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Olema Pharmaceuticals (OLMA)
NASDAQ:OLMA
US Market
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Olema Pharmaceuticals (OLMA) AI Stock Analysis

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OLMA

Olema Pharmaceuticals

(NASDAQ:OLMA)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$14.00
▼(-16.77% Downside)
Action:ReiteratedDate:04/30/26
Overall score is pulled down primarily by persistent, widening losses and accelerating cash burn, plus a clearly bearish technical setup (price below key moving averages and negative MACD). The main offset is a strong, low-leverage balance sheet that provides financial flexibility, but valuation is not supportive due to negative earnings and no dividend.
Positive Factors
Low-Leverage Balance Sheet
A very low debt load versus sizable equity provides durable financial flexibility for a clinical-stage biotech. It reduces near-term insolvency and interest burdens, enabling Olema to fund trials, pursue partnerships or non-dilutive options and negotiate better deal terms as programs mature.
Negative Factors
Accelerating Cash Burn
Rapidly increasing negative operating cash flow is a persistent structural risk: it raises near-term funding needs, increases dilution or debt dependence, and could force financing decisions that affect strategy or timelines while late-stage trials demand sustained capital.
Read all positive and negative factors
Positive Factors
Negative Factors
Low-Leverage Balance Sheet
A very low debt load versus sizable equity provides durable financial flexibility for a clinical-stage biotech. It reduces near-term insolvency and interest burdens, enabling Olema to fund trials, pursue partnerships or non-dilutive options and negotiate better deal terms as programs mature.
Read all positive factors

Olema Pharmaceuticals (OLMA) vs. SPDR S&P 500 ETF (SPY)

Olema Pharmaceuticals Business Overview & Revenue Model

Company Description
Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. Its lead product candidate is OP-1250, an estrogen receptor (ER) antagonist and...
How the Company Makes Money
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Olema Pharmaceuticals Financial Statement Overview

Summary
Financial profile is mixed: a strong, low-debt balance sheet (very low debt vs. sizable equity) supports flexibility, but the company remains pre-revenue with materially widening losses and accelerating operating cash burn, elevating funding and dilution risk.
Income Statement
18
Very Negative
Balance Sheet
72
Positive
Cash Flow
24
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit0.000.000.000.000.00
EBITDA-178.21M-141.87M-104.58M-106.63M-71.33M
Net Income-162.45M-129.47M-96.66M-104.79M-71.10M
Balance Sheet
Total Assets533.43M450.98M276.94M215.65M295.94M
Cash, Cash Equivalents and Short-Term Investments505.44M434.09M261.81M204.42M287.25M
Total Debt1.19M1.43M2.42M2.56M3.29M
Total Liabilities54.87M42.02M23.05M18.10M11.38M
Stockholders Equity478.56M408.96M253.90M197.55M284.57M
Cash Flow
Free Cash Flow-146.72M-104.51M-83.73M-82.43M-52.27M
Operating Cash Flow-146.72M-104.35M-83.73M-82.06M-50.69M
Investing Cash Flow-155.76M-93.53M-4.85M91.48M-275.44M
Financing Cash Flow211.30M268.82M133.41M476.00K1.39M

Olema Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price16.82
Price Trends
50DMA
18.81
Negative
100DMA
23.13
Negative
200DMA
15.34
Positive
Market Momentum
MACD
-0.45
Negative
RSI
52.24
Neutral
STOCH
82.03
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OLMA, the sentiment is Neutral. The current price of 16.82 is above the 20-day moving average (MA) of 15.17, below the 50-day MA of 18.81, and above the 200-day MA of 15.34, indicating a neutral trend. The MACD of -0.45 indicates Negative momentum. The RSI at 52.24 is Neutral, neither overbought nor oversold. The STOCH value of 82.03 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for OLMA.

Olema Pharmaceuticals Risk Analysis

Olema Pharmaceuticals disclosed 89 risk factors in its most recent earnings report. Olema Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Olema Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$227.36M8.7114.25%6774.96%
52
Neutral
$870.96M-5.604438.87%144.57%32.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$672.23M-9.53-14.25%-0.30%56.14%
47
Neutral
$1.25B-13.39-42.90%13.36%
46
Neutral
$352.97M-12.74-43.61%-100.00%-20.71%
41
Neutral
$86.79M-3.72264.70%-57.74%-199.96%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OLMA
Olema Pharmaceuticals
14.63
9.07
163.13%
MGTX
Meiragtx Holdings
9.70
3.25
50.39%
ARVN
Arvinas Holding Company
10.78
3.15
41.28%
GOSS
Gossamer Bio
0.35
-0.90
-72.00%
KROS
Keros Therapeutics
11.71
-2.85
-19.57%
CMPX
Compass Therapeutics
1.94
0.08
4.30%

Olema Pharmaceuticals Corporate Events

Business Operations and StrategyExecutive/Board Changes
Olema Pharmaceuticals Adds Veteran Director to Support Growth
Positive
Apr 29, 2026
Olema Oncology, the operating name of Olema Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company focused on targeted therapies for breast cancer and other endocrine-driven cancers, with its lead drug palazestrant in two Phase 3 tri...
Executive/Board Changes
Olema Pharmaceuticals CFO Departs; CEO Assumes Interim Role
Neutral
Jan 30, 2026
On January 30, 2026, Olema Pharmaceuticals, Inc. announced that Chief Operating and Financial Officer Shane Kovacs departed the company on that date to pursue new opportunities, though he will remain as a consultant through August 1, 2026 under a ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 30, 2026