.97% Downside)
Action:Reiterated
Date:05/09/26
The score is held back mainly by ongoing losses and cash burn with no reported revenue, despite a low-debt balance sheet. Technicals are mildly positive in the near/intermediate term, and recent corporate updates (progress toward a registrational pathway plus runway through Q2 2027) provide supportive upside context, while valuation inputs are not informative due to lack of meaningful P/E and no dividend yield.
Positive Factors
Regulatory/Clinical Progress
Cognition has moved zervimesine toward a formal registrational development path for DLB psychosis after strong Phase 2 SHIMMER results and FDA interactions. This is a durable fundamental because regulatory alignment can materially de‑risk development and enable a clear path to approval and market access if pivotal trials succeed.
Negative Factors
Persistent Pre‑Revenue Losses
The firm remains pre‑revenue with material operating losses and negative cash generation. Sustained negative EBIT and cash flow make long‑term value creation contingent on clinical success and eventual commercialization, raising execution risk and the potential for further capital raises if milestones slip.
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Positive Factors
Negative Factors
Regulatory/Clinical Progress
Cognition has moved zervimesine toward a formal registrational development path for DLB psychosis after strong Phase 2 SHIMMER results and FDA interactions. This is a durable fundamental because regulatory alignment can materially de‑risk development and enable a clear path to approval and market access if pivotal trials succeed.
Read all positive factors

Cognition Therapeutics (CGTX) vs. SPDR S&P 500 ETF (SPY)

Cognition Therapeutics Business Overview & Revenue Model

Company Description
Cognition Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of small molecule therapeutics targeting age-related degenerative diseases and disorders of the central nervous system and retina. I...
How the Company Makes Money
As a clinical-stage biotechnology company, Cognition Therapeutics does not primarily generate recurring revenue from marketed products. The company funds operations mainly through external financing (e.g., proceeds from equity offerings such as it...

Cognition Therapeutics Earnings Call Summary

Earnings Call Date:Mar 20, 2025
(Q4-2024)
|
% Change Since: |
Next Earnings Date:Aug 11, 2026
Earnings Call Sentiment Neutral
The earnings call highlights significant progress in clinical efficacy signals and strategic cost management, extending the cash runway. However, challenges remain with increased net losses, NASDAQ compliance issues, and uncertain funding partnerships. The sentiment is balanced by advancements in manufacturing and patent filings.
Positive Updates
Strong Efficacy Signals for Zervimesine
The company reported strong efficacy signals from two studies involving Alzheimer's disease and dementia with Lewy bodies (DLB), indicating potential value for patients and investors.
Negative Updates
Net Loss Increase
The company reported a net loss of $34 million for the year ended December 31, 2024, compared to a net loss of $25.8 million in 2023, despite a decrease in general and administrative expenses.
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Q4-2024 Updates
Negative
Strong Efficacy Signals for Zervimesine
The company reported strong efficacy signals from two studies involving Alzheimer's disease and dementia with Lewy bodies (DLB), indicating potential value for patients and investors.
Read all positive updates
Company Guidance
During the Cognition Therapeutics Fourth Quarter and Full Year 2024 Earnings Call, the company provided guidance on advancing their lead candidate, zervimesine (CT1812), into registrational trials for Alzheimer's disease and dementia with Lewy bodies (DLB). The company plans to submit final study documents to the FDA and request end of Phase II meetings for both indications. Their strategic decision to conclude the Phase II dry AMD study was made to focus resources on Alzheimer's and DLB programs, extending their cash runway into Q4 2025. Cognition reported a net loss of $34 million for 2024 and utilized an ATM facility to raise $12.8 million. They hold approximately $25 million in cash and $50 million in obligated grant funds. The company is also working on securing non-dilutive funding and is confident in regaining NASDAQ compliance within the allotted grace period.

Cognition Therapeutics Financial Statement Overview

Summary
Overall financials reflect a development-stage, pre-revenue biotech: revenue is $0 with persistent operating losses (TTM EBIT about -$42.8M) and ongoing cash burn (TTM operating/free cash flow about -$20.3M). The balance sheet is a relative strength with very low leverage (TTM debt-to-equity ~0.01) and positive equity (~$29.9M), and net loss and burn have improved versus prior years, but self-funding capacity remains weak.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
25
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-129.00K0.000.00-252.00K-235.00K0.00
EBITDA-23.57M-23.25M-33.68M-25.51M-21.13M-10.73M
Net Income-19.58M-23.49M-33.97M-25.79M757.00K-11.72M
Balance Sheet
Total Assets36.14M48.39M30.23M35.16M50.42M59.14M
Cash, Cash Equivalents and Short-Term Investments31.13M36.81M25.01M29.92M41.56M54.72M
Total Debt465.00K638.00K814.00K1.24M1.48M0.00
Total Liabilities6.23M14.12M11.48M10.69M10.18M7.86M
Stockholders Equity29.91M34.27M18.75M24.47M40.25M51.27M
Cash Flow
Free Cash Flow-20.25M-24.59M-28.48M-16.16M-18.70M-3.66M
Operating Cash Flow-20.25M-24.59M-28.47M-16.02M-18.53M-3.63M
Investing Cash Flow9.00K9.00K-4.00K-147.00K-171.00K-27.00K
Financing Cash Flow35.04M36.57M23.57M4.52M5.55M53.20M

Cognition Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.19
Price Trends
50DMA
1.03
Positive
100DMA
1.25
Negative
200DMA
1.37
Negative
Market Momentum
MACD
<0.01
Negative
RSI
62.42
Neutral
STOCH
96.15
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CGTX, the sentiment is Positive. The current price of 1.19 is above the 20-day moving average (MA) of 0.95, above the 50-day MA of 1.03, and below the 200-day MA of 1.37, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 62.42 is Neutral, neither overbought nor oversold. The STOCH value of 96.15 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CGTX.

Cognition Therapeutics Risk Analysis

Cognition Therapeutics disclosed 85 risk factors in its most recent earnings report. Cognition Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cognition Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$102.03M-3.71-72.68%64.57%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$187.37M-1.49-656.82%17.64%
48
Neutral
$250.91M-1.17-60.15%74.84%99.51%
48
Neutral
$806.46M-7.05-48.16%-6.01%
47
Neutral
$71.79M-0.90-80.35%27.27%
46
Neutral
$202.89M-4.12-977.67%43.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CGTX
Cognition Therapeutics
1.14
0.81
245.45%
TNXP
Tonix Pharma
15.74
-10.86
-40.83%
ACET
Adicet Bio
7.68
-3.61
-31.98%
MIST
Milestone Pharmaceuticals
1.51
0.21
16.67%
ELTX
Elicio Therapeutics
10.63
4.79
82.02%
ANRO
Alto Neuroscience, Inc.
22.98
20.44
804.72%

Cognition Therapeutics Corporate Events

Business Operations and StrategyFinancial Disclosures
Cognition Therapeutics Highlights 2025 Results, Zervimesine Progress
Positive
Mar 26, 2026
On March 26, 2026, Cognition Therapeutics reported fourth-quarter and full-year 2025 results and detailed progress in advancing its lead drug zervimesine for neurodegenerative indications. The company is prioritizing development of zervimesine for...
Business Operations and StrategyProduct-Related Announcements
Cognition Therapeutics Advances Zervimesine for DLB Psychosis
Positive
Mar 2, 2026
On March 2, 2026, Cognition Therapeutics announced plans to advance zervimesine (CT1812) into a registrational development path for dementia with Lewy bodies (DLB) psychosis, following receipt of final minutes from a January 21, 2026, FDA Type C m...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 09, 2026