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Generation Bio Co. (GBIO)
:GBIO
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Generation Bio (GBIO) AI Stock Analysis

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GBIO

Generation Bio

(NASDAQ:GBIO)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
$5.50
▼(-4.51% Downside)
Generation Bio's overall stock score is primarily impacted by its weak financial performance and poor valuation metrics. While technical analysis shows some stability, the company's significant financial challenges and lack of profitability weigh heavily on the stock's attractiveness.
Positive Factors
Innovative Technology
The ceDNA platform offers a competitive advantage in gene therapy, potentially leading to breakthrough treatments for genetic disorders, enhancing long-term growth prospects.
Revenue Growth Potential
Strong revenue growth potential from strategic partnerships and licensing agreements positions the company for future financial sustainability and expansion in the biotech sector.
High Gross Profit Margin
A high gross profit margin indicates efficient production and potential for profitability improvement, supporting long-term financial health if operational inefficiencies are addressed.
Negative Factors
High Leverage
Significant leverage increases financial risk, potentially limiting the company's ability to invest in growth opportunities and affecting long-term stability.
Negative Cash Flow
Persistent negative cash flows indicate challenges in sustaining operations without external funding, affecting the company's ability to finance future growth and innovation.
Profitability Challenges
Severe profitability issues and declining revenue growth highlight operational inefficiencies, posing a significant threat to long-term financial viability and market competitiveness.

Generation Bio (GBIO) vs. SPDR S&P 500 ETF (SPY)

Generation Bio Business Overview & Revenue Model

Company DescriptionGeneration Bio Co., a genetic medicines company, develops therapies for the treatment of rare and prevalent diseases. The company provides a portfolio of programs, including programs for rare and prevalent diseases of the liver and retina. It also focuses on the diseases of skeletal muscle, central nervous system, and oncology. The company was formerly known as Torus Therapeutics, Inc. and changed its name to Generation Bio Co. in November 2017. Generation Bio Co. was incorporated in 2016 and is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyGeneration Bio makes money through the development and potential commercialization of its proprietary gene therapy platforms. The company's primary revenue streams are expected to come from partnerships with other biotechnology and pharmaceutical companies, as well as potential licensing agreements. These partnerships may involve collaborative research, co-development of therapies, and milestone payments associated with successful development stages. Additionally, Generation Bio may generate revenue from royalties on sales of successfully commercialized therapies developed through its platform. The company's strategic focus on innovation and collaboration in the gene therapy space is crucial for its financial sustainability and growth.

Generation Bio Financial Statement Overview

Summary
Generation Bio faces significant financial challenges, with persistent losses and high leverage. Despite a strong gross profit margin, the company struggles with profitability and cash flow management. High debt levels and negative returns on equity highlight potential risks.
Income Statement
35
Negative
Generation Bio's income statement shows significant challenges with profitability. The TTM data indicates a negative net profit margin of -341.12%, and a declining revenue growth rate of -13.55%. Despite a high gross profit margin of 96.40%, the company struggles with negative EBIT and EBITDA margins, reflecting operational inefficiencies and high costs relative to revenue.
Balance Sheet
45
Neutral
The balance sheet reveals a high debt-to-equity ratio of 1.58 in the TTM, indicating significant leverage. The return on equity is negative at -91.07%, suggesting that the company is not generating sufficient returns on shareholders' equity. The equity ratio is not explicitly calculated, but the high leverage poses a risk to financial stability.
Cash Flow
40
Negative
Cash flow analysis shows negative operating and free cash flows, with a slight improvement in free cash flow growth at -4.96% in the TTM. The operating cash flow to net income ratio is negative, indicating cash flow challenges. The free cash flow to net income ratio is slightly above 1, suggesting that free cash flow is marginally covering net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue21.23M19.89M5.90M0.000.000.00
Gross Profit21.23M19.89M-71.03M-5.13M-4.53M-3.43M
EBITDA-69.92M-74.26M-133.30M-136.05M-114.57M-77.68M
Net Income-72.42M-131.67M-126.61M-136.64M-119.15M-80.52M
Balance Sheet
Total Assets179.43M231.20M374.76M376.26M476.77M294.15M
Cash, Cash Equivalents and Short-Term Investments141.36M185.22M264.36M279.09M375.14M262.33M
Total Debt85.32M93.56M97.89M81.71M80.83M0.00
Total Liabilities125.33M144.99M171.63M93.77M95.03M26.14M
Stockholders Equity54.10M86.20M203.13M282.49M381.75M268.01M
Cash Flow
Free Cash Flow-81.69M-90.96M-60.14M-111.25M-97.78M-75.66M
Operating Cash Flow-80.52M-88.56M-52.74M-102.45M-91.82M-70.14M
Investing Cash Flow100.90M94.53M-9.70M-192.51M193.05M-205.20M
Financing Cash Flow214.00K250.00K35.82M12.99M214.67M323.10M

Generation Bio Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.76
Price Trends
50DMA
5.42
Positive
100DMA
4.60
Positive
200DMA
5.88
Negative
Market Momentum
MACD
0.07
Positive
RSI
50.15
Neutral
STOCH
41.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GBIO, the sentiment is Negative. The current price of 5.76 is below the 20-day moving average (MA) of 5.92, above the 50-day MA of 5.42, and below the 200-day MA of 5.88, indicating a neutral trend. The MACD of 0.07 indicates Positive momentum. The RSI at 50.15 is Neutral, neither overbought nor oversold. The STOCH value of 41.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for GBIO.

Generation Bio Risk Analysis

Generation Bio disclosed 84 risk factors in its most recent earnings report. Generation Bio reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Generation Bio Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
50
Neutral
347.25M-2.121542.93%-40.16%78.28%
46
Neutral
28.85M-4.8567.43%88.13%92.45%
45
Neutral
$38.80M-85.45%61.15%54.71%
44
Neutral
24.07M-0.4232.57%
41
Neutral
119.10M-2.0529.58%
30
Underperform
30.51M-2.1231.09%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GBIO
Generation Bio
5.76
-18.54
-76.30%
TVRD
Tvardi Therapeutics
37.03
26.05
237.25%
DARE
Daré Bioscience
2.08
-1.19
-36.39%
PASG
Passage Bio
7.68
-6.00
-43.86%
CGTX
Cognition Therapeutics
1.26
0.84
200.00%
NRSN
Neurosense Therapeutics Ltd.
1.18
-0.10
-7.81%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 23, 2025