CompetitionSMMT faces competition from other manufacturers rapidly developing their VEGF-A/PD-(L)1 bispecific in combination regimens.
Development RisksRisks include delays in ivonescimab development, clinical trial failures, and possible medium-term dilution risk.
Market SkepticismThere is skepticism regarding whether a pharmacos would buy ivonescimab at a high price, considering other available options.