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ARS Pharmaceuticals (SPRY)
NASDAQ:SPRY
US Market

ARS Pharmaceuticals (SPRY) AI Stock Analysis

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SPRY

ARS Pharmaceuticals

(NASDAQ:SPRY)

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Neutral 54 (OpenAI - 5.2)
Rating:54Neutral
Price Target:
$10.00
▼(-2.91% Downside)
The score is primarily held back by weak financial sustainability—large TTM losses and heavy free-cash-flow burn despite strong revenue growth and margins. Earnings call commentary is supportive due to accelerating Q3 revenue and strategic access initiatives backed by strong liquidity, while technicals are modestly constructive (above key shorter MAs, positive MACD) but not fully recovered versus the 200-day trend. Valuation remains constrained by negative earnings and no dividend support.
Positive Factors
Sustained Revenue Growth
Double-digit TTM revenue growth to $142.8M signals durable commercialization momentum for neffy, indicating expanding prescriber uptake and patient adoption that can underpin scalable top-line growth and improved operating leverage as fixed commercial costs are spread over higher volumes.
High Gross Margin / Unit Economics
Very high gross margins (~89%) point to attractive unit economics for neffy, which supports long-term margin sustainability as sales scale, provides flexibility on pricing/reimbursement, and creates room to invest in commercial expansion without immediate margin erosion.
Strong Liquidity and Low Leverage
A sizable cash balance plus a $250M facility and minimal legacy debt provide runway to fund commercialization, market-access programs, and international launches, reducing near-term financing risk and allowing strategic investments to build durable market share.
Negative Factors
Heavy Cash Burn
Material negative operating and free cash flow in the TTM indicates sizable cash burn from commercialization and operating investments; if losses persist this increases dependency on external financing and could pressure strategic flexibility and valuation over the medium term.
Ongoing Net Losses and Weak Returns
Sustained net losses and negative operating margins mean shareholder capital is being consumed and return metrics remain weak; absent durable margin expansion or cost scaling, the firm must convert revenue momentum into operating profitability to justify long-term capital allocation.
Single-Product Concentration Risk
Business reliance on a single lead product (neffy) concentrates revenue and execution risk: slower adoption, supply disruption, or competitive alternatives could materially harm cash flow and growth prospects, making diversification or portfolio expansion a structural priority.

ARS Pharmaceuticals (SPRY) vs. SPDR S&P 500 ETF (SPY)

ARS Pharmaceuticals Business Overview & Revenue Model

Company DescriptionARS Pharmaceuticals, Inc. develops ARS-1, a novel intranasal epinephrine spray with absorption technology for patients and their families at-risk of severe allergic reactions to food, medications, and insect bites. Its product includes Neffy, a low-dose intranasal epinephrine nasal spray. The company was incorporated in 2015 and is based in San Diego, California.
How the Company Makes MoneyARS Pharmaceuticals generates revenue primarily through the commercialization of its products, particularly neffy. The company monetizes its innovations through direct sales to healthcare providers and pharmacies, as well as potential partnerships with larger pharmaceutical companies for distribution and marketing. In addition to product sales, ARS may also benefit from licensing agreements, research collaborations, and government contracts related to public health initiatives. As neffy gains market acceptance, its sales are expected to be a significant contributor to the company's earnings, bolstered by ongoing investments in marketing and education to raise awareness among healthcare professionals and patients.

ARS Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 10, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Neutral
The call highlighted significant revenue growth and strategic initiatives like the 'Get Nephi On Us' program and global expansion. However, challenges such as temporary pauses in market share growth, data inaccuracies, and expected Q4 sales decline were noted.
Q3-2025 Updates
Positive Updates
Significant Revenue Growth
U.S. net product revenue for Nephi reached $31.3 million in Q3, representing a 2.5-fold increase from the prior quarter and exceeding consensus expectations of $28.3 million.
Global Expansion and Approvals
Nephi received approval in Japan with launch anticipated in 2025, expected approvals in Canada and China by 2026.
Positive Market Feedback and Real-World Data
Real-world data shows Nephi effectively treats anaphylaxis with a single dose in nine out of ten patients, aligning with epinephrine injections.
Launch of 'Get Nephi On Us' Program
Introduced a program to simplify access to Nephi with virtual prescriber interactions at no cost, anticipated to accelerate sales.
Strong Cash Position
Ended Q3 with $288 million in cash, cash equivalents, and short-term investments, supported by a $250 million term loan facility.
Negative Updates
Market Share Growth Challenge
Experienced a temporary pause in market share growth during the back-to-school season due to high patient volume and limited appointment time.
IQVIA Data Inaccuracy
IQVIA script data not accurately reflecting Nephi's revenue trajectory, with significant sales not captured in their data sets.
Anticipated Q4 Sales Decline
Q4 sales expected to decrease from Q3 due to typical seasonality and holiday decline in the epinephrine market.
Company Guidance
The guidance provided in the call highlighted several key metrics and strategic initiatives for ARS Pharmaceuticals. U.S. net product revenue for Nephi reached $31.3 million in Q3 2025, marking a 2.5-fold increase from the previous quarter and surpassing consensus expectations of $28.3 million. The company noted strong growth in new patient starts and overall demand, with Nephi's market share among new prescribers reaching 10.3%. The Get Nephi On Us program was introduced to facilitate easier access and prescriptions, aiming to drive sales growth despite typical seasonal declines in Q4. The company also reported a significant increase in consumer awareness, up from 20% pre-campaign to 56% by September. Additionally, the company ended Q3 with $288.2 million in cash and investments, bolstered by a $250 million term loan facility. The call emphasized ongoing investments in commercialization and international expansion, with expectations for approvals in Japan, Canada, and China by 2026.

ARS Pharmaceuticals Financial Statement Overview

Summary
Strong revenue scaling to $142.8M TTM (+27.1%) and very high gross margin (~89%) are positives, but TTM profitability deteriorated to a ~$80.0M net loss with deeply negative operating margins, alongside heavy cash burn (operating cash flow -$85.4M; FCF -$86.0M). Low leverage and positive equity help reduce balance-sheet risk, but current returns and cash generation are weak.
Income Statement
44
Neutral
Revenue has scaled sharply, reaching $142.8M in TTM (Trailing-Twelve-Months) and up 27.1% versus the prior period, signaling meaningful commercialization momentum. Gross profit remains strong in TTM (gross margin ~89%), indicating solid unit economics. However, profitability deteriorated materially in TTM with a net loss of ~$80.0M and deeply negative operating margins, reversing the modest profitability seen in 2024 (net margin ~9%). Overall, growth is a clear strength, but the current earnings profile is still highly pressured by operating costs.
Balance Sheet
73
Positive
The balance sheet is conservatively levered, with very low debt ($1.5M in TTM) and a minimal debt load relative to equity (debt-to-equity ~0.01), which reduces financial risk. Equity is positive and sizable in TTM ($147.7M), supporting flexibility. The main weakness is returns: TTM performance implies a weak return on equity (negative), reflecting that losses are currently consuming shareholder capital despite the low leverage.
Cash Flow
38
Negative
Cash generation has swung negative in TTM, with operating cash flow of -$85.4M and free cash flow of -$86.0M, indicating significant cash burn to support operations and growth. While 2024 showed positive operating and free cash flow, the latest TTM (Trailing-Twelve-Months) setback highlights volatility and increases funding dependency if losses persist. A relative positive is that free cash flow tracked net income closely in both profitable and loss periods, suggesting reported earnings are generally reflected in cash outcomes—though the absolute level is currently negative.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue142.77M89.15M30.00K1.32M5.51M17.84M
Gross Profit121.66M68.59M30.00K1.32M5.29M3.77M
EBITDA-83.07M-3.00M-67.45M-35.20M-19.24M-463.00K
Net Income-80.04M8.00M-54.37M-34.68M-20.24M-1.06M
Balance Sheet
Total Assets372.80M351.15M233.19M281.44M61.45M26.41M
Cash, Cash Equivalents and Short-Term Investments288.21M314.02M228.36M274.38M60.06M24.52M
Total Debt1.53M42.00K274.00K481.00K9.03M10.02M
Total Liabilities225.15M94.36M2.43M8.55M92.72M40.46M
Stockholders Equity147.66M256.80M230.76M272.89M-31.27M-14.05M
Cash Flow
Free Cash Flow-86.02M12.98M-59.44M-40.28M-17.62M8.15M
Operating Cash Flow-85.38M13.55M-59.27M-40.08M-17.56M9.07M
Investing Cash Flow-69.11M-106.10M-87.18M-199.00K-55.00K-917.00K
Financing Cash Flow174.38M72.40M6.90M190.73M53.16M5.10M

ARS Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price10.30
Price Trends
50DMA
10.41
Negative
100DMA
9.98
Positive
200DMA
12.56
Negative
Market Momentum
MACD
-0.16
Positive
RSI
45.28
Neutral
STOCH
37.09
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SPRY, the sentiment is Negative. The current price of 10.3 is below the 20-day moving average (MA) of 10.79, below the 50-day MA of 10.41, and below the 200-day MA of 12.56, indicating a bearish trend. The MACD of -0.16 indicates Positive momentum. The RSI at 45.28 is Neutral, neither overbought nor oversold. The STOCH value of 37.09 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SPRY.

ARS Pharmaceuticals Risk Analysis

ARS Pharmaceuticals disclosed 72 risk factors in its most recent earnings report. ARS Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ARS Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
$1.42B1,178.820.44%26.54%
65
Neutral
$2.10B-20.64-36.13%
57
Neutral
$1.34B-29.52-36.87%15.84%
54
Neutral
$987.50M-12.71-45.92%5459.66%-59.70%
54
Neutral
$999.21M-6.45-39.73%4.29%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$1.89B-27.31-28.07%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SPRY
ARS Pharmaceuticals
10.15
-2.37
-18.93%
TRVI
Trevi Therapeutics
11.48
7.40
181.37%
ORIC
Oric Pharmaceuticals
11.00
0.25
2.33%
PHAR
Pharming Group
17.26
8.84
105.04%
MAZE
Maze Therapeutics, Inc.
47.97
34.72
262.04%
SION
Sionna Therapeutics, Inc.
44.48
22.24
100.00%

ARS Pharmaceuticals Corporate Events

Business Operations and StrategyFinancial Disclosures
ARS Pharmaceuticals Reports Q3 2025 Financial Results
Neutral
Nov 10, 2025

On November 10, 2025, ARS Pharmaceuticals reported its third-quarter financial results, highlighting $32.5 million in revenue, primarily from U.S. sales of neffy®. The company is actively expanding its market presence with direct-to-consumer campaigns and strategic initiatives to increase prescriber confidence and patient access. Despite a net loss of $51.2 million, ARS Pharmaceuticals maintains a strong cash position to support its operations and growth. The company is also progressing with the global expansion of neffy, having received approval in Japan and launched EURneffy® in the U.K., with further regulatory approvals anticipated in Canada and China. These efforts are expected to enhance ARS Pharmaceuticals’ industry positioning and stakeholder engagement.

The most recent analyst rating on (SPRY) stock is a Buy with a $30.00 price target. To see the full list of analyst forecasts on ARS Pharmaceuticals stock, see the SPRY Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 13, 2026