Olema Pharmaceuticals, Inc. (OLMA)
NASDAQ:OLMA
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Olema Pharmaceuticals
(NASDAQ:OLMA)
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Rating:48Neutral
Price Target:
$14.00
▼(-16.77% Downside)
Action:Reiterated
Date:05/22/26
Score is held back primarily by pre-revenue financials with widening losses and substantial ongoing cash burn, alongside weak technical momentum (below key moving averages and negative MACD). Offsetting factors include a strong, low-debt balance sheet and positive recent corporate updates, particularly encouraging early clinical data and continued late-stage program progress.
Positive Factors
Low-leverage balance sheet
Extremely low debt and a materially larger equity base reduce refinancing risk and preserve strategic optionality. This durable balance-sheet strength supports continued R&D investment, potential licensing or partnering, and a longer runway versus highly leveraged peers while clinical programs mature.
Negative Factors
Pre-revenue operating model
No product revenue means the company cannot self-fund operations and remains fully dependent on external financing or milestone/partner revenues. That structural absence of cash generation makes the business highly binary on trial outcomes and raises sustained financing and execution risk.
Read all positive and negative factors
Positive Factors
Negative Factors
Low-leverage balance sheet
Extremely low debt and a materially larger equity base reduce refinancing risk and preserve strategic optionality. This durable balance-sheet strength supports continued R&D investment, potential licensing or partnering, and a longer runway versus highly leveraged peers while clinical programs mature.
Read all positive factors
Olema Pharmaceuticals (OLMA) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$1.19B
Dividend YieldN/A
Average Volume (3M)978.63K
Price to Earnings (P/E)―
Beta (1Y)1.04
Revenue GrowthN/A
EPS Growth-3.83%
CountryUS
Employees96
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-2.02
Shares Outstanding87,347,470
10 Day Avg. Volume1,269,525
30 Day Avg. Volume978,632
Financial Highlights & Ratios
PEG Ratio0.89
Price to Book (P/B)4.55
Price to Sales (P/S)0.00
P/FCF Ratio-14.83
Enterprise Value/Market Cap0.96
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-3.74K
Enterprise Value/Ebitda-5.78
Forecast
1Y Price Target
$41.11Price Target Upside144.42% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering11
EPS Forecast (FY)-2.2
Revenue Forecast (FY)$2.05M
Olema Pharmaceuticals Business Overview & Revenue Model
Company Description
Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. Its lead product candidate is OP-1250, an estrogen receptor (ER) antagonist and...
How the Company Makes Money
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Olema Pharmaceuticals Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
72
Positive
Cash Flow
22
Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Gross Profit | -306.00K | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| EBITDA | -197.67M | -178.21M | -141.87M | -104.58M | -106.63M | -71.33M |
| Net Income | -185.15M | -162.45M | -129.47M | -96.66M | -104.79M | -71.10M |
Balance Sheet | ||||||
| Total Assets | 530.64M | 533.43M | 450.98M | 276.94M | 215.65M | 295.94M |
| Cash, Cash Equivalents and Short-Term Investments | 505.35M | 505.44M | 434.09M | 261.81M | 204.42M | 287.25M |
| Total Debt | 956.00K | 1.19M | 1.43M | 2.42M | 2.56M | 3.29M |
| Total Liabilities | 50.17M | 54.87M | 42.02M | 23.05M | 18.10M | 11.38M |
| Stockholders Equity | 480.48M | 478.56M | 408.96M | 253.90M | 197.55M | 284.57M |
Cash Flow | ||||||
| Free Cash Flow | -148.72M | -146.72M | -104.51M | -83.73M | -82.43M | -52.27M |
| Operating Cash Flow | -148.72M | -146.72M | -104.35M | -83.73M | -82.06M | -50.69M |
| Investing Cash Flow | -106.15M | -155.76M | -93.53M | -4.85M | 91.48M | -275.44M |
| Financing Cash Flow | 256.78M | 211.30M | 268.82M | 133.41M | 476.00K | 1.39M |
Olema Pharmaceuticals Technical Analysis
Negative
16.82
Price Trends
14.89
Negative
19.64
Negative
16.56
Negative
Market Momentum
-0.59
Negative
40.79
Neutral
47.40
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OLMA, the sentiment is Negative. The current price of 16.82 is above the 20-day moving average (MA) of 14.24, above the 50-day MA of 14.89, and above the 200-day MA of 16.56, indicating a bearish trend. The MACD of -0.59 indicates Negative momentum. The RSI at 40.79 is Neutral, neither overbought nor oversold. The STOCH value of 47.40 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OLMA.
Olema Pharmaceuticals Risk Analysis
Olema Pharmaceuticals disclosed 91 risk factors in its most recent earnings report. Olema Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Olema Pharmaceuticals Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
56 Neutral | $855.71M | -3.80 | 474.91% | ― | 131.13% | 35.61% | |
54 Neutral | $221.47M | -4.33 | -17.04% | ― | -84.55% | -1998.74% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
49 Neutral | $586.50M | -2.94 | -44.39% | ― | -79.06% | -397.92% | |
48 Neutral | $1.19B | -7.22 | -45.95% | ― | ― | -3.83% | |
43 Neutral | $49.31M | -0.41 | 174.85% | ― | -55.42% | -248.85% | |
42 Neutral | $372.78M | -13.46 | -39.75% | ― | -100.00% | -2.72% |
* Healthcare Sector Average
OLMA
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Olema Pharmaceuticals Corporate Events
Business Operations and StrategyProduct-Related Announcements
Olema Highlights Encouraging OP-3136 Phase 1 Oncology Results
Positive
May 21, 2026
On May 21, 2026, Olema Oncology reported preliminary Phase 1 data for OP-3136, an oral KAT6 inhibitor, in heavily pretreated patients with ER+/HER2- advanced breast cancer, metastatic castration-resistant prostate cancer, and metastatic non-small ...
Business Operations and Strategy
Olema Pharmaceuticals Signs New Headquarters Lease at Oyster Point
Neutral
May 1, 2026
On April 27, 2026, Olema Pharmaceuticals entered into a seven-year lease with KR Oyster Point II, LLC for about 38,176 square feet of office space across the fourth and fifth floors of a building at Oyster Point, with plans to relocate its corpora...
Business Operations and StrategyExecutive/Board Changes
Olema Pharmaceuticals Adds Veteran Director to Support Growth
Positive
Apr 29, 2026
Olema Oncology, the operating name of Olema Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company focused on targeted therapies for breast cancer and other endocrine-driven cancers, with its lead drug palazestrant in two Phase 3 tri...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.