ARS Pharmaceuticals (SPRY)
NASDAQ:SPRY
US Market
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ARS Pharmaceuticals (SPRY) AI Stock Analysis

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SPRY

ARS Pharmaceuticals

(NASDAQ:SPRY)

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Neutral 52 (OpenAI - 4o)
Rating:52Neutral
Price Target:
$8.50
▲(20.06% Upside)
The overall stock score reflects strong revenue growth and strategic initiatives, but is tempered by ongoing profitability challenges and bearish technical indicators. The earnings call provided positive guidance, but valuation concerns and technical analysis suggest caution.
Positive Factors
Revenue Growth
Significant revenue growth indicates strong market acceptance and demand for Nephi, suggesting robust future earnings potential.
Global Expansion
Global expansion into new markets enhances revenue diversification and positions ARS for long-term growth in international markets.
Patent Protection
Strong patent protection secures ARS's competitive edge, safeguarding its innovations and supporting sustained market leadership.
Negative Factors
Profitability Challenges
Ongoing profitability issues could hinder reinvestment and growth, posing a risk to long-term financial health and shareholder value.
High Investing Cash Flows
High capital expenditures may strain cash reserves, limiting flexibility for future strategic investments or operational needs.
Market Share Growth Challenge
Challenges in maintaining market share growth could impact competitive positioning and slow revenue momentum in key periods.

ARS Pharmaceuticals (SPRY) vs. SPDR S&P 500 ETF (SPY)

ARS Pharmaceuticals Business Overview & Revenue Model

Company DescriptionARS Pharmaceuticals, Inc. (SPRY) is a biopharmaceutical company focused on developing innovative therapies for respiratory diseases. The company is known for its core product, neffy, a needle-free delivery system for epinephrine, aimed at treating severe allergic reactions and anaphylaxis. ARS Pharmaceuticals operates primarily in the healthcare sector, leveraging advanced delivery technologies to enhance patient experiences and improve outcomes in emergency situations.
How the Company Makes MoneyARS Pharmaceuticals generates revenue primarily through the commercialization of its products, particularly neffy. The company monetizes its innovations through direct sales to healthcare providers and pharmacies, as well as potential partnerships with larger pharmaceutical companies for distribution and marketing. In addition to product sales, ARS may also benefit from licensing agreements, research collaborations, and government contracts related to public health initiatives. As neffy gains market acceptance, its sales are expected to be a significant contributor to the company's earnings, bolstered by ongoing investments in marketing and education to raise awareness among healthcare professionals and patients.

ARS Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 10, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Neutral
The call highlighted significant revenue growth and strategic initiatives like the 'Get Nephi On Us' program and global expansion. However, challenges such as temporary pauses in market share growth, data inaccuracies, and expected Q4 sales decline were noted.
Q3-2025 Updates
Positive Updates
Significant Revenue Growth
U.S. net product revenue for Nephi reached $31.3 million in Q3, representing a 2.5-fold increase from the prior quarter and exceeding consensus expectations of $28.3 million.
Global Expansion and Approvals
Nephi received approval in Japan with launch anticipated in 2025, expected approvals in Canada and China by 2026.
Positive Market Feedback and Real-World Data
Real-world data shows Nephi effectively treats anaphylaxis with a single dose in nine out of ten patients, aligning with epinephrine injections.
Launch of 'Get Nephi On Us' Program
Introduced a program to simplify access to Nephi with virtual prescriber interactions at no cost, anticipated to accelerate sales.
Strong Cash Position
Ended Q3 with $288 million in cash, cash equivalents, and short-term investments, supported by a $250 million term loan facility.
Negative Updates
Market Share Growth Challenge
Experienced a temporary pause in market share growth during the back-to-school season due to high patient volume and limited appointment time.
IQVIA Data Inaccuracy
IQVIA script data not accurately reflecting Nephi's revenue trajectory, with significant sales not captured in their data sets.
Anticipated Q4 Sales Decline
Q4 sales expected to decrease from Q3 due to typical seasonality and holiday decline in the epinephrine market.
Company Guidance
The guidance provided in the call highlighted several key metrics and strategic initiatives for ARS Pharmaceuticals. U.S. net product revenue for Nephi reached $31.3 million in Q3 2025, marking a 2.5-fold increase from the previous quarter and surpassing consensus expectations of $28.3 million. The company noted strong growth in new patient starts and overall demand, with Nephi's market share among new prescribers reaching 10.3%. The Get Nephi On Us program was introduced to facilitate easier access and prescriptions, aiming to drive sales growth despite typical seasonal declines in Q4. The company also reported a significant increase in consumer awareness, up from 20% pre-campaign to 56% by September. Additionally, the company ended Q3 with $288.2 million in cash and investments, bolstered by a $250 million term loan facility. The call emphasized ongoing investments in commercialization and international expansion, with expectations for approvals in Japan, Canada, and China by 2026.

ARS Pharmaceuticals Financial Statement Overview

Summary
ARS Pharmaceuticals has shown strong revenue growth and improved net income, indicating operational improvements. The balance sheet is robust with low leverage and improving equity, but cash flow statements show caution due to high investing activities. Profitability remains a challenge, though recent trends show potential for future stabilization and growth.
Income Statement
45
Neutral
ARS Pharmaceuticals showed significant revenue growth from 2023 to 2024, with total revenue jumping from $30,000 to $89,149,000, indicating strong potential. However, the company has struggled with profitability, evidenced by negative EBIT and EBITDA margins over the years. The net profit margin turned positive in 2024, a promising sign, but overall profitability remains inconsistent.
Balance Sheet
62
Positive
The balance sheet reveals a strong equity position, with stockholders' equity growing from negative figures in earlier years to a robust $256,798,000 in 2024. The debt-to-equity ratio is low, indicating low leverage risk. The equity ratio has improved, suggesting increased financial stability. However, fluctuations in total liabilities reflect some instability.
Cash Flow
55
Neutral
Cash flow analysis shows a turnaround, with free cash flow becoming positive in 2024 after previous negative years. Operating cash flow to net income ratio improved, signaling better cash generation relative to income. However, investing cash flows were significantly negative, highlighting high capital expenditures or investments.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue142.77M89.15M30.00K1.32M5.51M17.84M
Gross Profit121.66M68.59M30.00K1.32M5.29M3.77M
EBITDA-83.07M-3.00M-67.45M-35.20M-19.24M-463.00K
Net Income-80.04M8.00M-54.37M-34.68M-20.24M-1.06M
Balance Sheet
Total Assets372.80M351.15M233.19M281.44M61.45M26.41M
Cash, Cash Equivalents and Short-Term Investments288.21M314.02M228.36M274.38M60.06M24.52M
Total Debt1.53M42.00K274.00K481.00K9.03M10.02M
Total Liabilities225.15M94.36M2.43M8.55M92.72M40.46M
Stockholders Equity147.66M256.80M230.76M272.89M-31.27M-14.05M
Cash Flow
Free Cash Flow-86.02M12.98M-59.44M-40.28M-17.62M8.15M
Operating Cash Flow-85.38M13.55M-59.27M-40.08M-17.56M9.07M
Investing Cash Flow-69.11M-106.10M-87.18M-199.00K-55.00K-917.00K
Financing Cash Flow174.38M72.40M6.90M190.73M53.16M5.10M

ARS Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price7.08
Price Trends
50DMA
9.62
Negative
100DMA
12.69
Negative
200DMA
13.02
Negative
Market Momentum
MACD
-0.64
Positive
RSI
28.53
Positive
STOCH
3.99
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SPRY, the sentiment is Negative. The current price of 7.08 is below the 20-day moving average (MA) of 8.75, below the 50-day MA of 9.62, and below the 200-day MA of 13.02, indicating a bearish trend. The MACD of -0.64 indicates Positive momentum. The RSI at 28.53 is Positive, neither overbought nor oversold. The STOCH value of 3.99 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SPRY.

ARS Pharmaceuticals Risk Analysis

ARS Pharmaceuticals disclosed 72 risk factors in its most recent earnings report. ARS Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ARS Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$1.16B1,223.610.44%26.54%
59
Neutral
$1.57B-36.13%
55
Neutral
$1.32B-25.81-36.87%15.84%
52
Neutral
$723.57M-45.92%5459.66%-59.70%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
$1.19B-39.73%4.29%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SPRY
ARS Pharmaceuticals
7.08
-6.47
-47.75%
TRVI
Trevi Therapeutics
11.31
8.54
308.30%
ORIC
Oric Pharmaceuticals
11.90
3.16
36.16%
PHAR
Pharming Group
15.91
8.23
107.16%
MAZE
Maze Therapeutics, Inc.
33.23
18.23
121.53%
SION
Sionna Therapeutics, Inc.
39.12
16.88
75.90%

ARS Pharmaceuticals Corporate Events

ARS Pharmaceuticals Reports Strong Q3 2025 Growth
Nov 11, 2025

ARS Pharmaceuticals, Inc., a biopharmaceutical company, focuses on empowering patients and caregivers to manage allergic reactions, particularly through its innovative needle-free epinephrine nasal spray, neffy.

Ars Pharmaceuticals’ Earnings Call Highlights Growth and Challenges
Nov 11, 2025

During Ars Pharmaceuticals, Inc.’s latest earnings call, the sentiment was largely positive, underscored by significant revenue growth and strategic initiatives. The company celebrated the success of its ‘Get Nephi On Us’ program and global expansion plans. However, challenges such as temporary pauses in market share growth, data inaccuracies, and an anticipated decline in Q4 sales were acknowledged.

Business Operations and StrategyFinancial Disclosures
ARS Pharmaceuticals Reports Q3 2025 Financial Results
Neutral
Nov 10, 2025

On November 10, 2025, ARS Pharmaceuticals reported its third-quarter financial results, highlighting $32.5 million in revenue, primarily from U.S. sales of neffy®. The company is actively expanding its market presence with direct-to-consumer campaigns and strategic initiatives to increase prescriber confidence and patient access. Despite a net loss of $51.2 million, ARS Pharmaceuticals maintains a strong cash position to support its operations and growth. The company is also progressing with the global expansion of neffy, having received approval in Japan and launched EURneffy® in the U.K., with further regulatory approvals anticipated in Canada and China. These efforts are expected to enhance ARS Pharmaceuticals’ industry positioning and stakeholder engagement.

The most recent analyst rating on (SPRY) stock is a Buy with a $30.00 price target. To see the full list of analyst forecasts on ARS Pharmaceuticals stock, see the SPRY Stock Forecast page.

Ars Pharmaceuticals’ Latest Study: A Potential Game-Changer in Allergy Treatment
Oct 27, 2025

Study Overview: Ars Pharmaceuticals, Inc. is conducting a Phase IV study titled ‘A Phase IV Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy.’ The study aims to assess the safety and efficacy of Neffy, an epinephrine nasal spray, and intramuscular Adrenalin in managing allergic reactions following oral food challenges or allergen immunotherapy. This research holds significant importance in potentially offering a more convenient treatment option for allergic reactions.

Ars Pharmaceuticals’ Promising Study on ARS-2 for Chronic Urticaria: What Investors Need to Know
Oct 27, 2025

Study Overview: Ars Pharmaceuticals, Inc. is conducting a study titled ‘An Outpatient, Randomized, Double-Blinded, Placebo-Controlled, Cross-Over Study of the Efficacy of ARS-2 in Patients With Chronic Spontaneous Urticaria.’ This study aims to evaluate the effectiveness of ARS-2 in treating patients with chronic spontaneous urticaria (CSU), a condition characterized by recurrent hives. The study’s significance lies in its potential to offer a new treatment option for individuals suffering from moderate to severe CSU flare-ups.

Business Operations and StrategyPrivate Placements and Financing
ARS Pharmaceuticals Secures $250 Million Credit Agreement
Positive
Sep 29, 2025

On September 29, 2025, ARS Pharmaceuticals, Inc. entered into a credit agreement with RA Capital Agency Services, LLC and other lenders for up to $250 million in term loans. The funds will be used for product development and general corporate purposes, with the first tranche of $100 million already advanced. This agreement is expected to support ARS Pharmaceuticals’ growth and enhance its market position, with implications for stakeholders including RA Capital, which holds a significant stake in the company.

The most recent analyst rating on (SPRY) stock is a Buy with a $25.00 price target. To see the full list of analyst forecasts on ARS Pharmaceuticals stock, see the SPRY Stock Forecast page.

Ars Pharmaceuticals Reports Strong Q2 Growth and Global Expansion
Sep 1, 2025

The recent earnings call from Ars Pharmaceuticals, Inc. painted a largely positive picture, with significant growth in revenue and prescription volume for their flagship product, Neffy. The company also highlighted its expanding global presence and commercial coverage. While there were concerns regarding high SG&A expenses and challenges with prior authorization requirements, the overall sentiment was optimistic, driven by strong revenue growth and strategic global expansion.

Legal Proceedings
ARS Pharmaceuticals Faces Patent Challenge from Lupin
Negative
Aug 28, 2025

On August 13, 2025, ARS Pharmaceuticals received a Paragraph IV certification notice from Lupin Inc., indicating that Lupin has filed an Abbreviated New Drug Application with the FDA to produce a generic version of ARS’s neffy© nasal spray before the expiration of several patents. ARS plans to defend its patents vigorously by filing a patent infringement lawsuit against Lupin, which could delay FDA approval of Lupin’s generic product by 30 months if filed within 45 days. The outcome of this legal action remains uncertain, but it could significantly impact ARS’s market position and intellectual property rights.

The most recent analyst rating on (SPRY) stock is a Hold with a $13.50 price target. To see the full list of analyst forecasts on ARS Pharmaceuticals stock, see the SPRY Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 18, 2025