Competitive ChallengesThe latest dataset underscores several emerging questions about TERN-701's differentiation, competitive durability, and strategic positioning within the CML landscape.
Product Efficacy ConcernsThe efficacy demonstrated at the 12-week mark is not sufficient to be competitive with other oral GLP-1 therapies currently in development.
Safety ConcernsThere were two patients with drug-related liver toxicity, which led to the decision not to advance TERN-601.