Market PotentialOlema currently estimates the 1L market in combination with a CDK4/6i at over ~$10B, representing one of the most coveted commercial settings in oncology.
Partnerships And CollaborationsOlema announced a clinical trial agreement with Pfizer to explore palazestrant combined with atirmociclib for the treatment of metastatic breast cancer.
Trial DevelopmentsNovartis is collaborating on the OPERA-02 trial by providing a free drug supply of ribociclib, valued at $275 million, which shows strong support and confidence in the study.