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ARS Pharmaceuticals (SPRY)
NASDAQ:SPRY
US Market

ARS Pharmaceuticals (SPRY) AI Stock Analysis

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SPRY

ARS Pharmaceuticals

(NASDAQ:SPRY)

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Neutral 54 (OpenAI - 5.2)
Rating:54Neutral
Price Target:
$11.50
▲(1.05% Upside)
The score is primarily held back by weak financial sustainability—large TTM losses and heavy free-cash-flow burn despite strong revenue growth and margins. Earnings call commentary is supportive due to accelerating Q3 revenue and strategic access initiatives backed by strong liquidity, while technicals are modestly constructive (above key shorter MAs, positive MACD) but not fully recovered versus the 200-day trend. Valuation remains constrained by negative earnings and no dividend support.
Positive Factors
Revenue Growth & Unit Economics
ARS has scaled revenue substantially to $142.8M TTM with ~27% growth while maintaining very high gross margins (~89%). Durable unit economics support reinvestment in commercialization, provide pricing flexibility, and improve the odds of reaching operating leverage as volume scales.
Liquidity & Low Leverage
A strong cash balance and access to a $250M term loan, combined with minimal reported debt, materially extend runway for commercialization and international launches. This liquidity reduces near-term refinancing risk and allows sustained investment in demand generation and supply capacity over the medium term.
Partnered Global Expansion
Regulatory approval in China and an exclusive licensing deal with milestone and royalty economics create non-U.S. commercialization channels. Partnered market entry de-risks direct investment, accelerates revenue recognition via milestones/royalties, and supports scalable international footprint long term.
Negative Factors
Negative Cash Generation
Sustained negative operating and free cash flow of roughly -$85M TTM signals high cash burn to support growth. Persistent cash outflows increase dependence on external financing, raise dilution or leverage risk, and restrict the firm's ability to self-fund commercialization and international expansion if losses continue.
Sustained Net Losses & Weak Returns
A roughly $80M TTM net loss and reversal from prior modest profitability imply negative returns and weakened ROE. Continued operating losses erode shareholder equity, limit retained-capital for reinvestment, and prolong the timeline to self-sustaining margins, pressuring long-term value creation.
Product Concentration & Adoption Risks
Revenue is heavily concentrated in neffy, and management reported a temporary pause in market share growth plus expected seasonal Q4 declines. This concentration magnifies the impact of adoption cycles, prescriber access limits, and seasonality on company results, increasing revenue volatility and commercial execution risk.

ARS Pharmaceuticals (SPRY) vs. SPDR S&P 500 ETF (SPY)

ARS Pharmaceuticals Business Overview & Revenue Model

Company DescriptionARS Pharmaceuticals, Inc. develops ARS-1, a novel intranasal epinephrine spray with absorption technology for patients and their families at-risk of severe allergic reactions to food, medications, and insect bites. Its product includes Neffy, a low-dose intranasal epinephrine nasal spray. The company was incorporated in 2015 and is based in San Diego, California.
How the Company Makes MoneyARS Pharmaceuticals generates revenue primarily through the commercialization of its products, particularly neffy. The company monetizes its innovations through direct sales to healthcare providers and pharmacies, as well as potential partnerships with larger pharmaceutical companies for distribution and marketing. In addition to product sales, ARS may also benefit from licensing agreements, research collaborations, and government contracts related to public health initiatives. As neffy gains market acceptance, its sales are expected to be a significant contributor to the company's earnings, bolstered by ongoing investments in marketing and education to raise awareness among healthcare professionals and patients.

ARS Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 10, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Neutral
The call highlighted significant revenue growth and strategic initiatives like the 'Get Nephi On Us' program and global expansion. However, challenges such as temporary pauses in market share growth, data inaccuracies, and expected Q4 sales decline were noted.
Q3-2025 Updates
Positive Updates
Significant Revenue Growth
U.S. net product revenue for Nephi reached $31.3 million in Q3, representing a 2.5-fold increase from the prior quarter and exceeding consensus expectations of $28.3 million.
Global Expansion and Approvals
Nephi received approval in Japan with launch anticipated in 2025, expected approvals in Canada and China by 2026.
Positive Market Feedback and Real-World Data
Real-world data shows Nephi effectively treats anaphylaxis with a single dose in nine out of ten patients, aligning with epinephrine injections.
Launch of 'Get Nephi On Us' Program
Introduced a program to simplify access to Nephi with virtual prescriber interactions at no cost, anticipated to accelerate sales.
Strong Cash Position
Ended Q3 with $288 million in cash, cash equivalents, and short-term investments, supported by a $250 million term loan facility.
Negative Updates
Market Share Growth Challenge
Experienced a temporary pause in market share growth during the back-to-school season due to high patient volume and limited appointment time.
IQVIA Data Inaccuracy
IQVIA script data not accurately reflecting Nephi's revenue trajectory, with significant sales not captured in their data sets.
Anticipated Q4 Sales Decline
Q4 sales expected to decrease from Q3 due to typical seasonality and holiday decline in the epinephrine market.
Company Guidance
The guidance provided in the call highlighted several key metrics and strategic initiatives for ARS Pharmaceuticals. U.S. net product revenue for Nephi reached $31.3 million in Q3 2025, marking a 2.5-fold increase from the previous quarter and surpassing consensus expectations of $28.3 million. The company noted strong growth in new patient starts and overall demand, with Nephi's market share among new prescribers reaching 10.3%. The Get Nephi On Us program was introduced to facilitate easier access and prescriptions, aiming to drive sales growth despite typical seasonal declines in Q4. The company also reported a significant increase in consumer awareness, up from 20% pre-campaign to 56% by September. Additionally, the company ended Q3 with $288.2 million in cash and investments, bolstered by a $250 million term loan facility. The call emphasized ongoing investments in commercialization and international expansion, with expectations for approvals in Japan, Canada, and China by 2026.

ARS Pharmaceuticals Financial Statement Overview

Summary
ARS Pharmaceuticals has shown impressive revenue growth and improving net income, indicating operational improvements. The balance sheet is strong with low leverage and improving equity, although cash flow statements show caution due to high investing activities. Profitability remains a challenge, but recent trends show potential for future stabilization and growth.
Income Statement
ARS Pharmaceuticals showed significant revenue growth from 2023 to 2024, with total revenue jumping from $30,000 to $89,149,000, indicating strong potential. However, the company has struggled with profitability, evidenced by negative EBIT and EBITDA margins over the years. The net profit margin turned positive in 2024, a promising sign, but overall profitability remains inconsistent.
Balance Sheet
The balance sheet reveals a strong equity position, with stockholders' equity growing from negative figures in earlier years to a robust $256,798,000 in 2024. The debt-to-equity ratio is low, indicating low leverage risk. The equity ratio has improved, suggesting increased financial stability. However, fluctuations in total liabilities reflect some instability.
Cash Flow
Cash flow analysis shows a turnaround, with free cash flow becoming positive in 2024 after previous negative years. Operating cash flow to net income ratio improved, signaling better cash generation relative to income. However, investing cash flows were significantly negative, highlighting high capital expenditures or investments.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue142.77M89.15M30.00K1.32M5.51M17.84M
Gross Profit121.66M68.59M30.00K1.32M5.29M3.77M
EBITDA-83.07M-3.00M-67.45M-35.20M-19.24M-463.00K
Net Income-80.04M8.00M-54.37M-34.68M-20.24M-1.06M
Balance Sheet
Total Assets372.80M351.15M233.19M281.44M61.45M26.41M
Cash, Cash Equivalents and Short-Term Investments288.21M314.02M228.36M274.38M60.06M24.52M
Total Debt1.53M42.00K274.00K481.00K9.03M10.02M
Total Liabilities225.15M94.36M2.43M8.55M92.72M40.46M
Stockholders Equity147.66M256.80M230.76M272.89M-31.27M-14.05M
Cash Flow
Free Cash Flow-86.02M12.98M-59.44M-40.28M-17.62M8.15M
Operating Cash Flow-85.38M13.55M-59.27M-40.08M-17.56M9.07M
Investing Cash Flow-69.11M-106.10M-87.18M-199.00K-55.00K-917.00K
Financing Cash Flow174.38M72.40M6.90M190.73M53.16M5.10M

ARS Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price11.38
Price Trends
50DMA
9.76
Positive
100DMA
10.22
Positive
200DMA
12.77
Negative
Market Momentum
MACD
0.51
Positive
RSI
53.81
Neutral
STOCH
42.77
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SPRY, the sentiment is Positive. The current price of 11.38 is above the 20-day moving average (MA) of 11.11, above the 50-day MA of 9.76, and below the 200-day MA of 12.77, indicating a neutral trend. The MACD of 0.51 indicates Positive momentum. The RSI at 53.81 is Neutral, neither overbought nor oversold. The STOCH value of 42.77 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SPRY.

ARS Pharmaceuticals Risk Analysis

ARS Pharmaceuticals disclosed 72 risk factors in its most recent earnings report. ARS Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ARS Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
$1.29B1,304.170.44%26.54%
65
Neutral
$1.94B-17.83-36.13%
57
Neutral
$1.43B-30.41-36.87%15.84%
54
Neutral
$1.29B-14.04-45.92%5459.66%-59.70%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$891.11M-5.29-39.73%4.29%
47
Neutral
$1.75B-22.74-28.07%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SPRY
ARS Pharmaceuticals
11.38
0.02
0.18%
TRVI
Trevi Therapeutics
11.29
7.36
187.28%
ORIC
Oric Pharmaceuticals
9.15
-0.76
-7.67%
PHAR
Pharming Group
18.02
8.09
81.47%
MAZE
Maze Therapeutics, Inc.
40.19
25.19
167.93%
SION
Sionna Therapeutics, Inc.
36.34
14.10
63.40%

ARS Pharmaceuticals Corporate Events

Business Operations and StrategyFinancial Disclosures
ARS Pharmaceuticals Reports Q3 2025 Financial Results
Neutral
Nov 10, 2025

On November 10, 2025, ARS Pharmaceuticals reported its third-quarter financial results, highlighting $32.5 million in revenue, primarily from U.S. sales of neffy®. The company is actively expanding its market presence with direct-to-consumer campaigns and strategic initiatives to increase prescriber confidence and patient access. Despite a net loss of $51.2 million, ARS Pharmaceuticals maintains a strong cash position to support its operations and growth. The company is also progressing with the global expansion of neffy, having received approval in Japan and launched EURneffy® in the U.K., with further regulatory approvals anticipated in Canada and China. These efforts are expected to enhance ARS Pharmaceuticals’ industry positioning and stakeholder engagement.

The most recent analyst rating on (SPRY) stock is a Buy with a $30.00 price target. To see the full list of analyst forecasts on ARS Pharmaceuticals stock, see the SPRY Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 13, 2026